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Adverse Effects of Vaccines

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309214351
Total Pages : 894 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Adverse Effects of Vaccines by : Institute of Medicine

Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines

Author : National Academy of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309089159
Total Pages : pages
Book Rating : 4.0/5 (891 download)

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Book Synopsis Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines by : National Academy of Medicine

Download or read book Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines written by National Academy of Medicine and published by National Academies Press. This book was released on 2021-12-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Influenza viruses, both seasonal and pandemic, have the potential to disrupt the health and well-being of populations around the world. The global response to the COVID-19 pandemic and prior public health emergencies of international concern illustrate the importance of global preparedness and coordination among governments, academia, scientists, policy makers, nongovernmental organizations, the private sector, and the public to address the threat of pandemic influenza. These health emergencies have revealed opportunities to enhance global vaccine infrastructure, manufacturing, distribution, and administration. Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines outlines key findings and recommendations to bolster vaccine distribution, manufacturing, and supply chains for future seasonal and pandemic influenza events. This report addresses the challenges of manufacturing and distributing vaccines for both seasonal and pandemic influenza, highlighting the critical components of vaccine manufacturing and distribution and offering recommendations that would address gaps in the current global vaccine infrastructure.

The 2009 H1N1 Influenza Vaccination Campaign

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309160219
Total Pages : 140 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The 2009 H1N1 Influenza Vaccination Campaign by : Institute of Medicine

Download or read book The 2009 H1N1 Influenza Vaccination Campaign written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-22 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2009 H1N1 vaccination campaign was one of the largest public health campaigns in U.S. history, vaccinating one-quarter of the population in the first three months. The Institute of Medicine held three workshops in Raleigh, NC; Austin, TX; and Seattle, WA to learn from participants' experiences during the campaign and improve future emergency vaccination programs.

Exploring Lessons Learned from a Century of Outbreaks

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309490359
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Exploring Lessons Learned from a Century of Outbreaks by : National Academies of Sciences, Engineering, and Medicine

Download or read book Exploring Lessons Learned from a Century of Outbreaks written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-05 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: In November 2018, an ad hoc planning committee at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics. This publication summarizes the presentations and discussions from both workshops.

Vaccines for Older Adults

Author : Birgit Weinberger
Publisher : Karger Medical Scientific
ISBN 13 : 9783318066777
Total Pages : 0 pages
Book Rating : 4.0/5 (667 download)

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Book Synopsis Vaccines for Older Adults by : Birgit Weinberger

Download or read book Vaccines for Older Adults written by Birgit Weinberger and published by Karger Medical Scientific. This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many infectious diseases are more frequent and are associated with high morbidity and mortality in older adults. Vaccination is the most efficient strategy to prevent infections, and older adults are an important target population for vaccination in order to promote health in this age group. Age-related changes in the immune system as well as other factors, such as comorbidities, obesity or frailty, influence vaccine-induced immune responses in old age. Awareness that vaccines developed for children might not be optimal for adults, and particularly for the older population, has only arisen in the recent past. Vaccination against influenza, pneumococcal disease, and herpes zoster is specifically recommended for older adults in many countries, and various strategies have been pursued in order to optimize these vaccines. However, there are still many pathogens, which severely affect the older population, but for which no vaccines are currently available. Extensive research and development are ongoing to further improve existing vaccines and to design novel vaccines in order to provide protection for this vulnerable age group. In order to exploit the full protective potential of vaccines it is essential to improve vaccine uptake and overcome vaccine hesitancy by providing information and education to stakeholders, health care professionals, and the general public. This book is relevant for researchers working on age-related changes in the immune system or on vaccine development, for health care professionals treating older patients, and for the stakeholders and decision makers involved in vaccination recommendations and implementation.

Developing Flu Vaccines

Author : Michael Burgan
Publisher : Heinemann-Raintree Library
ISBN 13 : 1410939936
Total Pages : 58 pages
Book Rating : 4.4/5 (19 download)

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Book Synopsis Developing Flu Vaccines by : Michael Burgan

Download or read book Developing Flu Vaccines written by Michael Burgan and published by Heinemann-Raintree Library. This book was released on 2011-01-01 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a history of influenza, discusses how it is spread, and explains how vaccines are developed.

