Developmental Biology And Musculoskeletal Tissue Engineering

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Developmental Biology and Musculoskeletal Tissue Engineering

Author : Martin J. Stoddart
Publisher : Academic Press
ISBN 13 : 0128115386
Total Pages : 270 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Developmental Biology and Musculoskeletal Tissue Engineering by : Martin J. Stoddart

Download or read book Developmental Biology and Musculoskeletal Tissue Engineering written by Martin J. Stoddart and published by Academic Press. This book was released on 2018-04-24 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine

Author : Justin Brown
Publisher : Academic Press
ISBN 13 : 0128033991
Total Pages : 252 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine by : Justin Brown

Download or read book Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine written by Justin Brown and published by Academic Press. This book was released on 2016-11-03 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine Focuses on how materials of structures can be designed to be resistant while promoting viable grafts Contains major tissue types that are covered with a strategy for each material and structure

Musculoskeletal Tissue Regeneration

Author : William S. Pietrzak
Publisher : Springer Science & Business Media
ISBN 13 : 1597452394
Total Pages : 649 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Musculoskeletal Tissue Regeneration by : William S. Pietrzak

Download or read book Musculoskeletal Tissue Regeneration written by William S. Pietrzak and published by Springer Science & Business Media. This book was released on 2008-04-11 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

Tendon Regeneration

Author : Manuela E. Gomes
Publisher : Academic Press
ISBN 13 : 9780443159169
Total Pages : 0 pages
Book Rating : 4.1/5 (591 download)

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Book Synopsis Tendon Regeneration by : Manuela E. Gomes

Download or read book Tendon Regeneration written by Manuela E. Gomes and published by Academic Press. This book was released on 2024-08-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes was the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies.Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective field's present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field.New coverage will include signaling pathways for tendon development, molecular mechanisms of tendinopathy, inflammation contribution to healing and pathology of tendons, tendon aging and degeneration, tendon models, and translational studies for tendon regenerative medicine.

Nanocomposites for Musculoskeletal Tissue Regeneration

Author : Huinan Liu
Publisher : Woodhead Publishing
ISBN 13 : 178242475X
Total Pages : 406 pages
Book Rating : 4.7/5 (824 download)

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Book Synopsis Nanocomposites for Musculoskeletal Tissue Regeneration by : Huinan Liu

Download or read book Nanocomposites for Musculoskeletal Tissue Regeneration written by Huinan Liu and published by Woodhead Publishing. This book was released on 2016-02-23 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass

Principles of Tissue Engineering

Author : Robert Lanza
Publisher : Academic Press
ISBN 13 : 0123983703
Total Pages : 1936 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Principles of Tissue Engineering by : Robert Lanza

Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Academic Press. This book was released on 2013-10-17 with total page 1936 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout

Nanoengineering in Musculoskeletal Regeneration

Author : Mehdi Razavi
Publisher : Academic Press
ISBN 13 : 0128202637
Total Pages : 290 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Nanoengineering in Musculoskeletal Regeneration by : Mehdi Razavi

Download or read book Nanoengineering in Musculoskeletal Regeneration written by Mehdi Razavi and published by Academic Press. This book was released on 2020-05-09 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline—from biomedical discovery to clinical implementation—aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation. Provides broad coverage in all research areas focused on the applications of nanotechnology in musculoskeletal regeneration Offers useful guidance for physician-scientists with expertise in orthopedics, regenerative medicine, bioengineering, biomaterials, nanoengineering, stem cell biology, and chemistry Serves as a practical reference for many disciplines, including bioengineering, biomaterials, tissue engineering, regenerative medicine, musculoskeletal regenerative medicine, and nanomedicine

Regenerative Engineering of Musculoskeletal Tissues and Interfaces

Author : Syam Nukavarapu
Publisher : Woodhead Publishing
ISBN 13 : 9781782423010
Total Pages : 0 pages
Book Rating : 4.4/5 (23 download)

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Book Synopsis Regenerative Engineering of Musculoskeletal Tissues and Interfaces by : Syam Nukavarapu

Download or read book Regenerative Engineering of Musculoskeletal Tissues and Interfaces written by Syam Nukavarapu and published by Woodhead Publishing. This book was released on 2015-04-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces.

Roles of Skeletal Muscle in Organ Development

Author : Boris Kablar
Publisher : Springer Nature
ISBN 13 : 3031382153
Total Pages : 166 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Roles of Skeletal Muscle in Organ Development by : Boris Kablar

Download or read book Roles of Skeletal Muscle in Organ Development written by Boris Kablar and published by Springer Nature. This book was released on 2023-11-13 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscle is the only tissue of the four basic types that make the body that can be completely ablated while allowing fetal survival. This book is a result of 25 years of research employing engineered mouse fetuses with no skeletal muscle, a model system that provides a unique opportunity to study body development holistically. A systematic anatomical analysis of such fetuses have shown that several anatomical locations are affected by the absence of the skeletal muscle. This book contains a summarized description of affected anatomical locations such as the alveolar lung epithelium, motor neurons and giant pyramidal cells in the CNS, cholinergic amacrine cells of the retina, and type I hair cells of the crista ampullaris. Several specific bioinformatics and systems biology interventions are also described. The book provides an update on skeletal muscle development, musculoskeletal developmental interactions, trophic relationships between the skeletal muscle and the motor neurons, mechanics of lung development, functional development of two special senses, eye and ear, and finally, skeletal muscle-related reasons for human fetal akinesia and its consequences. This volume in the Advances in Anatomy, Embryology and Cell Biology series stresses the need to think about the developing body and its organs in terms of their mutual interdependence, and to think about diseases, such as pulmonary hypoplasia, amyotrophic lateral sclerosis, or cleft palate, in terms of that interdependence. Directed to developmental biologists, neuroscientists, tissue engineers and health professionals, this book exposes the ideas of interorgan communication and interdependence in homeostasis and disease.

Stem Cell Biology and Tissue Engineering in Dental Sciences

Author : Ajaykumar Vishwakarma
Publisher : Academic Press
ISBN 13 : 0123977789
Total Pages : 933 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Stem Cell Biology and Tissue Engineering in Dental Sciences by : Ajaykumar Vishwakarma

Download or read book Stem Cell Biology and Tissue Engineering in Dental Sciences written by Ajaykumar Vishwakarma and published by Academic Press. This book was released on 2014-11-05 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color

Functional Tissue Engineering

Author : Farshid Guilak
Publisher : Springer Science & Business Media
ISBN 13 : 0387955534
Total Pages : 434 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Functional Tissue Engineering by : Farshid Guilak

Download or read book Functional Tissue Engineering written by Farshid Guilak and published by Springer Science & Business Media. This book was released on 2003-07-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: -Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology

Biologic Foundations for Skeletal Tissue Engineering

Author : Ericka M. Bueno
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1608451720
Total Pages : 221 pages
Book Rating : 4.6/5 (84 download)

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Book Synopsis Biologic Foundations for Skeletal Tissue Engineering by : Ericka M. Bueno

Download or read book Biologic Foundations for Skeletal Tissue Engineering written by Ericka M. Bueno and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering research for bone and joint applications entails multidisciplinary teams bringing together the needed expertise in anatomy, biology, biochemistry, pathophysiology, materials science, biomechanics, fluidics, and clinical and veterinary orthopedics. It is the goal of this volume to provide students and investigators who are entering this exciting area with an understanding of the biologic foundations necessary to appreciate the problems in bone and cartilage that may benefit from innovative tissue engineering approaches. This volume includes state-of-the-art information about bone and cartilage physiology at the levels of cell and molecular biology, tissue structure, developmental processes, their metabolic and structural functions, responses to injury, mechanisms of post-natal healing and graft incorporation, the many congenital and acquired disorders, effects of aging, and current clinical standards of care. It reviews the strengths and limitations of various experimental animal models, sources of cells, composition and design of scaffolds, activities of growth factors and genes to enhance histogenesis, and the need for new materials in the context of cell-based and cell-free tissue engineering. These building blocks constitute the dynamic environments in which innovative approaches are needed for addressing debilitating disorders of the skeleton. It is likely that a single tactic will not be sufficient for different applications because of variations in the systemic and local environments. The realizations that tissue regeneration is complex and dynamic underscore the continuing need for innovative multidisciplinary investigations, with an eye to simple and safe therapies for disabled patients. Table of Contents: Introduction / Structure and Function of Bone and Cartilage Tissue / Development / Responses to Injury and Grafting / Clinical Applications for Skeletal Tissue Engineering / Animal Models / Tissue Engineering Principles for Bone and Cartilage / Perspectives

Tissue Engineering in Musculoskeletal Clinical Practice

Author : Linda Jo Sandell
Publisher : American Academy of Orthopedic Surgeons
ISBN 13 :
Total Pages : 450 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Tissue Engineering in Musculoskeletal Clinical Practice by : Linda Jo Sandell

Download or read book Tissue Engineering in Musculoskeletal Clinical Practice written by Linda Jo Sandell and published by American Academy of Orthopedic Surgeons. This book was released on 2004 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: When will tissue-engineered materials be ready for the OR? How will they be introduced into clinics? What's available in the field now? Tissue Engineering answers these questions and brings insight into the potential for tissue engineering as a biological solution to the critical need for human tissues in orthopaedic surgery. This book is a compilation of the proceedings of the Tissue Engineering in Musculoskeletal Clinical Practice workshop held in Santa Fe, NM in January 2003. It is written by orthopaedic surgeons for practical application. Tissue Engineering addresses the present and future direction of the clinical, scientific and business aspects of the development and application of tissue engineered materials in orthopaedic surgery. Sections address clinical and marketing challenges, methodologies used in the construction of tissue engineered materials, as well as tissue engineering of bone, cartilage, ligament, tendon, meniscus, invertebral disk and muscle

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine

Author : Johnny Huard
Publisher : Springer Science & Business Media
ISBN 13 : 1461221269
Total Pages : 294 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine by : Johnny Huard

Download or read book Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine written by Johnny Huard and published by Springer Science & Business Media. This book was released on 2013-03-11 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written in response to the many physicians and scien tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Tissue Engineering and Developmental Biology

Author : Shay Fisher
Publisher :
ISBN 13 : 9781682861677
Total Pages : 0 pages
Book Rating : 4.8/5 (616 download)

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Book Synopsis Tissue Engineering and Developmental Biology by : Shay Fisher

Download or read book Tissue Engineering and Developmental Biology written by Shay Fisher and published by . This book was released on 2016-05-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering has revolutionized the field of medical science. The scientific progress in the development of biomaterials and stem cells has further accelerated the growth of this discipline. This book is dedicated to the emerging trends in different aspects of tissue engineering and developmental biology such as synthesis, spectroscopy, etc. It also focuses on the tools and techniques for regeneration of germlings and seedlings along with autografts. This book aims to serve as a valuable source of reference for students, academicians and researchers.

Regenerative Engineering and Developmental Biology

Author : David M. Gardiner
Publisher : CRC Press
ISBN 13 : 9781498723312
Total Pages : 624 pages
Book Rating : 4.7/5 (233 download)

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Book Synopsis Regenerative Engineering and Developmental Biology by : David M. Gardiner

Download or read book Regenerative Engineering and Developmental Biology written by David M. Gardiner and published by CRC Press. This book was released on 2017-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: SECTION IV: PRINCIPLES OF ORGAN DEVELOPMENT AND REGENERATION -- 20: Functional ectodermal organ regeneration based on epithelial and mesenchymal interactions -- 21: Blastema formation in mammalian digit-tip regeneration -- 22: Spinal cord repair and regeneration -- 23: Heart regeneration -- 24: Eye tissue regeneration and engineering -- 25: Skin development and regeneration, and the control of fibrosis -- 26: Programming cells to build tissues with synthetic biology: A new pathway toward engineering development and regeneration -- 27: Recurrent concepts -- Index

Bone Tissue Engineering

Author : Jeffrey O. Hollinger
Publisher : CRC Press
ISBN 13 : 1135501912
Total Pages : 500 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger

Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t