Essential And Non Essential Metals

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Essential and Non-essential Metals

Author : Anuradha Mudipalli
Publisher : Springer
ISBN 13 : 3319554484
Total Pages : 235 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Essential and Non-essential Metals by : Anuradha Mudipalli

Download or read book Essential and Non-essential Metals written by Anuradha Mudipalli and published by Springer. This book was released on 2017-07-14 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present current state of understanding of the role of metals in human health and disease. As it will be difficult to cover all of the metals, about two scores of them, the authors will instead provide a detailed analysis of a select set of essential (Calcium, Magnesium, Selenium, Iron, copper and Zinc) and non-essential metals (Nickel, Chromium, Cadmium and Arsenic, Tungsten and Asbestos). Each chapter will have a dedicated section focusing on the binary role that some of these metals play, their carcinogenic and cancer therapeutics, by integrating epidemiological, experimental evidence with special emphasis and focus on molecular mechanisms involved in these processes. The biological analysis will also include emerging lines of evidence such as micro RNAS, kinase families, receptors, endoplasmic, mitochondrial players and epigenetics. As part of integrating the human, experimental and mechanistic data, as well as a detailed analysis into the modes of action for different cancer outcomes will be discussed in each chapter wherever deemed feasible. These approaches are ones in which no other book in this area has attempted to do.

Fish Physiology: Homeostasis and Toxicology of Essential Metals

Author :
Publisher : Academic Press
ISBN 13 : 9780123786364
Total Pages : 520 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Fish Physiology: Homeostasis and Toxicology of Essential Metals by :

Download or read book Fish Physiology: Homeostasis and Toxicology of Essential Metals written by and published by Academic Press. This book was released on 2011-08-11 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostasis and Toxicology of Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses. The companion volume, Homeostasis and Toxicology of Non-Essential Metals, Volume 31B, covers metals that have no known nutritive function in fish at present, but which are toxic at fairly low levels, such as Ag, Al, Cd, Pb, Hg, As, Sr, and U. In addition, three chapters in Volumes 31A and 31B on Basic Principles (Chapter 1, 31A), Field Studies and Ecological Integration (Chapter 9, 31A) and Modeling the Physiology and Toxicology of Metals (Chapter 9, 31B) act as integrative summaries and make these two volumes a vital set for readers. All major essential metals of interest are covered in metal-specific chapters Each metal-specific chapter is written by fish physiologists/toxicologists who are recognized authorities for that metal A common format is featured throughout this two volume edition

Metal Chelation in Medicine

Author : Robert R Crichton
Publisher : Royal Society of Chemistry
ISBN 13 : 1782623892
Total Pages : 336 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Metal Chelation in Medicine by : Robert R Crichton

Download or read book Metal Chelation in Medicine written by Robert R Crichton and published by Royal Society of Chemistry. This book was released on 2016-10-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic

Author : Peggy L. Carver
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110526980
Total Pages : 640 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic by : Peggy L. Carver

Download or read book Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic written by Peggy L. Carver and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-01-14 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.

Diet and Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Diet and Health by : National Research Council

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research

Download Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642698727
Total Pages : 209 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research by :

Download or read book Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific progress, more and more, makes it possible to relate disease to irreg ularities on a molecular basis. Both, diagnosis and cure can be targeted to a well defined biological structure. Modern medical research aims at the investigation of the interaction of molecules and bio-macro-molecules, formerly the area of chemis try, biochemistry and pharmacology. This series was founded to provide a vehicle for the dissemination of results in a multidisciplinary area of contemporary research. It will publish extensive review articles at a high level, that will relate a particular subject to the scopes of medical chemistry. Thus, information and useful references will be spread among the schol ars. Table of Contents Toxicity and Carcinogenicity of Essential and Non-essential Metals M. Costa, A. J. Kraker and S. R. Patierno (USA) .......... 1 Secondary Metabolites with Antibiotic Activity from the Primary Metabolism of Aromatic Amino Acids R. G. Werner (FRG) . . . . . . . . . . . . . . . . . . . . . .. . . 47 . . . . Clinical Pharmacology of Benzodiazepines U. Klotz (FRG) .............. .

Binding, Transport and Storage of Metal Ions in Biological Cells

Author : Wolfgang Maret
Publisher : Royal Society of Chemistry
ISBN 13 : 1782622829
Total Pages : 990 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Binding, Transport and Storage of Metal Ions in Biological Cells by : Wolfgang Maret

Download or read book Binding, Transport and Storage of Metal Ions in Biological Cells written by Wolfgang Maret and published by Royal Society of Chemistry. This book was released on 2014-07-09 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

Fish Physiology: Homeostasis and Toxicology of Non-Essential Metals

Author :
Publisher : Academic Press
ISBN 13 : 0123786355
Total Pages : 531 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Fish Physiology: Homeostasis and Toxicology of Non-Essential Metals by :

Download or read book Fish Physiology: Homeostasis and Toxicology of Non-Essential Metals written by and published by Academic Press. This book was released on 2011-07-01 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostasis and Toxicology of Non-Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Ag, Al, Cd, Pb, Hg, As, Sr, and U have no known nutritive function in fish at present, but are toxic at fairly low levels. The companion volume, Homeostasis and Toxicology of Essential Metals, Volume 31A, covers metals that are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr. In addition, three chapters in Volumes 31A and 31B on Basic Principles (Chapter 1, 31A), Field Studies and Ecological Integration (Chapter 9, 31A) and Modeling the Physiology and Toxicology of Metals (Chapter 9, 31B) act as integrative summaries and make these two volumes a vital set for readers. - All major essential metals of interest are covered in metal-specific chapters - Each metal-specific chapter is written by fish physiologists/toxicologists who are recognized authorities for that metal - A common format is featured throughout this two volume edition

Cellular Effects of Heavy Metals

Author : Gaspar Banfalvi
Publisher : Springer Science & Business Media
ISBN 13 : 9400704283
Total Pages : 348 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Cellular Effects of Heavy Metals by : Gaspar Banfalvi

Download or read book Cellular Effects of Heavy Metals written by Gaspar Banfalvi and published by Springer Science & Business Media. This book was released on 2011-03-02 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.

Heavy Metals in Soils

Author : Brian J. Alloway
Publisher : Springer Science & Business Media
ISBN 13 : 9400744706
Total Pages : 615 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Heavy Metals in Soils by : Brian J. Alloway

Download or read book Heavy Metals in Soils written by Brian J. Alloway and published by Springer Science & Business Media. This book was released on 2012-07-18 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of the book has been completely re-written, providing a wider scope and enhanced coverage. It covers the general principles of the natural occurrence, pollution sources, chemical analysis, soil chemical behaviour and soil-plant-animal relationships of heavy metals and metalloids, followed by a detailed coverage of 21 individual elements, including: antimony, arsenic, barium, cadmium, chromium, cobalt, copper, gold, lead, manganese, mercury, molybdenum, nickel, selenium, silver, thallium, tin, tungsten, uranium, vanadium and zinc. The book is highly relevant for those involved in environmental science, soil science, geochemistry, agronomy, environmental health, and environmental engineering, including specialists responsible for the management and clean-up of contaminated land.

Toxicological Profile for Zinc

Author :
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Zinc by :

Download or read book Toxicological Profile for Zinc written by and published by . This book was released on 1994 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Homeostasis and Toxicology of Non-essential Metals

Author : Chris M. Wood
Publisher : Academic Press
ISBN 13 : 0123786347
Total Pages : 531 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Homeostasis and Toxicology of Non-essential Metals by : Chris M. Wood

Download or read book Homeostasis and Toxicology of Non-essential Metals written by Chris M. Wood and published by Academic Press. This book was released on 2012 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostasis and Toxicology of Non-Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Ag, Al, Cd, Pb, Hg, As, Sr, and U have no known nutritive function in fish at present, but are toxic at fairly low levels.

Essentials of Toxicology for Health Protection

Author : David Baker
Publisher : Oxford University Press
ISBN 13 : 9780199652549
Total Pages : 368 pages
Book Rating : 4.6/5 (525 download)

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Book Synopsis Essentials of Toxicology for Health Protection by : David Baker

Download or read book Essentials of Toxicology for Health Protection written by David Baker and published by Oxford University Press. This book was released on 2012-03-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.

Concise Metals Engineering Data Book

Author : Joseph R. Davis
Publisher : ASM International
ISBN 13 : 161503983X
Total Pages : 257 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Concise Metals Engineering Data Book by : Joseph R. Davis

Download or read book Concise Metals Engineering Data Book written by Joseph R. Davis and published by ASM International. This book was released on 1997-01-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tef - Eragrostis Tef (Zucc.)

Author : Seyfu Ketema
Publisher : Bioversity International
ISBN 13 : 9290433043
Total Pages : 52 pages
Book Rating : 4.2/5 (94 download)

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Book Synopsis Tef - Eragrostis Tef (Zucc.) by : Seyfu Ketema

Download or read book Tef - Eragrostis Tef (Zucc.) written by Seyfu Ketema and published by Bioversity International. This book was released on 1997 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metal Transporters

Author : Jose M. Arguello
Publisher : Academic Press
ISBN 13 : 0123943906
Total Pages : 478 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Metal Transporters by : Jose M. Arguello

Download or read book Metal Transporters written by Jose M. Arguello and published by Academic Press. This book was released on 2012-10-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise

Metals in Cells

Author : Valeria Culotta
Publisher : John Wiley & Sons
ISBN 13 : 1118636864
Total Pages : 608 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Metals in Cells by : Valeria Culotta

Download or read book Metals in Cells written by Valeria Culotta and published by John Wiley & Sons. This book was released on 2016-03-16 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last three decades a lot of research on the role of metals in biochemistry and medicine has been done. As a result many structures of biomolecules with metals have been characterized and medicinal chemistry studied the effects of metal containing drugs. This new book (from the EIBC Book Series) covers recent advances made by top researchers in the field of metals in cells [the “metallome”] and include: regulated metal ion uptake and trafficking, sensing of metals within cells and across tissues, and identification of the vast cellular factors designed to orchestrate assembly of metal cofactor sites while minimizing toxic side reactions of metals. In addition, it features aspects of metals in disease, including the role of metals in neuro-degeneration, liver disease, and inflammation, as a way to highlight the detrimental effects of mishandling of metal trafficking and response to "foreign" metals. With the breadth of our recently acquired understanding of metals in cells, a book that features key aspects of cellular handling of inorganic elements is both timely and important. At this point in our understanding, it is worthwhile to step back and take an expansive view of how far our understanding has come, while also highlighting how much we still do not know. The content from this book will publish online, as part of EIBC in December 2013, find out more about the Encyclopedia of Inorganic and Bioinorganic Chemistry, the essential online resource for researchers and students working in all areas of inorganic and bioinorganic chemistry.