Influenza Vaccine: Federal Investments in Alternative Technologies and Challenges to Development and Licensure

Author : Marcia Crosse
Publisher : DIANE Publishing
ISBN 13 : 1437988296
Total Pages : 58 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Influenza Vaccine: Federal Investments in Alternative Technologies and Challenges to Development and Licensure by : Marcia Crosse

Download or read book Influenza Vaccine: Federal Investments in Alternative Technologies and Challenges to Development and Licensure written by Marcia Crosse and published by DIANE Publishing. This book was released on 2011-10-07 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Production delays for the 2009 H1N1 pandemic vaccine using the current egg-based production technology heightened interest in alternative technologies that could expand the supply or accelerate the availability of influenza vaccine. Within the federal government, the Dept. of Health and Human Services (HHS) and the Dept. of Defense (DOD) support the development of technologies that can be used in producing technologies that can be used in producing influenza vaccines. HHS’s Food and Drug Admin. (FDA) reviews licensing applications for new vaccine, and the Dept. of State is the U.S. diplomatic liaison to the international entity that declares worldwide pandemics. This report examines (1) federal funding from FY 2005 through March 2011 for alternative technologies and the status of manufacturers’ efforts, (2) challenges to development and licensure identified by stakeholders, and (3) how HHS is addressing those challenges. Tables and figures. This is a print on demand report.

Vaccines for the 21st Century

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309174985
Total Pages : 476 pages
Book Rating : 4.1/5 (749 download)

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Book Synopsis Vaccines for the 21st Century by : Institute of Medicine

Download or read book Vaccines for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2001-02-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.

Influenza and Public Health

Author : Jennifer Gunn
Publisher : Taylor & Francis
ISBN 13 : 1136532080
Total Pages : 307 pages
Book Rating : 4.1/5 (365 download)

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Book Synopsis Influenza and Public Health by : Jennifer Gunn

Download or read book Influenza and Public Health written by Jennifer Gunn and published by Taylor & Francis. This book was released on 2010-09-23 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major influenza pandemics pose a constant threat. As evidenced by recent H5N1 avian flu and novel H1N1, influenza outbreaks can come in close succession, yet differ in their transmission and impact. With accelerated levels of commercial and population mobility, new forms of flu virus can also spread across the globe with unprecedented speed. Responding quickly and adequately to each outbreak becomes imperative on the part of governments and global public health organizations, but the difficulties of doing so are legion. One tool for pandemic planning is analysis of responses to past pandemics that provide insight into productive ways forward. This book investigates past influenza pandemics in light of today's, so as to afford critical insights into possible transmission patterns, experiences, mistakes, and interventions. It explores several pandemics over the past century, from the infamous 1918 Spanish Influenza, the avian flu epidemic of 2003, and the novel H1N1 pandemic of 2009, to lesser-known outbreaks such as the 1889-90 influenza pandemic and the Hong Kong Flu of 1968. Contributors to the volume examine cases from a wide range of disciplines, including history, sociology, epidemiology, virology, geography, and public health, identifying patterns that cut across pandemics in order to guide contemporary responses to infectious outbreaks.

Options for the Control of Influenza

Author : Alan P. Kendal
Publisher :
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Options for the Control of Influenza by : Alan P. Kendal

Download or read book Options for the Control of Influenza written by Alan P. Kendal and published by . This book was released on 1986 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Vaccine Book

Author : Barry R. Bloom
Publisher : Academic Press
ISBN 13 : 012805400X
Total Pages : 664 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Vaccine Book by : Barry R. Bloom

Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy

Influenza Virus and Vaccination

Author : Marta L. DeDiego
Publisher : MDPI
ISBN 13 : 3039288172
Total Pages : 130 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Influenza Virus and Vaccination by : Marta L. DeDiego

Download or read book Influenza Virus and Vaccination written by Marta L. DeDiego and published by MDPI. This book was released on 2020-05-28 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The influenza virus poses a threat to human health and is responsible for global epidemics every year. In addition to seasonal infections, influenza can cause occasional pandemics of great consequence when novel viruses are introduced into humans. Despite the implementation of comprehensive vaccination programs, influenza viruses continue to pose an important and unpredictable global public health threat. They are one of the most significant causes of morbidity and mortality each year and have a significant economic impact. In recent years, research has been conducted to find alternative approaches to influenza vaccine development, including the generation of universal vaccines. Notably, significant progress in the field of influenza infection, transmission, and immunity have contributed to our understanding of influenza biology, and to expanding the technological approaches for the generation of more efficient strategies against influenza infections. Moreover, highly remarkable developments have been made in the implementation of new methodologies to evaluate the efficiency of vaccines and improve them for use on domestic animals such as poultry, horses, dogs or pigs. This enables us to decrease the exposure of humans to potentially pandemic viruses. The articles in this Special Issue will address the importance of influenza to human health and the advances in influenza research that have led to the development of better therapeutics and vaccination strategies.

Epidemiology and Prevention of Vaccine-preventable Diseases

Author :
Publisher :
ISBN 13 :
Total Pages : 538 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Epidemiology and Prevention of Vaccine-preventable Diseases by :

Download or read book Epidemiology and Prevention of Vaccine-preventable Diseases written by and published by . This book was released on 2000 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt:

History of Vaccine Development

Author : Stanley A. Plotkin
Publisher : Springer Science & Business Media
ISBN 13 : 1441913394
Total Pages : 349 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis History of Vaccine Development by : Stanley A. Plotkin

Download or read book History of Vaccine Development written by Stanley A. Plotkin and published by Springer Science & Business Media. This book was released on 2011-05-11 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.

Priorities for the National Vaccine Plan

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309156203
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Priorities for the National Vaccine Plan by : Institute of Medicine

Download or read book Priorities for the National Vaccine Plan written by Institute of Medicine and published by National Academies Press. This book was released on 2010-05-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccination is a fundamental component of preventive medicine and public health. The use of vaccines to prevent infectious diseases has resulted in dramatic decreases in disease, disability, and death in the United States and around the world. The current political, economic, and social environment presents both opportunities for and challenges to strengthening the U.S. system for developing, manufacturing, regulating, distributing, funding, and administering safe and effective vaccines for all people. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. The book makes recommendations about priority actions in the update to the National Vaccine Plan that are intended to achieve the objectives of disease prevention and enhancement of vaccine safety. It is centered on the plan's five goals in the areas of vaccine development, safety, communication, supply and use, and global health.

Maternal Immunization

Author : Elke Leuridan
Publisher : Academic Press
ISBN 13 : 0128145838
Total Pages : 394 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Maternal Immunization by : Elke Leuridan

Download or read book Maternal Immunization written by Elke Leuridan and published by Academic Press. This book was released on 2019-11-26 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunization during pregnancy with currently recommended vaccines prevents infection in the mother, the unborn fetus, and the young infant, and there is an increasing focus from different stakeholders to use this approach for other infections of importance to protect these vulnerable groups. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of vaccines in pregnancy, safety, immunogenicity (immunology), timing to vaccinate, repeat doses, protective effects in the mother, fetus, and infant, and public acceptance and implementation, of existing and of future vaccines. Provides an overview of a quickly evolving topic. This will benefit the reader who wishes to rapidly become informed and up-to-date with new developments in this field Suitable to a broad audience: scientific researchers, obstetricians, gynecologists, neonatologists, vaccinators, pediatricians, students, and industry. Maternal vaccination impacts a wide range of specialists Allows health care professionals/researchers to gain insight into other aspects of vaccination in pregnancy outside of their specialism Is coauthored by specialists from multiple disciplines, providing a diverse view of the subject, increasing its interest and appeal Creates awareness of the current developments in this area of medicine and of the potential of maternal vaccination to improve the health of mothers and infants worldwide

Vaccines for Pandemic Influenza

Author : Richard W Compans
Publisher : Springer
ISBN 13 : 9783540921660
Total Pages : 512 pages
Book Rating : 4.9/5 (216 download)

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Book Synopsis Vaccines for Pandemic Influenza by : Richard W Compans

Download or read book Vaccines for Pandemic Influenza written by Richard W Compans and published by Springer. This book was released on 2009-10-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans, resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have little or no antigenic relationship to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop eff- tive vaccines for pandemic influenza viruses, and to overcome the limitations inh- ent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine prod- tion, which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inac- vated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines that are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated.