Tendon Regeneration

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Tendon Regeneration

Author : Manuela E Gomes
Publisher : Academic Press
ISBN 13 : 0128016000
Total Pages : 470 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Tendon Regeneration by : Manuela E Gomes

Download or read book Tendon Regeneration written by Manuela E Gomes and published by Academic Press. This book was released on 2015-08-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. Provides an overview of tendon biology, disease, and tissue engineering approaches Presents modern, alternative approaches to developing functional tissue solutions discussed Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field

Repair and Regeneration of Ligaments, Tendons, and Joint Capsule

Author : William R. Walsh
Publisher : Springer Science & Business Media
ISBN 13 : 1592599427
Total Pages : 324 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Repair and Regeneration of Ligaments, Tendons, and Joint Capsule by : William R. Walsh

Download or read book Repair and Regeneration of Ligaments, Tendons, and Joint Capsule written by William R. Walsh and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and authoritative review of the most important scientific and clinically relevant topics today in ligaments, tendons, and capsular biology, including their biomechanics and surgical reconstruction. The authors review the basic science of tendons in the hand and shoulder ligaments, the current clinical status of the shoulder and cruciate ligaments, and the latest advances in research on the healing of ligament and tendon to bone, artificial ligaments, and gene therapy. They also cover the major type 1 collagen soft tissues that are of particular interest to upper extremity surgeons and sports medicine specialists.

Biomechanics of Tendons and Ligaments

Author : Johanna Buschmann
Publisher : Woodhead Publishing
ISBN 13 : 0081004923
Total Pages : 350 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Biomechanics of Tendons and Ligaments by : Johanna Buschmann

Download or read book Biomechanics of Tendons and Ligaments written by Johanna Buschmann and published by Woodhead Publishing. This book was released on 2017-05-10 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks at the structure and function of tendons and ligaments. Biological and synthetic biomaterials for their reconstruction and regeneration are reviewed, and their biomechanical performance is discussed. Regeneration tendons and ligaments are soft connective tissues which are essential for the biomechanical function of the skeletal system. These tissues are often prone to injuries which can range from repetition and overuse, to tears and ruptures. Understanding the biomechanical properties of ligaments and tendons is essential for their repair and regeneration. Contains systematic coverage on how both healthy and injured tendons and ligaments work Includes coverage of repair and regeneration strategies for tendons and ligaments Presents an Interdisciplinary analysis on the topic

Inflammation and tendon healing

Author : Parmis Blomgran
Publisher : Linköping University Electronic Press
ISBN 13 : 917685471X
Total Pages : 45 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Inflammation and tendon healing by : Parmis Blomgran

Download or read book Inflammation and tendon healing written by Parmis Blomgran and published by Linköping University Electronic Press. This book was released on 2017-10-30 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendons heal through three different overlapping phases; the inflammatory, proliferative and remodeling phase. Many studies have investigated what factors influence healing of tendons. However, little was known about inflammation and the immune cells present during Achilles tendon healing by the time this thesis started. We developed a flow cytometry method for our rat model of tendon healing, which enabled us to study different leukocyte subpopulations during Achilles tendon healing. The general aim of this thesis was to understand more about inflammation and the immune cell populations present during tendon healing and how the immune cell composition changes during normal tendon healing. Moreover, we investigated how different factors that are known to influence tendon healing affected the composition of the immune cell population. First, we described the immune cells during the time course of tendon healing focusing on different subpopulations of macrophages and T cells. Then, we studied how these cells were influenced by reduced mechanical loading. Mechanical loading prolonged the presence of M1 macrophages and delayed the switch to regulatory T cells and M2 macrophages compared to reduced mechanical loading. Next, the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on the leukocyte composition revealed that, even though NSAIDs influence the mechanical properties of healing tendon, this effect was not mediated via changes in the leukocyte sub-populations during early and mid-time tendon healing. Further, the effect of corticosteroids during the inflammatory and remodeling phases of tendon healing was an improved healing of tendons and a reduction of CD8a T cells when corticosteroid was administered after the inflammatory phase. Lastly, we investigated if impairment of tendon healing by NSAIDs was related to mechanotransduction or microdamage during mechanical loading and showed that NSAIDs impair tendon healing by reducing the response to microdamage. In conclusion, these studies show that inflammation plays an important role during Achilles tendon healing, and factors that influence healing can also alter the presence or polarization of immune cell populations.

Cell Engineering and Regeneration

Author : Heinz Redl
Publisher : Springer
ISBN 13 : 9783319088303
Total Pages : 0 pages
Book Rating : 4.0/5 (883 download)

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Book Synopsis Cell Engineering and Regeneration by : Heinz Redl

Download or read book Cell Engineering and Regeneration written by Heinz Redl and published by Springer. This book was released on 2017-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

Tendons

Author : Hasan Sözen
Publisher : BoD – Books on Demand
ISBN 13 : 1839629851
Total Pages : 166 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Tendons by : Hasan Sözen

Download or read book Tendons written by Hasan Sözen and published by BoD – Books on Demand. This book was released on 2019-12-04 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mankind has reached its present physical form through evolution of the movement system. Muscles, bones, and joints are the most important components of the movement system. Muscles are active elements, while bones and joints are passive elements. But to bring about movement, these three elements must work together. Tendons are round, oval, or flat tissues that connect muscles to bones. Muscle, tendon, or ligament injuries prevent motion so this is an important issue in trauma. If muscle, tendon, or ligament injuries occur together with vessel or nerve injury, it may be life threatening. The cause of injury might differ from a simple sports injury to a serious traffic accident. Muscles, bones, and joints have taken their place in the literature, but it would be wrong to say the same for tendons. This book describes tendons from different perspectives, thus providing the missing information in the literature. I hope that this book will be useful for anyone who wants to read about new perspectives on tendons. I also hope that it will inspire researchers working in this field.

Tendon and Ligament Healing

Author : William Weintraub
Publisher : Redwing Book Company
ISBN 13 : 0912111739
Total Pages : 249 pages
Book Rating : 4.9/5 (121 download)

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Book Synopsis Tendon and Ligament Healing by : William Weintraub

Download or read book Tendon and Ligament Healing written by William Weintraub and published by Redwing Book Company. This book was released on 2003 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 25 years of practicing structural/osteopathic manual therapy the author has done considerable work with seriously damaged tendons and ligaments, and has achieved results that conventional medicine would rate as improbable. Over time, he has developed a therapeutic model for treating these injuries so that individuals with chronic conditions -- who have exhausted the standard physiotherapy options and are facing surgery -- can have a viable option for recovery. His techniques, based on basic principles of structural healthcare, emphasize the importance of precise anatomical focus and the capacity to work with subtle changes of structure. Of essential importance is combining detailed specific treatment of the small fibers and tissues of the local injury area with an overall approach to improving larger body patterns and tensions. Logically, the responsiveness and self-corrective capacity of body tissues when given proper conditions is also an important factor. The primary techniques used are the osteopathic methods of strain-counterstrain, cranial and visceral osteopathy, and fascial release, as well as body-mind centering, zero balancing, and acupressure. His clinical model, which represents a new approach to serious, chronic tendon and ligament injuries, is based on these techniques, their combinations and specific usage, and the skills and aptitudes necessary for applying these techniques, including certain perceptual skills and a thorough knowledge of anatomy and kinesiology. Weintraub's descriptions are vital, interesting, alive, absorbing, even dramatic. He discusses at great length the nature of the tendons and ligaments, describes his manual therapy model -- comparing it with conventional medical procedures -- and covers processes and tissue changes in tendon/ligament healing as related to manual therapy. Case studies, self-help strategies, and thoughtful words on clinical efficacy and future directions in the field make for a thorough and well-rounded presentation. (Product Description).

Regenerative Medicine and Plastic Surgery

Author : Dominik Duscher
Publisher : Springer Nature
ISBN 13 : 3030199622
Total Pages : 480 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Regenerative Medicine and Plastic Surgery by : Dominik Duscher

Download or read book Regenerative Medicine and Plastic Surgery written by Dominik Duscher and published by Springer Nature. This book was released on 2019-11-27 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addresses muscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Muscle and Tendon Injuries

Author : Gian Luigi Canata
Publisher : Springer
ISBN 13 : 366254184X
Total Pages : 450 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis Muscle and Tendon Injuries by : Gian Luigi Canata

Download or read book Muscle and Tendon Injuries written by Gian Luigi Canata and published by Springer. This book was released on 2017-05-10 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in a comprehensive manner the causes and symptoms of muscle and tendon pathologies, the available diagnostic procedures, and current treatment approaches. Specific aspects of the anatomy, biomechanics, and function of muscles and tendons are analyzed, and detailed guidance is provided on the most innovative methods – both conservative and surgical – for ensuring that the athlete can make a safe and quick return to sporting activity. Optimal care of tendon and muscle injuries in sportspeople requires effective cooperation of sports scientists and medical practitioners to identify the best ways of preserving muscle and tendon structures and to develop new strategies for their rehabilitation and regeneration. Muscle and Tendon Injuries is an excellent multidisciplinary reference written by the leading experts in the field and published in collaboration with ISAKOS. It will appeal to all specialists in sports medicine and sports traumatology who are seeking a state of the art update on the management of muscle and tendon disorders.

Tendon Healing

Author : Malin Hammerman
Publisher : Linköping University Electronic Press
ISBN 13 : 9176853616
Total Pages : 28 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Tendon Healing by : Malin Hammerman

Download or read book Tendon Healing written by Malin Hammerman and published by Linköping University Electronic Press. This book was released on 2018-02-20 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanical loading and the inflammatory response during tendon healing might be important for the healing process. Mechanical loading can improve the healing tendon but the mechanism is not fully understood. The aim of this thesis was to further clarify the effect of mechanical loading on tendon healing and how mechanical loading affects the inflammatory response during the healing process. We used a rat Achilles tendon model to study healing. The rats were exposed to different degrees of loading by unloading methods such as paralysis of the calf muscles with Botox, tail suspension, and an orthosis (a boot). Full loading was achieved by free cage activity or treadmill walking. Microdamage in tendons, unloaded with Botox, was also investigated by needling. The healing tendons were evaluated in a materials testing machine (to analyze the mechanical properties), by gene expression analysis (microarray and PCR), or histology. Our results show that moderate loading (unloading with Botox) improves the mechanical properties of healing tendons compared to minimal loading (unloading with Botox in combination with tail suspension or a boot), especially the material properties. In accordance to these findings, expression of extracellular matrix genes were also increased by moderate compared to minimal loading. Full loading improved all mechanical properties and the expression of extracellular matrix genes was further increased compared to moderate loading. However, structural properties, such as the strength and the size of the healing tendon, were more affected by full loading. Full loading also affected the expression of inflammation-related genes during the early healing phase, 3 and 5 days after tendon injury, and increased the number of immune cells in the healing tendon tissue. Also microdamage of the healing tendon (detected by blood leakage) was increased by full loading compared to moderate loading during the early healing phase. Induced microdamage by repeated needling in the healing tendon tissue increased the structural properties of the healing tendon. The gene expression after needling was similar to the gene expression after full loading. The improvement of mechanical properties by loading in healing tendons was decreased by an anti-inflammatory drug called parecoxib, which decreases the production of prostaglandins by inhibiting COX-2 activity. The effect of parecoxib was reduced when loading was reduced but we could not confirm that the effect of parecoxib was related to the degree of loading. However, parecoxib abolished the stimulatory effect of microdamage. In conclusion, these studies show that moderate loading improves the quality of the healing tendon whereas full loading also increases the quantity of the healing tendon tissue. Full loading creates microdamage and increases inflammation during the early healing phase. The strong effect of full loading on the structural properties might be due to microdamage. Indeed, the anti-inflammatory drug parecoxib seems to impair mechanical stimulation of healing tendons by reducing the response to microdamage.

Biointegration of Medical Implant Materials

Author : Chandra P. Sharma
Publisher : Elsevier
ISBN 13 : 1845699807
Total Pages : 424 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Biointegration of Medical Implant Materials by : Chandra P. Sharma

Download or read book Biointegration of Medical Implant Materials written by Chandra P. Sharma and published by Elsevier. This book was released on 2010-07-13 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue. Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering. With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery

A Tissue Regeneration Approach to Bone and Cartilage Repair

Author : Hala Zreiqat
Publisher : Springer
ISBN 13 : 3319132660
Total Pages : 254 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis A Tissue Regeneration Approach to Bone and Cartilage Repair by : Hala Zreiqat

Download or read book A Tissue Regeneration Approach to Bone and Cartilage Repair written by Hala Zreiqat and published by Springer. This book was released on 2014-12-05 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

Orthocell's Ortho-ATI

Author : Ming Hao Zheng
Publisher : Jerome Waddell
ISBN 13 :
Total Pages : 43 pages
Book Rating : 4./5 ( download)

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Book Synopsis Orthocell's Ortho-ATI by : Ming Hao Zheng

Download or read book Orthocell's Ortho-ATI written by Ming Hao Zheng and published by Jerome Waddell. This book was released on 2015-05-14 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orthocell's Ortho-ATI. Tendon regeneration biotechnology. Tendon Injury Intervention.

Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms

Author : Luciano Merlini
Publisher : Frontiers Media SA
ISBN 13 : 2889451038
Total Pages : 106 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms by : Luciano Merlini

Download or read book Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms written by Luciano Merlini and published by Frontiers Media SA. This book was released on 2017-02-24 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is characterized by progressive deterioration of walking ability. This function loss has multiple causes including central and peripheral nerve dysfunction, loss of muscle mass and strength, as well as joints and bone alterations. Muscle-tendon unit and its innervation has a pivotal role in motor function performance that can be disrupted by overuse degeneration and aging. Research has shown that overuse degeneration and aging also share some pathophysiological mechanisms including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and modification of signalling and stress response pathways. This Research Topic is intended to bring together basic researchers and clinicians working in the area of neuroscience, aging, sarcopenia and orthopaedics in human and in animal models. The aim of this cross-fertilization is to accelerate our understanding of the mechanisms involved in aging and degeneration of the muscle-tendon unit and its innervation and to explore the therapeutic potential of pharmacological and physical therapy interventions.

Tendon Injury and Repair

Author : Terry S. Saxby
Publisher :
ISBN 13 : 9781416050711
Total Pages : 0 pages
Book Rating : 4.0/5 (57 download)

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Book Synopsis Tendon Injury and Repair by : Terry S. Saxby

Download or read book Tendon Injury and Repair written by Terry S. Saxby and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tendon problems are a common cause of foot and ankle pathology. In the past decade there has been significant advances in the management of these problems. This has been achieved not only by an improvement of surgical techniques but also through a better understanding of tendon injury and healing. In this issue we will review the recent advances in the diagnosis and treatment of common tendon problems beginning with a review of tendon healing. This issue will provide the reader with an excellent review of all that is new on this topic.

Tendinopathy in Athletes

Author : Savio L-Y. Woo
Publisher : John Wiley & Sons
ISBN 13 : 0470757973
Total Pages : 248 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Tendinopathy in Athletes by : Savio L-Y. Woo

Download or read book Tendinopathy in Athletes written by Savio L-Y. Woo and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise volume in the Encyclopaedia of Sports Medicine series, published under the auspices of the International Olympic Committee, provides a dependable source of current knowledge available on tendinopathy and covers both the basic science and clinical aspects of the subject. Despite its high incidence, the precise etiopathogenesis and effective treatment of tendinopathy remain elusive. Tendinopathy in Athletes draws on the expertise of an international and prolific collection of contributors, both clinicians and scientists, who provide new insights into this specialized area. This book: provides a comprehensive resource for both clinicians and researchers with information organized logically, with an easy-to-follow progression from the basic scientific findings to clinical applications discusses the full range of treatment modalities, including new molecular and biological approaches, plus surgical and alternative approaches to tendinopath contains “What We Need to Know” sections that suggest future areas of research for young investigators. As tendinopathy remains one of the most common injuries encountered, both in sports and at the workplace, this essential volume is sure to be a source of frequent consultation.

Electrospinning for Tissue Regeneration

Author : L Bosworth
Publisher : Elsevier
ISBN 13 : 085709291X
Total Pages : 424 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Electrospinning for Tissue Regeneration by : L Bosworth

Download or read book Electrospinning for Tissue Regeneration written by L Bosworth and published by Elsevier. This book was released on 2011-06-21 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrospinning is a simple and highly versatile method for generating ultrathin fibres with diameters ranging from a few micrometres to tens of nanometres. Although most commonly associated with textile manufacturing, recent research has proved that the electrospinning technology can be used to create organ components and repair damaged tissues. Electrospinning for tissue regeneration provides a comprehensive overview of this innovative approach to tissue repair and regeneration and examines how it is being employed within the biomaterials sector. The book opens with an introduction to the fundamentals of electrospinning. Chapters go on to discuss polymer chemistry, the electrospinning process, conditions, control and regulatory issues. Part two focuses specifically on electrospinning for tissue regeneration and investigates its uses in bone, cartilage, muscle, tendon, nerve, heart valve, bladder, tracheal, dental and skin tissue regeneration before concluding with a chapter on wound dressings. Part three explores electrospinning for in vitro applications. Chapters discuss cell culture systems for kidney, pancreatic and stem cell research. With its distinguished editors and international team of expert contributors, Electrospinning for tissue regeneration is a valuable reference tool for those in academia and industry concerned with research and development in the field of tissue repair and regeneration. Provides a comprehensive overview of this innovative approach to tissue repair and regeneration covering issues from polymer chemistry to the regulatory process Examines employment within the biomaterials sector, reviewing extensive applications in areas such as uses in bone, muscle tendon, heart valve and tissue regeneration Explores electrospinning for in vitro applications and discusses cell culture systems for kidney, pancreatic and stem cell research