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Empirical Likelihood Method In Survival Analysis
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Book Synopsis Empirical Likelihood Method in Survival Analysis by : Mai Zhou
Download or read book Empirical Likelihood Method in Survival Analysis written by Mai Zhou and published by CRC Press. This book was released on 2015-06-17 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Add the Empirical Likelihood to Your Nonparametric ToolboxEmpirical Likelihood Method in Survival Analysis explains how to use the empirical likelihood method for right censored survival data. The author uses R for calculating empirical likelihood and includes many worked out examples with the associated R code. The datasets and code are available
Book Synopsis Empirical Likelihood by : Art B. Owen
Download or read book Empirical Likelihood written by Art B. Owen and published by CRC Press. This book was released on 2001-05-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical likelihood provides inferences whose validity does not depend on specifying a parametric model for the data. Because it uses a likelihood, the method has certain inherent advantages over resampling methods: it uses the data to determine the shape of the confidence regions, and it makes it easy to combined data from multiple sources. It al
Book Synopsis Empirical Likelihood Methods in Biomedicine and Health by : Albert Vexler
Download or read book Empirical Likelihood Methods in Biomedicine and Health written by Albert Vexler and published by CRC Press. This book was released on 2018-09-03 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical Likelihood Methods in Biomedicine and Health provides a compendium of nonparametric likelihood statistical techniques in the perspective of health research applications. It includes detailed descriptions of the theoretical underpinnings of recently developed empirical likelihood-based methods. The emphasis throughout is on the application of the methods to the health sciences, with worked examples using real data. Provides a systematic overview of novel empirical likelihood techniques. Presents a good balance of theory, methods, and applications. Features detailed worked examples to illustrate the application of the methods. Includes R code for implementation. The book material is attractive and easily understandable to scientists who are new to the research area and may attract statisticians interested in learning more about advanced nonparametric topics including various modern empirical likelihood methods. The book can be used by graduate students majoring in biostatistics, or in a related field, particularly for those who are interested in nonparametric methods with direct applications in Biomedicine.
Book Synopsis Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials by : Mark Chang
Download or read book Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials written by Mark Chang and published by CRC Press. This book was released on 2019-03-20 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins University The pharmaceutical industry's approach to drug discovery and development has rapidly transformed in the last decade from the more traditional Research and Development (R & D) approach to a more innovative approach in which strategies are employed to compress and optimize the clinical development plan and associated timelines. However, these strategies are generally being considered on an individual trial basis and not as part of a fully integrated overall development program. Such optimization at the trial level is somewhat near-sighted and does not ensure cost, time, or development efficiency of the overall program. This book seeks to address this imbalance by establishing a statistical framework for overall/global clinical development optimization and providing tactics and techniques to support such optimization, including clinical trial simulations. Provides a statistical framework for achieve global optimization in each phase of the drug development process. Describes specific techniques to support optimization including adaptive designs, precision medicine, survival-endpoints, dose finding and multiple testing. Gives practical approaches to handling missing data in clinical trials using SAS. Looks at key controversial issues from both a clinical and statistical perspective. Presents a generous number of case studies from multiple therapeutic areas that help motivate and illustrate the statistical methods introduced in the book. Puts great emphasis on software implementation of the statistical methods with multiple examples of software code (both SAS and R). It is important for statisticians to possess a deep knowledge of the drug development process beyond statistical considerations. For these reasons, this book incorporates both statistical and "clinical/medical" perspectives.
Book Synopsis Survival Analysis Using S by : Mara Tableman
Download or read book Survival Analysis Using S written by Mara Tableman and published by CRC Press. This book was released on 2003-07-28 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival Analysis Using S: Analysis of Time-to-Event Data is designed as a text for a one-semester or one-quarter course in survival analysis for upper-level or graduate students in statistics, biostatistics, and epidemiology. Prerequisites are a standard pre-calculus first course in probability and statistics, and a course in applied linear regression models. No prior knowledge of S or R is assumed. A wide choice of exercises is included, some intended for more advanced students with a first course in mathematical statistics. The authors emphasize parametric log-linear models, while also detailing nonparametric procedures along with model building and data diagnostics. Medical and public health researchers will find the discussion of cut point analysis with bootstrap validation, competing risks and the cumulative incidence estimator, and the analysis of left-truncated and right-censored data invaluable. The bootstrap procedure checks robustness of cut point analysis and determines cut point(s). In a chapter written by Stephen Portnoy, censored regression quantiles - a new nonparametric regression methodology (2003) - is developed to identify important forms of population heterogeneity and to detect departures from traditional Cox models. By generalizing the Kaplan-Meier estimator to regression models for conditional quantiles, this methods provides a valuable complement to traditional Cox proportional hazards approaches.
Book Synopsis Counting Processes and Survival Analysis by : Thomas R. Fleming
Download or read book Counting Processes and Survival Analysis written by Thomas R. Fleming and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. "The book is a valuable completion of the literature in this field. It is written in an ambitious mathematical style and can be recommended to statisticians as well as biostatisticians." -Biometrische Zeitschrift "Not many books manage to combine convincingly topics from probability theory over mathematical statistics to applied statistics. This is one of them. The book has other strong points to recommend it: it is written with meticulous care, in a lucid style, general results being illustrated by examples from statistical theory and practice, and a bunch of exercises serve to further elucidate and elaborate on the text." -Mathematical Reviews "This book gives a thorough introduction to martingale and counting process methods in survival analysis thereby filling a gap in the literature." -Zentralblatt für Mathematik und ihre Grenzgebiete/Mathematics Abstracts "The authors have performed a valuable service to researchers in providing this material in [a] self-contained and accessible form. . . This text [is] essential reading for the probabilist or mathematical statistician working in the area of survival analysis." -Short Book Reviews, International Statistical Institute Counting Processes and Survival Analysis explores the martingale approach to the statistical analysis of counting processes, with an emphasis on the application of those methods to censored failure time data. This approach has proven remarkably successful in yielding results about statistical methods for many problems arising in censored data. A thorough treatment of the calculus of martingales as well as the most important applications of these methods to censored data is offered. Additionally, the book examines classical problems in asymptotic distribution theory for counting process methods and newer methods for graphical analysis and diagnostics of censored data. Exercises are included to provide practice in applying martingale methods and insight into the calculus itself.
Book Synopsis Advanced Survival Models by : Catherine Legrand
Download or read book Advanced Survival Models written by Catherine Legrand and published by CRC Press. This book was released on 2021-03-23 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival data analysis is a very broad field of statistics, encompassing a large variety of methods used in a wide range of applications, and in particular in medical research. During the last twenty years, several extensions of "classical" survival models have been developed to address particular situations often encountered in practice. This book aims to gather in a single reference the most commonly used extensions, such as frailty models (in case of unobserved heterogeneity or clustered data), cure models (when a fraction of the population will not experience the event of interest), competing risk models (in case of different types of event), and joint survival models for a time-to-event endpoint and a longitudinal outcome. Features Presents state-of-the art approaches for different advanced survival models including frailty models, cure models, competing risk models and joint models for a longitudinal and a survival outcome Uses consistent notation throughout the book for the different techniques presented Explains in which situation each of these models should be used, and how they are linked to specific research questions Focuses on the understanding of the models, their implementation, and their interpretation, with an appropriate level of methodological development for masters students and applied statisticians Provides references to existing R packages and SAS procedure or macros, and illustrates the use of the main ones on real datasets This book is primarily aimed at applied statisticians and graduate students of statistics and biostatistics. It can also serve as an introductory reference for methodological researchers interested in the main extensions of classical survival analysis.
Book Synopsis Statistical Modelling of Survival Data with Random Effects by : Il Do Ha
Download or read book Statistical Modelling of Survival Data with Random Effects written by Il Do Ha and published by Springer. This book was released on 2018-01-02 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a groundbreaking introduction to the likelihood inference for correlated survival data via the hierarchical (or h-) likelihood in order to obtain the (marginal) likelihood and to address the computational difficulties in inferences and extensions. The approach presented in the book overcomes shortcomings in the traditional likelihood-based methods for clustered survival data such as intractable integration. The text includes technical materials such as derivations and proofs in each chapter, as well as recently developed software programs in R (“frailtyHL”), while the real-world data examples together with an R package, “frailtyHL” in CRAN, provide readers with useful hands-on tools. Reviewing new developments since the introduction of the h-likelihood to survival analysis (methods for interval estimation of the individual frailty and for variable selection of the fixed effects in the general class of frailty models) and guiding future directions, the book is of interest to researchers in medical and genetics fields, graduate students, and PhD (bio) statisticians.
