Radicals for Life

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Publisher : Elsevier
ISBN 13 : 9780080489599
Total Pages : 442 pages
Book Rating : 4.4/5 (895 download)

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Book Synopsis Radicals for Life by : Ernst van Faassen

Download or read book Radicals for Life written by Ernst van Faassen and published by Elsevier. This book was released on 2011-10-13 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included. First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes Extensive bibliographic references, written by specialists of human physiology Providing high scientific quality with a focus on implications for human diseases

Free Radicals in Biology and Medicine

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Publisher : Oxford University Press
ISBN 13 : 0198717474
Total Pages : 961 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell

Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by Oxford University Press. This book was released on 2015 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Free Radicals in Exercise and Aging

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Author :
Publisher : Human Kinetics
ISBN 13 : 9780880118811
Total Pages : 286 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Free Radicals in Exercise and Aging by : Zsolt Radák

Download or read book Free Radicals in Exercise and Aging written by Zsolt Radák and published by Human Kinetics. This book was released on 2000 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the emerging field of free radical biology, exercise, and aging with this definitive reference. Free Radicals in Exercise and Agingaddresses the current debate regarding whether free radicals released during exercise accelerate the aging process. It explains how free radicals can serve as important regulators of aerobic processes, and it clarifies the importance of exercise in increasing the efficiency of the antioxidant and oxidative repair systems. Mounting research data indicate that free radicals are involved in a variety of physiological and pathophysiological processes. This book focuses on exercise-induced adaptation. In general, a person's ability to adapt to internal and external changes decreases during the aging process. However, by continually exposing the body to different challenges, regular exercise triggers an adaptation process that keeps the body and mind fit. Free Radicals in Exercise and Agingelucidates the role of free radical species in regulating this process. This text is also one of the first to provide an in-depth review of skeletal muscle oxidative stress and aging. This issue is pivotal because muscle serves such a critical role in mobility and normal life. Free Radicals in Exercise and Aging shares the most current understanding of how reactive oxygen species influence the biology of skeletal muscles. It explores some of the unique characteristics that skeletal muscle displays during aging, both in terms of free radical production and with regard to antioxidant systems. The implications of this research are far-reaching. Mutation of DNA is linked very closely to cancer, and if regular exercise improves the regulation of the antioxidant systems and the oxidative damage repair system, these mechanisms may be a very important tool against this deadly disease. This research-oriented text presents the latest information on the subject. It reviews and critiques current literature and provides critical information for exercise physiologists, sports medicine specialists, sport nutritionists, and gerontologists.

Radical Technologies

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Publisher : Verso Books
ISBN 13 : 1784780472
Total Pages : 368 pages
Book Rating : 4.7/5 (847 download)

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Book Synopsis Radical Technologies by : Adam Greenfield

Download or read book Radical Technologies written by Adam Greenfield and published by Verso Books. This book was released on 2017-06-13 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A field manual to the technologies that are transforming our lives Everywhere we turn, a startling new device promises to transfigure our lives. But at what cost? In this urgent and revelatory excavation of our Information Age, leading technology thinker Adam Greenfield forces us to reconsider our relationship with the networked objects, services and spaces that define us. It is time to re-evaluate the Silicon Valley consensus determining the future. We already depend on the smartphone to navigate every aspect of our existence. We’re told that innovations—from augmented-reality interfaces and virtual assistants to autonomous delivery drones and self-driving cars—will make life easier, more convenient and more productive. 3D printing promises unprecedented control over the form and distribution of matter, while the blockchain stands to revolutionize everything from the recording and exchange of value to the way we organize the mundane realities of the day to day. And, all the while, fiendishly complex algorithms are operating quietly in the background, reshaping the economy, transforming the fundamental terms of our politics and even redefining what it means to be human. Having successfully colonized everyday life, these radical technologies are now conditioning the choices available to us in the years to come. How do they work? What challenges do they present to us, as individuals and societies? Who benefits from their adoption? In answering these questions, Greenfield’s timely guide clarifies the scale and nature of the crisis we now confront —and offers ways to reclaim our stake in the future.

Radicals

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Publisher : Simon and Schuster
ISBN 13 : 1621570061
Total Pages : 256 pages
Book Rating : 4.6/5 (215 download)

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Book Synopsis Radicals by : David Horowitz

Download or read book Radicals written by David Horowitz and published by Simon and Schuster. This book was released on 2012-09-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radical liberals want to make America a better place, but their utopian social engineering leads, ironically, to greater human suffering. So argues David Horowitz, bestselling author in his newest book Radicals: Portraits of a Destructive Passion. From Karl Marx to Barack Obama, Horowitz shows how the idealistic impulse to make the world “a better place” gives birth to the twin cultural pathologies of cynicism and nihilism, and is the chief source of human suffering. A former liberal himself, Horowitz recounts his own brushes with radicalism and offers unparalleled insight into the disjointed ideology of liberal elites through case studies of well-known radial leftists, including Christopher Hitchens, feminist Bettina Aptheker , leftist academic Cornel West, and more. Exploring the origin and evolution of radical liberals and their progressive ideology, Radicals illustrates how liberalism is not only intellectually crippling for its adherents, but devastating to society.

Rules for Radicals

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Author :
Publisher : Vintage
ISBN 13 : 0307756890
Total Pages : 226 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis Rules for Radicals by : Saul Alinsky

Download or read book Rules for Radicals written by Saul Alinsky and published by Vintage. This book was released on 2010-06-30 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This country's leading hell-raiser" (The Nation) shares his impassioned counsel to young radicals on how to effect constructive social change and know “the difference between being a realistic radical and being a rhetorical one.” First published in 1971 and written in the midst of radical political developments whose direction Alinsky was one of the first to question, this volume exhibits his style at its best. Like Thomas Paine before him, Alinsky was able to combine, both in his person and his writing, the intensity of political engagement with an absolute insistence on rational political discourse and adherence to the American democratic tradition.

Roots for Radicals

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Publisher : Bloomsbury Publishing
ISBN 13 : 1350043141
Total Pages : 176 pages
Book Rating : 4.3/5 (5 download)

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Book Synopsis Roots for Radicals by : Edward T. Chambers

Download or read book Roots for Radicals written by Edward T. Chambers and published by Bloomsbury Publishing. This book was released on 2018-01-25 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The successor to the legendary activist Saul Alinsky, Edward T. Chambers pioneered a set of principles and practices that have guided community organizations throughout the US and the world. Roots for Radicals remains his definitive reflection on these fundamental principles of community activism: how, as public citizens, we can navigate the gap between the world as it is and as it should be, between self-interest and self-sacrifice and in doing so create lasting change for our communities. In the face of the increasingly turbulent politics of the 21st-century, Chambers's book has never been more relevant.

Free Radicals

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Author :
Publisher : ABRAMS
ISBN 13 : 1468301713
Total Pages : 148 pages
Book Rating : 4.4/5 (683 download)

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Book Synopsis Free Radicals by : Michael Brooks

Download or read book Free Radicals written by Michael Brooks and published by ABRAMS. This book was released on 2012-04-26 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: “An exuberant tour through the world of scientists behaving badly” (The New York Times). They may have a public image as cool, logical, levelheaded types. But in reality, scientists will do pretty much anything—take drugs, follow mystical visions, lie, and even cheat—to make a discovery. In Free Radicals, physicist and journalist Michael Brooks seamlessly weaves together true stories of the “mad, bad and dangerous” men and women who have revolutionized the scientific world, and offers a fast-paced and thrilling exploration of the real process behind discovery (The Times, London). Brooks also traces the cover-up back to its source: the scientific establishment’s reaction to the public fear of science after World War II. He argues that it its high time for science to come clean about just how bold and daring scientists really are. “Not all scientists are nerds. In Free Radicals, physicist Michael Brooks tries to dispel the notion that scientists are stuffy, pen-protector-polishing bookworms.” —The Washington Post “Insightful . . . A page-turning, unvarnished look at the all-too-human side of science.” —Kirkus Reviews

Black Radical: The Life and Times of William Monroe Trotter

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Author :
Publisher : Liveright Publishing
ISBN 13 : 1631495356
Total Pages : 432 pages
Book Rating : 4.6/5 (314 download)

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Book Synopsis Black Radical: The Life and Times of William Monroe Trotter by : Kerri K. Greenidge

Download or read book Black Radical: The Life and Times of William Monroe Trotter written by Kerri K. Greenidge and published by Liveright Publishing. This book was released on 2019-11-19 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times • Times Critics Top Books of 2019 This long-overdue biography reestablishes William Monroe Trotter’s essential place next to Douglass, Du Bois, and King in the pantheon of American civil rights heroes. William Monroe Trotter (1872– 1934), though still virtually unknown to the wider public, was an unlikely American hero. With the stylistic verve of a newspaperman and the unwavering fearlessness of an emancipator, he galvanized black working- class citizens to wield their political power despite the violent racism of post- Reconstruction America. For more than thirty years, the Harvard-educated Trotter edited and published the Guardian, a weekly Boston newspaper that was read across the nation. Defining himself against the gradualist politics of Booker T. Washington and the elitism of W. E. B. Du Bois, Trotter advocated for a radical vision of black liberation that prefigured leaders such as Marcus Garvey, Malcolm X, and Martin Luther King Jr. Synthesizing years of archival research, historian Kerri Greenidge renders the drama of turn- of- the- century America and reclaims Trotter as a seminal figure, whose prophetic, yet ultimately tragic, life offers a link between the vision of Frederick Douglass and black radicalism in the modern era.

Radical Help

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Publisher : Virago
ISBN 13 : 0349009082
Total Pages : 320 pages
Book Rating : 4.3/5 (49 download)

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Book Synopsis Radical Help by : Hilary Cottam

Download or read book Radical Help written by Hilary Cottam and published by Virago. This book was released on 2018-06-07 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: How should we live: how should we care for one another; grow our capabilities to work, to learn, to love and fully realise our potential? This exciting and ambitious book shows how we can re-design the welfare state for this century. The welfare state was revolutionary: it lifted thousands out of poverty, provided decent homes, good education and security. But it is out of kilter now: an elaborate and expensive system of managing needs and risks. Today we face new challenges. Our resources have changed. Hilary Cottam takes us through five 'Experiments' to show us a new design. We start on a Swindon housing estate where families who have spent years revolving within our current welfare systems are supported to design their own way out. We spend time with young people who are helped to make new connections - with radical results. We turn to the question of good health care and then to the world of work and see what happens when people are given different tools to make change. Then we see those over sixty design a new and affordable system of support. At the heart of this way of working is human connection. Upending the current crisis of managing scarcity, we see instead that our capacities for the relationships that can make the changes are abundant. We must work with individuals, families and communities to grow the core capabilities we all need to flourish. Radical Help describes the principles behind the approach, the design process that makes the work possible and the challenges of transition. It is bold - and above all, practical. It is not a book of dreams. It is about concrete new ways of organising that already have been developing across Britain. Radical Help creates a new vision and a radically different approach that can take care of us once more, from cradle to grave.

Free Radicals in Human Health and Disease

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Author :
Publisher : Springer
ISBN 13 : 8132220358
Total Pages : 430 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Free Radicals in Human Health and Disease by : Vibha Rani

Download or read book Free Radicals in Human Health and Disease written by Vibha Rani and published by Springer. This book was released on 2014-11-14 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society. The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.

Free Radicals

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Publisher : IRL Press
ISBN 13 : 9780199635597
Total Pages : 310 pages
Book Rating : 4.6/5 (355 download)

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Book Synopsis Free Radicals by : Neville A. Punchard

Download or read book Free Radicals written by Neville A. Punchard and published by IRL Press. This book was released on 1996 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recognition that oxygen and nitrogen radicals are involved in normal cell metabolism, free radical research has begun to feature in most disciplines in the life sciences. Increasingly, their implication in a number of human disease processes is being accepted, altough conclusive evidence is lacking in many instances, partly due to the difficulties in detecting and measuring free radicals that have lifetimes measured in microseconds. This book outlines the latest techniques for quantifying radicals and their effects, and features detailed protocols, hints, and tips for success, troubleshooting comments, sample data, and key literature citations.

Oxygen Radicals in Biology and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1468455680
Total Pages : 1064 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Oxygen Radicals in Biology and Medicine by : Michael Simic

Download or read book Oxygen Radicals in Biology and Medicine written by Michael Simic and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.

American Radicals

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Publisher : Crown
ISBN 13 : 0525573097
Total Pages : 402 pages
Book Rating : 4.5/5 (255 download)

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Book Synopsis American Radicals by : Holly Jackson

Download or read book American Radicals written by Holly Jackson and published by Crown. This book was released on 2019-10-08 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dynamic, timely history of nineteenth-century activists—free-lovers and socialists, abolitionists and vigilantes—and the social revolution they sparked in the turbulent Civil War era “In the tradition of Howard Zinn’s people’s histories, American Radicals reveals a forgotten yet inspiring past.”—Megan Marshall, Pulitzer Prize–winning author of Margaret Fuller: A New American Life and Elizabeth Bishop: A Miracle for Breakfast NAMED ONE OF THE TEN BEST HISTORY BOOKS OF THE YEAR BY SMITHSONIAN On July 4, 1826, as Americans lit firecrackers to celebrate the country’s fiftieth birthday, both John Adams and Thomas Jefferson were on their deathbeds. They would leave behind a groundbreaking political system and a growing economy—as well as the glaring inequalities that had undermined the American experiment from its beginning. The young nation had outlived the men who made it, but could it survive intensifying divisions over the very meaning of the land of the free? A new network of dissent—connecting firebrands and agitators on pastoral communes, in urban mobs, and in genteel parlors across the nation—vowed to finish the revolution they claimed the founding fathers had only begun. They were men and women, black and white, fiercely devoted to causes that pitted them against mainstream America even while they fought to preserve the nation’s founding ideals: the brilliant heiress Frances Wright, whose shocking critiques of religion and the institution of marriage led to calls for her arrest; the radical Bostonian William Lloyd Garrison, whose commitment to nonviolence would be tested as the conflict over slavery pushed the nation to its breaking point; the Philadelphia businessman James Forten, who presided over the first mass political protest of free African Americans; Marx Lazarus, a vegan from Alabama whose calls for sexual liberation masked a dark secret; black nationalist Martin Delany, the would-be founding father of a West African colony who secretly supported John Brown’s treasonous raid on Harpers Ferry—only to ally himself with Southern Confederates after the Civil War. Though largely forgotten today, these figures were enormously influential in the pivotal period flanking the war, their lives and work entwined with reformers like Frederick Douglass, Elizabeth Cady Stanton, and Henry David Thoreau, as well as iconic leaders like Abraham Lincoln. Jackson writes them back into the story of the nation’s most formative and perilous era in all their heroism, outlandishness, and tragic shortcomings. The result is a surprising, panoramic work of narrative history, one that offers important lessons for our own time.

Systems Biology of Free Radicals and Antioxidants

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Author :
Publisher : Springer
ISBN 13 : 9783642300172
Total Pages : 0 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Systems Biology of Free Radicals and Antioxidants by : Ismail Laher

Download or read book Systems Biology of Free Radicals and Antioxidants written by Ismail Laher and published by Springer. This book was released on 2014-06-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.

Reveille for Radicals

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Author :
Publisher : Vintage
ISBN 13 : 0307756882
Total Pages : 257 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis Reveille for Radicals by : Saul Alinsky

Download or read book Reveille for Radicals written by Saul Alinsky and published by Vintage. This book was released on 2010-08-25 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legendary community organizer Saul Alinsky inspired a generation of activists and politicians with Reveille for Radicals, the original handbook for social change. Alinsky writes both practically and philosophically, never wavering from his belief that the American dream can only be achieved by an active democratic citizenship. First published in 1946 and updated in 1969 with a new introduction and afterword, this classic volume is a bold call to action that still resonates today.

Radical Hope

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Author :
Publisher : Harvard University Press
ISBN 13 : 0674040023
Total Pages : 200 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Radical Hope by : Jonathan Lear

Download or read book Radical Hope written by Jonathan Lear and published by Harvard University Press. This book was released on 2009-06-30 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the story of Plenty Coups, the last great Chief of the Crow Nation. This title contains a philosophical and ethical inquiry into a people faced with the end of their way of life.