Elastic Shape Analysis of Curves and Surfaces

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)

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Book Synopsis Elastic Shape Analysis of Curves and Surfaces by : Zhe Su

Download or read book Elastic Shape Analysis of Curves and Surfaces written by Zhe Su and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The shape analysis of curves and surfaces has caught more and more attention in recent years. For curves in Euclidean space, the SRVF framework allows us to define and efficiently compute a distance on the shape space of curves. In this dissertation we give a generalization of the SRVF to curves with values in a homogeneous space and show that, under mild conditions, there always exist optimal reparametrizations realizing the quotient distance on the space of shapes. We give concrete examples to demonstrate the efficiency of our framework. Next, we introduce a diffeomorphism-invariant Riemannian metric on the space of vector valued one-forms. The metric is motivated by applications in the field of shape analysis and by connections to the Ebin metric on the space of all Riemannian metrics. We calculate the geodesic equations and obtain explicit solutions for the corresponding initial value problem. Using this, we study the geodesic and metric incompleteness of the space of one-forms and exhibit some totally geodesic subspaces. We also calculate its sectional curvature and observe that, depending on the dimensions of the base manifold and the ambient Euclidean space, it either has a semidefinite sign or admits both signs. After that, we give two data-driven frameworks for analyzing shapes of immersed surfaces in $\RR^3$. In the first framework, we introduce a 4-parameter family of elastic metrics on the space of surfaces as a pullback of a family of metrics on the space of vector-valued one-forms. This 4-parameter family of elastic metrics is invariant under rigid motions and reparametrizations. It generalizes a previously studied 3-parameter family of elastic metrics called the general elastic metric, and in particular the Square Root Normal Field (SRNF) metric, which has proved to be successful in various applications. In the second framework, we define a new representation for surfaces in $\RR^3$ by combining the induced surface metric and the SRNF of each surface. Using the DeWitt metric on the space of metrics and the $L^2$ metric on the space of SRNFs, we obtain a 3-parameter family of elastic metrics on surfaces, which forms an open subset of the general elastic metric. The new representation avoids the degeneracy of the SRNF representation, while it still results in an explicit extrinsic distance function on the space of surfaces and thus makes the framework computationally efficient. For both of these two frameworks we provide numerical algorithms and show several examples to validate the frameworks. The second framework, although it does not give a computation of geodesics, provides fast and accurate registration of surfaces. Finally we conclude with a summary of this dissertation and a discussion of possible future work.

Elastic Shape Analysis of Three-Dimensional Objects

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Publisher : Springer Nature
ISBN 13 : 3031018192
Total Pages : 169 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Elastic Shape Analysis of Three-Dimensional Objects by : Ian H. Jermyn

Download or read book Elastic Shape Analysis of Three-Dimensional Objects written by Ian H. Jermyn and published by Springer Nature. This book was released on 2022-05-31 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical analysis of shapes of 3D objects is an important problem with a wide range of applications. This analysis is difficult for many reasons, including the fact that objects differ in both geometry and topology. In this manuscript, we narrow the problem by focusing on objects with fixed topology, say objects that are diffeomorphic to unit spheres, and develop tools for analyzing their geometries. The main challenges in this problem are to register points across objects and to perform analysis while being invariant to certain shape-preserving transformations. We develop a comprehensive framework for analyzing shapes of spherical objects, i.e., objects that are embeddings of a unit sphere in ℝ, including tools for: quantifying shape differences, optimally deforming shapes into each other, summarizing shape samples, extracting principal modes of shape variability, and modeling shape variability associated with populations. An important strength of this framework is that it is elastic: it performs alignment, registration, and comparison in a single unified framework, while being invariant to shape-preserving transformations. The approach is essentially Riemannian in the following sense. We specify natural mathematical representations of surfaces of interest, and impose Riemannian metrics that are invariant to the actions of the shape-preserving transformations. In particular, they are invariant to reparameterizations of surfaces. While these metrics are too complicated to allow broad usage in practical applications, we introduce a novel representation, termed square-root normal fields (SRNFs), that transform a particular invariant elastic metric into the standard L2 metric. As a result, one can use standard techniques from functional data analysis for registering, comparing, and summarizing shapes. Specifically, this results in: pairwise registration of surfaces; computation of geodesic paths encoding optimal deformations; computation of Karcher means and covariances under the shape metric; tangent Principal Component Analysis (PCA) and extraction of dominant modes of variability; and finally, modeling of shape variability using wrapped normal densities. These ideas are demonstrated using two case studies: the analysis of surfaces denoting human bodies in terms of shape and pose variability; and the clustering and classification of the shapes of subcortical brain structures for use in medical diagnosis. This book develops these ideas without assuming advanced knowledge in differential geometry and statistics. We summarize some basic tools from differential geometry in the appendices, and introduce additional concepts and terminology as needed in the individual chapters.

A Statistical Theory for Shape Analysis of Curves and Surfaces with Applications in Image Analysis, Biometrics, Bioinformatics and Medical Diagnostics

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ISBN 13 :
Total Pages : 21 pages
Book Rating : 4.:/5 (713 download)

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Book Synopsis A Statistical Theory for Shape Analysis of Curves and Surfaces with Applications in Image Analysis, Biometrics, Bioinformatics and Medical Diagnostics by :

Download or read book A Statistical Theory for Shape Analysis of Curves and Surfaces with Applications in Image Analysis, Biometrics, Bioinformatics and Medical Diagnostics written by and published by . This book was released on 2010 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the five year period, this project has mainly been concerned about developing a theory for statistical analysis of shapes of objects, both two and three-dimensional. Focusing on the boundaries of these objects, our framework is for shape analysis of curves and surfaces. The main achievements were development of tools for: (1) Quantifying Shape Differences: Given any two objects, we can quantify differences between their shapes. (2) Achieve Desired Invariance: Our notion of shape is invariant to certain transformations of curves - rigid motion, scaling and re-parameterization. (3) Compute Summary Statistics: Given a collection of shapes and shape classes we can generate summary statistics - mean, covariance, etc, to characterize a shape class. (4) Stochastic Modeling: We have developed probability models that capture observed variability in shape classes. These models form priors for Bayesian inferences. (5) Statistical Inferences: We have studied statistical evaluations, such as hypothesis testing, likelihood ratios, performance bounds, etc, for shape analysis. The salient components of this differential geometric framework are following. First, we define a space of curves or surfaces by choosing a mathematical representation for these objects and establish a Hilbert submanifold(s) for such representations. Then, we choose a Riemannian metric, usually an elastic metric for measuring distances on such manifolds. We arrive at a shape manifold by imposing remaining invariances in the representation. For these shape spaces, we have developed two numerical techniques for computing geodesic paths. Finally, we define and compute empirical statistics, and define probability models on tangent bundles. The resulting statistical models are then used to characterize objects in images according to shapes, for using in object detection, tracking and recognition. We have demonstrated these tools in different application understanding.

Functional and Shape Data Analysis

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Publisher : Springer
ISBN 13 : 1493940201
Total Pages : 454 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Functional and Shape Data Analysis by : Anuj Srivastava

Download or read book Functional and Shape Data Analysis written by Anuj Srivastava and published by Springer. This book was released on 2016-10-03 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook for courses on function data analysis and shape data analysis describes how to define, compare, and mathematically represent shapes, with a focus on statistical modeling and inference. It is aimed at graduate students in analysis in statistics, engineering, applied mathematics, neuroscience, biology, bioinformatics, and other related areas. The interdisciplinary nature of the broad range of ideas covered—from introductory theory to algorithmic implementations and some statistical case studies—is meant to familiarize graduate students with an array of tools that are relevant in developing computational solutions for shape and related analyses. These tools, gleaned from geometry, algebra, statistics, and computational science, are traditionally scattered across different courses, departments, and disciplines; Functional and Shape Data Analysis offers a unified, comprehensive solution by integrating the registration problem into shape analysis, better preparing graduate students for handling future scientific challenges. Recently, a data-driven and application-oriented focus on shape analysis has been trending. This text offers a self-contained treatment of this new generation of methods in shape analysis of curves. Its main focus is shape analysis of functions and curves—in one, two, and higher dimensions—both closed and open. It develops elegant Riemannian frameworks that provide both quantification of shape differences and registration of curves at the same time. Additionally, these methods are used for statistically summarizing given curve data, performing dimension reduction, and modeling observed variability. It is recommended that the reader have a background in calculus, linear algebra, numerical analysis, and computation.

Geometry Driven Statistics

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Publisher : John Wiley & Sons
ISBN 13 : 1118866614
Total Pages : 432 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Geometry Driven Statistics by : Ian L. Dryden

Download or read book Geometry Driven Statistics written by Ian L. Dryden and published by John Wiley & Sons. This book was released on 2015-07-22 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely collection of advanced, original material in the area of statistical methodology motivated by geometric problems, dedicated to the influential work of Kanti V. Mardia This volume celebrates Kanti V. Mardia's long and influential career in statistics. A common theme unifying much of Mardia’s work is the importance of geometry in statistics, and to highlight the areas emphasized in his research this book brings together 16 contributions from high-profile researchers in the field. Geometry Driven Statistics covers a wide range of application areas including directional data, shape analysis, spatial data, climate science, fingerprints, image analysis, computer vision and bioinformatics. The book will appeal to statisticians and others with an interest in data motivated by geometric considerations. Summarizing the state of the art, examining some new developments and presenting a vision for the future, Geometry Driven Statistics will enable the reader to broaden knowledge of important research areas in statistics and gain a new appreciation of the work and influence of Kanti V. Mardia.

Riemannian Computing in Computer Vision

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Publisher : Springer
ISBN 13 : 3319229575
Total Pages : 382 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Riemannian Computing in Computer Vision by : Pavan K. Turaga

Download or read book Riemannian Computing in Computer Vision written by Pavan K. Turaga and published by Springer. This book was released on 2015-11-09 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive treatise on Riemannian geometric computations and related statistical inferences in several computer vision problems. This edited volume includes chapter contributions from leading figures in the field of computer vision who are applying Riemannian geometric approaches in problems such as face recognition, activity recognition, object detection, biomedical image analysis, and structure-from-motion. Some of the mathematical entities that necessitate a geometric analysis include rotation matrices (e.g. in modeling camera motion), stick figures (e.g. for activity recognition), subspace comparisons (e.g. in face recognition), symmetric positive-definite matrices (e.g. in diffusion tensor imaging), and function-spaces (e.g. in studying shapes of closed contours).

New Advances in Statistics and Data Science

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Publisher : Springer
ISBN 13 : 3319694162
Total Pages : 355 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis New Advances in Statistics and Data Science by : Ding-Geng Chen

Download or read book New Advances in Statistics and Data Science written by Ding-Geng Chen and published by Springer. This book was released on 2018-01-17 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is comprised of the presentations delivered at the 25th ICSA Applied Statistics Symposium held at the Hyatt Regency Atlanta, on June 12-15, 2016. This symposium attracted more than 700 statisticians and data scientists working in academia, government, and industry from all over the world. The theme of this conference was the “Challenge of Big Data and Applications of Statistics,” in recognition of the advent of big data era, and the symposium offered opportunities for learning, receiving inspirations from old research ideas and for developing new ones, and for promoting further research collaborations in the data sciences. The invited contributions addressed rich topics closely related to big data analysis in the data sciences, reflecting recent advances and major challenges in statistics, business statistics, and biostatistics. Subsequently, the six editors selected 19 high-quality presentations and invited the speakers to prepare full chapters for this book, which showcases new methods in statistics and data sciences, emerging theories, and case applications from statistics, data science and interdisciplinary fields. The topics covered in the book are timely and have great impact on data sciences, identifying important directions for future research, promoting advanced statistical methods in big data science, and facilitating future collaborations across disciplines and between theory and practice.

Algorithmic Advances in Riemannian Geometry and Applications

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Publisher : Springer
ISBN 13 : 3319450263
Total Pages : 216 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Algorithmic Advances in Riemannian Geometry and Applications by : Hà Quang Minh

Download or read book Algorithmic Advances in Riemannian Geometry and Applications written by Hà Quang Minh and published by Springer. This book was released on 2016-10-05 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a selection of the most recent algorithmic advances in Riemannian geometry in the context of machine learning, statistics, optimization, computer vision, and related fields. The unifying theme of the different chapters in the book is the exploitation of the geometry of data using the mathematical machinery of Riemannian geometry. As demonstrated by all the chapters in the book, when the data is intrinsically non-Euclidean, the utilization of this geometrical information can lead to better algorithms that can capture more accurately the structures inherent in the data, leading ultimately to better empirical performance. This book is not intended to be an encyclopedic compilation of the applications of Riemannian geometry. Instead, it focuses on several important research directions that are currently actively pursued by researchers in the field. These include statistical modeling and analysis on manifolds,optimization on manifolds, Riemannian manifolds and kernel methods, and dictionary learning and sparse coding on manifolds. Examples of applications include novel algorithms for Monte Carlo sampling and Gaussian Mixture Model fitting, 3D brain image analysis,image classification, action recognition, and motion tracking.

Geometric Science of Information

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Publisher : Springer
ISBN 13 : 3030269809
Total Pages : 764 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Geometric Science of Information by : Frank Nielsen

Download or read book Geometric Science of Information written by Frank Nielsen and published by Springer. This book was released on 2019-08-19 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 4th International Conference on Geometric Science of Information, GSI 2019, held in Toulouse, France, in August 2019. The 79 full papers presented in this volume were carefully reviewed and selected from 105 submissions. They cover all the main topics and highlights in the domain of geometric science of information, including information geometry manifolds of structured data/information and their advanced applications.

Processing, Analyzing and Learning of Images, Shapes, and Forms:

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Publisher : North Holland
ISBN 13 : 0444641408
Total Pages : 704 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Processing, Analyzing and Learning of Images, Shapes, and Forms: by : Xue-Cheng Tai

Download or read book Processing, Analyzing and Learning of Images, Shapes, and Forms: written by Xue-Cheng Tai and published by North Holland. This book was released on 2019-10 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Processing, Analyzing and Learning of Images, Shapes, and Forms: Part 2, Volume 20, surveys the contemporary developments relating to the analysis and learning of images, shapes and forms, covering mathematical models and quick computational techniques. Chapter cover Alternating Diffusion: A Geometric Approach for Sensor Fusion, Generating Structured TV-based Priors and Associated Primal-dual Methods, Graph-based Optimization Approaches for Machine Learning, Uncertainty Quantification and Networks, Extrinsic Shape Analysis from Boundary Representations, Efficient Numerical Methods for Gradient Flows and Phase-field Models, Recent Advances in Denoising of Manifold-Valued Images, Optimal Registration of Images, Surfaces and Shapes, and much more. Covers contemporary developments relating to the analysis and learning of images, shapes and forms Presents mathematical models and quick computational techniques relating to the topic Provides broad coverage, with sample chapters presenting content on Alternating Diffusion and Generating Structured TV-based Priors and Associated Primal-dual Methods

Academic Press Library in Signal Processing, Volume 6

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Publisher : Academic Press
ISBN 13 : 0128119004
Total Pages : 460 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Academic Press Library in Signal Processing, Volume 6 by :

Download or read book Academic Press Library in Signal Processing, Volume 6 written by and published by Academic Press. This book was released on 2017-11-28 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Academic Press Library in Signal Processing, Volume 6: Image and Video Processing and Analysis and Computer Vision is aimed at university researchers, post graduate students and R&D engineers in the industry, providing a tutorial-based, comprehensive review of key topics and technologies of research in both image and video processing and analysis and computer vision. The book provides an invaluable starting point to the area through the insight and understanding that it provides. With this reference, readers will quickly grasp an unfamiliar area of research, understand the underlying principles of a topic, learn how a topic relates to other areas, and learn of research issues yet to be resolved. Presents a quick tutorial of reviews of important and emerging topics of research Explores core principles, technologies, algorithms and applications Edited and contributed by international leading figures in the field Includes comprehensive references to journal articles and other literature upon which to build further, more detailed knowledge

