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Author :
Publisher :
ISBN 13 : 9780615974422
Total Pages : pages
Book Rating : 4.9/5 (744 download)
Download or read book MITRE Systems Engineering Guide written by and published by . This book was released on 2012-06-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mariusz Z. Ratajczak
Publisher : Springer Nature
ISBN 13 : 3030312062
Total Pages : 410 pages
Book Rating : 4.0/5 (33 download)
Download or read book Stem Cells written by Mariusz Z. Ratajczak and published by Springer Nature. This book was released on 2020-01-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.
Author : Charles Wesley Bailey
Publisher : Charles W Bailey Jr
ISBN 13 : 1453780815
Total Pages : 182 pages
Book Rating : 4.4/5 (537 download)
Download or read book Transforming Scholarly Publishing Through Open Access written by Charles Wesley Bailey and published by Charles W Bailey Jr. This book was released on 2010 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can scholarly journal articles and other scholarly works be made freely available on the Internet? The open access movement says "yes," and it is having a significant impact on scholarly publishing. There are two major open access strategies: (1) open access journals publish articles (typically peer-reviewed articles) that are free of charge and may be able to be reused under an open license (e.g., a Creative Commons license), and (2) self-archiving of digital e-prints (typically prepublication versions of articles) by authors in digital repositories, where they can be accessed free of charge and sometimes reused. Transforming Scholarly Publishing through Open Access: A Bibliography, which has over 1,100 references, provides in-depth coverage of published journal articles, books, and other works about the open access movement. Many references have links to freely available copies of included works.
Author : International Society for Technology in Education
Publisher : ISTE (Interntl Soc Tech Educ
ISBN 13 : 9781564842374
Total Pages : 28 pages
Book Rating : 4.8/5 (423 download)
Download or read book National Educational Technology Standards for Students written by International Society for Technology in Education and published by ISTE (Interntl Soc Tech Educ. This book was released on 2007 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: This booklet includes the full text of the ISTE Standards for Students, along with the Essential Conditions, profiles and scenarios.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309498511
Total Pages : 103 pages
Book Rating : 4.3/5 (94 download)
Download or read book The Role of NIH in Drug Development Innovation and Its Impact on Patient Access written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-27 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.
Author : Heung Jae Chun
Publisher : Springer
ISBN 13 : 9811309477
Total Pages : 533 pages
Book Rating : 4.8/5 (113 download)
Download or read book Novel Biomaterials for Regenerative Medicine written by Heung Jae Chun and published by Springer. This book was released on 2018-10-24 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth a wide range of new biomaterials that hold great promise for applications in regenerative medicine. The opening two sections are devoted to biomaterials designed to direct stem cell fate and regulate signaling pathways. Diverse novel functional biomaterials, including injectable nanocomposite hydrogels, electrosprayed nanoparticles, and waterborne polyurethane-based materials, are then discussed. The fourth section focuses on inorganic biomaterials, such as nanobioceramics, hydroxyapatite, and titanium dioxide. Finally, up-to-date information is provided on a wide range of smart natural biomaterials, ranging from silk fibroin-based scaffolds and collagen type I to chitosan, mussel-inspired biomaterials, and natural polymeric scaffolds. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth the latest enabling technologies for regenerative medicine.
Author :
Publisher :
ISBN 13 : 9788072485543
Total Pages : pages
Book Rating : 4.4/5 (855 download)
Download or read book 12th International Conference on Finance & Banking written by and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Wei-Shu Hu
Publisher : Springer
ISBN 13 : 3540340076
Total Pages : 179 pages
Book Rating : 4.5/5 (43 download)
Download or read book Cell Culture Engineering written by Wei-Shu Hu and published by Springer. This book was released on 2006-08-16 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.
Author : Garren Mulloy
Publisher : Oxford University Press
ISBN 13 : 0197644074
Total Pages : 259 pages
Book Rating : 4.1/5 (976 download)
Download or read book Defenders of Japan written by Garren Mulloy and published by Oxford University Press. This book was released on 2021-12-01 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Japan's post-war armed forces are a paradox, both embarrassing remnants of the past and valuable repositories of experience. This book charts the development of the Japan Self-Defense Forces (JSDF) from 1954 as both unorthodox military institutions and servants of a civil society that decries militarism. Investigating JSDF contributions to Japanese and global security, the evolution of such contributions during and after the Cold War, and their possible reconfiguration for Japan's security needs ahead, Garren Mulloy offers insight into the Forces' past, present and future. He explores the characteristics and contradictions of Japanese policy, including novel approaches in response to an increasingly assertive China, the latent threat of North Korea and contributory pressure from the US. Though the American alliance remains the core of Japanese security, new partnerships and international overtures will also shape the Forces' place in Prime Minister Abe's new vision of 'proactive contributions to peace'. Defenders of Japan deconstructs how the JSDF have adapted and will continue to adapt within domestic norms, caught between unresolved legacies of Japan's imperial past and a dynamically shifting balance of future global power.
Author : Alexandra Castilho
Publisher : Humana
ISBN 13 : 9781493927593
Total Pages : 0 pages
Book Rating : 4.9/5 (275 download)
Download or read book Glyco-Engineering written by Alexandra Castilho and published by Humana. This book was released on 2015-06-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conceived with the intention of providing an array of strategies and technologies currently in use for glyco-engineering distinct living organisms, this book contains a wide range of methods being developed to control the composition of carbohydrates and the properties of proteins through manipulations on the production host rather than in the protein itself. The first five sections deal with host-specific glyco-engineering and contain chapters that provide protocols for modifications of the glycosylation pathway in bacteria, yeast, insect, plants and mammalian cells, while the last two sections explore alternative approaches to host glyco-engineering and selected protocols for the analysis of the N-glycans and glyco-profiling by mass spectrometry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and extensive, Glyco-Engineering: Methods and Protocols offers vast options to help researchers to choose the expression system and approach that best suits their intended protein research or applications.
Author : Steven X. Hou
Publisher : Humana Press
ISBN 13 : 9781617378805
Total Pages : 0 pages
Book Rating : 4.3/5 (788 download)
Download or read book Germline Stem Cells written by Steven X. Hou and published by Humana Press. This book was released on 2014-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.
Author : Maurice Ptito
Publisher : Mdpi AG
ISBN 13 : 9783036526539
Total Pages : 498 pages
Book Rating : 4.5/5 (265 download)
Download or read book The Retina in Health and Disease written by Maurice Ptito and published by Mdpi AG. This book was released on 2021-12-27 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.
Author : Surajit Pathak
Publisher : Academic Press
ISBN 13 : 0128204133
Total Pages : 322 pages
Book Rating : 4.1/5 (282 download)
Download or read book Stem Cells and Aging written by Surajit Pathak and published by Academic Press. This book was released on 2021-03-17 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. - Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population - Addresses the effect of time and age on human stem cells - Includes chapters from contributors exploring the biology of stem cell aging around the globe
Author : Maria Cristina Galli
Publisher : Springer
ISBN 13 : 3319186183
Total Pages : 235 pages
Book Rating : 4.3/5 (191 download)
Download or read book Regulatory Aspects of Gene Therapy and Cell Therapy Products written by Maria Cristina Galli and published by Springer. This book was released on 2015-09-15 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the different regulatory pathways for gene therapy (GT) and cell therapy (CT) medicinal products implemented by national and international bodies throughout the world (e.g. North and South America, Europe, and Asia). Each chapter, authored by experts from various regulatory bodies throughout the international community, walks the reader through the applications of nonclinical research to translational clinical research to licensure for these innovative products. More specifically, each chapter offers insights into fundamental considerations that are essential for developers of CT and GT products, in the areas of product manufacturing, pharmacology and toxicology, and clinical trial design, as well as pertinent "must-know" guidelines and regulations. Regulatory Aspects of Gene Therapy and Cell Therapy Products: A Global Perspective is part of the American Society of Gene and Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students, clinicians, and researchers interested in gene and cell therapy and the regulation of pharmaceuticals.
Author : Mahmoud Aljurf
Publisher : Springer Nature
ISBN 13 : 3030644928
Total Pages : 181 pages
Book Rating : 4.0/5 (36 download)
Download or read book Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy written by Mahmoud Aljurf and published by Springer Nature. This book was released on 2021-02-19 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Specific areas of focus include document development and implementation, audits and validation, performance measurement, writing a quality management plan, the accreditation process, data management, and maintaining a quality management program. Written by experts in the field, Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy: A Practical Guide is a valuable resource for physicians, healthcare professionals, and laboratory staff involved in the creation and maintenance of a state-of-the-art HSCT and cellular therapy program.
Author : Filippo Crea
Publisher : Springer Science & Business Media
ISBN 13 : 8847053676
Total Pages : 263 pages
Book Rating : 4.8/5 (47 download)
Download or read book Coronary Microvascular Dysfunction written by Filippo Crea and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
Author : Antonello Mai
Publisher : Springer Nature
ISBN 13 : 3030429822
Total Pages : 569 pages
Book Rating : 4.0/5 (34 download)
Download or read book Chemical Epigenetics written by Antonello Mai and published by Springer Nature. This book was released on 2020-03-31 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
