Developing Novel Drug Delivery Systems For Platinum Based Anticancer Drugs Using Coordination Driven Self Assembly

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Principles and Applications of Aggregation-Induced Emission

Author : Youhong Tang
Publisher : Springer
ISBN 13 : 3319990373
Total Pages : 520 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Principles and Applications of Aggregation-Induced Emission by : Youhong Tang

Download or read book Principles and Applications of Aggregation-Induced Emission written by Youhong Tang and published by Springer. This book was released on 2018-10-09 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the aggregation-induced emission (AIE) effect, which has opened new avenues for the development of advanced luminogenic materials in the aggregate or solid state. By enabling light emission in the practically useful solid state, AIE has the potential to significantly expand the technological applications of luminescent materials. This book addresses principles, methods, and applications of AIEs, offering a new platform for the investigation of light-emitting processes from luminogen aggregates. Applications of AIE include biomedical diagnostics, sensor materials, and optoelectronic devices, among others, and are described in detail within the book. The development of a new generation of AIEgens, a deep understanding of the AIE mechanism(s), and the exploration of advanced technological applications will enable this exciting field to develop further. Headed by the pioneering researcher who started the field, Professor Ben Zhong Tang, this book combines both principles and applications and brings together global researchers in the field to report the progress, current challenges, and potential breakthroughs that may be accomplished in the near future. Provides an authoritative account of the fundamentals, properties, and potential of AIE by the pioneer of this active, highly-researched field; Highlights technological applications of AIE spanning biomedicine, sensor materials, and optoelectronics, among others; Presents a comprehensive view on challenges in the further development of AIE and derived technologies.

Bioinorganic Chemistry

Author : Rosette M. Roat-Malone
Publisher : John Wiley & Sons
ISBN 13 : 1119535212
Total Pages : 350 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Bioinorganic Chemistry by : Rosette M. Roat-Malone

Download or read book Bioinorganic Chemistry written by Rosette M. Roat-Malone and published by John Wiley & Sons. This book was released on 2020-03-17 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces students to the basics of bioinorganic chemistry This book provides the fundamentals for inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. It provides essential background material, followed by detailed information on selected topics, to give readers the background, tools, and skills they need to research and study bioinorganic topics of interest to them. To reflect current practices and needs, instrumental methods and techniques are referred to and mixed in throughout the book. Bioinorganic Chemistry: A Short Course, Third Edition begins with a chapter on Inorganic Chemistry and Biochemistry Essentials. It then continues with chapters on: Computer Hardware, Software, and Computational Chemistry Methods; Important Metal Centers in Proteins; Myoglobins, Hemoglobins, Superoxide Dismutases, Nitrogenases, Hydrogenases, Carbonic Anhydrases, and Nitrogen Cycle Enzymes. The book concludes with chapters on Nanobioinorganic Chemistry and Metals in Medicine. Readers are also offered end-of-section summaries, conclusions, and thought problems. Reduces size of the text from previous edition to match the first, keeping it appropriate for a one-semester course Offers primers and background materials to help students feel comfortable with research-level bioinorganic chemistry Emphasizes select and diverse topics using extensive references from current scientific literature, with more emphasis on molecular biology in the biochemistry section, leading to a discussion of CRISPR technology Adds new chapters on hydrogenases, carbonic anhydrases, and nitrogen cycle enzymes, along with a separate chapter on nanobioinorganic chemistry Features expanded coverage of computer hardware and software, metalloenzymes, and metals in medicines Supplemented with a companion website for students and instructors featuring Powerpoint and JPEG figures and tables, arranged by chapter Appropriate for one-semester bioinorganic chemistry courses, Bioinorganic Chemistry: A Short Course, Third Edition is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers in need of a general introduction to the subject, as well as chemists requiring an accessible reference.

Metal-based Anticancer Agents

Author : Angela Casini
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017676
Total Pages : 370 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Metal-based Anticancer Agents by : Angela Casini

Download or read book Metal-based Anticancer Agents written by Angela Casini and published by Royal Society of Chemistry. This book was released on 2019-04-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.

Supramolecular Metal-Based Entities for Biomedical and Biological Applications

Author : Angela Casini
Publisher : Frontiers Media SA
ISBN 13 : 2889458997
Total Pages : 119 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Supramolecular Metal-Based Entities for Biomedical and Biological Applications by : Angela Casini

Download or read book Supramolecular Metal-Based Entities for Biomedical and Biological Applications written by Angela Casini and published by Frontiers Media SA. This book was released on 2019-07-19 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in the discovery of metal supramolecular complexes, mainly formed by the self-assembly of inorganic metal compounds with either inorganic or organic molecules via coordination (or organometallic) bonds, is a rapidly developing and newly rising highlight interdisciplinary field. This Reseach Topic is aimed at providing representative examples of supramolecular metal-based entities for different biological and biomedical applications.

Nanomaterials for Cancer Therapy

Author : Challa S. S. R. Kumar
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nanomaterials for Cancer Therapy by : Challa S. S. R. Kumar

Download or read book Nanomaterials for Cancer Therapy written by Challa S. S. R. Kumar and published by Wiley-VCH. This book was released on 2006-07-24 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive overview on nanotechnological approaches to cancer therapy brings together therapeutic oncology and nanotechnology, showing the various strategic approaches to selectively eliminating cancerous cells without damaging the surrounding healthy tissue. The strategies covered include magnetic, optical, microwave and neutron absorption techniques, nanocapsules for active agents, nanoparticles as active agents, and active and passive targeting, while also dealing with fundamental aspects of how nanoparticles cross biological barriers. A valuable single source gathering the many articles published in specialized journals often difficult to locate for members of the other disciplines involved.

Bioinorganic Medicinal Chemistry

Author : Enzo Alessio
Publisher : John Wiley & Sons
ISBN 13 : 352763312X
Total Pages : 625 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bioinorganic Medicinal Chemistry by : Enzo Alessio

Download or read book Bioinorganic Medicinal Chemistry written by Enzo Alessio and published by John Wiley & Sons. This book was released on 2011-02-25 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.

Engineering Polymer Systems for Improved Drug Delivery

Author : Rebecca A. Bader
Publisher : John Wiley & Sons
ISBN 13 : 1118747801
Total Pages : 395 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Engineering Polymer Systems for Improved Drug Delivery by : Rebecca A. Bader

Download or read book Engineering Polymer Systems for Improved Drug Delivery written by Rebecca A. Bader and published by John Wiley & Sons. This book was released on 2014-01-17 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Nanostructures for Oral Medicine

Author : Ecaterina Andronescu
Publisher : Elsevier
ISBN 13 : 0323477216
Total Pages : 1036 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanostructures for Oral Medicine by : Ecaterina Andronescu

Download or read book Nanostructures for Oral Medicine written by Ecaterina Andronescu and published by Elsevier. This book was released on 2017-04-11 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. - Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied - Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine - Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

Supramolecular Nanomaterials for Engineering, Drug Delivery, and Medical Applications

Author : Yohann Corvis
Publisher : Frontiers Media SA
ISBN 13 : 2889664120
Total Pages : 107 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Supramolecular Nanomaterials for Engineering, Drug Delivery, and Medical Applications by : Yohann Corvis

Download or read book Supramolecular Nanomaterials for Engineering, Drug Delivery, and Medical Applications written by Yohann Corvis and published by Frontiers Media SA. This book was released on 2021-01-21 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Healthcare Materials

Author : Ashutosh Tiwari
Publisher : John Wiley & Sons
ISBN 13 : 1118773683
Total Pages : 421 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Advanced Healthcare Materials by : Ashutosh Tiwari

Download or read book Advanced Healthcare Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-05-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Author : Kamal Dua
Publisher : Academic Press
ISBN 13 : 0128208880
Total Pages : 620 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems by : Kamal Dua

Download or read book Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems written by Kamal Dua and published by Academic Press. This book was released on 2020-08-04 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. - Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases - Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases - Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Metallosurfactants

Author : Surinder K. Mehta
Publisher : John Wiley & Sons
ISBN 13 : 3527348689
Total Pages : 292 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Metallosurfactants by : Surinder K. Mehta

Download or read book Metallosurfactants written by Surinder K. Mehta and published by John Wiley & Sons. This book was released on 2022-05-31 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallosurfactants Provides up-to-date coverage of the synthesis, properties, and applications of metallosurfactants Metallosurfactants: From Fundamentals to Catalytic and Biomedical Applications is a thorough introduction to amphiphilic compounds that allow to incorporate metal ions in the surfactant system. This comprehensive reference and guide describes the fundamentals of metal surfactant complexes, highlights recent advances in the field, and explores current and future applications and research areas. Gradually progressing from basic to advanced topics, the authors first explain the classification and characterization of metallosurfactants before delving into more complex concepts and various catalytic, sensing, and biomedical applications. The book begins with coverage of the synthesis of metallosurfactants and their surface, interfacial, and aggregation behavior. Subsequent chapters discuss applications of metallosurfactants in areas such as drug delivery, molecular machines, transfection, nanoparticle synthesis, and carbon monoxide-releasing molecules (CORMs). Other topics include the use of metallosurfactants as catalysts in organic reactions, and as anticancer and antimicrobial agents in drug delivery and formulation. This unique reference Provides an overview of the structure-function relationship, synthesis methods, and characterization of metallosurfactants Reviews current trends in metallosurfactant development and research Examines the use of metallosurfactants in a wide range of reactions, including esterolytic reactions and hydrogen generation Discusses advanced applications of metallosurfactants, e.g. as nanoreactors for nanoparticle synthesis, non-viral transfection vectors, and sensors Metallosurfactants: From Fundamentals to Catalytic and Biomedical Applications is an excellent introduction to the growing field of metallosurfactant chemistry as well as a concise, highly useful reference for researchers and scientists in both academia and industry.

Cancer Theranostics

Author : Xiaoyuan Chen
Publisher : Academic Press
ISBN 13 : 0124078842
Total Pages : 543 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Cancer Theranostics by : Xiaoyuan Chen

Download or read book Cancer Theranostics written by Xiaoyuan Chen and published by Academic Press. This book was released on 2014-03-20 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. - Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy - Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine - Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management

Innovations for Next-Generation Antibody-Drug Conjugates

Author : Marc Damelin
Publisher : Springer
ISBN 13 : 3319781545
Total Pages : 358 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Innovations for Next-Generation Antibody-Drug Conjugates by : Marc Damelin

Download or read book Innovations for Next-Generation Antibody-Drug Conjugates written by Marc Damelin and published by Springer. This book was released on 2018-05-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128163674
Total Pages : 352 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by : Prashant Kesharwani

Download or read book Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-01-26 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. - Provides an overview of an array of nanotechnology-based drug delivery systems - Examines the design, synthesis and application of different nanocarriers in drug and gene delivery - Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Concepts and Models in Bioinorganic Chemistry

Author : Heinz-Bernhard Kraatz
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Concepts and Models in Bioinorganic Chemistry by : Heinz-Bernhard Kraatz

Download or read book Concepts and Models in Bioinorganic Chemistry written by Heinz-Bernhard Kraatz and published by Wiley-VCH. This book was released on 2006-07-21 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Destined to set the standard, this book meets the need for a didactic textbook focusing on the role of model systems in bioinorganic chemistry. The first part features concepts in bioinorganic chemistry such as electron transfer, medicinal inorganic chemistry, bioorganometallics and metal DNA complexes, while the second part presents inorganic model chemistry on metallo-enzymes, organized by metal ion. Experts in the pertinent fields provide a didactically well-organized background on relevant biological systems, as well as on their structural, functional and spectroscopic properties. All chapters are similarly structured, each one beginning with a timeline featuring the most important historical facts on the subject, followed by a table of the most significant enzymes. The authors also summarize key developments and open questions within the respective model systems. This book is aimed at senior undergraduate and graduate students in chemistry, biochemistry, life science and related fields.

Metal-Organic Frameworks for Biomedical Applications

Author : Masoud Mozafari
Publisher : Woodhead Publishing
ISBN 13 : 0128169842
Total Pages : 584 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Metal-Organic Frameworks for Biomedical Applications by : Masoud Mozafari

Download or read book Metal-Organic Frameworks for Biomedical Applications written by Masoud Mozafari and published by Woodhead Publishing. This book was released on 2020-03-03 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-Organic Frameworks for Biomedical Applications is a comprehensive, authoritative reference that offers a substantial and complete treatment of published results that have yet to be critically reviewed. It offers a summary of current research and provides in-depth understanding of the role of metal-organic frameworks in biomedical engineering. The title consists of twenty-two chapters presented by leading international researchers in the field. Chapters are arranged by target-application in biomedical engineering, allowing medical and pharmaceutic specialists to translate current materials and engineering science on metal-organic frameworks into their work.