Diagnostic Imaging for Pharmacists

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Publisher : American Pharmacists Association (APhA)
ISBN 13 : 9781582121536
Total Pages : 0 pages
Book Rating : 4.1/5 (215 download)

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Book Synopsis Diagnostic Imaging for Pharmacists by : Blaine T. Smith

Download or read book Diagnostic Imaging for Pharmacists written by Blaine T. Smith and published by American Pharmacists Association (APhA). This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients undergoing diagnostic imaging procedures may receive a variety of pharmaceutical interventional agents as part of the imaging procedure. Historically, these pharmaceutical agents have been overseen by the radiology department rather than the pharmacy department. With recent changes in regulatory oversight of medication management and with accreditation bodies increased emphasis on the subject, pharmacists are finding themselves in need of a better understanding of the policies, procedures, and use of pharmacologic agents in the diagnostic imaging arena.

Medical Imaging for Health Professionals

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Publisher :
ISBN 13 : 9781119537397
Total Pages : 503 pages
Book Rating : 4.5/5 (373 download)

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Book Synopsis Medical Imaging for Health Professionals by : Raymond Reilly

Download or read book Medical Imaging for Health Professionals written by Raymond Reilly and published by . This book was released on 2019 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book guides pharmacy and health researchers and professionals to understand and interpret medical imaging technology. Divided into two sections, coverage features both fundamental principles and clinical applications. It describes the most common imaging tools - X-ray, CT, ultrasound, MRI, SPECT, and PET - and their use to diagnose common diseases that include heart, cancer, and lung. In addition, the authors introduce the emerging role of molecular imaging in the management of cancer and selection of patients for personalized treatments. The book features many illustrations and provides patient case examples of imaging applications to diagnose disease or monitor therapy"--Provided by publisher.

Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine

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Publisher : American Pharmacists Association (APhA)
ISBN 13 :
Total Pages : 844 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine by : Richard J. Kowalsky

Download or read book Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine written by Richard J. Kowalsky and published by American Pharmacists Association (APhA). This book was released on 2004 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, 2nd edition," is an essential reference for nuclear pharmacy practitioners, nuclear medicine technologists, and nuclear medicine physicians. It will also be useful as a textbook in programs that educate these practitioners. The first 12 chapters cover radioactive decay, radiation detection and measurement, radiation protection and risk, radiation safety, radiation biology, licensing and regulatory controls, radionuclide production, radiopharmaceutical chemistry, radiopharmaceuticals for positron emission tomography (PET), the nuclear pharmacy, and quality control. Four of these chapters are written by contributing authors. Together the 12 chapters, all written by nuclear pharmacy practitioners, present the information needed for a pharmacist to become an authorized nuclear pharmacist. The remaining 11 chapters cover the diagnostic and therapeutic use of radiopharmaceuticals. Chapters on specific body systems (brain, thyroid, heart, lung, liver, spleen, gastrointestinal tract, kidney, and bone) are followed by chapters on total body procedures, monoclonal antibodies, in vivo function studies, and therapeutic radiopharmaceuticals. Key Features *Updates its predecessor, Radiopharmaceuticals in Nuclear Medicine Practice, to include new material in areas such as radiation biology, radiopharmaceuticals used in PET, and therapeutic radiopharmaceuticals. *Features expanded coverage of nuclear medicine applications of radiopharmaceuticals useful for nuclear pharmacy practitioners. *Some 150 tables and nearly 450 figures enrich and illustrate the text, and each chapter is referenced to the primary literature. About the Authors: Richard J. Kowalsky, PharmD, BCNP, FAPhA, is Associate Professor of Pharmacy, School of Pharmacy, and Associate Professor of Radiology, Department of Radiology, University of North Carolina at Chapel Hill. He is Director of the Nuclear Pharmacy at UNC Hospitals, where he has practiced for 32 years. Steven W. Falen, MD, PhD, is former Director of Positron Emission Tomography and Assistant Professor of Radiology and Biomedical Engineering, Department of Radiology, University of North Carolina at Chapel Hill. He is now Director of Nuclear Medicine and PET Services, Riverside Regional Medical Center, Newport News, Virginia.

Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine,

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Publisher : American Pharmacists Association (APhA)
ISBN 13 : 9781582122830
Total Pages : 800 pages
Book Rating : 4.1/5 (228 download)

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Book Synopsis Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, by : RICHARD J. KOWALSKY

Download or read book Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, written by RICHARD J. KOWALSKY and published by American Pharmacists Association (APhA). This book was released on 2020-03-10 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completed revised and updated, Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, 4th Edition is the radiopharmaceutical bible for nuclear pharmacists, nuclear medicine physicians, and nuclear medicine technologists. Useful in educational programs across these disciplines, it also serves as a key reference in preparation for specialty board examination in nuclear medicine and nuclear pharmacy. The book contains essential information required by state and federal radiation licensing organization for specialty practitioners preparing to become authorized nuclear pharmacists or authorized nuclear medicine physicians. Key Features: - All chapters are entirely reorganized and revised to reflect the latest developments in the field - Chapters new to the fourth edition cover of range of topics including Adverse Reactions to Radiopharmaceuticals, Pregnancy and Pediatrics, Localization Mechanisms of Radiopharmaceuticals, Non-Radioactive Pharmaceuticals, PET Manufacturing, and Radiopharmaceutical Distribution. - Over 500 figures and 200 tables--many in full-color--underscore key concepts

Medical Imaging in Clinical Trials

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Publisher : Springer Science & Business Media
ISBN 13 : 1848827105
Total Pages : 420 pages
Book Rating : 4.8/5 (488 download)

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Book Synopsis Medical Imaging in Clinical Trials by : Colin G. Miller

Download or read book Medical Imaging in Clinical Trials written by Colin G. Miller and published by Springer Science & Business Media. This book was released on 2014-01-30 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years the use of medical imaging has increased exponentially in routine clinical practice. This has been reflected in a rapidly increasing use of medical imaging in clinical trials, through all phases. More recently this has culminated in a number of inter-disciplinary meetings with the various stake holders, including the FDA. Changes in the regulatory process has resulted, when it comes to the submission of data to the FDA, in a therapeutic agent where one or more of the trial end-points is the assessment of a radiological end-point. No longer is it sufficient to have the images read by the local investigator site. The FDA has also identified Medical Imaging as one of the key 6 points in the Critical Path initiative which was launched in 2004. This puts a keen focus on the role of imaging and the need to clearly identify and understand this aspect of clinical trials. As the pharmaceutical, biotech and medical device industry continues to identify ways to improve and speed up product development, medical imaging plays a more significant role. An understanding of the methodology and the metrics is therefore required but difficult to ascertain in one easy to read volume for individuals entering this field. This book will therefore fulfill this void, be it for the pharmaceutical personnel from medical director to monitor, or the Principal Investigator who is having to understand the complexities of the imaging and why it is having to be sent off-site for a 'central read.'

Introduction to Medical Imaging Management

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Publisher : CRC Press
ISBN 13 : 1439891842
Total Pages : 200 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Introduction to Medical Imaging Management by : Bernard Rubenzer

Download or read book Introduction to Medical Imaging Management written by Bernard Rubenzer and published by CRC Press. This book was released on 2013-01-14 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past, for the most part, people who moved into management positions in medical imaging were chosen because they were the best technologists. However, the skill set for technologists and supervisors/managers are vastly different. Even an MBA-educated person may not be ready to take on imaging management. As an example, when buying a very expensive piece of imaging equipment, this person would not necessarily know the right questions to ask, such as: What is my guaranteed uptime? Is technologist training included? Introduction to Medical Imaging Management is a comprehensive reference for medical imaging managers learning through a combination of education and experience. This thorough book provides an in-depth overview of every major facet pertaining to the knowledge and skills necessary to become a department or imaging center supervisor or manager. The text follows a natural progression from transitioning into a management position and dealing with former peers through the most sophisticated skills uniquely applicable to medical imaging management. Covering all aspects of the profession—operations, human resources, finance, and marketing—this reference is a must-have for any potential, new, or less experienced imaging manager.

Medical Imaging

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Publisher : John Wiley & Sons
ISBN 13 : 1118480244
Total Pages : 453 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Medical Imaging by : Anthony B. Wolbarst

Download or read book Medical Imaging written by Anthony B. Wolbarst and published by John Wiley & Sons. This book was released on 2013-04-02 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: "An excellent primer on medical imaging for all members of the medical profession . . . including non-radiological specialists. It is technically solid and filled with diagrams and clinical images illustrating important points, but it is also easily readable . . . So many outstanding chapters . . . The book uses little mathematics beyond simple algebra [and] presents complex ideas in very understandable terms." —Melvin E. Clouse, MD, Vice Chairman Emeritus, Department of Radiology, Beth Israel Deaconess Medical Center and Deaconess Professor of Radiology, Harvard Medical School A well-known medical physicist and author, an interventional radiologist, and an emergency room physician with no special training in radiology have collaborated to write, in the language familiar to physicians, an introduction to the technology and clinical applications of medical imaging. It is intentionally brief and not overly detailed, intended to help clinicians with very little free time rapidly gain enough command of the critically important imaging tools of their trade to be able to discuss them confidently with medical and technical colleagues; to explain the general ideas accurately to students, nurses, and technologists; and to describe them effectively to concerned patients and loved ones. Chapter coverage includes: Introduction: Dr. Doe's Headaches Sketches of the Standard Imaging Modalities Image Quality and Dose Creating Subject Contrast in the Primary X-Ray Image Twentieth-Century (Analog) Radiography and Fluoroscopy Radiation Dose and Radiogenic Cancer Risk Twenty-First-Century (Digital) Imaging Digital Planar Imaging Computed Tomography Nuclear Medicine (Including SPECT and PET) Diagnostic Ultrasound (Including Doppler) MRI in One Dimension and with No Relaxation Mapping T1 and T2 Proton Spin Relaxation in 3D Evolving and Experimental Modalities

Diagnostic Imaging: Nuclear Medicine E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323400442
Total Pages : 602 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Diagnostic Imaging: Nuclear Medicine E-Book by : Paige A Bennett

Download or read book Diagnostic Imaging: Nuclear Medicine E-Book written by Paige A Bennett and published by Elsevier Health Sciences. This book was released on 2015-10-13 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: A tactical guide for radiologists and nuclear medicine physicians, Diagnostic Imaging: Nuclear Medicine, Second Edition is practical, easy-to-use, and in-touch with the realities of multimodality diagnostic imaging. This comprehensive yet accessible reference addresses the most appropriate nuclear medicine options available to answer specific clinical questions within the framework of all imaging modalities. Sweeping updates include a complete reorganization, new differential diagnoses based on findings, and new chapters on physics and Nuclear Regulatory Commission guidelines. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need! Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, 2,000 full-color annotated images, and an extensive index Expanded coverage of the most important topics and trends in nuclear medicine including Recently revised radioactive iodine therapy guidelines for hyperthyroidism and thyroid cancer New bone tumor therapy radium-223 (currently indicated for treatment of painful bone metastases in prostate cancer) New I-123 ioflupane dopamine transporter imaging for diagnosis of parkinsonian syndromes F-18 PET/CT bone scan (particularly its indication for nonaccidental trauma in children) Meticulous updates throughout reflect the latest advances as well as all study guide topics listed for the new American Board of Radiology exam, including physics and Nuclear Regulatory Commission guidelines Expert Consult eBook version included with purchase allows you to search all of the text, figures, and references from the book on a variety of devices

How to Implement the Pharmacists' Patient Care Process

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Publisher : American Pharmacists Association (APhA)
ISBN 13 : 9781582122564
Total Pages : 0 pages
Book Rating : 4.1/5 (225 download)

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Book Synopsis How to Implement the Pharmacists' Patient Care Process by : American Pharmacists Association

Download or read book How to Implement the Pharmacists' Patient Care Process written by American Pharmacists Association and published by American Pharmacists Association (APhA). This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication introduces the Pharmacists' Patient Care Process, which was adopted in May 2014 by the Joint Commission of Pharmacy Practitioners (JCPP), a group of 11 national pharmacy organizations. The goal is to help pharmacists understand the components of the standard patient care process and apply the process to patients in all pharmacy practice settings.

Clinician's Guide to Diagnostic Imaging

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Publisher : Springer Science & Business Media
ISBN 13 : 1461487692
Total Pages : 180 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Clinician's Guide to Diagnostic Imaging by : William R. Reinus

Download or read book Clinician's Guide to Diagnostic Imaging written by William R. Reinus and published by Springer Science & Business Media. This book was released on 2013-10-21 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise guide to ordering radiology tests for diagnosis and treatment and provides best practice guidelines for patients whose management depends on a clinical question that is best approached through imaging. Organized primarily by organ system, it outlines considerations in selecting the most efficacious imaging studies based on the clinical history, laboratory values, and physical findings to arrive cost-effectively at a correct diagnosis. It also explores the current limitations of each imaging modality and presents evidence-based information to insure that patient safety considerations are observed when ordering potentially dangerous examinations. Clinician’s Guide to Diagnostic Imaging is a valuable resource for all physicians who regularly order imaging studies, including primary care physicians, family practitioners, internists, and surgeons alike. Further, this volume serves as an invaluable reference for medical students who are exposed to medical imaging for their first time or who are rotating through a radiology elective in medical school.

Medical Imaging for Health Professionals

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Publisher : John Wiley & Sons
ISBN 13 : 1119120284
Total Pages : 552 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Medical Imaging for Health Professionals by : Raymond M. Reilly

Download or read book Medical Imaging for Health Professionals written by Raymond M. Reilly and published by John Wiley & Sons. This book was released on 2019-02-06 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the most common imaging technologies and their diagnostic applications so that pharmacists and other health professionals, as well as imaging researchers, can understand and interpret medical imaging science This book guides pharmacists and other health professionals and researchers to understand and interpret medical imaging. Divided into two sections, it covers both fundamental principles and clinical applications. It describes the most common imaging technologies and their use to diagnose diseases. In addition, the authors introduce the emerging role of molecular imaging including PET in the diagnosis of cancer and to assess the effectiveness of cancer treatments. The book features many illustrations and discusses many patient case examples. Medical Imaging for Health Professionals: Technologies and Clinical Applications offers in-depth chapters explaining the basic principles of: X-Ray, CT, and Mammography Technology; Nuclear Medicine Imaging Technology; Radionuclide Production and Radiopharmaceuticals; Magnetic Resonance Imaging (MRI) Technology; and Ultrasound Imaging Technology. It also provides chapters written by expert radiologists in well-explained terminology discussing clinical applications including: Cardiac Imaging; Lung Imaging; Breast Imaging; Endocrine Gland Imaging; Abdominal Imaging; Genitourinary Tract Imaging; Imaging of the Head, Neck, Spine and Brain; Musculoskeletal Imaging; and Molecular Imaging with Positron Emission Tomography (PET). Teaches pharmacists, health professionals, and researchers the basics of medical imaging technology Introduces all of the customary imaging tools—X-ray, CT, ultrasound, MRI, SPECT, and PET—and describes their diagnostic applications Explains how molecular imaging aids in cancer diagnosis and in assessing the effectiveness of cancer treatments Includes many case examples of imaging applications for diagnosing common diseases Medical Imaging for Health Professionals: Technologies and Clinical Applications is an important resource for pharmacists, nurses, physiotherapists, respiratory therapists, occupational therapists, radiological or nuclear medicine technologists, health physicists, radiotherapists, as well as researchers in the imaging field.

Understanding Medical Terms

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Publisher : Routledge
ISBN 13 : 1000170187
Total Pages : 446 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Understanding Medical Terms by : Robert J. Holt

Download or read book Understanding Medical Terms written by Robert J. Holt and published by Routledge. This book was released on 2020-06-29 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: PREFACE TO THE SECOND EDITION The need for a thorough understanding of medical terminology has not diminished in the least for pharmacists and other health care practitioners in the five years between the publication of the first edition of this book and this second edition. If anything, it has become greater. The pharmacy profession has further solidified its clinical role in patient care, and pharmacists are more entrenched than ever before in the role of counselor and advisor to both patients and practitioners alike. For more than a few pharmacists, what not long ago was an occasional question from a physician about appropriate drug therapy has become regular consultation concerning the interaction of drugs with the patient, his life, and the many other therapies he may be facing. Pharmacy chains, which not long ago installed glass walls to separate the pharmacist from customers, have asked technicians to count pills while pharmacists are in continuous contact with the patient. Such practice changes have increased the demand for clinical knowledge among pharmacists, including a knowledge of medical terminology, and those demands have been passed on to the authors in preparation of the second edition of this book. While the role of the text is still to help pharmacists be more effective interpreters and counselors, some changes have been made in response to reader requests.

Clark’s Procedures in Diagnostic Imaging

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Publisher : CRC Press
ISBN 13 : 1498715524
Total Pages : 2044 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Clark’s Procedures in Diagnostic Imaging by : Stewart A Whitley

Download or read book Clark’s Procedures in Diagnostic Imaging written by Stewart A Whitley and published by CRC Press. This book was released on 2020-01-06 with total page 2044 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together conventional contrast media studies, computed tomography, ultrasound, magnetic resonance imaging, radionuclide imaging including hybrid imaging using SPECT-CT and PET-CT, DXA studies and digital interventional procedures into one volume, this definitive book is the essential source of information on the use and application of these imaging modalities in radiography. Taking a systemic anatomical approach, carefully designed to be clear and consistent throughout and mirroring that in the popular and established textbook Clark’s Positioning in Radiography, each chapter is highly illustrated and contains sections detailing anatomy, pathologic considerations, procedure methodology, and an evaluation of recommended imaging modalities. Reflecting the latest clinical imaging pathways and referral guidelines including IR(ME)R 2017, the Map of Medicine and RCR iRefer (8E), Clark’s Diagnostic Imaging Procedures will quickly become established as the standard textbook for students of radiography and radiographer assistant trainees and an invaluable desk reference for practising radiologists.

Fundamentals of Nuclear Pharmacy

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Publisher : Springer
ISBN 13 : 3319575805
Total Pages : 428 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Fundamentals of Nuclear Pharmacy by : Gopal B. Saha

Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer. This book was released on 2017-11-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Advancing Nuclear Medicine Through Innovation

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Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Diagnostic Imaging

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Publisher :
ISBN 13 : 9780808923824
Total Pages : 0 pages
Book Rating : 4.9/5 (238 download)

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Book Synopsis Diagnostic Imaging by : Kathryn A. Morton

Download or read book Diagnostic Imaging written by Kathryn A. Morton and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents guidance on nuclear imaging. It offers details for each diagnosis, representative images, case data and current references.

Pharmaco-Imaging in Drug and Biologics Development

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Publisher : Springer
ISBN 13 : 9781461482482
Total Pages : 401 pages
Book Rating : 4.4/5 (824 download)

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Book Synopsis Pharmaco-Imaging in Drug and Biologics Development by : Brian R. Moyer

Download or read book Pharmaco-Imaging in Drug and Biologics Development written by Brian R. Moyer and published by Springer. This book was released on 2013-11-09 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this period by adding high value data, the images and the kinetic information they can provide, and cost-effective development alternative tools which potentially improve pivotal study designs. Imaging may identify safety issues early such as unwanted organ or tissue distributions, and then can serve advanced development with added certainty of a drug or biologic’s success to senior corporate management and investors. There are numerous textbooks, reference texts and treatises on medical imaging technologies, teaching tools on medical cases and physics books on the science of detector and computer interface systems. Rarely, in each of these are examples of medical imaging protocols and animal models of disease i.e. a text on methodology in drug development is currently unavailable.