Enzymes Of The Cholinesterase Family

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Enzymes of the Cholinesterase Family

Author : A.S. Balasubramanian
Publisher : Springer Science & Business Media
ISBN 13 : 1489910514
Total Pages : 524 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Enzymes of the Cholinesterase Family by : A.S. Balasubramanian

Download or read book Enzymes of the Cholinesterase Family written by A.S. Balasubramanian and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth International Meeting on Cholinesterases convened in Madras, India, in September of 1994. The long and rich history and culture of India provided an excellent setting for the meeting. More than 120 delegates from Asia, Australia, Europe and North America heard 54 oral presentations and viewed 54 posters on current research on enzymes of the cholinesterase family. The aim of this book is to compile the presentations of the Fifth International Meeting on Cholinesterases into a volume that describes recent investigations on the structure and catalytic function of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and related enzymes, as well as studies on the molecular and cellular biology of these enzymes and the genes which encode them. Cholinesterases enjoy a long and storied history in diverse areas. In basic biochemical research, AChE is one of the best studied, though yet enigmatic, of enzymes. The efficient catalytic function of this enzyme presents the biochemist with a fundamental challenge in understanding the relationship between structure and function. AChE and BuChE belong to a family of proteins, the alB hydrolase fold family, whose constituents evolutionarily diverged from a common ancestor. Proteins in this family have a wide range of physiological functions. In commerce, AChE is a prime target for agricultural insect control, and for the development of therapeutic agents for Alzheimer's disease.

Cholinesterase

Author : Mary Whittaker
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cholinesterase by : Mary Whittaker

Download or read book Cholinesterase written by Mary Whittaker and published by S. Karger AG (Switzerland). This book was released on 1986 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Basic Neurochemistry

Author : Scott Brady
Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1120 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Basic Neurochemistry by : Scott Brady

Download or read book Basic Neurochemistry written by Scott Brady and published by Academic Press. This book was released on 2011-11-02 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475

The Biology of Cholinesterases

Author : Ann Silver
Publisher : North-Holland
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Biology of Cholinesterases by : Ann Silver

Download or read book The Biology of Cholinesterases written by Ann Silver and published by North-Holland. This book was released on 1974 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cholinesterase

Author : Cecelia J. White
Publisher :
ISBN 13 : 9781621006732
Total Pages : 0 pages
Book Rating : 4.0/5 (67 download)

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Book Synopsis Cholinesterase by : Cecelia J. White

Download or read book Cholinesterase written by Cecelia J. White and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholinesterase is a family of enzymes that catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. Cholinesterases are the target enzyme of numerous pesticides and chemical warfare agents and have been used for over two decades in the detection of these compounds. In this book, the authors present current research in the production, uses and health effects of cholinesterase. Topics discussed include cholinergic therapy for autistic spectrum disorders; acetylcholinesterase inhibitors in the treatment of Alzheimer's disease; use of fish brain and muscle acetylcholinesterase as a biomarker to monitor water pollution and the evolutionary aspects of molecular forms and biological functions of acetylcholinesterase. (Imprint: Nova)

Comparative Enzymology of Cholinesterases

Author : Serge N. Moralev
Publisher : Internat'l University Line
ISBN 13 : 9780972077422
Total Pages : 522 pages
Book Rating : 4.0/5 (774 download)

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Book Synopsis Comparative Enzymology of Cholinesterases by : Serge N. Moralev

Download or read book Comparative Enzymology of Cholinesterases written by Serge N. Moralev and published by Internat'l University Line. This book was released on 2007 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Marine Ecotoxicology

Author : Julián Blasco
Publisher : Academic Press
ISBN 13 : 012803372X
Total Pages : 334 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Marine Ecotoxicology by : Julián Blasco

Download or read book Marine Ecotoxicology written by Julián Blasco and published by Academic Press. This book was released on 2016-08-05 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine Ecotoxicology: Current Knowledge and Future Issues is the first unified resource to cover issues related to contamination, responses, and testing techniques of saltwater from a toxicological perspective. With its unprecedented focus on marine environments and logical chapter progression, this book is useful to graduate students, ecotoxicologists, risk assessors, and regulators involved or interested in marine waters. As human interaction with these environments increases, understanding of the pollutants and toxins introduced into the oceans becomes ever more critical, and this book builds a foundation of knowledge to assist scientists in studying, monitoring, and making decisions that affect both marine environments and human health. A team of world renowned experts provide detailed analyses of the most common contaminants in marine environments and explain the design and purpose of toxicity testing methods, while exploring the future of ecotoxicology studies in relation to the world’s oceans. As the threat of increasing pollution in marine environments becomes an ever more tangible reality, Marine Ecotoxicology offers insights and guidance to mitigate that threat. Provides practical tools and methods for assessing and monitoring the accumulation and effects of contaminants in marine environments Unites world renowned experts in marine ecotoxicology to deliver thorough and diverse perspectives Builds the foundation required for risk assessors and regulators to adequately assess and monitor the impact of pollution in marine environments Offers helpful insights and guidance to graduate students, ecotoxicologists, risk assessors, and regulators interested in mitigating threats to marine waters

Discovery and Development of Neuroprotective Agents from Natural Products

Author : Goutam Brahmachari
Publisher : Elsevier
ISBN 13 : 0128097698
Total Pages : 490 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Discovery and Development of Neuroprotective Agents from Natural Products by : Goutam Brahmachari

Download or read book Discovery and Development of Neuroprotective Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2017-05-18 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab

Movement Disorders

Author : Mark S. LeDoux
Publisher : Elsevier
ISBN 13 : 0124055168
Total Pages : 1258 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Movement Disorders by : Mark S. LeDoux

Download or read book Movement Disorders written by Mark S. LeDoux and published by Elsevier. This book was released on 2014-10-24 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration, and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. Introduces the scientific foundations for modern movement disorders research Contributing authors are internationally known experts Completely revised with 20% new material Provides a comprehensive discussion of genetics for each type of movement disorder Covers Parkinson's disease, Huntington's disease, dystonia, tremors, and tics

Toxicology of Organophosphate and Carbamate Compounds

Author : Ramesh C. Gupta
Publisher : Academic Press
ISBN 13 : 9780080543109
Total Pages : 768 pages
Book Rating : 4.5/5 (431 download)

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Book Synopsis Toxicology of Organophosphate and Carbamate Compounds by : Ramesh C. Gupta

Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C. Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans

Toxicological Survey of African Medicinal Plants

Author : Victor Kuete
Publisher : Elsevier
ISBN 13 : 0128004754
Total Pages : 744 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Toxicological Survey of African Medicinal Plants by : Victor Kuete

Download or read book Toxicological Survey of African Medicinal Plants written by Victor Kuete and published by Elsevier. This book was released on 2014-05-30 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems. Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology

Possible Long-term Health Effects of Short-term Exposure to Chemical Agents

Author :
Publisher : National Academies
ISBN 13 :
Total Pages : 118 pages
Book Rating : 4.1/5 (622 download)

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Book Synopsis Possible Long-term Health Effects of Short-term Exposure to Chemical Agents by :

Download or read book Possible Long-term Health Effects of Short-term Exposure to Chemical Agents written by and published by National Academies. This book was released on 1982 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309051401
Total Pages : 988 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Environmental Medicine by : Institute of Medicine

Download or read book Environmental Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1995-05-28 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.

Decoding Darkness

Author : Rudolph E Tanzi
Publisher : Basic Books
ISBN 13 : 0465012337
Total Pages : 314 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Decoding Darkness by : Rudolph E Tanzi

Download or read book Decoding Darkness written by Rudolph E Tanzi and published by Basic Books. This book was released on 2008-01-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.

Complications in Anesthesia

Author : John L. Atlee
Publisher : Elsevier Health Sciences
ISBN 13 : 1416022155
Total Pages : 1030 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Complications in Anesthesia by : John L. Atlee

Download or read book Complications in Anesthesia written by John L. Atlee and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 1030 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical text focuses on complications in the practice of anesthesia. Divided into sections similar to the thought processes involved in decision-making. Thumb indexing and cross-references are also included. All chapters have a case synopsis, problem analysis, and discussion of management and prevention.

Multidisciplinary Approaches to Cholinesterase Functions

Author : Avigdor Shafferman
Publisher : Springer
ISBN 13 : 9781461363286
Total Pages : 0 pages
Book Rating : 4.3/5 (632 download)

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Book Synopsis Multidisciplinary Approaches to Cholinesterase Functions by : Avigdor Shafferman

Download or read book Multidisciplinary Approaches to Cholinesterase Functions written by Avigdor Shafferman and published by Springer. This book was released on 2012-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acetylcholinesterase plays a key role in cholinergic transnnSSlOn. By rapid hydrolysis of the neurotransmitter acetylcholine the enzyme terminates the chemical impluse, thereby allowing rapid repetitive responses. Inhibitors of cholinesterases have important applications in agriculture - pest control, and in medicine - treatment of various disorders such as myasthenia gravis, glaucoma and management of Alzheimer's disease. These are some of the reasons for the special attraction of scientists from multiple disciplines such as neurobiology, pharmacology, chemistry, biochemistry, molecular biology and biotechnology to cholinesterase research. We have been fortunate to organize the 36th OHOLO conference on Multidisciplinary Approaches to Cholinesterase Functions at a time when this field of research is bursting with new concepts and ideas, brought about by the recent structural resolution of the catalytic subunit of acetylcholinesterase and by application of methodologies related to molecular genetics and protein engineering. This volume summarizes most of the important advances resulting from these developments as reflected in the OHOLO meeting.

Quantitative Functional Brain Imaging with Positron Emission Tomography

Author : Richard E. Carson
Publisher : Academic Press
ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Quantitative Functional Brain Imaging with Positron Emission Tomography by : Richard E. Carson

Download or read book Quantitative Functional Brain Imaging with Positron Emission Tomography written by Richard E. Carson and published by Academic Press. This book was released on 1998-08-28 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers