Toxicology Of Organophosphate And Carbamate Compounds

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Toxicology of Organophosphate and Carbamate Compounds

Author : Ramesh C. Gupta
Publisher : Academic Press
ISBN 13 : 9780080543109
Total Pages : 768 pages
Book Rating : 4.5/5 (431 download)

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Book Synopsis Toxicology of Organophosphate and Carbamate Compounds by : Ramesh C. Gupta

Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C. Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans

Clinical and Experimental Toxicology of Organophosphates and Carbamates

Author : Bryan Ballantyne
Publisher : Elsevier
ISBN 13 : 1483193659
Total Pages : 662 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Clinical and Experimental Toxicology of Organophosphates and Carbamates by : Bryan Ballantyne

Download or read book Clinical and Experimental Toxicology of Organophosphates and Carbamates written by Bryan Ballantyne and published by Elsevier. This book was released on 2017-01-31 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular events in delayed neuropathy. Other parts deal with the cardiac effects of anticholinesterase agents and the ecotoxicological consequences of interactions between avian esterases and organophosphorus compounds. These topics are followed by discussions on the analysis of the cutaneous and respiratory tract absorption of anticholinesterases and the use of organophosphorus compounds as chemical warfare agents. The final parts are devoted to the toxicity of anticholinesterases to aquatic organisms. The book can provide useful information to toxicologists, doctors, students, and researchers.

Toxicology and Pesticide Use in Relation to Wildlife, Organophosphorus, and Carbamate Compounds

Author : Gregory J. Smith
Publisher : CRC Press
ISBN 13 : 9780849387210
Total Pages : 178 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Toxicology and Pesticide Use in Relation to Wildlife, Organophosphorus, and Carbamate Compounds by : Gregory J. Smith

Download or read book Toxicology and Pesticide Use in Relation to Wildlife, Organophosphorus, and Carbamate Compounds written by Gregory J. Smith and published by CRC Press. This book was released on 1992-11-09 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphorus and carbonate pesticides are used as insecticides, herbicides, nematicides, acaricides, fungicides, rodenticides, and bird repellents throughout the world. Today, organophosphorus and carbamate pesticides use is widespread on agricultural crops, rangelands, forests, and wetlands. Toxicology and Pesticide Use: Organophosphorus and Carbamate Compounds summarizes what is known about these pesticides from wildlife toxicology literature and discusses the potential hazards to wildlife by examining toxicity, environmental persistence, and use patterns of the pesticides. This information is critical to anyone involved in agriculture or agribusiness because of the impact of recent EPA rulings regarding the administration of these chemicals to crops. The book will interest toxicologists, environmental toxicologists, agrichemists, and all researchers involved in the study of the impact of these chemicals on the environment.

Mammalian Toxicology of Insecticides

Author : Timothy C. Marrs
Publisher : Royal Society of Chemistry
ISBN 13 : 1849731918
Total Pages : 507 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Mammalian Toxicology of Insecticides by : Timothy C. Marrs

Download or read book Mammalian Toxicology of Insecticides written by Timothy C. Marrs and published by Royal Society of Chemistry. This book was released on 2012 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insects are more similar in structure and physiology to mammals than plants or fungi. Consequently, insecticides are often of greater toxicity to mammals than herbicides. This is particularly the case with neurotoxins. However, some insecticides are targeted at structures or hormonal systems specific to insects (insect growth regulators/chitin synthesis inhibitors) so are less harmful but can still be mildly haematotoxic. There are, therefore, issues specific to insecticides, which do not occur with other pesticides - hence the need for a book specifically on insecticide toxicology in mammals. The book starts with general issues relating to the mammalian toxicity of insecticides, including target/non-target specificity, nomenclature and metabolism of insecticides. It then goes on to discuss specific types of insecticides including: organochlorines; anticholinesterases; pyrethrum and synthetic pyrethroids; nicotine and the neonicotinoids; insect growth regulators/ecdysone agonists/chitin synthesis inhibitors; insecticides of natural origin; biological insecticides; and insecticides used in veterinary medicine.

Basic and Clinical Toxicology of Organophosphorus Compounds

Author : Mahdi Balali-Mood
Publisher : Springer Science & Business Media
ISBN 13 : 1447156250
Total Pages : 257 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Basic and Clinical Toxicology of Organophosphorus Compounds by : Mahdi Balali-Mood

Download or read book Basic and Clinical Toxicology of Organophosphorus Compounds written by Mahdi Balali-Mood and published by Springer Science & Business Media. This book was released on 2013-12-19 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the chemistry of Organophosphorus compounds (OPs), their mechanism of toxicity and the history of OPs from their initial discovery to the development of new compounds such as Novichoks. It details the harmful effects to human health both as a result of acute and chronic OP exposure and the necessary clinical management of affected patients to reduce their toxic side effects. The book also explains the detrimental effect that OPs have had on the environment and the efforts being made to prevent this in the future. Finally, the book looks at the incidents where OPs have been used as chemical warfare agents. Basic and Clinical Toxicology of Organophosphorus Compounds aims to act as a comprehensive guide to all aspects of OPs and is a key resource for clinical toxicologists and related health professionals involved in the prevention, diagnosis and clinical management of OP patients, toxicologists and other scientists involved in research on OPs including regulatory issues and postgraduate students in Toxicology and related fields.

Organophosphates And Health

Author : Stanley Feldman
Publisher : World Scientific
ISBN 13 : 1783261439
Total Pages : 511 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Organophosphates And Health by : Stanley Feldman

Download or read book Organophosphates And Health written by Stanley Feldman and published by World Scientific. This book was released on 2001-07-24 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few chemical compounds created by man have caused greater controversy than organophosphates. Conceived as insecticides, they have also been developed to become the most feared of chemical weapons. The control of vectors of diseases from which millions die or are disabled is heavily dependent on organophosphates, as are efforts to maintain food production in the face of uncontrolled population growth, diminishing arable land and the possibility of global warming. As the toxicity of organophosphates is non-specific, it has caused ill health and death in man, and has contributed to adverse ecological effects.This book, written by recognised experts, studies and presents information in a manner that basic scientists, medical personnel, environmentalists, agriculturists and those in public health and occupational medicine will find essential when considering the use of organophosphates in their disciplines. The text primarily covers health aspects, with discussions on related social, economic, environmental and agricultural issues that concern all inhabitants of the global village.

Organophosphates Chemistry, Fate, and Effects

Author : Janice E. Chambers
Publisher : Elsevier
ISBN 13 : 0080917267
Total Pages : 440 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Organophosphates Chemistry, Fate, and Effects by : Janice E. Chambers

Download or read book Organophosphates Chemistry, Fate, and Effects written by Janice E. Chambers and published by Elsevier. This book was released on 2013-10-22 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo

Toxicology of Organophosphate Poisoning

Author : Anuj Ranjan
Publisher : Springer Nature
ISBN 13 : 3030791289
Total Pages : 112 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Toxicology of Organophosphate Poisoning by : Anuj Ranjan

Download or read book Toxicology of Organophosphate Poisoning written by Anuj Ranjan and published by Springer Nature. This book was released on 2021-10-11 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the consequences of high agricultural pesticide use over the last few decades in the form of organophosphate poisoning. The authors provide a background overview of organophosphate compounds, their environmental toxicity, non-target exposures and cases of human poisoning. The authors also compile and analyze data from the last two decades to demonstrate the toxicological aspects of organophosphates, and how they can pose a threat to human health. Readers will learn about the clinical manifestation of organophosphate exposure in humans, as well as the enzymatic pathways and mechanisms by which organophosphates are processed in the body and cause harm. The book concludes by providing techniques, practices and recommendations for how to manage organophosphate exposure and poisoning. It will be useful for clinicians and public health professionals, scientists, medical practitioners, researchers and environmental toxicologists.

Pesticides in the Diets of Infants and Children

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309048753
Total Pages : 402 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council

Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

Handbook of Toxicology of Chemical Warfare Agents

Author : Ramesh C Gupta
Publisher : Academic Press
ISBN 13 : 0080922732
Total Pages : 1182 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Toxicology of Chemical Warfare Agents by : Ramesh C Gupta

Download or read book Handbook of Toxicology of Chemical Warfare Agents written by Ramesh C Gupta and published by Academic Press. This book was released on 2009-04-02 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with

Recognition and Management of Pesticide Poisonings (5th Ed. )

Author : J. Routt Reigart
Publisher : DIANE Publishing
ISBN 13 : 1437914527
Total Pages : 238 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Recognition and Management of Pesticide Poisonings (5th Ed. ) by : J. Routt Reigart

Download or read book Recognition and Management of Pesticide Poisonings (5th Ed. ) written by J. Routt Reigart and published by DIANE Publishing. This book was released on 2009-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

Environmental Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309051401
Total Pages : 988 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Environmental Medicine by : Institute of Medicine

Download or read book Environmental Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1995-05-28 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.

Veterinary Toxicology

Author : Ramesh C. Gupta
Publisher : Elsevier
ISBN 13 : 9780080481609
Total Pages : 1224 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Veterinary Toxicology by : Ramesh C. Gupta

Download or read book Veterinary Toxicology written by Ramesh C. Gupta and published by Elsevier. This book was released on 2011-04-28 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Carbamate Insecticides

Author : Ronald J. Kuhr
Publisher :
ISBN 13 : 9780878190522
Total Pages : 320 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis Carbamate Insecticides by : Ronald J. Kuhr

Download or read book Carbamate Insecticides written by Ronald J. Kuhr and published by . This book was released on 1976 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development and use; Chemistry and synthesis; Mode of action; Structure-activity relationnships; Toxicology; Metabolic reactions metabolismo; Biological and environmental stability; Residue methodology; Resistance and synergismo.

Chemical Warfare Toxicology

Author : Franz Worek
Publisher : Royal Society of Chemistry
ISBN 13 : 178262807X
Total Pages : 346 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Chemical Warfare Toxicology by : Franz Worek

Download or read book Chemical Warfare Toxicology written by Franz Worek and published by Royal Society of Chemistry. This book was released on 2016-05-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focussing on the most important representative nerve and blistering agents, whilst also covering other potential chemical warfare agents, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure.

Recognition and Management of Pesticide Poisonings

Author : Donald P. Morgan
Publisher : DIANE Publishing
ISBN 13 : 0788131761
Total Pages : 221 pages
Book Rating : 4.7/5 (881 download)

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Book Synopsis Recognition and Management of Pesticide Poisonings by : Donald P. Morgan

Download or read book Recognition and Management of Pesticide Poisonings written by Donald P. Morgan and published by DIANE Publishing. This book was released on 1996-07 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as guidance for emergency management, this manual deals almost entirely with short-term (acute) harmful effects of pesticides. Included is information on the health hazards of pesticides currently in use, along with current consensus recommendations for management of poisonings and injuries caused by them. Formatted for quick reference by through indexing, the book addresses poisoning by insecticides, pesticides, herbicides, fungicides, rodenticides, fumigants, and other solvents, acaricides, repellents, and adjuvants. Indexed by symptoms and signs and by chemical and product names. Illustrated.

Pesticides

Author : Sonia Soloneski
Publisher : BoD – Books on Demand
ISBN 13 : 9535112171
Total Pages : 241 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Pesticides by : Sonia Soloneski

Download or read book Pesticides written by Sonia Soloneski and published by BoD – Books on Demand. This book was released on 2014-02-20 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The edited book Pesticides - Toxic Aspects contains an overview of attractive researchers of pesticide toxicology that covers the hazardous effects of common chemical pesticide agents employed every day in our agricultural practices. The combination of experimental and theoretical pesticide investigations of current interest will make this book of significance to researchers, scientists, engineers, and graduate students who make use of those different investigations to understand the toxic aspects of pesticides. We hope that this book will continue to meet the expectations and needs of all interested in different aspects of pesticide toxicity.