Development Of A Fully Integrated Sample In Answer Out System For Automatic Genetic Analysis

Download Development Of A Fully Integrated Sample In Answer Out System For Automatic Genetic Analysis full books in PDF, epub, and Kindle. Read online Development Of A Fully Integrated Sample In Answer Out System For Automatic Genetic Analysis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Development of a Fully Integrated “Sample-In-Answer-Out” System for Automatic Genetic Analysis

Author : Bin Zhuang
Publisher : Springer
ISBN 13 : 9811047537
Total Pages : 131 pages
Book Rating : 4.8/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Development of a Fully Integrated “Sample-In-Answer-Out” System for Automatic Genetic Analysis by : Bin Zhuang

Download or read book Development of a Fully Integrated “Sample-In-Answer-Out” System for Automatic Genetic Analysis written by Bin Zhuang and published by Springer. This book was released on 2017-07-20 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports on the development of a fully integrated and automated microsystem consisting of low-cost, disposable plastic chips for DNA extraction and PCR amplification, combined with a reusable glass capillary array electrophoresis chip, which can be employed in a modular-based format for genetic analysis. In the thesis, DNA extraction is performed by adopting a filter paper-based method, followed by an “in-situ” PCR carried out directly in the same reaction chamber of the chip without elution. PCR products are then co-injected with sizing standards into separation channels for detection using a novel injection electrode. The entire process is automatically carried out by a custom-made compact control and detection instrument. The author thoroughly tests the system’s performance and reliability by conducting rapid genetic screening of mutations on congenital hearing loss and pharmacogenetic typing of multiple warfarin-related single-nucleotide polymorphisms. The successful development and operation of this microsystem establishes the feasibility of rapid “sample-in-answer-out” testing in routine clinical practice.

Integrated Microfluidic Bioprocessors for Infectious Disease Detection

Author : Numrin Thaitrong
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.:/5 (769 download)

DOWNLOAD NOW!

Book Synopsis Integrated Microfluidic Bioprocessors for Infectious Disease Detection by : Numrin Thaitrong

Download or read book Integrated Microfluidic Bioprocessors for Infectious Disease Detection written by Numrin Thaitrong and published by . This book was released on 2010 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of micro-Total Analysis Systems has revolutionized the world of molecular diagnostics by enabling sensitive multi-step fluidic processes to be performed and reliably integrated in a single platform. In particular, microfluidic systems now provide the tools and components to enable quantitative detection of biomarkers relevant to pathogen identification and disease characterization. In this thesis, these advances are exploited to develop an integrated microfluidic platform for automated, rapid and sensitive genetic identification of infectious food-borne bacterial and respiratory viral pathogens. My first goal was the integration of improved sample purification, preconcentration and injection technology with a polymerase chain reaction-capillary electrophoresis (PCR-CE) microdevice. By introducing an in-line affinity capture system utilizing an in situ photopolymerized oligonucleotide capture gel, double-stranded PCR amplicons generated in an integrated PCR reactor were selectively captured, purified and injected with 100% efficiency for high resolution CE separation. The superior performance of this integrated platform was demonstrated in a quantitative genetic analysis of E. coli. This integrated system exhibits a six- fold improvement in resolution of a multiplex analysis of Escherichia coli O157/E. coli K12 and is able to detect E. coli O157 in a 500-fold higher background of E. coli K12. To enable the parallel detection of multiple infectious pathogens, an improved purification method relying on biotin-streptavidin interaction was developed for universal product capture. This technique has the advantage of eliminating the complications associated with designing sequence-specific oligonucleotide capture probes for multiple targets. This process was integrated into a new 4-unit array PCR-CE microchip designed for automated product amplification, capture, and analysis. Coupled with a portable laser-induced fluorescence rotary scanner, the system can simultaneously detect as few as ten copies per reactor of influenza A & B, human metapneumovirus (hMPV), and coronavirus samples from cloned plasmid standards within 2.5 hours. Furthermore, the ability of the system to process RNA samples was demonstrated by performing RT-PCR analyses of an influenza B/hMPV co-infection model case, with respective detection limits of 50 and 100 copies/reactor. This thesis concludes with a discussion of proposed methods for nucleic acid isolation from biological samples that will provide a complete sample-in to answer-out diagnostic device and method for pathogen detection. When fully developed, this technology will be a significant advancement in infectious disease detection and surveillance both inside and outside clinical settings.

Microfluidic Devices for Biomedical Applications

Author : Xiujun (James) Li
Publisher : Woodhead Publishing
ISBN 13 : 0128227559
Total Pages : 724 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!

Book Synopsis Microfluidic Devices for Biomedical Applications by : Xiujun (James) Li

Download or read book Microfluidic Devices for Biomedical Applications written by Xiujun (James) Li and published by Woodhead Publishing. This book was released on 2021-08-05 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic Devices for Biomedical Applications, Second Edition provides updated coverage on the fundamentals of microfluidics, while also exploring a wide range of medical applications. Chapters review materials and methods, microfluidic actuation mechanisms, recent research on droplet microfluidics, applications in drug discovery and controlled-delivery, including micro needles, consider applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds, and cover the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. This book is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. - Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores a wide range of medical applications - Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies - Details applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and its role in developing tissue scaffolds, and stem cell engineering

Device Engineering for Infectious Disease Diagnosis Using Isothermal DNA Amplification and Lateral Flow Detection

Author : Kristina Rosko
Publisher :
ISBN 13 :
Total Pages : 118 pages
Book Rating : 4.:/5 (951 download)

DOWNLOAD NOW!

Book Synopsis Device Engineering for Infectious Disease Diagnosis Using Isothermal DNA Amplification and Lateral Flow Detection by : Kristina Rosko

Download or read book Device Engineering for Infectious Disease Diagnosis Using Isothermal DNA Amplification and Lateral Flow Detection written by Kristina Rosko and published by . This book was released on 2013 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies that enable infectious diseases diagnosis in low-resource settings could greatly facilitate effective treatment and containment of such diseases. Nucleic acid amplification testing can be used to identify pathogens, but typically requires highly-trained personnel and large, expensive lab equipment, neither of which is available in low-resource settings. Our overall goal is to develop a portable diagnostic system that utilizes a low-cost, disposable, mesofluidic cartridge and a handheld electronics unit to perform fully-integrated nucleic acid testing at the point of care in low-resource settings. As a first step toward this goal, we developed a subunit to execute isothermal nucleic acid amplification coupled with lateral flow detection, in parallel with the development of a sample preparation subunit by our collaborators at Claremont BioSolutions. Fluid handling inside the amplification and detection cartridge is facilitated through one-way passive valves, flexible pouches, and electrolysis-driven pumps, which promotes a compact and inexpensive instrument design. The closed-system disposable prevents workspace amplicon contamination. The cartridge design is based on standard, scalable manufacturing techniques, such as injection molding. Using an initial prototype system, we demonstrated detection of purified Mycobacterium tuberculosis genomic DNA. We then developed a refined amplification and detection cartridge in conjunction with an improved portable instrument, which automates pumping, heating, and timing, using a design format compatible with eventual integration with the sample preparation subunit. This refined cartridge incorporates a novel, inexpensive, stand-alone, passive valve, smaller, integrated pump components, a more complex injection molded polycarbonate cartridge core piece, and enhanced lateral flow chambers to improve visual detection. The independent valve component can be tailored for a variety of fluidic systems. We demonstrated appropriate fluidic and thermal control, and successful isothermal nucleic acid amplification within this refined amplification and detection subunit. We have developed a separate fluidic module for master-mix reagent storage and reconstitution that is designed to act as the interface between the amplification and detection subunit and the upstream sample preparation subunit. We envision that the merger of these two subunits into a fully-integrated cartridge will enable user-friendly, automated sample-in to answer-out diagnosis of infectious diseases in primary care settings of low-resource countries with high disease burden.

Forensic DNA Analysis

Author : Jaiprakash G. Shewale
Publisher : CRC Press
ISBN 13 : 1466571365
Total Pages : 445 pages
Book Rating : 4.4/5 (665 download)

DOWNLOAD NOW!

Book Synopsis Forensic DNA Analysis by : Jaiprakash G. Shewale

Download or read book Forensic DNA Analysis written by Jaiprakash G. Shewale and published by CRC Press. This book was released on 2013-08-19 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing, forensic casework, family lineage studies, identification of human remains, and DNA databasing. Forensic DNA Analysis:

Tietz Textbook of Laboratory Medicine - E-Book

Author : Nader Rifai
Publisher : Elsevier Health Sciences
ISBN 13 : 0323834671
Total Pages : 4232 pages
Book Rating : 4.3/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Tietz Textbook of Laboratory Medicine - E-Book by : Nader Rifai

Download or read book Tietz Textbook of Laboratory Medicine - E-Book written by Nader Rifai and published by Elsevier Health Sciences. This book was released on 2022-02-03 with total page 4232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. - Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. - Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. - Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. - Analytical criteria focus on the medical usefulness of laboratory procedures. - Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. - Elsevier eBooks+ provides the entire text as a fully searchable eBook, and includes animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more, all included with print purchase. - NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. - NEW! Updated, peer-reviewed content provides the most current information possible. - NEW! The largest-ever compilation of clinical cases in laboratory medicine is included with print purchase on Elsevier eBooks+. - NEW! Over 100 adaptive learning courses included with print purchase on Elsevier eBooks+ offer the opportunity for personalized education.

Integrated Biochips for DNA Analysis

Author : Robin Liu
Publisher : Springer Science & Business Media
ISBN 13 : 0387767592
Total Pages : 216 pages
Book Rating : 4.3/5 (877 download)

DOWNLOAD NOW!

Book Synopsis Integrated Biochips for DNA Analysis by : Robin Liu

Download or read book Integrated Biochips for DNA Analysis written by Robin Liu and published by Springer Science & Business Media. This book was released on 2008-12-03 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to provide up-to-date coverage of some of the emerging developments in the field of integrated DNA biochips. It will prove a useful source of information for researchers in the field and for those who are just entering the field of biochip research.

Integrated Microsystems

Author : Krzysztof Iniewski
Publisher : CRC Press
ISBN 13 : 1439836213
Total Pages : 760 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Integrated Microsystems by : Krzysztof Iniewski

Download or read book Integrated Microsystems written by Krzysztof Iniewski and published by CRC Press. This book was released on 2017-12-19 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications. Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized design and fabrication of these intelligent miniaturized devices and systems. Composed of contributions from experts in academia and industry around the world, this reference covers processes compatible with CMOS integrated circuits, which combine computation, communications, sensing, and actuation capabilities. Light on math and physics, with a greater emphasis on microsystem design and configuration and electrical engineering, this book is organized in three sections—Microelectronics and Biosystems, Photonics and Imaging, and Biotechnology and MEMs. It addresses key topics, including physical and chemical sensing, imaging, smart actuation, and data fusion and management. Using tables, figures, and equations to help illustrate concepts, contributors examine and explain the potential of emerging applications for areas including biology, nanotechnology, micro-electromechanical systems (MEMS), microfluidics, and photonics.

Molecular Diagnostics

Author : George P. Patrinos
Publisher : Academic Press
ISBN 13 : 0128029889
Total Pages : 526 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Molecular Diagnostics by : George P. Patrinos

Download or read book Molecular Diagnostics written by George P. Patrinos and published by Academic Press. This book was released on 2016-10-27 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management. - Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories - Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression - Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Author : Carl A. Burtis
Publisher : Elsevier Health Sciences
ISBN 13 : 1455759422
Total Pages : 2259 pages
Book Rating : 4.4/5 (557 download)

DOWNLOAD NOW!

Book Synopsis Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book by : Carl A. Burtis

Download or read book Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book written by Carl A. Burtis and published by Elsevier Health Sciences. This book was released on 2011-12-16 with total page 2259 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine expanded chapters that focus on emerging issues and techniques, written by experts in field, including Y.M. Dennis Lo, Rossa W.K. Chiu, Carl Wittwer, Noriko Kusukawa, Cindy Vnencak-Jones, Thomas Williams, Victor Weedn, Malek Kamoun, Howard Baum, Angela Caliendo, Aaron Bossler, Gwendolyn McMillin, and Kojo S.J. Elenitoba-Johnson. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.

Electromigration Techniques

Author : Boguslaw Buszewski
Publisher : Springer Science & Business Media
ISBN 13 : 3642350437
Total Pages : 368 pages
Book Rating : 4.6/5 (423 download)

DOWNLOAD NOW!

Book Synopsis Electromigration Techniques by : Boguslaw Buszewski

Download or read book Electromigration Techniques written by Boguslaw Buszewski and published by Springer Science & Business Media. This book was released on 2013-04-23 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides the broad knowledge on electromigration techniques including: theory of CE, description of instrumentation, theory and practice in micellar electrokinetic chromatography, isotachophoresis, capillary isoelectric focusing, capillary and planar electrochromatography (including description of instrumentation and packed and monolithic column preparation), 2D-gel electrophoresis (including sample preparation) and lab-on-a-chip systems. The book also provides the most recent examples of applications including food, environmental, pharmaceutical analysis as well as proteomics.

Emerging Areas in Bioengineering

Author : Ho Nam Chang
Publisher : John Wiley & Sons
ISBN 13 : 3527340882
Total Pages : 898 pages
Book Rating : 4.5/5 (273 download)

DOWNLOAD NOW!

Book Synopsis Emerging Areas in Bioengineering by : Ho Nam Chang

Download or read book Emerging Areas in Bioengineering written by Ho Nam Chang and published by John Wiley & Sons. This book was released on 2018-03-12 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt: With more than 40 contributions from expert authors, this is an extensive overview of all important research topics in the field of bioengineering, including metabolic engineering, biotransformations and biomedical applications. Alongside several chapters dealing with biotransformations and biocatalysis, a whole section is devoted to biofuels and the utilization of biomass. Current perspectives on synthetic biology and metabolic engineering approaches are presented, involving such example organisms as Escherichia coli and Corynebacterium glutamicum, while a further section covers topics in biomedical engineering including drug delivery systems and biopharmaceuticals. The book concludes with chapters on computer-aided bioprocess engineering and systems biology. This is a part of the Advanced Biotechnology book series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question. Invaluable reading for biotechnologists and bioengineers, as well as those working in the chemical and pharmaceutical industries. Advanced Biotechnology Biotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang-Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.

Analytical Separation Science, 5 Volume Set

Author : Jared Anderson
Publisher : John Wiley & Sons
ISBN 13 : 3527333746
Total Pages : 2148 pages
Book Rating : 4.5/5 (273 download)

DOWNLOAD NOW!

Book Synopsis Analytical Separation Science, 5 Volume Set by : Jared Anderson

Download or read book Analytical Separation Science, 5 Volume Set written by Jared Anderson and published by John Wiley & Sons. This book was released on 2016-02-29 with total page 2148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endlich ein Forschungsleitfaden für Wissenschaftler des Fachgebiets, die neue Methoden entwickeln oder einsetzen. Dieses Handbuch umfasst fünf thematische Bände und bietet damit einen umfassenden Überblick über das Fachgebiet. Erläutert werden Grundlagen, die Methodenentwicklung und hochkarätige Anwendungen für alle wichtigen Analyseverfahren, darunter chromatische Verfahren, Techniken in den Bereichen Elektromigration und Membranen. Dieses Referenzwerk umfasst ein breites Spektrum und legt den Schwerpunkt auf Entwicklungen für die Zukunft. Damit ist es ein Muss für Forscher und eine wertvolle Wissensquelle für Studenten im Hauptstudium und Studienabsolventen.

