Drug Resistance and Selectivity: Biochemical and Cellular Basis

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Publisher :
ISBN 13 :
Total Pages : 554 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Drug Resistance and Selectivity: Biochemical and Cellular Basis by : Enrico Mihich

Download or read book Drug Resistance and Selectivity: Biochemical and Cellular Basis written by Enrico Mihich and published by . This book was released on 1973 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Journal of the National Cancer Institute

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ISBN 13 :
Total Pages : 1058 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Journal of the National Cancer Institute by :

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1997 with total page 1058 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antitumor Drug Resistance

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Publisher : Springer Science & Business Media
ISBN 13 : 364269490X
Total Pages : 742 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Antitumor Drug Resistance by : Brian W. Fox

Download or read book Antitumor Drug Resistance written by Brian W. Fox and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published since then reporting development of resistance to most of the well-known anticancer agents in many different animal tumour systems, both in vivo and in vitro. Many different mechanisms of resistance have been described, and it is clear that the tumour cell has a wide diversity of options in overcoming the cell-killing activity of these agents. Definition of the magnitude of the phenomenon in the clinic is, however, much more problematical, and it is with this in mind that the initial chapter, seeks to out line the problem as the clinicians see it. It appears that the phenomenon of true resistance to a drug, as the biochemist would recognise it, is an important cause of the failure which clinicians experience in treating the disease. The extent of the contribution of this phenomenon to the failure of treatment cannot easily be evaluated at the present time, but it is hoped that the development and application of new and more sophisticated techniques for the analysis of cellular sub populations may help to give a more exact estimate and to shed some light on the causes of failure of many of the present therapeutic techniques.

Journal

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ISBN 13 :
Total Pages : 1084 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Journal by : National Cancer Institute (U.S.)

Download or read book Journal written by National Cancer Institute (U.S.) and published by . This book was released on 1977 with total page 1084 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Treatment Reports

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ISBN 13 :
Total Pages : 606 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cancer Treatment Reports by :

Download or read book Cancer Treatment Reports written by and published by . This book was released on 1984 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anthracycline Antibiotics in Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 9400976305
Total Pages : 580 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Anthracycline Antibiotics in Cancer Therapy by : Franco M. Muggia

Download or read book Anthracycline Antibiotics in Cancer Therapy written by Franco M. Muggia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: F. M. MUGGIA When faced with the inadequacies of current cancer treatment, we prefer to look at what the future may hold. Quite often, we take for granted the past, preferring research into totally new areas. However, the persistent development of fertile soil may yield surprising rewards for those who choose to build on the knowledge of the past--hence, this symposium on anthracycline antibiotics. Although the anthracycline antibiotics represent much of the present and future of cancer treatment, their actual use c stretches back barely two decades to the pioneering efforts of Aurelio Di Marco, who characterized the antitumor properties of daunomycin and adriamycin. * The clinical application of these two compounds heralded a decade of excitement among oncologists dealing with pediatric tumors, breast cancer, leukemias, and lymphomas, and opened new hope for patients afflicted with sar comas and a variety of other tumors that had been deemed - sistant to chemotherapy. These successes were tempered with the realization that the antitumor effect of anthracyclines could be achieved at times only at the very high price of risking cardiac decompensation and, almost invariably, with the occurrence of alopecia and other acute toxicities. This record of past achievements and problems has slowly given way to a present increasingly illuminated by our ability to modify the distressing toxicities of these agents. Detailed clinical studies supplemented by ingenious laboratory models have gradually elucidated mechanisms and risk factors im plicated in the cardiomyopathy.

Drug Design

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Publisher : Elsevier
ISBN 13 : 1483216071
Total Pages : 375 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Drug Design by : E. J. Ariëns

Download or read book Drug Design written by E. J. Ariëns and published by Elsevier. This book was released on 2013-10-22 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the utilization of operational schemes for analog synthesis in drug design; the design of enzyme inhibitors (transition state analogs); and the significance of structure-absorption-distribution relationships for drug design. The text describes the role of charge-transfer processes in the action of bioactive materials, as well as the approaches to the rational combination of antimetabolites for cancer chemotherapy. The physicochemical, quantum chemical, and other theoretical techniques for the understanding of the mechanism of action of central nervous system (CNS) agents, such as psychoactive drugs, narcotics, and narcotic antagonists and anesthetics, are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

Beyond the Molecular Frontier

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Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Medical Research in the Veteran's Administration

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ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Research in the Veteran's Administration by : United States. Veterans Administration

Download or read book Medical Research in the Veteran's Administration written by United States. Veterans Administration and published by . This book was released on 1976 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds

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Publisher : National Academies Press
ISBN 13 : 0309030447
Total Pages : 393 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds by : National Research Council

Download or read book The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds written by National Research Council and published by National Academies Press. This book was released on 1980-02-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Chemotherapy Reports

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Publisher :
ISBN 13 :
Total Pages : 1154 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer Chemotherapy Reports by :

Download or read book Cancer Chemotherapy Reports written by and published by . This book was released on 1973 with total page 1154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drugs and Immune Responsiveness

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Publisher : Springer
ISBN 13 : 1349046361
Total Pages : 258 pages
Book Rating : 4.3/5 (49 download)

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Book Synopsis Drugs and Immune Responsiveness by : J.L. Turk

Download or read book Drugs and Immune Responsiveness written by J.L. Turk and published by Springer. This book was released on 1979-06-17 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Responses in Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1468412361
Total Pages : 267 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biological Responses in Cancer by : Enrico Mihich

Download or read book Biological Responses in Cancer written by Enrico Mihich and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series of volumes entitled Biological Responses in Cancer provides information on approaches through which the interaction between neoplas tic and normal cells may be modified. Topics discussed in various volumes include immunological and host defense systems, control mechanisms of cell and population growth, cell differentiation, and cell transformation. This volume is specifically concerned with various aspects of cell interactions and regulation within heterogeneous tumor cell populations, and their role in tumor progression and metastasis. Knowledge in this area is likely to provide new leads toward the exploitation of novel cellular sites and mech anisms in the development of new types of therapies of cancer. Several topics are discussed within these general areas of consideration. The possibly unique characteristics and mechanisms of tumor vascularization and the potential sites of interference with angiogenesis that might have therapeutic impli cations are critically evaluated. Tumor cell-normal tissue interactions in volved in different phases of the growth and metastatic processes are dis cussed in two chapters dealing with mechanisms of tumor invasion and with the role of collagen in mammary tumor growth; here again potential leads are identified that may be exploited toward the development of new thera peutic approaches. The evolution of phenotypic diversity as a phenomenon complicating the biology of tumor metastasis and consequently affecting the opportunities offered by chemotherapy is also critically considered.

National Library of Medicine Current Catalog

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ISBN 13 :
Total Pages : 1256 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1973 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

The Chemotherapy Source Book

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Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 1552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Chemotherapy Source Book by : Michael Clinton Perry

Download or read book The Chemotherapy Source Book written by Michael Clinton Perry and published by Lippincott Williams & Wilkins. This book was released on 1996 with total page 1552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The updated Third Edition of The Chemotherapy Source Book is the most current and comprehensive reference on cancer chemotherapy. It brings together pharmacologic and patient management information in one source that practitioners can consult for any question encountered in the delivery of chemotherapy. This edition features increased information on the expanding use of high-dose therapy for various cancers, including breast cancer, leukemias, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphoma, lung cancer, and ovarian cancer. Coverage also includes new material on monoclonal antibodies, monoclonal antibody therapy, and breast, colon, and lung cancers, and information on five new drugs approved since the Second Edition. A Brandon-Hill recommended title.

Advances in Applied Microbiology

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Publisher : Academic Press
ISBN 13 : 0080564305
Total Pages : 365 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Applied Microbiology by :

Download or read book Advances in Applied Microbiology written by and published by Academic Press. This book was released on 1974-02-08 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays.