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Dinitrosyl Iron Complexes As A Working Form Of Nitric Oxide In Living Organisms
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Book Synopsis Dinitrosyl Iron Complexes as a “Working Form” of Nitric Oxide in Living Organisms by : Anatoly F. Vanin
Download or read book Dinitrosyl Iron Complexes as a “Working Form” of Nitric Oxide in Living Organisms written by Anatoly F. Vanin and published by Cambridge Scholars Publishing. This book was released on 2019-09-30 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sums up the results of more than 50 years’ work on the physico-chemical characteristics and biological activities of dinitrosyl iron complexes (DNIC). The interest of researchers in DNIC increased dramatically after the discovery of the fundamental role of the DNIC constituent nitrogen monoxide (NO) as one of the most universal regulators of metabolic processes occurring in living organisms. By virtue of their ability to donate NO and nitrosonium ions (NO+), DNIC mimic their beneficial (regulatory) and detrimental (cytotoxic) effects on living organisms and represent their “working” form. This text will appeal to practitioners in the field of biology, and other areas of modern-day science.
Book Synopsis Dinitrosyl Iron Complexes as a  Oeworking Formâ Of Nitric Oxide in Living Organisms by : ANATOLY F. VANIN
Download or read book Dinitrosyl Iron Complexes as a  Oeworking Formâ Of Nitric Oxide in Living Organisms written by ANATOLY F. VANIN and published by Cambridge Scholars Publishing. This book was released on 2019-11 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sums up the results of more than 50 yearsâ (TM) work on the physico-chemical characteristics and biological activities of dinitrosyl iron complexes (DNIC). The interest of researchers in DNIC increased dramatically after the discovery of the fundamental role of the DNIC constituent nitrogen monoxide (NO) as one of the most universal regulators of metabolic processes occurring in living organisms. By virtue of their ability to donate NO and nitrosonium ions (NO+), DNIC mimic their beneficial (regulatory) and detrimental (cytotoxic) effects on living organisms and represent their â oeworkingâ form. This text will appeal to practitioners in the field of biology, and other areas of modern-day science.
Book Synopsis Radicals for Life by : Ernst van Faassen
Download or read book Radicals for Life written by Ernst van Faassen and published by Elsevier. This book was released on 2011-10-13 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included. First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes Extensive bibliographic references, written by specialists of human physiology Providing high scientific quality with a focus on implications for human diseases
Book Synopsis Reactions of S-nitrosothiols with Biomimetic Iron Complexes and Other Transition Metals by : Eric Victor (Ph. D.)
Download or read book Reactions of S-nitrosothiols with Biomimetic Iron Complexes and Other Transition Metals written by Eric Victor (Ph. D.) and published by . This book was released on 2014 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 1. Bioinorganic Chemistry of Nitric Oxide and S-Nitrosothiols The interplay of nitric oxide (NO), biological thiols, and metals has been a topic of intense study since the discovery of NO as the endothelium-derived relaxation factor. NO is a redox-active diatomic, radical gas that is generated biologically during the conversion of L-arginine to L-citrulline by nitric oxide synthases (NOS), NADH, and 02. NOS enzymes have ironporphyrin and biopterin cofactors that catalyze this conversion. S-nitrosothiols form in biology as NO-transport mechanisms, post-translational modifications, or as a cellular protectant against overexposure to NO. Heme and non-heme iron cofactors serve as targets in biology to induce degradation of active sites or to induce conformational changes to inhibit or promote cellular pathways. The only structurally characterized metal complexes containing S-nitrosothiols have either iridium or ruthenium centers. Chapter 2. Rapid Nitric Oxide and Nitrogen Dioxide Detection and Quantification Assays and Devices based on M(BIPhMe)X2 Complexes To explore the release of nitrogen oxide gases from reaction solutions, we developed a series of colorimetric sensors based on the cis-nitrogen donating ligand BIPhMe, bis-(1-methylimidazol-2-yl)phenylmethoxymethane. The complexes M(BIPhMe)X2, where M is Fe2+ or Co2+ and X is Cl~, Br, or I, were prepared, and structurally and spectroscopically characterized. The reactivity of these complexes toward NO (g) and NO2 (g) in solution was explored and characterized. These complexes were then incorporated into test strips and syringes to provide devices that can qualitatively, and in the case of the syringes quantitatively, detect NO(g) and NO2(g) in a reaction headspace without additional equipment. Chapter 3. Reactions of (PPN)(SNO) and (PPN)(SSNO) with HBF4 and Biomimetic Iron Complexes. The biological relevance of HSNO as a transnitrosating was recently reported. The gas H2S can perform an H+-NO+ exchange with an S-nitrosated serum albumin to form HSNO, which can cross the cellular membrane and transnitrosate an exposed cysteine on a hemoglobin protein. With this discovery, we explored the reactivity of the anion SNO- and the related SSNO- toward an acid and the biomimetic iron complexes [FeIII(TPP)Cl], [Fe2S2(SPh)4]2-, [Fe2(Et-HPTB)(PhCO2)]2+, [Fe2([mu]-OH)(Ph4DBA)(TMEDA)2(OTf)], and [Fe(BIPhMe)Cl2]. In all cases HSNO was found to be unstable. The reaction of SNO with HBF4 led to NO (g) release. The reaction of both S-nitrosothiols with [FeIIITPP)Cl] resulted in reductive nitrosylation of the iron center. The reaction of the [2Fe-2S] cluster with both S-nitrosothiols led to the formation of reduced Roussin's black anion. The reaction of the mononuclear complex [Fe(BLPhMe)C12] with both S-nitrosothiols led to formation of the dinitrosyl iron complex [FeS5(NO)2]-. Only with the two diiron complexes was a difference in reactivity between SNO and SSNO- observed, leading to formation of Roussin's black anion or [FeS5(NO)2]-, respectively. Chapter 4. Reactions of Nitrogen Oxide Species with a Monofunctional Platinum Complex The structural isomers SNO- and NSO- have both been synthetically prepared, but only the metal-binding reactivity of NSO has been previously explored. Structural characterization of early first-row, and second and third row transition metals are reported with NSO-, where metal-binding occurs via the terminal nitrogen atom. We attempted to form structurally characterizable Pt-SNO and Pt-SSNO complexes using the "monofunctional" complex cis-[Pt(NH3)2(py)Cl](OTf), but were not successful. Instead, a new complex formed that we propose to be a polysulfide-bridged diplatinum complex with intact nitrogen-binding of the starting complex and release of NO (g). The vibrational spectra of the proposed complexes were calculated using DFT methods to compare with the experimental data and provides further evidence for the formation of a polysulfide-bridged diplatinum complex. DFT calculations were also performed on possible structural isomers of Pt-SNO and Pt-SSNO complexes. To test whether that the reactivity may not occur by release of NO+ from the S-nitrosothiols, cis-[Pt(NH3)2(py)Cl](OTf) was found to react with NOBF4 to form cis-[Pt(NH3)2(py)(CH3CN)]2+ and cis-mer-[Pt(NH3)2(py)Cl3]+. Chapter 5. Synthesis of [3:1] Site-Differentiated [4Fe-4S] Clusters and their Reactivity towards NO (g) and Ph3CSNO Previous studies provide evidence that [4Fe-4S] clusters serve as targets of reactive nitrogen oxide species in biology. The products of this reaction range from dinitrosyl iron complexes, [Fe(NO)2L2]-, to Roussin's Black Anion, [Fe4S3(NO)7] . To date, the pathways by which these reactions occur have not been fully elucidated. In this study we prepared the site-differentiated complexes [Fe4S4(LS3)L']2 - (LS3 = 1,3,5-tris(4,6-dimethyl-3-mercaptophenylthio)-2,4,6- tris(p-tolylthio)benzene; L' = Cl, SEt, SPh, N3, 2-SPyr, Tp, S2CNEt2) to serve as synthetic models for biological [4Fe-4S] clusters and studied their reactivity toward NO (g) and Ph3CSNO. The products were characterized by X-ray crystallography, mass spectrometry, and IR, EPR, and H NMR spectroscopy. In all cases reported here, the reactions proceed via formation of the S = V2 species [Fe4S4(NO)4 ] , which ultimately converts to EPR-silent [Fe4 S3(NO)7]. Appendix A. M(BIPhMe) Complexes and Reactions with RNOS The synthesis and characterization of the metal-BIPhMe complexes [Fe(BIPhMe)I2], [Fe(BIPhMe)(MeCN)2(OTf)2], [Fe2([mu]-O)(BIPhMe)2(NO3)4], [Cu(BIPhMe)2](OTf)2 [Cu(BIPhMe)2][CuCl2], and [Zn2([mu]-OTf)2(BIPhMe)2(OTf)2] was reported. These complexes were characterized by X-ray diffraction, FTIR, 1H NMR, and ESI-MS. The reaction of [Zn2([mu]-OTf)2(BIPhMe)2(OTf)2] with (PPN)(SNO) results in the release of NO (g) and formation of (PPN)(SSNO) and a zinc-sulfide species. The reaction of (PPN)(SSNO) results in the release of NO (g) and a zinc-sulfide species. Appendix B. Mass-Spec and FTIR figures of the Reactions of NO (g) and Ph3CSNO with [Fe4S4(LS3)L']2-
Book Synopsis Bioinspired Synthesis and Reactivity Studies of Nitric Oxide Iron Complexes by : Jennifer Hess
Download or read book Bioinspired Synthesis and Reactivity Studies of Nitric Oxide Iron Complexes written by Jennifer Hess and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The significant role that nitric oxide plays in human physiology is linked to the ability of NO to bind to iron forming mono-nitrosyl iron complexes. Protein-bound and low-molecular-weight dinitrosyl iron complexes (DNICs) are known to form in excess NO. Studies of such biological DNICs have relied on their paramagnetism and characteristic EPR signal of g value of 2.03. It has been suggested that DNICs act in vivo as NO storage (when protein-bound) and transfer agents (when released by, for example, free cysteine). Biological DNICs, mainly resulting from iron-sulfur cluster degradation, are difficult to extract and isolate, thereby preventing their full characterization. Thus, development of synthetic DNICs is a promising approach to model and better understand the formation and function of biological DNICs, the scope of donor ligands that might coexist with Fe(NO)2 units, the redox levels of bio-DNICs, and establish other spectroscopic techniques appropriate for characterization. A series of N-heterocyclic carbene (NHC) and imidazole (Imid) complexes has been characterized as mimics of histidine-containing DNICs. The pseudo-tetrahedral L2Fe(NO)2 complexes have NO stretching frequencies and redox potentials that suggest the NHCs are slightly better donors than Imids, however the two types of ligands have similar steric properties. Both the EPR-active, {Fe(NO)2}9 and the EPR-silent, {Fe(NO)2}10 states can be accessed and stabilized by the NHC. Nitric oxide transfer studies have shown that only the {Fe(NO)2}9 complexes are capable of transferring NO to a suitable NO trapping agent. Deprotonation of the distal nitrogen functionality in the imidazolate ligands of [(Imidazole)2Fe(NO)2]- leads to aggregation forming molecular squares of {Fe(NO)2}9 units bridged by the imidazolates. These interesting tetrameric complexes are examined by X-ray diffraction, EPR, and Mössbauer studies. The paramagnetic tetrameric complexes have multiple redox events observed by cyclic voltammetry. Mössbauer spectral data of the tetrameric complexes are compared with Mössbauer data obtained for a series of NHC-containing DNICs. Iron and cobalt-containing mononitrosyl N2S2 model complexes of the nitrile hydratase enzyme active site demonstrate sulfur-based reactivity resulting in the formation of polymetallic complexes. In all cases, shifts in the nitrosyl stretching frequencies demonstrate substantial transfer of electron density from the (NO)M(N2S2) moiety to the metal-acceptor site.
Book Synopsis Measuring Oxidants and Oxidative Stress in Biological Systems by : Lawrence J. Berliner
Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
Book Synopsis Nitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine I by : D. Michael P. Mingos
Download or read book Nitrosyl Complexes in Inorganic Chemistry, Biochemistry and Medicine I written by D. Michael P. Mingos and published by Springer. This book was released on 2014-06-05 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.
Book Synopsis Nitrosation Reactions and the Chemistry of Nitric Oxide by : D.L.H. Williams
Download or read book Nitrosation Reactions and the Chemistry of Nitric Oxide written by D.L.H. Williams and published by Elsevier. This book was released on 2004-12-16 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990. * Provides an update on previously published literature on nitric oxide chemistry* Contains chapters on reagents for nitrosation, nitrosation at nitrogen, aliphatic and aromatic carbon, oxygen, sulfur and metal centres* Looks at hot research topics such as synthesis, properties and reactions of s-nitrosothiols
Book Synopsis Modulation of Oxidative Stress by : Luciano Saso
Download or read book Modulation of Oxidative Stress written by Luciano Saso and published by Elsevier. This book was released on 2023-08-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer’s disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and includes chapters on phytotherapy and flavonoids. This book is a strong reference for pharma researchers in academia and industry considering leveraging modulation of oxidative stress as a strategy for the development of new drugs. Biochemists and Nutritionists may also benefit of the foundational understanding of cellular redox processes laid out. Provides the latest updates in the fast-developing field of REDOX biochemistry and pharmacology Presents content that is clear and easy to read Useful for researchers and instructors in many fields
Book Synopsis Nitric Oxide in Transplant Rejection and Anti-Tumor Defense by : Stanislaw Lukiewicz
Download or read book Nitric Oxide in Transplant Rejection and Anti-Tumor Defense written by Stanislaw Lukiewicz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric Oxide in Transplant Rejection and Anti-Tumor Defense represents a unique combination of three interrelated topics that is unavailable in any other single work: The detection and visualization of nitric oxide in biological materials using EPR spectroscopy and EPR imaging; Nitric oxide in immune mechanisms of allograft rejection; and The involvement of nitric oxide in anti-tumor defense. By bringing together specialists from these three disciplines, the book investigates the common molecular and cellular mechanisms underlying phenomena in transplants and oncology. In addition, the book provides an introduction to biological applications of EPR spectroscopy and imaging. Nitric Oxide in Transplant Rejection and Anti-Tumor Defense will appeal to researchers and graduate-level students investigating transplant rejections and their immune mechanisms, anti-tumor immune defenses, novel types of contrast agents for EPR imaging, and biological applications of EPR spectroscopy and EPR imaging.
Book Synopsis In Vivo EPR (ESR) by : Lawrence J. Berliner
Download or read book In Vivo EPR (ESR) written by Lawrence J. Berliner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Vivo EPR (ESR) is a textbook on this relatively new subject in biomedical electron spin resonance. While a few chapters have appeared in special topics volumes in this series, this book covers the principles and theory, instrumentation as well as the latest applications at the time of its writing. The authors are world-renowned experts and pioneers in their fields. This book is divided into two major sections dealing with theory and instrumentation, and aspects of biochemistry, in vitro and in vivo applications. A significant amount of detail is devoted to clinical applications and the problems and pitfalls encountered in in vivo spectroscopy and imaging. Key Features: -History of In Vivo EPR, -Principles of Imaging-Theory and Instrumentation, -Time-domain Radio Frequency EPR Imaging, -The Measurement of Oxygen In Vivo Using In Vivo EPR Techniques, -Potential Medical (Clinical) Applications of EPR, -Combining NMR and EPR/ESR for In Vivo Experiments.
Download or read book Nitric Oxide written by Lester Packer and published by Gulf Professional Publishing. This book was released on 1999 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: General Description of the Volume: Nitric Oxide, recently designated "Molecule of the Year," impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume will be a valuable resource for the experienced researcher as well as for those newly entering the field. This volume continues the coverage of new and important tools for the elucidation of Nitric Oxide action initiated in Volumes 268 and 269 of Methods in Enzymology. Techniques for researching the physiology and toxicity of nitric oxide in cellular and organismal systems are highlighted. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Biological Activity * NO Donors: Nitrosothiols and Nitroxyls * Peroxynitrite * Oxidant and Antioxidant Action.
Book Synopsis Progress in Inorganic Chemistry, Volume 59 by : Kenneth D. Karlin
Download or read book Progress in Inorganic Chemistry, Volume 59 written by Kenneth D. Karlin and published by John Wiley & Sons. This book was released on 2014-07-28 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 59 continues to report recent advances with a significant, up-to-date selection of contributions by internationally-recognized researchers. The chapters of this volume are devoted to the following topics: • Iron Catalysis in Synthetic Chemistry • A New Paradigm for Photodynamic Therapy Drug Design: Multifunctional, Supramolecular DNA Photomodification Agents Featuring Ru(II)/Os(II) Light Absorbers Coupled to Pt(II) or Rh(III) Bioactive Sites • Selective Binding of Zn2+ Complexes to Non-Canonical Thymine or Uracil in DNA or RNA. • Progress Toward the Electrocatalytic Production of Liquid Fuels from Carbon Dioxide • Monomeric Dinitrosyl Iron Complexes: Synthesis and Reactivity • Interactions of Nitrosoalkanes/arenes, Nitrosamines, Nitrosothiols, and Alkyl Nitrites with Metals • Aminopyridine Iron and Manganese Complexes as Molecular Catalysts for Challenging Oxidative Transformations
Book Synopsis Reactive Oxygen, Nitrogen and Sulfur Species in Plants by : Mirza Hasanuzzaman
Download or read book Reactive Oxygen, Nitrogen and Sulfur Species in Plants written by Mirza Hasanuzzaman and published by John Wiley & Sons. This book was released on 2019-07-02 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a multidisciplinary analysis of the integration among reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS). Since plants are the main source of our food, the improvement of their productivity is the most important task for plant biologists. In this book, leading experts accumulate the recent development in the research on oxidative stress and approaches to enhance antioxidant defense system in crop plants. They discuss both the plant responses to oxidative stress and mechanisms of abiotic stress tolerance, and cover all of the recent approaches towards understanding oxidative stress in plants, providing comprehensive information about the topics. It also discusses how reactive nitrogen species and reactive sulfur species regulate plant physiology and plant tolerance to environmental stresses. Reactive Oxygen, Nitrogen and Sulfur Species in Plants: Production, Metabolism, Signaling and Defense Mechanisms covers everything readers need to know in four comprehensive sections. It starts by looking at reactive oxygen species metabolism and antioxidant defense. Next, it covers reactive nitrogen species metabolism and signaling before going on to reactive sulfur species metabolism and signaling. The book finishes with a section that looks at crosstalk among reactive oxygen, nitrogen, and sulfur species based on current research done by experts. Presents the newest method for understanding oxidative stress in plants. Covers both the plant responses to oxidative stress and mechanisms of abiotic stress tolerance Details the integration among reactive oxygen species (ROS), reactive nitrogen species (RNS) and reactive sulfur species (RSS) Written by 140 experts in the field of plant stress physiology, crop improvement, and genetic engineering Providing a comprehensive collection of up-to-date knowledge spanning from biosynthesis and metabolism to signaling pathways implicated in the involvement of RONSS to plant defense mechanisms, Reactive Oxygen, Nitrogen and Sulfur Species in Plants: Production, Metabolism, Signaling and Defense Mechanisms is an excellent book for plant breeders, molecular biologists, and plant physiologists, as well as a guide for students in the field of Plant Science.
Book Synopsis Biological Inorganic Chemistry by : Ivano Bertini
Download or read book Biological Inorganic Chemistry written by Ivano Bertini and published by University Science Books. This book was released on 2007 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.
Book Synopsis Abiotic Stress Signaling in Plants: Functional Genomic Intervention by : Girdhar K. Pandey
Download or read book Abiotic Stress Signaling in Plants: Functional Genomic Intervention written by Girdhar K. Pandey and published by Frontiers Media SA. This book was released on 2016-08-08 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abiotic stresses such as high temperature, low-temperature, drought and salinity limit crop productivity worldwide. Understanding plant responses to these stresses is essential for rational engineering of crop plants. In Arabidopsis, the signal transduction pathways for abiotic stresses, light, several phytohormones and pathogenesis have been elucidated. A significant portion of plant genomes (Arabidopsis and rice were mostly studied) encodes for proteins involves in signaling such as receptor, sensors, kinases, phosphatases, transcription factors and transporters/channels. Despite decades of physiological and molecular effort, knowledge pertaining to how plants sense and transduce low and high temperature, low-water availability (drought), water-submergence, microgravity and salinity signals is still a major question for plant biologist. One major constraint hampering our understanding of these signal transduction processes in plants has been the lack or slow pace of application of molecular genomic and genetics knowledge in the form of gene function. In the post-genomic era, one of the major challenges is investigation and understanding of multiple genes and gene families regulating a particular physiological and developmental aspect of plant life cycle. One of the important physiological processes is regulation of stress response, which leads to adaptation or adjustment in response to adverse stimuli. With the holistic understanding of the signaling pathways involving not only one gene family but multiple genes or gene families, plant biologist can lay a foundation for designing and generating future crops, which can withstand the higher degree of environmental stresses (especially abiotic stresses, which are the major cause of crop loss throughout the world) without losing crop yield and productivity. Therefore, in this e-Book, we intend to incorporate the contribution from leading plant biologists to elucidate several aspects of stress signaling by functional genomics approaches.
Book Synopsis Bioinorganic Photochemistry by : Grazyna Stochel
Download or read book Bioinorganic Photochemistry written by Grazyna Stochel and published by John Wiley & Sons. This book was released on 2009-06-10 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.