Advances in Clinical Chemistry

Author : Gregory S. Makowski
Publisher : Academic Press
ISBN 13 : 0128215615
Total Pages : 302 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!

Book Synopsis Advances in Clinical Chemistry by : Gregory S. Makowski

Download or read book Advances in Clinical Chemistry written by Gregory S. Makowski and published by Academic Press. This book was released on 2020-09-20 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Clinical Chemistry, Volume 99, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this release including chapters on Extracellular vesicle associated proteins as potential biomarkers, Molecular and non-molecular approaches to etiologic diagnosis of gastroenteritis, Circular RNAs and cancer: Opportunities and challenges, Mass spectrometry-based metabolomics for an in-depth questioning of human health, Application of microfluidic technology in cancer research and therapy, Advances in aptasensor technology, and much more. - Covers the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians and research scientists - Provides the international benchmark for novel analytical approaches in the clinical laboratory

Sensors

Author : Bruno Andò
Publisher : Springer
ISBN 13 : 303004324X
Total Pages : 620 pages
Book Rating : 4.0/5 (3 download)

DOWNLOAD NOW!

Book Synopsis Sensors by : Bruno Andò

Download or read book Sensors written by Bruno Andò and published by Springer. This book was released on 2019-01-17 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers the best papers presented at the Fourth Italian National Conference on Sensors, held in Catania, Italy, from 21 to 23 February 2018. The book represents an invaluable and up-to-the-minute tool, providing an essential overview of recent findings, strategies and new directions in the area of sensor research. Further, it addresses various aspects based on the development of new chemical, physical or biological sensors, assembling and characterization, signal treatment and data handling. Lastly, the book applies electrochemical, optical and other detection strategies to relevant issues in the food and clinical environmental areas, as well as industry-oriented applications.

Antimicrobial Drug Resistance

Author : Douglas L. Mayers
Publisher : Springer
ISBN 13 : 3319472666
Total Pages : 846 pages
Book Rating : 4.3/5 (194 download)

DOWNLOAD NOW!

Book Synopsis Antimicrobial Drug Resistance by : Douglas L. Mayers

Download or read book Antimicrobial Drug Resistance written by Douglas L. Mayers and published by Springer. This book was released on 2017-06-19 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.

Bioremediation Technology

Author : M. H. Fulekar
Publisher : Springer Science & Business Media
ISBN 13 : 9048136784
Total Pages : 391 pages
Book Rating : 4.0/5 (481 download)

DOWNLOAD NOW!

Book Synopsis Bioremediation Technology by : M. H. Fulekar

Download or read book Bioremediation Technology written by M. H. Fulekar and published by Springer Science & Business Media. This book was released on 2012-03-05 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental pollutants have become a major global concern. The modern growth of industrialization, urbanization, modern agricultural development and energy generation have resulted in indiscriminate exploitation of natural resources for fulfilling the human desires and needs, which have contributed in disturbing the ecological balance on which the quality of environment depends. The modern technological advancements in chemical processes/operations have been raised to new products and also new pollutants in abundant level which are above the self cleaning capacity of the environment. One of the major issues in present times is the threat to human lives, due to the progressive deterioration of the environment. This book discusses bioremediation technology-based remediation to restore contaminated sites and protect the environment. It studies the opportunities for more efficient biological processes in molecular biology and ecology. Notable accomplishments of these studies include the cleaning up of polluted water and contaminated land. The book includes invited papers by eminent contributors who provide cost-effective bioremediation strategies to immobilize contaminants for cleanup of environment. The book is directed towards postgraduate students in biotechnology/life sciences/environmental sciences/biosciences and researchers in universities and research institutes and industries.