The Developing Genome

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Publisher : Oxford University Press, USA
ISBN 13 : 0199922349
Total Pages : 321 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Developing Genome by : David Scott Moore

Download or read book The Developing Genome written by David Scott Moore and published by Oxford University Press, USA. This book was released on 2015 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes bibliographical references (pages 275-300) and index

Epigenetics and Behavior

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Publisher : Academic Press
ISBN 13 : 0128016736
Total Pages : 400 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetics and Behavior by : F. Scott Hall

Download or read book Epigenetics and Behavior written by F. Scott Hall and published by Academic Press. This book was released on 2017-10-01 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Behavior: Exploring Biological Determinants of Behavior discusses the evolutionary basis of neurodevelopmental regulation of gene expression by experience (epigenetics). While many areas of scientific inquiry have sought to understand what determines the variation in human attributes (phenotypes) that have consistent trait-like features, including anxiety or fearlessness, aggressive or non-aggressive behavior, social or antisocial behavior, charitable or miserly traits, and so forth, this book takes a comprehensive approach. Over the lifespan of a particular individual, these traits, although flexible, are often highly consistent. The “nature-nurture or “genes versus environment discussion is one of the longstanding arguments in all philosophical inquiry. And now, as we stand on the threshold of a complete understanding of the most fundamental question about human nature, all a result of combined empirical and theoretical advances in epigenetics which influence developmental psychobiology and evolutionary biology, the science is rapidly progressing. With the advent of epigenetics, we now have a mechanism (or mechanisms, really) to explain how this process works at a molecular level – that is, evolutionary selected mechanisms of gene-environment interactions are literally “written into our genetic code. This book draws together the knowledge and ideas from the different fields that collectively have answered the “nature-nurture discussion. Integrates the findings of developmental psychobiology with epigenetics in an evolutionary context Written to convey a new perspective on epigenetic effects on behavior, while maintaining fluid writing prose for the uninformed reader Assembles knowledge from a number of fields, including developmental psychobiology, genomics, epigenetics, and evolutionary biology to paint a precise picture of epigenetic influences on personality

The Oxford Handbook of Developmental Psychology, Vol. 1

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Publisher : Oxford University Press
ISBN 13 : 0199958459
Total Pages : 1049 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Oxford Handbook of Developmental Psychology, Vol. 1 by : Philip David Zelazo

Download or read book The Oxford Handbook of Developmental Psychology, Vol. 1 written by Philip David Zelazo and published by Oxford University Press. This book was released on 2013-03-21 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a comprehensive survey of what is now known about psychological development, from birth to biological maturity, and it highlights how cultural, social, cognitive, neural, and molecular processes work together to yield human behavior and changes in human behavior.

Brain, Behavior and Epigenetics

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Publisher : Springer Science & Business Media
ISBN 13 : 3642174264
Total Pages : 320 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Brain, Behavior and Epigenetics by : Arturas Petronis

Download or read book Brain, Behavior and Epigenetics written by Arturas Petronis and published by Springer Science & Business Media. This book was released on 2011-05-19 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease? If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment? Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.

Developmental Human Behavioral Epigenetics

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Publisher : Academic Press
ISBN 13 : 0128192631
Total Pages : 190 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Developmental Human Behavioral Epigenetics by : Livio Provenzi

Download or read book Developmental Human Behavioral Epigenetics written by Livio Provenzi and published by Academic Press. This book was released on 2020-11-12 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy. Enables more effective study design and methods application in behavioral epigenetics research across human and animal models Examines findings in human behavioral epigenetics to-date Features contributions from leading international researchers in behavioral epigenetics

Epigenetics, Brain and Behavior

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Publisher : Springer
ISBN 13 : 9783642441080
Total Pages : 0 pages
Book Rating : 4.4/5 (41 download)

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Book Synopsis Epigenetics, Brain and Behavior by : Paolo Sassone Corsi

Download or read book Epigenetics, Brain and Behavior written by Paolo Sassone Corsi and published by Springer. This book was released on 2014-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molcular mechanisms implicated in epigentic control and how these may operte in concert. It will be critical to unravel how specifity is achieved. The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.

Mechanisms of Memory

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Publisher : Academic Press
ISBN 13 : 9780080959191
Total Pages : 362 pages
Book Rating : 4.9/5 (591 download)

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Book Synopsis Mechanisms of Memory by : J. David Sweatt

Download or read book Mechanisms of Memory written by J. David Sweatt and published by Academic Press. This book was released on 2009-09-28 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples

Epigenetic Regulation in the Nervous System

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Publisher : Academic Press
ISBN 13 : 0123944058
Total Pages : 374 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Epigenetic Regulation in the Nervous System by : J. David Sweatt

Download or read book Epigenetic Regulation in the Nervous System written by J. David Sweatt and published by Academic Press. This book was released on 2012-12-31 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions. Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia. BMA Medical Book Awards 2014 - Highly Commended, Neurology, British Medical Association BMA Medical Book Awards 2014 - First Prize, Neurology, British Medical Association 2013 PROSE Award winner for Best in Reference Works and Best Single Volume Reference in Science from the Association of American Publishers Presents a unified view of epigenetic mechanisms from behavior to genes and everything in between Discusses clinically relevant disorders in the context of epigenetics research, making the volume appealing to clinicians as well as basic scientists Provides numerous practical examples for the new investigator to facilitate implementation of research in neuroepigenetics

Epigenetics of Aging

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Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 469 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Handbook of Epigenetics

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Publisher : Academic Press
ISBN 13 : 0128054778
Total Pages : 682 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Handbook of Epigenetics by : Trygve Tollefsbol

Download or read book Handbook of Epigenetics written by Trygve Tollefsbol and published by Academic Press. This book was released on 2017-07-10 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders. Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine Written at a verbal and technical level that can be understood by scientists and college students Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials

Epigenetic Epidemiology

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Publisher : Springer Science & Business Media
ISBN 13 : 9400724950
Total Pages : 450 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Epigenetic Epidemiology by : Karin B. Michels

Download or read book Epigenetic Epidemiology written by Karin B. Michels and published by Springer Science & Business Media. This book was released on 2012-01-02 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Environmental Epigenetics

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Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 321 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

The Palgrave Handbook of Biology and Society

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Publisher : Springer
ISBN 13 : 1137528796
Total Pages : 941 pages
Book Rating : 4.1/5 (375 download)

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Book Synopsis The Palgrave Handbook of Biology and Society by : Maurizio Meloni

Download or read book The Palgrave Handbook of Biology and Society written by Maurizio Meloni and published by Springer. This book was released on 2017-10-27 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive handbook synthesizes the often-fractured relationship between the study of biology and the study of society. Bringing together a compelling array of interdisciplinary contributions, the authors demonstrate how nuanced attention to both the biological and social sciences opens up novel perspectives upon some of the most significant sociological, anthropological, philosophical and biological questions of our era. The six sections cover topics ranging from genomics and epigenetics, to neuroscience and psychology to social epidemiology and medicine. The authors collaboratively present state-of-the-art research and perspectives in some of the most intriguing areas of what can be called biosocial and biocultural approaches, demonstrating how quickly we are moving beyond the acrimonious debates that characterized the border between biology and society for most of the twentieth century. This landmark volume will be an extremely valuable resource for scholars and practitioners in all areas of the social and biological sciences. The chapter 'Ten Theses on the Subject of Biology and Politics: Conceptual, Methodological, and Biopolitical Considerations' is open access under a CC BY 4.0 license via link.springer.com. Versions of the chapters 'The Transcendence of the Social', 'Scrutinizing the Epigenetics Revolution', 'Species of Biocapital, 2008, and Speciating Biocapital, 2017' and 'Experimental Entanglements: Social Science and Neuroscience Beyond Interdisciplinarity' are available open access via third parties. For further information please see license information in the chapters or on link.springer.com.

The International Handbook on Psychopathic Disorders and the Law

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Publisher : John Wiley & Sons
ISBN 13 : 0470011858
Total Pages : 662 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The International Handbook on Psychopathic Disorders and the Law by : Alan Felthous

Download or read book The International Handbook on Psychopathic Disorders and the Law written by Alan Felthous and published by John Wiley & Sons. This book was released on 2008-03-10 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: The economic impact of society’s efforts to rehabilitate and contain psychopathically disordered individuals can be enormous. Understanding these disorders, developing valid assessment methods and providing safe, effective treatments is therefore of paramount importance. Reflecting the work of a truly international panel of experts from Europe, North America and Asia, the International Handbook on Psychopathic Disorders and the Law offers an in-depth, multidisciplinary look at key aspects of the development and etiology of psychopathic disorders, current methods of intervention, treatment and management, and how these disorders impact decision-making in civil and criminal law.

Introduction to Psychology

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Author :
Publisher : Hasanraza Ansari
ISBN 13 :
Total Pages : 810 pages
Book Rating : 4./5 ( download)

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Book Synopsis Introduction to Psychology by : Jennifer Walinga

Download or read book Introduction to Psychology written by Jennifer Walinga and published by Hasanraza Ansari. This book was released on with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to help students organize their thinking about psychology at a conceptual level. The focus on behaviour and empiricism has produced a text that is better organized, has fewer chapters, and is somewhat shorter than many of the leading books. The beginning of each section includes learning objectives; throughout the body of each section are key terms in bold followed by their definitions in italics; key takeaways, and exercises and critical thinking activities end each section.

Individual Development and Evolution

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Publisher : Psychology Press
ISBN 13 : 1135639329
Total Pages : 326 pages
Book Rating : 4.1/5 (356 download)

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Book Synopsis Individual Development and Evolution by : Gilbert Gottlieb

Download or read book Individual Development and Evolution written by Gilbert Gottlieb and published by Psychology Press. This book was released on 2001-09-01 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is intended to portray the interrelationship of heredity, individual development, and the evolution of species in a way that can be understood by nonspecialists. In striving to offer a straightforward historical exposition of the complex topic of nature and nurture, the author tells the story through a central cast of characters beginning with Lamarck in 1809 and ending with a synthesis of his own that depicts how extragenetic behavioral changes in individual development could be the first stages in the pathway leading to evolutionary change. On the way to that goal, he describes relevant conceptual aspects of genetics, embryological development, and evolutionary biology in a nontechnical and accurate way for students and colleagues in the behavioral and social sciences. The book presents a highly selected review as a prelude to the description of a developmental theory of the phenotype in which behavioral change leads eventually to evolutionary change. This book grew out of an invited interdisciplinary course of lectures for advanced undergraduate and graduate students at the University of Colorado, Boulder. Presenting the various ways about thinking about heredity, individual development, and evolution, the author had three goals in mind: *to establish the relevance of individual development to the evolution of species; *to describe the most appropriate way to think about or conceptualize heredity in relation to individual development; *to show that this somewhat unorthodox manner of conceptualizing heredity and individual development gives rise to a new way to think about the behavioral pathway leading to evolution. In conclusion, the present work will provide a contribution toward the possible dissolution of the nature-nurture dichotomy, as well as a contribution to evolutionary theory.

Epigenetics in Human Disease

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Publisher : Academic Press
ISBN 13 : 0123884152
Total Pages : 618 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Epigenetics in Human Disease by : Trygve O. Tollefsbol

Download or read book Epigenetics in Human Disease written by Trygve O. Tollefsbol and published by Academic Press. This book was released on 2012-07-26 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs