Developmental And Fetal Origins Of Differences In Monozygotic Twins

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Developmental and Fetal Origins of Differences in Monozygotic Twins

Author : Alexandra Matias
Publisher : Academic Press
ISBN 13 : 0128203072
Total Pages : 386 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Developmental and Fetal Origins of Differences in Monozygotic Twins by : Alexandra Matias

Download or read book Developmental and Fetal Origins of Differences in Monozygotic Twins written by Alexandra Matias and published by Academic Press. This book was released on 2020-05-15 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis Features contributions from international experts in twin genetics and developmental biology

3D Physical and Virtual Models in Fetal Medicine

Author : Heron Werner
Publisher : Springer Nature
ISBN 13 : 303114855X
Total Pages : 197 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis 3D Physical and Virtual Models in Fetal Medicine by : Heron Werner

Download or read book 3D Physical and Virtual Models in Fetal Medicine written by Heron Werner and published by Springer Nature. This book was released on 2023-05-26 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological innovations accompanying advances in medicine have given rise to the possibility of obtaining better-defined fetal images that assist in medical diagnosis and contribute toward genetic counseling offered to parents during the prenatal care. 3D printing is an emerging technique with a variety of medical applications such as surgical planning, biomedical research and medical education. Clinical Relevance: 3D physical and virtual models from ultrasound and magnetic resonance imaging have been used for educational, multidisciplinary discussion and plan therapeutic approaches. The authors describe techniques that can be applied at different stages of pregnancy and constitute an innovative contribution to research on fetal abnormalities. We will show that physical models in fetal medicine can help in the tactile and interactive study of complex abnormalities in multiple disciplines. They may also be useful for prospective parents because a 3D physical model with the characteristics of the fetus should allow a more direct emotional connection to their unborn child.

Exploring the Biological Contributions to Human Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309132978
Total Pages : 288 pages
Book Rating : 4.1/5 (329 download)

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Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Twin Research for Everyone

Author : Adam D. Tarnoki
Publisher : Academic Press
ISBN 13 : 0128215151
Total Pages : 740 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Twin Research for Everyone by : Adam D. Tarnoki

Download or read book Twin Research for Everyone written by Adam D. Tarnoki and published by Academic Press. This book was released on 2022-08-17 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years. While targeted to undergraduate and graduate students, this compendium will prove a valuable resource for scholars already familiar with twin studies, as well as those coming to the field for the first time. Here, more than forty experts across an array of disciplines examine twinning and twin research methodologies from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods, family and parenting aspects of twinning, twin studies as applied across various disease areas and medical specialties, genetic and epigenetic determinants of differentiation, and academic, neurological and cognitive development. The presentation of existing studies and methods instruction empowers students and researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions. Offers unique insights into twinning rates, mechanisms and factors surrounding twinship Provides clear instruction on both basic and advanced twin research methods and study design Features leading international experts in twin biology, genetics, health and psychology Examines findings from recent twin studies across a broad array of health and behavioral studies

Perinatology

Author : Renato Augusto Moreira de Sá
Publisher : Springer Nature
ISBN 13 : 3030834344
Total Pages : 1295 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Perinatology by : Renato Augusto Moreira de Sá

Download or read book Perinatology written by Renato Augusto Moreira de Sá and published by Springer Nature. This book was released on 2021-11-18 with total page 1295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest evidence-based guidelines for perinatal management and is designed to help obstetricians and neonatologists minimize complications and offer patients the best possible care. Since 1960, there has been a significant increase in basic and clinical investigations on normal and pathological pregnancy in the developed world. This has provided insights into the physiopathology of pregnant women, fetuses and newborns and led to the development of new technologies, bringing about a new medical subspecialty: perinatal medicine. The book is divided into eight main sections: The first examines basic periconceptional care and discusses the ethical aspects of perinatology. The next section focuses on prenatal considerations, such as the nutritional aspects of gestation and puerperium, physical exercise during pregnancy, routine laboratory tests, prenatal care of multiple gestations and the role of the neonatologist in prenatal care. The third and fourth sections then explore fetal evaluation, and clinical intercurrences in pregnancy, respectively. The next section addresses pregnancy complications: prevention, diagnosis and management. The sixth section covers the basic aspects of congenital infections and the seventh examines labor and delivery aspects. Lastly, the final section includes chapters on neonatal assistance. Written by leading experts in obstetrics, neonatology, and perinatology, this thoroughly updated, comprehensive resource reflects the latest information in all areas, including genetics and imaging.

Transforming the Workforce for Children Birth Through Age 8

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309324882
Total Pages : 706 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Transforming the Workforce for Children Birth Through Age 8 by : National Research Council

Download or read book Transforming the Workforce for Children Birth Through Age 8 written by National Research Council and published by National Academies Press. This book was released on 2015-07-23 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.

The Dependent Gene

Author : David S. Moore
Publisher : Macmillan
ISBN 13 : 9780805072808
Total Pages : 324 pages
Book Rating : 4.0/5 (728 download)

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Book Synopsis The Dependent Gene by : David S. Moore

Download or read book The Dependent Gene written by David S. Moore and published by Macmillan. This book was released on 2003-02-05 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an analysis of the nature vs. nuture debate, arguing for an end to the 'either/or' nature of the discussions in favor of a recognition that environmental and genetic factors interact throughout life to form human traits.

Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia

Author : Henry Houlden
Publisher : Frontiers Media SA
ISBN 13 : 2889669041
Total Pages : 141 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia by : Henry Houlden

Download or read book Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia written by Henry Houlden and published by Frontiers Media SA. This book was released on 2021-06-28 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Early Nutrition Programming and Health Outcomes in Later Life: Obesity and beyond

Author : Berthold Koletzko
Publisher : Springer Science & Business Media
ISBN 13 : 1402091737
Total Pages : 192 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Early Nutrition Programming and Health Outcomes in Later Life: Obesity and beyond by : Berthold Koletzko

Download or read book Early Nutrition Programming and Health Outcomes in Later Life: Obesity and beyond written by Berthold Koletzko and published by Springer Science & Business Media. This book was released on 2009-01-31 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity has reached epidemic proportions globally and presents a major challenge to policy makers and clinicians alike. Recent research has suggested that obesity has its origins in early life and that early diet can programme a developing fetus’ and young infant’s future susceptibility to obesity. This volume contains recent findings presented at the International Conference on Early Nutrition Programming and Health Outcomes in Later Life: Obesity and Beyond - a satellite meeting of the 15th European Congress on Obesity, held in Budapest in April 2007. Basic scientific research, data from epidemiological studies and clinical trial results were all presented during the programme. This volume includes articles discussing the evidence for an effect of early nutrition programming on later obesity and cardiovascular risk; the growing evidence for an intergenerational cycle of obesity; the role of maternal leptin in programming appetite; possible cellular mechanisms for altered energy balance, including mitochondrial programming and the effects of regulators of metabolism; and how epigenetic changes might be the fundamental underlying mechanism explaining programming effects. Consumer understanding of the concept of early nutrition programming and the extent to which early nutrition programming is taken into account in infant feeding policies are also discussed.

Vibrant and Healthy Kids

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309493382
Total Pages : 621 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Vibrant and Healthy Kids by : National Academies of Sciences, Engineering, and Medicine

Download or read book Vibrant and Healthy Kids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-12-27 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity.

Chance, Development, and Aging

Author : Caleb Ellicott Finch
Publisher : Oxford University Press, USA
ISBN 13 : 9780195133615
Total Pages : 298 pages
Book Rating : 4.1/5 (336 download)

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Book Synopsis Chance, Development, and Aging by : Caleb Ellicott Finch

Download or read book Chance, Development, and Aging written by Caleb Ellicott Finch and published by Oxford University Press, USA. This book was released on 2000 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chance, Development, and Aging analyzes a subject that has been largelyignored until now: the sources of individual variations in development and agingthat cannot be attributed to genes or the external environment. And by doing so,this book develops new insight on aging and the individual. Gathering andscrutinizing evidence from diverse sources, the authors examine thosedifferences in individuals that arise during development and those that mightinfluence outcomes of aging. Through their research, they pose a new set ofquestions about the contribution of chance events during development, andalthough chance variations during development are well known within thesub-fields of developmental biology, there has been little recognition of theiraffects on variations in adult form and function. Here, the authors confrontthis issue with a fascinating hypothesis: chance variations in form andfunction, arising through development, affect individual base-line functions andindividual responses to the external environment and so modify outcomes ofaging. This book will undoubtedly benefit gerontologists, geneticists,reproductive biologists, and physiologists, and it will fascinate all thoseinterested in the outcomes of aging.

Old and New Perspectives on Mortality Forecasting

Author : Tommy Bengtsson
Publisher : Springer
ISBN 13 : 3030050750
Total Pages : 349 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Old and New Perspectives on Mortality Forecasting by : Tommy Bengtsson

Download or read book Old and New Perspectives on Mortality Forecasting written by Tommy Bengtsson and published by Springer. This book was released on 2019-03-28 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecasting, the linearity in the increase of life expectancy, causes of death, and the role of cohort factors. The key question in the book is whether it is possible to project future mortality accurately, and if so, what is the best approach. This makes the book a valuable read to demographers, pension planners, actuaries, and all those interested and/or working in modelling and forecasting mortality.

Deliberately Divided

Author : Nancy L. Segal
Publisher : Rowman & Littlefield
ISBN 13 : 1538132869
Total Pages : 521 pages
Book Rating : 4.5/5 (381 download)

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Book Synopsis Deliberately Divided by : Nancy L. Segal

Download or read book Deliberately Divided written by Nancy L. Segal and published by Rowman & Littlefield. This book was released on 2021-11-08 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 2022 Choice Reviews Outstanding Academic Title Takes the first in-depth look at the New York City adoption agency that separated twins and triplets in the 1960s, and the controversial and disturbing study that tracked the children’s development while never telling their adoptive parents that they were raising a “singleton twin.” In the early 1960s, the head of a prominent New York City Child Development Center and a psychiatrist from Columbia University launched a study designed to track the development of twins and triplets given up for adoption and raised by different families. The controversial and disturbing catch? None of the adoptive parents had been told that they were raising a twin—the study’s investigators insisted that the separation be kept secret. Here, Nancy Segal reveals the inside stories of the agency that separated the twins, and the collaborating psychiatrists who, along with their cadre of colleagues, observed the twins until they turned twelve. This study, far outside the mainstream of scientific twin research, was not widely known to scholars or the general public until it caught the attention of documentary filmmakers whose recent films, Three Identical Strangers and The Twinning Reaction,left viewers shocked, angered, saddened and wanting to know more. Interviews with colleagues, friends and family members of the agency’s psychiatric consultant and the study’s principal investigator, as well as a former agency administrator, research assistants, journalists, ethicists, attorneys, and—most importantly--the twins and their families who were unwitting participants in this controversial study, are riveting. Through records, letters and other documents, Segal further discloses the investigators’ attempts to engage other agencies in separating twins, their efforts to avoid media exposure, their worries over informed consent issues in the 1970s and the steps taken toward avoiding lawsuits while hoping to enjoy the fruits of publication. Segal's spellbinding stories of the twins’ separation, loss and reunion offers readers the behind-the-scenes details that, until now, have been lost to the archives of history.

Placental-Fetal Growth Restriction

Author : Christoph Lees
Publisher : Cambridge University Press
ISBN 13 : 1108548180
Total Pages : 300 pages
Book Rating : 4.1/5 (85 download)

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Book Synopsis Placental-Fetal Growth Restriction by : Christoph Lees

Download or read book Placental-Fetal Growth Restriction written by Christoph Lees and published by Cambridge University Press. This book was released on 2018-03-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master the effective evaluation, analysis and management of placental-fetal growth restriction (PFGR), reducing the risk of perinatal mortality and morbidity in patients worldwide. Extensively researched by international experts, this manual provides practitioners with a detailed, hands-on approach to the practical 'pearls' for direct patient management. This authoritative volume advises on matters such as the correct evaluation and management of high-risk patients in danger of PFGR through to delivery. Extensive and wide-ranging, this book is an invaluable companion to the developing research interest and clinical applications in PFGR, including developmental outcomes in early childhood. Featuring a critical evaluation of a variety of abnormal conditions, such as fetal hypoxia, which are clearly displayed through extensive illustrations. This essential toolkit ensures that practitioners of all levels can effectively limit the risk of mortality and morbidity, and reach the correct diagnosis, first-time.

Windows to the Womb

Author : David Chamberlain
Publisher : North Atlantic Books
ISBN 13 : 1583945695
Total Pages : 239 pages
Book Rating : 4.5/5 (839 download)

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Book Synopsis Windows to the Womb by : David Chamberlain

Download or read book Windows to the Womb written by David Chamberlain and published by North Atlantic Books. This book was released on 2013-01-15 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneering birth psychologist combines a lifetime’s worth of research with new findings to provide a fascinating look inside the minds of unborn children In the past, the invisible physical processes of fetal development were mysterious and largely unexplainable. But thanks to breakthroughs in embryology, interuterine photography, ultrasound, and other sensitive instruments of measurement, we can now make systematic observations inside the womb—and can see that fetuses are fully sentient, aware beings. In this new climate of appreciation for the surprising dimensions of fetal behavior, sensitivity, and intelligence, Windows to the Womb brings a host of new information to light about the transformative journey each one of us undergoes in the womb. Birth psychologist Dr. David Chamberlain describes the amazing construction of our physical bodies—the "ultimate architecture"—and draws parallels with the expansion of our minds as our brains and senses develop and grow. He also details new discoveries in embryonic and fetal research that support his own findings on the impact of the mother's emotional and physical state during pregnancy; the importance of bonding at the earliest stages; and the steps that expectant parents can take to ensure the most nurturing start in life for their children.

Medical Epigenetics

Author : Trygve Tollefsbol
Publisher : Academic Press
ISBN 13 : 0128032405
Total Pages : 944 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Medical Epigenetics by : Trygve Tollefsbol

Download or read book Medical Epigenetics written by Trygve Tollefsbol and published by Academic Press. This book was released on 2016-06-21 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine

Handbook of Famine, Starvation, and Nutrient Deprivation

Author : Victor R. Preedy
Publisher : Springer
ISBN 13 : 9783319553863
Total Pages : 0 pages
Book Rating : 4.5/5 (538 download)

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Book Synopsis Handbook of Famine, Starvation, and Nutrient Deprivation by : Victor R. Preedy

Download or read book Handbook of Famine, Starvation, and Nutrient Deprivation written by Victor R. Preedy and published by Springer. This book was released on 2019-03-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the causes and effects of nutrient deficiencies along the cell-to-communities continuum. The book is primarily concerned with a lack or deficiency of one or more micro- or macronutrients in connection with malnutrition, under nutrition, and starvation. Embedded within the deficiency states is acute restriction whereby food is withdrawn completely for short periods, as when individuals are adhering to religious requirements or undergoing surgical procedures. Further downstream is the consumption of a fraction of the normal diet, as when individuals are dieting or when there is restriction in the amount or variety of food available. The causes of such reductions in dietary intake are varied and also include the social context of poverty, financial limitations, and famine. Refugees and displaced persons may also be vulnerable to under nutrition or total starvation. Diseases may also impact on the total food consumed, such as when there are physical impediments (intestinal obstruction or dysphagia) or anorexia (induced by organic disease or as a disease process per se, ie, anorexia nervosa). This book, organized as approximately 125 chapters in 17 major sections, covers the variable manifestations of dietary restrictions on cells, whole organs, the individual, and societies.