Book Synopsis Lifetime Data: Statistical Models And Methods by : Jayant V Deshpande
Download or read book Lifetime Data: Statistical Models And Methods written by Jayant V Deshpande and published by World Scientific Publishing Company. This book was released on 2006-01-23 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is meant for postgraduate modules that cover lifetime data in reliability and survival analysis as taught in statistics, engineering statistics and medical statistics courses. It is helpful for researchers who wish to choose appropriate models and methods for analyzing lifetime data. There is an extensive discussion on the concept and role of ageing in choosing appropriate models for lifetime data, with a special emphasis on tests of exponentiality. There are interesting contributions related to the topics of ageing, tests for exponentiality, competing risks and repairable systems. A special feature of this book is that it introduces the public domain R-software and explains how it can be used in computations of methods discussed in the book.
Book Synopsis Model-based Geostatistics for Global Public Health by : Peter J. Diggle
Download or read book Model-based Geostatistics for Global Public Health written by Peter J. Diggle and published by CRC Press. This book was released on 2019-03-04 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model-based Geostatistics for Global Public Health: Methods and Applications provides an introductory account of model-based geostatistics, its implementation in open-source software and its application in public health research. In the public health problems that are the focus of this book, the authors describe and explain the pattern of spatial variation in a health outcome or exposure measurement of interest. Model-based geostatistics uses explicit probability models and established principles of statistical inference to address questions of this kind. Features: Presents state-of-the-art methods in model-based geostatistics. Discusses the application these methods some of the most challenging global public health problems including disease mapping, exposure mapping and environmental epidemiology. Describes exploratory methods for analysing geostatistical data, including: diagnostic checking of residuals standard linear and generalized linear models; variogram analysis; Gaussian process models and geostatistical design issues. Includes a range of more complex geostatistical problems where research is ongoing. All of the results in the book are reproducible using publicly available R code and data-sets, as well as a dedicated R package. This book has been written to be accessible not only to statisticians but also to students and researchers in the public health sciences. The Authors Peter Diggle is Distinguished University Professor of Statistics in the Faculty of Health and Medicine, Lancaster University. He also holds honorary positions at the Johns Hopkins University School of Public Health, Columbia University International Research Institute for Climate and Society, and Yale University School of Public Health. His research involves the development of statistical methods for analyzing spatial and longitudinal data and their applications in the biomedical and health sciences. Dr Emanuele Giorgi is a Lecturer in Biostatistics and member of the CHICAS research group at Lancaster University, where he formerly obtained a PhD in Statistics and Epidemiology in 2015. His research interests involve the development of novel geostatistical methods for disease mapping, with a special focus on malaria and other tropical diseases. In 2018, Dr Giorgi was awarded the Royal Statistical Society Research Prize "for outstanding published contribution at the interface of statistics and epidemiology." He is also the lead developer of PrevMap, an R package where all the methodology found in this book has been implemented.
Book Synopsis Introduction to Empirical Processes and Semiparametric Inference by : Michael R. Kosorok
Download or read book Introduction to Empirical Processes and Semiparametric Inference written by Michael R. Kosorok and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kosorok’s brilliant text provides a self-contained introduction to empirical processes and semiparametric inference. These powerful research techniques are surprisingly useful for developing methods of statistical inference for complex models and in understanding the properties of such methods. This is an authoritative text that covers all the bases, and also a friendly and gradual introduction to the area. The book can be used as research reference and textbook.
Book Synopsis Analysis of Failure and Survival Data by : Peter J. Smith
Download or read book Analysis of Failure and Survival Data written by Peter J. Smith and published by CRC Press. This book was released on 2017-07-28 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Failure and Survival Data is an essential textbook for graduate-level students of survival analysis and reliability and a valuable reference for practitioners. It focuses on the many techniques that appear in popular software packages, including plotting product-limit survival curves, hazard plots, and probability plots in the context of censored data. The author integrates S-Plus and Minitab output throughout the text, along with a variety of real data sets so readers can see how the theory and methods are applied. He also incorporates exercises in each chapter that provide valuable problem-solving experience. In addition to all of this, the book also brings to light the most recent linear regression techniques. Most importantly, it includes a definitive account of the Buckley-James method for censored linear regression, found to be the best performing method when a Cox proportional hazards method is not appropriate. Applying the theories of survival analysis and reliability requires more background and experience than students typically receive at the undergraduate level. Mastering the contents of this book will help prepare students to begin performing research in survival analysis and reliability and provide seasoned practitioners with a deeper understanding of the field.
Book Synopsis Reliability and Survival Analysis by : Md. Rezaul Karim
Download or read book Reliability and Survival Analysis written by Md. Rezaul Karim and published by Springer. This book was released on 2019-08-09 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and standardizes statistical models and methods that can be directly applied to both reliability and survival analysis. These two types of analysis are widely used in many fields, including engineering, management, medicine, actuarial science, the environmental sciences, and the life sciences. Though there are a number of books on reliability analysis and a handful on survival analysis, there are virtually no books on both topics and their overlapping concepts. Offering an essential textbook, this book will benefit students, researchers, and practitioners in reliability and survival analysis, reliability engineering, biostatistics, and the biomedical sciences.
Book Synopsis The Frailty Model by : Luc Duchateau
Download or read book The Frailty Model written by Luc Duchateau and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Readers will find in the pages of this book a treatment of the statistical analysis of clustered survival data. Such data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. A typical example is the time to death in cancer patients, with patients clustered in hospitals. Frailty models provide a powerful tool to analyze clustered survival data. In this book different methods based on the frailty model are described and it is demonstrated how they can be used to analyze clustered survival data. All programs used for these examples are available on the Springer website.
Book Synopsis Statistical Analysis for Survival Data with Missing Information by : Bin Zhang
Download or read book Statistical Analysis for Survival Data with Missing Information written by Bin Zhang and published by . This book was released on 2009 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a branch of statistics, survival analysis, which is often referred to as "reliability theory" in engineering, has a long history. While in practical problems, some information might be missing. This dissertation discusses two types of missing information. The first type is caused by the censoring scheme, for example, the current status data. Several semiparametric models, e.g. the transformation models and the proportional odds models, are applied to the univariate and bivariate current status data. Efficient estimates are derived and the large sample properties of the estimates are provided. The other type is caused by sampling structure. It happens when the individuals do not have the same probabilities to be selected, for example, the stratified sampling. A biased sample problem is considered with the parameter of interest defined by some unbiased estimating equations. For the analysis, empirical likelihood approach is used and the likelihood ratio statistic is proved to follow a chi-square distribution asymptotically. Simulation studies and real data analysis are conducted to indicate that the presented approaches perform well in practical problems.
Book Synopsis Statistical Models and Methods for Reliability and Survival Analysis by : Vincent Couallier
Download or read book Statistical Models and Methods for Reliability and Survival Analysis written by Vincent Couallier and published by John Wiley & Sons. This book was released on 2013-12-31 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Models and Methods for Reliability and Survival Analysis brings together contributions by specialists in statistical theory as they discuss their applications providing up-to-date developments in methods used in survival analysis, statistical goodness of fit, stochastic processes for system reliability, amongst others. Many of these are related to the work of Professor M. Nikulin in statistics over the past 30 years. The authors gather together various contributions with a broad array of techniques and results, divided into three parts - Statistical Models and Methods, Statistical Models and Methods in Survival Analysis, and Reliability and Maintenance. The book is intended for researchers interested in statistical methodology and models useful in survival analysis, system reliability and statistical testing for censored and non-censored data.
Download or read book Loss Models written by Stuart A. Klugman and published by John Wiley & Sons. This book was released on 2012-01-25 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: An update of one of the most trusted books on constructing and analyzing actuarial models Written by three renowned authorities in the actuarial field, Loss Models, Third Edition upholds the reputation for excellence that has made this book required reading for the Society of Actuaries (SOA) and Casualty Actuarial Society (CAS) qualification examinations. This update serves as a complete presentation of statistical methods for measuring risk and building models to measure loss in real-world events. This book maintains an approach to modeling and forecasting that utilizes tools related to risk theory, loss distributions, and survival models. Random variables, basic distributional quantities, the recursive method, and techniques for classifying and creating distributions are also discussed. Both parametric and non-parametric estimation methods are thoroughly covered along with advice for choosing an appropriate model. Features of the Third Edition include: Extended discussion of risk management and risk measures, including Tail-Value-at-Risk (TVaR) New sections on extreme value distributions and their estimation Inclusion of homogeneous, nonhomogeneous, and mixed Poisson processes Expanded coverage of copula models and their estimation Additional treatment of methods for constructing confidence regions when there is more than one parameter The book continues to distinguish itself by providing over 400 exercises that have appeared on previous SOA and CAS examinations. Intriguing examples from the fields of insurance and business are discussed throughout, and all data sets are available on the book's FTP site, along with programs that assist with conducting loss model analysis. Loss Models, Third Edition is an essential resource for students and aspiring actuaries who are preparing to take the SOA and CAS preliminary examinations. It is also a must-have reference for professional actuaries, graduate students in the actuarial field, and anyone who works with loss and risk models in their everyday work. To explore our additional offerings in actuarial exam preparation visit www.wiley.com/go/actuarialexamprep.
