Dendrimer Based Drug Delivery Systems

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Dendrimer-Based Drug Delivery Systems

Author : Yiyun Cheng
Publisher : John Wiley & Sons
ISBN 13 : 1118275225
Total Pages : 542 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Dendrimer-Based Drug Delivery Systems by : Yiyun Cheng

Download or read book Dendrimer-Based Drug Delivery Systems written by Yiyun Cheng and published by John Wiley & Sons. This book was released on 2012-05-23 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.

Dendrimer-Based Nanotherapeutics

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128212519
Total Pages : 484 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Dendrimer-Based Nanotherapeutics by : Prashant Kesharwani

Download or read book Dendrimer-Based Nanotherapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2021-04-14 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher

Dendrimers for Drug Delivery

Author : Anil K. Sharma
Publisher : CRC Press
ISBN 13 : 135136068X
Total Pages : 426 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Dendrimers for Drug Delivery by : Anil K. Sharma

Download or read book Dendrimers for Drug Delivery written by Anil K. Sharma and published by CRC Press. This book was released on 2018-07-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.

Pharmaceutical Applications of Dendrimers

Author : Abhay Singh Chauhan
Publisher : Elsevier
ISBN 13 : 9780128145272
Total Pages : 0 pages
Book Rating : 4.1/5 (452 download)

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Book Synopsis Pharmaceutical Applications of Dendrimers by : Abhay Singh Chauhan

Download or read book Pharmaceutical Applications of Dendrimers written by Abhay Singh Chauhan and published by Elsevier. This book was released on 2019-11-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery.

Dendrimers in Biomedical Applications

Author : Barbara Klajnert
Publisher : Royal Society of Chemistry
ISBN 13 : 1849736111
Total Pages : 215 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Dendrimers in Biomedical Applications by : Barbara Klajnert

Download or read book Dendrimers in Biomedical Applications written by Barbara Klajnert and published by Royal Society of Chemistry. This book was released on 2013 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide comprehensive coverage of dendrimer applications and clear indications for future research. It will appeal to chemists, biologists and materials scientists, working in both academia and industry.

Dendrimers in Nanomedicine

Author : Neelesh Kumar Mehra
Publisher : CRC Press
ISBN 13 : 1000333175
Total Pages : 401 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Dendrimers in Nanomedicine by : Neelesh Kumar Mehra

Download or read book Dendrimers in Nanomedicine written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-03-24 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.

Nanopharmaceutical Advanced Delivery Systems

Author : Vivek Dave
Publisher : John Wiley & Sons
ISBN 13 : 1119711681
Total Pages : 467 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Nanopharmaceutical Advanced Delivery Systems by : Vivek Dave

Download or read book Nanopharmaceutical Advanced Delivery Systems written by Vivek Dave and published by John Wiley & Sons. This book was released on 2020-12-29 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Hyperbranched Polydendrons

Author : Fiona L. Hatton
Publisher : Springer
ISBN 13 : 3319187538
Total Pages : 260 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Hyperbranched Polydendrons by : Fiona L. Hatton

Download or read book Hyperbranched Polydendrons written by Fiona L. Hatton and published by Springer. This book was released on 2015-05-18 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (>1,000,000 g/mol), exceptional self-assembly and encapsulation behaviour and unparalleled functionalisation capabilities, and were studied pharmacologically to determine their potential as oral nanomedicine candidates. The detailed investigation of the chemical variables involved in synthesising hyperbranched polydendrons has shown that their self-assembly and pharmacological behaviour can be turned on and off and fine-tuned by altering the composition of the materials. The permeation of the self-assembled particles through model gut epithelium suggests the potential for oral dosing of drug loaded nanomedicines that result in circulating nanoparticles – a research goal that is currently being pursued by several groups around the globe.

New Nanomaterials and Techniques for Tumor-targeted Systems

Author : Rongqin Huang
Publisher : Springer Nature
ISBN 13 : 9811551596
Total Pages : 462 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis New Nanomaterials and Techniques for Tumor-targeted Systems by : Rongqin Huang

Download or read book New Nanomaterials and Techniques for Tumor-targeted Systems written by Rongqin Huang and published by Springer Nature. This book was released on 2020-09-28 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the latest advances in nanomaterials and techniques in the field of tumor-targeted diagnosis and therapy. It provides valuable information for beginners and senior researchers, and stimulates new research directions by offering novel and provocative insights into the properties and technical principles of nanomaterials. The book systemically discusses the challenges in tumor treatment, current tumor-targeted strategies, drug-release strategies, diagnosis and therapeutic patterns, and also explores newly developed multifunctional nanomaterials and related systems.

Smart Nanomaterials in Biomedical Applications

Author : Jin-Chul Kim
Publisher : Springer Nature
ISBN 13 : 3030842622
Total Pages : 603 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Smart Nanomaterials in Biomedical Applications by : Jin-Chul Kim

Download or read book Smart Nanomaterials in Biomedical Applications written by Jin-Chul Kim and published by Springer Nature. This book was released on 2022-01-19 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

Dendrimers in Medical Science

Author : Zahoor Ahmad Parry
Publisher : CRC Press
ISBN 13 : 1315341786
Total Pages : 139 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Dendrimers in Medical Science by : Zahoor Ahmad Parry

Download or read book Dendrimers in Medical Science written by Zahoor Ahmad Parry and published by CRC Press. This book was released on 2017-05-25 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional formulations used to affect therapy or treatment of a disease state. The authors examine the potential uses of dendrimers, which have proven their capabilities in local/systemic drug delivery, physical stabilization of the drug, solubility enhancement of the poorly soluble drugs, and gene delivery.

Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery

Author : Zhongwei Gu
Publisher : John Wiley & Sons
ISBN 13 : 3527672729
Total Pages : 360 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery by : Zhongwei Gu

Download or read book Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery written by Zhongwei Gu and published by John Wiley & Sons. This book was released on 2014-12-04 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

Computational Pharmaceutics

Author : Defang Ouyang
Publisher : John Wiley & Sons
ISBN 13 : 1118573994
Total Pages : 350 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Computational Pharmaceutics by : Defang Ouyang

Download or read book Computational Pharmaceutics written by Defang Ouyang and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

Nanoengineering of Biomaterials

Author : Sougata Jana
Publisher : John Wiley & Sons
ISBN 13 : 3527349049
Total Pages : 1063 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanoengineering of Biomaterials by : Sougata Jana

Download or read book Nanoengineering of Biomaterials written by Sougata Jana and published by John Wiley & Sons. This book was released on 2022-04-18 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.

Advances in Nanomaterials for Drug Delivery

Author : Mahdi Karimi
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1681742896
Total Pages : 78 pages
Book Rating : 4.6/5 (817 download)

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Book Synopsis Advances in Nanomaterials for Drug Delivery by : Mahdi Karimi

Download or read book Advances in Nanomaterials for Drug Delivery written by Mahdi Karimi and published by Morgan & Claypool Publishers. This book was released on 2018-12-05 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery systems, gene therapy delivery, and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a magic bullet has led to much research in chemical modification to design and optimize the binding to targeted receptors. It is important to understand the precise relationship between the drug and the carrier and its ability to target specific tissues, and pathogens to make an efficient drug delivery system. This book covers advances based on different drug delivery systems: polymeric and hyper branched nanomaterials, carbon-based nanomaterials, nature-inspired nanomaterials, and pathogen-based carriers.

Dendrimers in Medicine

Author : Barbara Klajnert
Publisher :
ISBN 13 : 9781600216640
Total Pages : 0 pages
Book Rating : 4.2/5 (166 download)

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Book Synopsis Dendrimers in Medicine by : Barbara Klajnert

Download or read book Dendrimers in Medicine written by Barbara Klajnert and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dendrimer is a common name of polymers which are characterised by a specific structure, although their chemical composition can be very different. Dendrimers display several characteristics which distinguish them from linear polymers. All dendrimers are synthesised by attaching branched monomers to the central core molecule. Monomers are attached layer by layer. As a result of such a synthesis, dendrimers posses plenty of terminal, reactive groups on their surface and empty internal cavities. Both of these features can be utilised. Soon after the first synthesis in mid-1980's, dendrimers have become interesting and promising molecules for pharmaceutical and technical aims. The last years brought many new facts about dendrimers impact on biological systems. Both, general toxic studies, as well as detailed research devoted to particular cellular compounds, as DNA or lipid bilayer, were carried out. New types of dendrimers were synthesised and new applications appeared.

Pharmaceutical Applications of Dendrimers

Author : Abhay Singh Chauhan
Publisher : Elsevier
ISBN 13 : 0128145285
Total Pages : 398 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Pharmaceutical Applications of Dendrimers by : Abhay Singh Chauhan

Download or read book Pharmaceutical Applications of Dendrimers written by Abhay Singh Chauhan and published by Elsevier. This book was released on 2019-11-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems Discusses the potential of dendrimers in preformulation and formulation development Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations