Extracellular Vesicles

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1839164565
Total Pages : 358 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Extracellular Vesicles by : Wojciech Chrzanowski

Download or read book Extracellular Vesicles written by Wojciech Chrzanowski and published by Royal Society of Chemistry. This book was released on 2021-10-20 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The reader will then learn about the isolation of extracellular vesicles their physicochemical characterisation and therapeutic application of EVs in regenerative medicine as well as their potential as biomarkers in medical diagnostic. This book will also discuss the regulatory landscape of EVs. Bridging cell biology, biomaterials, biophysics and biomedical engineering the content of this book is written with a broad interdisciplinary audience in mind. Researchers, new and established will find this a must-have on their shelf.

The Liver

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Publisher : John Wiley & Sons
ISBN 13 : 1119436834
Total Pages : 3126 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-01-22 with total page 3126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Fungal Extracellular Vesicles

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Author :
Publisher : Springer Nature
ISBN 13 : 3030833917
Total Pages : 193 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Fungal Extracellular Vesicles by : Marcio Rodrigues

Download or read book Fungal Extracellular Vesicles written by Marcio Rodrigues and published by Springer Nature. This book was released on 2022-01-01 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host’s immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species. The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology.

Extracellular Vesicles in Health and Disease

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Publisher : CRC Press
ISBN 13 : 981441199X
Total Pages : 482 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Extracellular Vesicles in Health and Disease by : Paul Harrison

Download or read book Extracellular Vesicles in Health and Disease written by Paul Harrison and published by CRC Press. This book was released on 2014-05-02 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role

Exosomes and Microvesicles

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Author :
Publisher : Humana
ISBN 13 : 9781493967261
Total Pages : 0 pages
Book Rating : 4.9/5 (672 download)

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Book Synopsis Exosomes and Microvesicles by : Andrew F Hill

Download or read book Exosomes and Microvesicles written by Andrew F Hill and published by Humana. This book was released on 2016-12-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers methods for the analysis of extracellular vesicles (EV) that can be applied to isolated EVs from a wide variety of sources. This includes the use of electron microscopy, tunable resistance pulse sensing, and nanoparticle tracking analysis. The chapters in this book discuss EV cargoes containing proteins and genomic materials using a number of different approaches, and isolating EVs from platelets and neuronal cells and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Exosomes and Microvesicles: Methods and Protocols is a valuable resource containing methodologies for anyone interested in researching EVs.

Exosomes

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Publisher : Academic Press
ISBN 13 : 0128160543
Total Pages : 548 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Exosomes by : Larry Edelstein

Download or read book Exosomes written by Larry Edelstein and published by Academic Press. This book was released on 2019-10-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

Extracellular Vesicles

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Author :
Publisher : Academic Press
ISBN 13 : 0128206624
Total Pages : 314 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Extracellular Vesicles by :

Download or read book Extracellular Vesicles written by and published by Academic Press. This book was released on 2020-11-08 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Intercellular Communication in Plants

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Publisher : CRC Press
ISBN 13 : 9780849323638
Total Pages : 316 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Intercellular Communication in Plants by : Andrew J. Fleming

Download or read book Intercellular Communication in Plants written by Andrew J. Fleming and published by CRC Press. This book was released on 2005 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intercellular Communication in Plants provides an overview of intercellular signaling systems, capitalizing on the results of contemporary molecular biology. Many biological phenomena are controlled by intercellular signaling systems, initiated by messenger molecules. For example, intercellular communication channels are thought to be associated with a plant's growth and dormancy development - an important adaptive strategy for the survival and regrowth of temperate perennials. This volume is directed at researchers and professionals in plant biochemistry, physiology, cell biology and molecular biology, in both the academic and industrial sectors.

Extracellular Vesicles and Their Importance in Human Health

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789239435
Total Pages : 172 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Extracellular Vesicles and Their Importance in Human Health by : Ana Gil De Bona

Download or read book Extracellular Vesicles and Their Importance in Human Health written by Ana Gil De Bona and published by BoD – Books on Demand. This book was released on 2020-03-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.

Extracellular Vesicles

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Author :
Publisher : Academic Press
ISBN 13 : 0128206632
Total Pages : 316 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Extracellular Vesicles by :

Download or read book Extracellular Vesicles written by and published by Academic Press. This book was released on 2020-10-24 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Extracellular Vesicle-Based Therapeutics

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Author :
Publisher : Academic Press
ISBN 13 : 9780323902755
Total Pages : 366 pages
Book Rating : 4.9/5 (27 download)

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Book Synopsis Extracellular Vesicle-Based Therapeutics by : Tushar Patel

Download or read book Extracellular Vesicle-Based Therapeutics written by Tushar Patel and published by Academic Press. This book was released on 2022-10-15 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Vesicles-Based Therapeutics presents the exciting prospect of targeted delivery of drugs through exosomes. Taking a critical perspective, the Editor gathered worldwide experts both in academia and corporate settings to cover all aspects of the subject, from fundamental biological aspects to scaling up production, and regulation. The book is structured in six sections, each covering a distinct topic. Within each section, the authors and chapters were selected to provide a balanced coverage. Section I deals with the fundamentals of EV biology: types, formation, interactions and effects. Section II covers Extracellular Vesicles (EVs) isolation, and purification approaches. Section III presents EV production platforms, providing a framework and guidelines by which clinically usable and consistent EV therapeutics could be manufactured. Section IV covers preclinical studies and applications, reviewing studies that provide opportunities to identify disease-relevant indications for EV therapeutics and to guide their translation to clinical trials. Section V presents drug development and commercialization of EV therapeutics, covering considerations in regulatory approvals and market access for EV based therapeutics. Section VI covers clinical trials of EV therapeutics, outlining a framework for clinical evaluation, including study design and clinical trials strategies and examples of on-going trials of EV-based therapeutics. Extracellular Vesicles-Based Therapeutics is a complete resource for researchers in this exciting area. Its breadth of coverage makes it particularly interesting to pharmaceutical researchers exploring the potential of this platform for targeted drug delivery. Physicians, Regulators, Laboratory directors and Industry executives in biotechnology would also benefit from the contents in this book. Offers a critical view into the potential use of Exosomes for therapeutic use Brings experts in academic and industry together to cover biological principles all the way to manufacturing Strong translational characteristics, taking research to practice Covers scaling up processes and regulation

New Frontiers: Extracellular Vesicles

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Publisher : Springer Nature
ISBN 13 : 3030671712
Total Pages : 539 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis New Frontiers: Extracellular Vesicles by : Suresh Mathivanan

Download or read book New Frontiers: Extracellular Vesicles written by Suresh Mathivanan and published by Springer Nature. This book was released on 2021-03-29 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs. The book further discusses the biogenesis and secretion of these EVs, detailing the biological pathways and proteins involved. Research investigating the biological functions of EVs is rapidly increasing and the current knowledge around their role in progression of diseases such as cancer, neurodegeneration and metabolic disorders is discussed in multiple chapters. The implications of EVs in intercellular communication and the significance of biologically active cargo carried within these EVs are further examined. Moreover, the numerous applications of EVs in diagnostics and treatment of diseases are reviewed in detail, particularly their potential as biomarkers and drug delivery vehicles. Taken together, this book is a compilation of the key implications of EVs that are secreted by virtually all cell types. Readers will gain a perspective into the biology, functions and applications of EVs and their constantly evolving knowledge base.

Role of Exosomes in Biological Communication Systems

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Publisher : Springer Nature
ISBN 13 : 9811565996
Total Pages : 373 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Role of Exosomes in Biological Communication Systems by : Faisal A. Alzahrani

Download or read book Role of Exosomes in Biological Communication Systems written by Faisal A. Alzahrani and published by Springer Nature. This book was released on 2020-11-20 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.

Essential Current Concepts in Stem Cell Biology

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Publisher : Springer Nature
ISBN 13 : 3030339238
Total Pages : 247 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Essential Current Concepts in Stem Cell Biology by : Beate Brand-Saberi

Download or read book Essential Current Concepts in Stem Cell Biology written by Beate Brand-Saberi and published by Springer Nature. This book was released on 2020-01-03 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Extracellular Vesicles

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1803550546
Total Pages : 340 pages
Book Rating : 4.8/5 (35 download)

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Book Synopsis Extracellular Vesicles by :

Download or read book Extracellular Vesicles written by and published by BoD – Books on Demand. This book was released on 2022-07-20 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.

Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889454827
Total Pages : 245 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? by : Kulmira Nurgali

Download or read book Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? written by Kulmira Nurgali and published by Frontiers Media SA. This book was released on 2018-06-12 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.

Extracellular Vesicles

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Author :
Publisher : Springer Nature
ISBN 13 : 9819983657
Total Pages : 586 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Extracellular Vesicles by : Qian Wang

Download or read book Extracellular Vesicles written by Qian Wang and published by Springer Nature. This book was released on with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: