Exosomes

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Exosomes

Author : Larry Edelstein
Publisher : Academic Press
ISBN 13 : 0128160543
Total Pages : 548 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Exosomes by : Larry Edelstein

Download or read book Exosomes written by Larry Edelstein and published by Academic Press. This book was released on 2019-10-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

Role of Exosomes in Biological Communication Systems

Author : Faisal A. Alzahrani
Publisher : Springer Nature
ISBN 13 : 9811565996
Total Pages : 373 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Role of Exosomes in Biological Communication Systems by : Faisal A. Alzahrani

Download or read book Role of Exosomes in Biological Communication Systems written by Faisal A. Alzahrani and published by Springer Nature. This book was released on 2020-11-20 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.

Diagnostic and Therapeutic Applications of Exosomes in Cancer

Author : Mansoor M. Amiji
Publisher : Academic Press
ISBN 13 : 9780128127742
Total Pages : 0 pages
Book Rating : 4.1/5 (277 download)

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Book Synopsis Diagnostic and Therapeutic Applications of Exosomes in Cancer by : Mansoor M. Amiji

Download or read book Diagnostic and Therapeutic Applications of Exosomes in Cancer written by Mansoor M. Amiji and published by Academic Press. This book was released on 2018-05-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.

Mesenchymal Stem Cell Derived Exosomes

Author : Yaoliang Tang
Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 288 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Exosomes and Microvesicles

Author : Andrew F Hill
Publisher : Humana
ISBN 13 : 9781493967261
Total Pages : 0 pages
Book Rating : 4.9/5 (672 download)

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Book Synopsis Exosomes and Microvesicles by : Andrew F Hill

Download or read book Exosomes and Microvesicles written by Andrew F Hill and published by Humana. This book was released on 2016-12-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers methods for the analysis of extracellular vesicles (EV) that can be applied to isolated EVs from a wide variety of sources. This includes the use of electron microscopy, tunable resistance pulse sensing, and nanoparticle tracking analysis. The chapters in this book discuss EV cargoes containing proteins and genomic materials using a number of different approaches, and isolating EVs from platelets and neuronal cells and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Exosomes and Microvesicles: Methods and Protocols is a valuable resource containing methodologies for anyone interested in researching EVs.

Exosomes in Cardiovascular Diseases

Author : Junjie Xiao
Publisher : Springer
ISBN 13 : 9811043973
Total Pages : 307 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Exosomes in Cardiovascular Diseases by : Junjie Xiao

Download or read book Exosomes in Cardiovascular Diseases written by Junjie Xiao and published by Springer. This book was released on 2017-09-19 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.

The Liver

Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436834
Total Pages : 3126 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-01-22 with total page 3126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

RNA Exosome

Author : Torben Heick Jensen
Publisher : Springer Science & Business Media
ISBN 13 : 1441978410
Total Pages : 161 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis RNA Exosome by : Torben Heick Jensen

Download or read book RNA Exosome written by Torben Heick Jensen and published by Springer Science & Business Media. This book was released on 2011-06-29 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.

Exosomes

Author : Armando Meyer
Publisher : Nova Biomedical Books
ISBN 13 : 9781634857161
Total Pages : 92 pages
Book Rating : 4.8/5 (571 download)

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Book Synopsis Exosomes by : Armando Meyer

Download or read book Exosomes written by Armando Meyer and published by Nova Biomedical Books. This book was released on 2016 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exosomes are small (30-100 nm diameter) membrane enclosed vesicles of endosomal origin, released by a variety of cell types, which are capable of transferring biologically active macromolecules, such as proteins, lipids and RNA to other cells. Therefore, exosomes are important mediators of intercellular communication influencing physiological or pathological processes at recipient cells. In this book, Chapter One briefly reviews the knowledge gained on the molecular mechanisms underlying exosome formation and release. Chapter Two studies whether the Extracellular Vesicle (EV) Array can be utilized to phenotype unpurified small EVs (sEVs) from other body fluids such as urine, saliva, synovial fluid, cerebrospinal fluid (CSF), ascites, bone marrow (BM) and bronchoalveolar lavage fluid (BALF). Chapter Three examines the multifaceted roles of tumor-associated exosomes in the development and progression of cancer as well as the unique utility they present to detect, monitor, and therapeutically combat tumor occurrences. Chapter Four provides a review of the types of EVs encountered by sperm in the environment they traverse on their journey to the ampulla in the oviduct.

The Eukaryotic RNA Exosome

Author : John LaCava
Publisher : Springer Nature
ISBN 13 : 1493998226
Total Pages : 513 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis The Eukaryotic RNA Exosome by : John LaCava

Download or read book The Eukaryotic RNA Exosome written by John LaCava and published by Springer Nature. This book was released on 2019-11-25 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a cross-section of RNA exosome research protocols, applied to a diversity of model organisms. Chapters guide readers through methods that e.g. delineate eukaryotic exosomes’ origins in prokaryotes, probe its RNA substrates, adapter complexes and macromolecular interaction of networks, and establish critical structural-function relationships. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Eukaryotic RNA Exosome: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Exosomes as Therapeutic Systems

Author : Robert Steven Conlan
Publisher : Frontiers Media SA
ISBN 13 : 2889713768
Total Pages : 243 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Exosomes as Therapeutic Systems by : Robert Steven Conlan

Download or read book Exosomes as Therapeutic Systems written by Robert Steven Conlan and published by Frontiers Media SA. This book was released on 2021-10-01 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exosomes in Brain Health and Disease

Author : Konstantin Glebov
Publisher : Frontiers Media SA
ISBN 13 : 2889719308
Total Pages : 267 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Exosomes in Brain Health and Disease by : Konstantin Glebov

Download or read book Exosomes in Brain Health and Disease written by Konstantin Glebov and published by Frontiers Media SA. This book was released on 2022-06-06 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exosomes in Cardiovascular Diseases: Mechanism, Diagnosis and Therapy

Author : Hongyun Wang
Publisher : Frontiers Media SA
ISBN 13 : 2832506909
Total Pages : 151 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Exosomes in Cardiovascular Diseases: Mechanism, Diagnosis and Therapy by : Hongyun Wang

Download or read book Exosomes in Cardiovascular Diseases: Mechanism, Diagnosis and Therapy written by Hongyun Wang and published by Frontiers Media SA. This book was released on 2022-11-23 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exosomes: Message in a Vesicle

Author : Suman Dutta
Publisher : Frontiers Media SA
ISBN 13 : 2832502881
Total Pages : 259 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Exosomes: Message in a Vesicle by : Suman Dutta

Download or read book Exosomes: Message in a Vesicle written by Suman Dutta and published by Frontiers Media SA. This book was released on 2022-10-19 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Role of Exosomes in Metabolic and Endocrine Disease

Author : Ling-Qing Yuan
Publisher : Frontiers Media SA
ISBN 13 : 2889749126
Total Pages : 98 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The Role of Exosomes in Metabolic and Endocrine Disease by : Ling-Qing Yuan

Download or read book The Role of Exosomes in Metabolic and Endocrine Disease written by Ling-Qing Yuan and published by Frontiers Media SA. This book was released on 2022-04-07 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Wireless Intercellular Communications in Cardiac Pathology: The Role of Exosomes

Author : Mahmood Khan
Publisher : Frontiers Media SA
ISBN 13 : 2889661792
Total Pages : 123 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Wireless Intercellular Communications in Cardiac Pathology: The Role of Exosomes by : Mahmood Khan

Download or read book Wireless Intercellular Communications in Cardiac Pathology: The Role of Exosomes written by Mahmood Khan and published by Frontiers Media SA. This book was released on 2020-12-18 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Extracellular Vesicles and Their Importance in Human Health

Author : Ana Gil De Bona
Publisher : BoD – Books on Demand
ISBN 13 : 1789239435
Total Pages : 172 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Extracellular Vesicles and Their Importance in Human Health by : Ana Gil De Bona

Download or read book Extracellular Vesicles and Their Importance in Human Health written by Ana Gil De Bona and published by BoD – Books on Demand. This book was released on 2020-03-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.