Computer Vision – ECCV 2012

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Publisher : Springer
ISBN 13 : 3642337155
Total Pages : 897 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Computer Vision – ECCV 2012 by : Andrew Fitzgibbon

Download or read book Computer Vision – ECCV 2012 written by Andrew Fitzgibbon and published by Springer. This book was released on 2012-09-26 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seven-volume set comprising LNCS volumes 7572-7578 constitutes the refereed proceedings of the 12th European Conference on Computer Vision, ECCV 2012, held in Florence, Italy, in October 2012. The 408 revised papers presented were carefully reviewed and selected from 1437 submissions. The papers are organized in topical sections on geometry, 2D and 3D shapes, 3D reconstruction, visual recognition and classification, visual features and image matching, visual monitoring: action and activities, models, optimisation, learning, visual tracking and image registration, photometry: lighting and colour, and image segmentation.

Shape Perception in Human and Computer Vision

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Publisher : Springer Science & Business Media
ISBN 13 : 144715195X
Total Pages : 505 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Shape Perception in Human and Computer Vision by : Sven J. Dickinson

Download or read book Shape Perception in Human and Computer Vision written by Sven J. Dickinson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and authoritative text/reference presents a unique, multidisciplinary perspective on Shape Perception in Human and Computer Vision. Rather than focusing purely on the state of the art, the book provides viewpoints from world-class researchers reflecting broadly on the issues that have shaped the field. Drawing upon many years of experience, each contributor discusses the trends followed and the progress made, in addition to identifying the major challenges that still lie ahead. Topics and features: examines each topic from a range of viewpoints, rather than promoting a specific paradigm; discusses topics on contours, shape hierarchies, shape grammars, shape priors, and 3D shape inference; reviews issues relating to surfaces, invariants, parts, multiple views, learning, simplicity, shape constancy and shape illusions; addresses concepts from the historically separate disciplines of computer vision and human vision using the same “language” and methods.

3D Shape Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 1119405106
Total Pages : 368 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis 3D Shape Analysis by : Hamid Laga

Download or read book 3D Shape Analysis written by Hamid Laga and published by John Wiley & Sons. This book was released on 2019-01-07 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: An in-depth description of the state-of-the-art of 3D shape analysis techniques and their applications This book discusses the different topics that come under the title of "3D shape analysis". It covers the theoretical foundations and the major solutions that have been presented in the literature. It also establishes links between solutions proposed by different communities that studied 3D shape, such as mathematics and statistics, medical imaging, computer vision, and computer graphics. The first part of 3D Shape Analysis: Fundamentals, Theory, and Applications provides a review of the background concepts such as methods for the acquisition and representation of 3D geometries, and the fundamentals of geometry and topology. It specifically covers stereo matching, structured light, and intrinsic vs. extrinsic properties of shape. Parts 2 and 3 present a range of mathematical and algorithmic tools (which are used for e.g., global descriptors, keypoint detectors, local feature descriptors, and algorithms) that are commonly used for the detection, registration, recognition, classification, and retrieval of 3D objects. Both also place strong emphasis on recent techniques motivated by the spread of commodity devices for 3D acquisition. Part 4 demonstrates the use of these techniques in a selection of 3D shape analysis applications. It covers 3D face recognition, object recognition in 3D scenes, and 3D shape retrieval. It also discusses examples of semantic applications and cross domain 3D retrieval, i.e. how to retrieve 3D models using various types of modalities, e.g. sketches and/or images. The book concludes with a summary of the main ideas and discussions of the future trends. 3D Shape Analysis: Fundamentals, Theory, and Applications is an excellent reference for graduate students, researchers, and professionals in different fields of mathematics, computer science, and engineering. It is also ideal for courses in computer vision and computer graphics, as well as for those seeking 3D industrial/commercial solutions.

Computer Vision -- ECCV 2014

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Publisher : Springer
ISBN 13 : 3319106023
Total Pages : 878 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Computer Vision -- ECCV 2014 by : David Fleet

Download or read book Computer Vision -- ECCV 2014 written by David Fleet and published by Springer. This book was released on 2014-08-14 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seven-volume set comprising LNCS volumes 8689-8695 constitutes the refereed proceedings of the 13th European Conference on Computer Vision, ECCV 2014, held in Zurich, Switzerland, in September 2014. The 363 revised papers presented were carefully reviewed and selected from 1444 submissions. The papers are organized in topical sections on tracking and activity recognition; recognition; learning and inference; structure from motion and feature matching; computational photography and low-level vision; vision; segmentation and saliency; context and 3D scenes; motion and 3D scene analysis; and poster sessions.

Variational Methods

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110430398
Total Pages : 540 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Variational Methods by : Maïtine Bergounioux

Download or read book Variational Methods written by Maïtine Bergounioux and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-01-11 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on the interplay between mathematics and applications of imaging, the first part covers topics from optimization, inverse problems and shape spaces to computer vision and computational anatomy. The second part is geared towards geometric control and related topics, including Riemannian geometry, celestial mechanics and quantum control. Contents: Part I Second-order decomposition model for image processing: numerical experimentation Optimizing spatial and tonal data for PDE-based inpainting Image registration using phase・amplitude separation Rotation invariance in exemplar-based image inpainting Convective regularization for optical flow A variational method for quantitative photoacoustic tomography with piecewise constant coefficients On optical flow models for variational motion estimation Bilevel approaches for learning of variational imaging models Part II Non-degenerate forms of the generalized Euler・Lagrange condition for state-constrained optimal control problems The Purcell three-link swimmer: some geometric and numerical aspects related to periodic optimal controls Controllability of Keplerian motion with low-thrust control systems Higher variational equation techniques for the integrability of homogeneous potentials Introduction to KAM theory with a view to celestial mechanics Invariants of contact sub-pseudo-Riemannian structures and Einstein・Weyl geometry Time-optimal control for a perturbed Brockett integrator Twist maps and Arnold diffusion for diffeomorphisms A Hamiltonian approach to sufficiency in optimal control with minimal regularity conditions: Part I Index

Modeling in Computational Biology and Biomedicine

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Publisher : Springer Science & Business Media
ISBN 13 : 364231208X
Total Pages : 333 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Modeling in Computational Biology and Biomedicine by : Frédéric Cazals

Download or read book Modeling in Computational Biology and Biomedicine written by Frédéric Cazals and published by Springer Science & Business Media. This book was released on 2012-11-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational biology, mathematical biology, biology and biomedicine are currently undergoing spectacular progresses due to a synergy between technological advances and inputs from physics, chemistry, mathematics, statistics and computer science. The goal of this book is to evidence this synergy by describing selected developments in the following fields: bioinformatics, biomedicine and neuroscience. This work is unique in two respects - first, by the variety and scales of systems studied and second, by its presentation: Each chapter provides the biological or medical context, follows up with mathematical or algorithmic developments triggered by a specific problem and concludes with one or two success stories, namely new insights gained thanks to these methodological developments. It also highlights some unsolved and outstanding theoretical questions, with a potentially high impact on these disciplines. Two communities will be particularly interested in this book. The first one is the vast community of applied mathematicians and computer scientists, whose interests should be captured by the added value generated by the application of advanced concepts and algorithms to challenging biological or medical problems. The second is the equally vast community of biologists. Whether scientists or engineers, they will find in this book a clear and self-contained account of concepts and techniques from mathematics and computer science, together with success stories on their favorite systems. The variety of systems described represents a panoply of complementary conceptual tools. On a practical level, the resources listed at the end of each chapter (databases, software) offer invaluable support for getting started on a specific topic in the fields of biomedicine, bioinformatics and neuroscience.