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Bioinorganic Medicinal Chemistry
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Book Synopsis Bioinorganic Medicinal Chemistry by : Enzo Alessio
Download or read book Bioinorganic Medicinal Chemistry written by Enzo Alessio and published by John Wiley & Sons. This book was released on 2011-02-25 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.
Book Synopsis Medicinal and Biological Inorganic Chemistry by : Ajay Kumar Goswami
Download or read book Medicinal and Biological Inorganic Chemistry written by Ajay Kumar Goswami and published by Walter de Gruyter GmbH & Co KG. This book was released on 2022-01-19 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a detailed state-of-the-art overview of inorganic chemistry applied to medicinal chemistry and biology. It covers the newly emerging field of metals in medicine and the future of medicinal inorganic chemistry. It is an essential reading for every researcher and student in medicinal and bioinorganic chemistry.
Book Synopsis Biological Inorganic Chemistry by : Ivano Bertini
Download or read book Biological Inorganic Chemistry written by Ivano Bertini and published by University Science Books. This book was released on 2007 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.
Book Synopsis Bioinorganic Medicinal Chemistry by : Supuran
Download or read book Bioinorganic Medicinal Chemistry written by Supuran and published by . This book was released on 2012-09-21 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, with an organization based on the periodic table and the relevance of different chemical elements for life processes, offers a general reference and textbook on bioinorganic medicinal chemistry. Following an introductory chapter overview of bioinorganic chemistry comes a section on the essential bioinorganic systems of hydrogen, oxygen, and gases; and their role in disease and drug targeting. The next 13 chapters cover the classes of bioinorganic drugs and new developments in drug design for new therapeutic agents. Two following sections discuss the metalloprotein and nucleic acid targets with their potential medicinal chemistry applications. The final section addresses toxicity issues of bioinorganic drugs, which all medicinal chemists need to know in order to effectively design new drugs.
Book Synopsis Bioinorganic Chemistry by : Rosette M. Roat-Malone
Download or read book Bioinorganic Chemistry written by Rosette M. Roat-Malone and published by John Wiley & Sons. This book was released on 2007-10-05 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. Rather than striving to provide a broad overview of the whole, rapidly expanding field, this resource provides essential background material, followed by detailed information on selected topics. The goal is to give readers the background, tools, and skills to research and study bioinorganic topics of special interest to them. This extensively updated premier reference and text: Presents review chapters on the essentials of inorganic chemistry and biochemistry Includes up-to-date information on instrumental and analytical techniques and computer-aided modeling and visualization programs Familiarizes readers with the primary literature sources and online resources Includes detailed coverage of Group 1 and 2 metal ions, concentrating on biological molecules that feature sodium, potassium, magnesium, and calcium ions Describes proteins and enzymes with iron-containing porphyrin ligand systems-myoglobin, hemoglobin, and the ubiquitous cytochrome metalloenzymes-and the non-heme, iron-containing proteins aconitase and methane monooxygenase Appropriate for one-semester bioinorganic chemistry courses for chemistry, biochemistry, and biology majors, this text is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers who need a general introduction to bioinorganic chemistry, as well as chemists who want an accessible desk reference.
Book Synopsis Bioinorganic Chemistry by : Ei-ichiro Ochiai
Download or read book Bioinorganic Chemistry written by Ei-ichiro Ochiai and published by Academic Press. This book was released on 2008 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the chemistry of living processes – biochemistry – has traditionally centered on the behavior of organic chemical compounds in water, the principle solvent in all cells. Organic compounds and water account for 99 % of the matter in living systems. Some 20 inorganic elements are also essential for life, and they are found in similar amounts in most living systems. Bioinorganic Chemistry is essentially the border between inorganic chemistry and biology. The overall purpose of bioinorganic research is to study the relationship between inorganic metal ions such as copper and iron, and biologically specific macromolecules, experimentally as well as theoretically. The importance of inorganic chemistry in biology, especially metal ion coordination, has gained considerable attention during the last decade. The discoveries of the roles of metal ions and metalloproteins in health and disease through genetic and biochemical studies have drawn the attention of both inorganic chemists and molecular and cell biologists. Bioinorganic courses deal with the specific properties of metal ions as expressed in the functioning of biochemical systems, with the objective to deepen student insight into the chemical behaviour of metal ions in biological systems. Ochiai is generally considered the father of the discipline. When first published in 1977, the very successful first edition provided a clear and concise introduction to the brand new field of bioinorganic chemistry. • Provides the streamlined coverage appropriate for one-semester courses or independent study, with all of the necessary but none of the excessive information • Prepares readers to move to the next level of study (whether they continue on in the field or transition to medicine/industry) • Presents concepts through extensive four-color visuals, appealing to a range of learning styles • Promotes critical thinking through open-ended questions throughout the narrative and at the end of each chapter
Book Synopsis Biological Inorganic Chemistry by : Robert R. Crichton
Download or read book Biological Inorganic Chemistry written by Robert R. Crichton and published by Elsevier. This book was released on 2007-12-11 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters
Download or read book Medicinal Chemistry written by and published by Academic Press. This book was released on 2020-02-10 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry, Volume 75, the latest release in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers that empowers readers to pursue new developments in each field. Users will find this to be a comprehensive overview of recent findings and trends from the last decade that covers various kinds of inorganic topics, from theoretical oriented supramolecular chemistry, to the quest for accurate calculations of spin states in transition metals. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Inorganic Chemistry series Includes the latest information on medicinal chemistry
Book Synopsis Bioinorganic Chemistry by : Dieter Rehder
Download or read book Bioinorganic Chemistry written by Dieter Rehder and published by OUP Oxford. This book was released on 2014-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic Chemistry provides a broad overview of this dynamic field, reviewing the key chemical elements that have important biological function, and exploring how the chemistry of these elements is central to the function of biological systems.
Book Synopsis Uses of Inorganic Chemistry in Medicine by : Nicholas P Farrell
Download or read book Uses of Inorganic Chemistry in Medicine written by Nicholas P Farrell and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline.
Book Synopsis Ligand Design in Medicinal Inorganic Chemistry by : Tim Storr
Download or read book Ligand Design in Medicinal Inorganic Chemistry written by Tim Storr and published by John Wiley & Sons. This book was released on 2014-06-12 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.
Book Synopsis Essentials of Inorganic Chemistry by : Katja A. Strohfeldt
Download or read book Essentials of Inorganic Chemistry written by Katja A. Strohfeldt and published by John Wiley & Sons. This book was released on 2015-01-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies.
Book Synopsis Frontiers in Medicinal Chemistry by : Atta-ur-Rahman
Download or read book Frontiers in Medicinal Chemistry written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2011-01-10 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. "Frontiers in Medicinal Chemistry" covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships. Medicinal chemistry as.
Book Synopsis Frontiers in Medicinal Chemistry by : Atta-ur-Rahman
Download or read book Frontiers in Medicinal Chemistry written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2016-03-22 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Medicinal Chemistry is an E-book series devoted to reviews on research topics relevant to medicinal chemistry and allied disciplines. Frontiers in Medicinal Chemistry covers developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships. This E-book series is essential for any medicinal chemist who wishes to be updated on the latest and the most important advances in the field. This volume features reviews on the following topics: • Purinergic receptors and pain • Cytochrome c – cardiolipin interactions in cells • Dipeptidyl peptidase-4 (CD26) functions and inhibition • Peptides regulating angiogenesis • Application of melanotropin ligands for the treatment of obesity and related disorders • Targeted drugs in the field of nanomedicine
Book Synopsis Bioinorganic Chemistry of Copper by : K.D. Karlin
Download or read book Bioinorganic Chemistry of Copper written by K.D. Karlin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic Chemistry of Copper focuses on the vital role of copper ions in biology, especially as an essential metalloenzyme cofactor. The book is highly interdisciplinary in its approach--the outstanding list of contributors includes coordination chemists, biochemists, biophysicists, and molecular biologists. Chapters are grouped into major areas of research interest in inorganic copper chemistry, spectroscopy, oxygen chemistry, biochemistry, and molecular biology. The book also discusses basic research of great potential importance to pharmaceutical scientists. This book is based on the first Johns Hopkins University Copper Symposium, held in August 1992. Researchers in chemistry, biochemistry, molecular biology, and medicinal chemistry will find it to be an essential reference on its subject.
Book Synopsis Principles of Bioinorganic Chemistry by : Stephen J. Lippard
Download or read book Principles of Bioinorganic Chemistry written by Stephen J. Lippard and published by University Science Books. This book was released on 1994 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance.
Book Synopsis Bioinorganic Chemistry -- Inorganic Elements in the Chemistry of Life by : Wolfgang Kaim
Download or read book Bioinorganic Chemistry -- Inorganic Elements in the Chemistry of Life written by Wolfgang Kaim and published by John Wiley & Sons. This book was released on 2013-08-01 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life sciences due to its highly interdisciplinary nature. Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. The second edition of this classic text has been fully revised and updated to include new structure information, emerging developments in the field, and an increased focus on medical applications of inorganic compounds. New topics have been added including materials aspects of bioinorganic chemistry, elemental cycles, bioorganometallic chemistry, medical imaging and therapeutic advances. Topics covered include: Metals at the center of photosynthesis Uptake, transport, and storage of essential elements Catalysis through hemoproteins Biological functions of molybdenum, tungsten, vanadium and chromium Function and transport of alkaline and alkaline earth metal cations Biomineralization Biological functions of the non-metallic inorganic elements Bioinorganic chemistry of toxic metals Biochemical behavior of radionuclides and medical imaging using inorganic compounds Chemotherapy involving non-essential elements This full color text provides a concise and comprehensive review of bioinorganic chemistry for advanced students of chemistry, biochemistry, biology, medicine and environmental science.
