Complement

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The Complement FactsBook

Author : Scott R. Barnum
Publisher : Academic Press
ISBN 13 : 0080529550
Total Pages : 237 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Complement FactsBook by : Scott R. Barnum

Download or read book The Complement FactsBook written by Scott R. Barnum and published by Academic Press. This book was released on 1999-10-28 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. Includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies Presents detailed structural information including cDNA and gene structure for all proteins Introduces complement function, simply described for each function Data is as up-to-date as possible, including unpublished work from many contributors Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, familiesEach chapter has been written by an expert in the field Data is as up-to-date as possible, including unpublished work from many contributors Entries provide information on: Alternative nomenclature, Physiochemical properties, Structure and function, Tissue distribution and regulation expression, Protein sequence/modules, Chromosomal location, Genomic structure, Database accession numbers, Deficiency and polymorphic variants, Key references

The Schur Complement and Its Applications

Author : Fuzhen Zhang
Publisher : Springer Science & Business Media
ISBN 13 : 0387242732
Total Pages : 308 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis The Schur Complement and Its Applications by : Fuzhen Zhang

Download or read book The Schur Complement and Its Applications written by Fuzhen Zhang and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the Schur complement as a rich and basic tool in mathematical research and applications and discusses many significant results that illustrate its power and fertility. Coverage includes historical development, basic properties, eigenvalue and singular value inequalities, matrix inequalities in both finite and infinite dimensional settings, closure properties, and applications in statistics, probability, and numerical analysis.

Complement

Author : Aaron Ivey
Publisher : B&H Books
ISBN 13 : 9781535996693
Total Pages : 256 pages
Book Rating : 4.9/5 (966 download)

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Book Synopsis Complement by : Aaron Ivey

Download or read book Complement written by Aaron Ivey and published by B&H Books. This book was released on 2021-04 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bestselling authors Jamie Ivey (host of the Happy Hour podcast) and Aaron Ivey write about God's design for a happy, healthy, flourishing marriage.

Verbal Complement Clauses

Author : Claudia Felser
Publisher : John Benjamins Publishing
ISBN 13 : 9789027227461
Total Pages : 302 pages
Book Rating : 4.2/5 (274 download)

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Book Synopsis Verbal Complement Clauses by : Claudia Felser

Download or read book Verbal Complement Clauses written by Claudia Felser and published by John Benjamins Publishing. This book was released on 1999-01-01 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph examines the syntax of bare infinitival and participial complements of perception verbs in English and other European languages, and investigates the general conditions under which verbal complement clauses are licensed. The introductory chapter is followed by an overview of the major syntactic and semantic characteristics of non-finite complements of perception verbs in English. The third chapter presents an analysis within the framework of Chomsky's (1995) Minimalist Program according to which event-denoting complements are minimally realised as projections of an aspectual head. In the next chapter, it is argued that verbs capable of licensing aspectual complement clauses must be able to function as a special type of control predicate, an assumption which is shown to account for a number of seemingly unrelated properties of the constructions under consideration. The final chapter examines syntactically reduced clausal complements from a cross-linguistic perspective, showing that Southern Romance languages differ from Germanic ones with respect to the availability of 'bare' aspectual complement clauses, a difference that is attributed to morphological properties of verbs in these languages.

Complement Methods and Protocols

Author : B. Paul Morgan
Publisher : Springer Science & Business Media
ISBN 13 : 159259056X
Total Pages : 268 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Complement Methods and Protocols by : B. Paul Morgan

Download or read book Complement Methods and Protocols written by B. Paul Morgan and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complement system, first described more than a century ago, was for many years the ugly duckling of the immunology world, but no more. Complement in recent years has blossomed into a fascinating and fast moving field of immediate relevance to clinical scientists in fields as diverse as transplantation biology, virology, and inflammation. Despite its emergence from the shadows, complement retains an unwarranted reputation for being “difficult.” This impression derives in large part from the superficially complicated nomenclature, a relic of the long and tortuous process of unraveling the system, of naming components in order of discovery rather than in a syst- atic manner. Once the barrier of nomenclature has been surmounted, then the true simplicity of the system becomes apparent. Complement comprises an activation system and a cytolytic system. The former has diverged to focus on complement to distinct targets—bacteria, - mune complexes, and others—so that texts now describe three activation pa- ways, closely related to one another, but each with some unique features. The cytolytic pathway is the same regardless of the activation process and kills cells by creating pores in the membrane. Complement plays an important role in killing bacteria and is essential for the proper handling of immune complexes. Problems occur when complement is activated in an inappropriate manner—the potent inflammation-inducing products of the cascade then cause unwanted tissue damage and destruction.

Complement

Author : G. E. W. Wolstenholme
Publisher : John Wiley & Sons
ISBN 13 : 0470716924
Total Pages : 418 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Complement by : G. E. W. Wolstenholme

Download or read book Complement written by G. E. W. Wolstenholme and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Serum Diagnosis by Complement-fixation

Author : John Albert Kolmer
Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.:/5 (37 download)

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Book Synopsis Serum Diagnosis by Complement-fixation by : John Albert Kolmer

Download or read book Serum Diagnosis by Complement-fixation written by John Albert Kolmer and published by . This book was released on 1928 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Complement Therapeutics

Author : John D. Lambris
Publisher : Springer Science & Business Media
ISBN 13 : 1461441188
Total Pages : 323 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Complement Therapeutics by : John D. Lambris

Download or read book Complement Therapeutics written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2012-09-19 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis. In addition, complement is often involved in adverse immune reactions to biomaterials, cell and organ transplants or drug delivery systems. Although the complement cascade with its close to 50 extracellular protein targets has long been recognized as an attractive system for therapeutic modulation, the past few years have seen a particularly strong boost in interest. Fueled by novel research insight and the marketing of the first complement-targeted drugs, a plethora of highly creative treatment approaches and potent drug candidates have recently emerged and are currently evaluated in disease models and clinical trials. The chapters in this book cover a wide range of topics related to the development of complement therapeutics, ranging from the molecular and functional description of complement targets to the presentation of novel inhibitors, improved treatment strategies as well as examples of disease models and clinical applications. The broad and up-to-date overview on a highly versatile and dynamic field renders this book an indispensable source of information for researchers and clinicians dealing with therapeutic and disease-related aspects of the human complement system.

Lattices with Unique Complements

Author : Vi_acheslav Nikolaevich Sali_
Publisher : American Mathematical Soc.
ISBN 13 : 9780821898178
Total Pages : 132 pages
Book Rating : 4.8/5 (981 download)

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Book Synopsis Lattices with Unique Complements by : Vi_acheslav Nikolaevich Sali_

Download or read book Lattices with Unique Complements written by Vi_acheslav Nikolaevich Sali_ and published by American Mathematical Soc.. This book was released on 1988-12-31 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The class of uniquely complemented lattices properly contains all Boolean lattices. However, no explicit example of a non-Boolean lattice of this class has been found. In addition, the question of whether this class contains any complete non-Boolean lattices remains unanswered. This book focuses on these classical problems of lattice theory and the various attempts to solve them. Requiring no specialized knowledge, the book is directed at researchers and students interested in general algebra and mathematical logic.

Current Challenges in Complement Diagnostics

Author : Erik J.M. Toonen
Publisher : Frontiers Media SA
ISBN 13 : 2832540880
Total Pages : 364 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Current Challenges in Complement Diagnostics by : Erik J.M. Toonen

Download or read book Current Challenges in Complement Diagnostics written by Erik J.M. Toonen and published by Frontiers Media SA. This book was released on 2023-12-14 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complement system is an important innate immune surveillance network that has a key role in protecting our bodies against pathogens and other threats. It is a highly complex system consisting of approximately 50 soluble and cell surface-bound proteins that interact to eliminate danger signals. These signals include factors such as invading microorganisms, necrotic cells, and immune complexes. Furthermore, complement can link innate and adaptive immune responses by regulating T cell and B cell responses. The complement system is tightly regulated to avoid uncontrolled activation. Dysregulation of the complement system has been linked to numerous diseases, both rare and common. Uncontrolled or exaggerated activation can lead to life-threatening conditions such as dysregulation of coagulation, fibrinolysis, systemic inflammation and shock, and possible failure of a variety of organs such as the eyes, kidneys, skin, brain, and vascular system. In recent years, the complement system has gained increased interest, especially as a promising candidate for therapeutic intervention. Eculizumab, the first approved complement inhibitor, is highly effective for treating atypical hemolytic uremic syndrome (aHUS) and paroxysmal nocturnal hemoglobinuria (PNH). Many more drug candidates are currently evaluated in ongoing clinical trials.

Complement in Health and Disease

Author : K. Whaley
Publisher : Springer Science & Business Media
ISBN 13 : 9401122148
Total Pages : 385 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Complement in Health and Disease by : K. Whaley

Download or read book Complement in Health and Disease written by K. Whaley and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of Complement in Health and Disease was published in 1986, significant advances have been made. The cDNAs for all of the components and some of the receptors have been cloned and sequenced. The chromosomal localization and the structural organization of a number of these genes have now been determined. These advances are now facilitating research into the structure of the complement proteins, the nature of the complement deficiency syndromes, the regulation of complement gene expression and the role of complement in different diseases. This edition contains contributions from both basic and clinical scientists in a format which we hope will appeal to both immunologists and physicians who wish to know more about this fascinating and important host defence system. The introductory chapter by John Weiler presents a historical background to research on the complement system and describes the biochemical events occurring during activation of the system. In Chapter 2 Alastair Dodds and Tony Day discuss the phylogeny and evolution of the complement system. The techniques of protein chemistry and molecular biology have provided powerful insights into the modular structure of complement proteins and the evolution of the complement system. The structure and organisation of the complement genes is described in Chapter 3 by Ken Reid and Duncan Campbell. This chapter describes the modular structure of the complement proteins and some of the mutations which are responsible for deficiencies of individual components.

Complement Clauses in Portuguese

Author : Ana Lúcia Santos
Publisher : John Benjamins Publishing Company
ISBN 13 : 9027263965
Total Pages : 426 pages
Book Rating : 4.0/5 (272 download)

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Book Synopsis Complement Clauses in Portuguese by : Ana Lúcia Santos

Download or read book Complement Clauses in Portuguese written by Ana Lúcia Santos and published by John Benjamins Publishing Company. This book was released on 2018-08-15 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses core issues on complement clauses, focusing on Portuguese (European, Brazilian and Mozambican varieties). It contributes to the discussion of complementation, providing an overview of how theoretical syntax and acquisition studies may combine to broaden our knowledge about the topic. The articles are organized in two sections, each one followed by a comment paper: the first section, more theoretical in its nature, gathers contributions analyzing major syntactic aspects of complementation in Portuguese, from a synchronic and a diachronic point of view; the second section includes articles on L1 and L2 acquisition of Portuguese complementation. Both sections especially focus on infinitival structures; mood selection and the interpretation of subjects in finite complement clauses are also topics of particular relevance. The volume is meant for researchers and students interested in formal syntax and acquisition in general and Portuguese syntax and acquisition in particular.

Complement-mediated Hemolytic Anemias, An Issue of Hematology/Oncology Clinics of North America,

Author : Robert A. Brodsky
Publisher : Elsevier Health Sciences
ISBN 13 : 0323388914
Total Pages : 233 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Complement-mediated Hemolytic Anemias, An Issue of Hematology/Oncology Clinics of North America, by : Robert A. Brodsky

Download or read book Complement-mediated Hemolytic Anemias, An Issue of Hematology/Oncology Clinics of North America, written by Robert A. Brodsky and published by Elsevier Health Sciences. This book was released on 2015-10-20 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics of North America, guest edted by Dr. Robert Brodsky, is devoted to Complement-mediated Hemolytic Anemias. Articles in this outstanding issue include: Complement: An overview for the clinician; Warm autoimmune hemolytic anemia; Cold Agglutinin Disease; ABO incompatible blood transfusions; Paroxysmal cold hemoglobinuria; Paroxysmal nocturnal hemoglobinuria; Congenital CD59 deficiency; Atypical Hemolytic Uremic Syndrome (HUS); Typical Hemolytic Uremic Syndrome (HUS); Thrombotic thrombocytopenic purpura; and Pharmacologic complement inhibitors.

The Modal System of Earlier Egyptian Complement Clauses

Author : Sami Uljas
Publisher : BRILL
ISBN 13 : 9047420489
Total Pages : 444 pages
Book Rating : 4.0/5 (474 download)

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Book Synopsis The Modal System of Earlier Egyptian Complement Clauses by : Sami Uljas

Download or read book The Modal System of Earlier Egyptian Complement Clauses written by Sami Uljas and published by BRILL. This book was released on 2007-06-30 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work proposes a novel analysis of Complement Clauses in Earlier Egyptian language. Contrary to previous assumptions, the grammatical organisation of these constructions is shown to be based on differentiation between Realis and Irrealis modality. The different types of complement clauses attested in Earlier Egyptian are surveyed utilising recent linguistic research on modality and pragmatics. The discussion is based on numerous examples from the ancient texts and on comparisons with many other languages. Emerging from this investigation is a coherent and principled system for expressing Realis and Irrealis meaning in this most ancient of written languages. This book is of notable value to Egyptologists working with texts and to all those interested in modality, grammar, and cognition.

Complement in Nervous System Disease

Author : Iliana Michailidou
Publisher : Frontiers Media SA
ISBN 13 : 2832532861
Total Pages : 147 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Complement in Nervous System Disease by : Iliana Michailidou

Download or read book Complement in Nervous System Disease written by Iliana Michailidou and published by Frontiers Media SA. This book was released on 2023-09-01 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroinflammation is associated with a wide spectrum of acute and chronic diseases of the central and peripheral nervous system. It causes secondary damage, which is a major determinant for progression and outcome. Activated complement is suspected to be a key player to neuroinflammation. Complement is an important evolutionary ancient system for host anti-microbial aid. It serves the innate immunity and interfaces with the adaptive immunity. Complement recognizes non-cognate or altered-self antigens and devours 'unwanted' cells or cell compartments. Activation of complement leads to opsonisation of a target, inflammation by the release of anaphylatoxins, and damage of the target by the assembled membrane attack complex. Because complement can harm self-tissue, activation is tightly controlled by regulators. However, complement activation might be excessive and uncontrolled at sites of damage contributing to neuroinflammation leading to neurodegeneration.

Mood Choice in Complement Clauses

Author : Toth
Publisher : Peter Lang
ISBN 13 : 9783631572573
Total Pages : 168 pages
Book Rating : 4.5/5 (725 download)

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Book Synopsis Mood Choice in Complement Clauses by : Toth

Download or read book Mood Choice in Complement Clauses written by Toth and published by Peter Lang. This book was released on 2008 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume investigates various approaches to mood distribution and mood variation in lexically selected complement clauses with special reference to Hungarian data. Its primary aim is to show that semantic factors play a crucial role in mood choice. The analysis focuses on the indicative/non-indicative opposition, the latter category includes the subjunctive, the imperative and the conditional. Critical discussion, revision and elaboration of previous semantic approaches pertaining to mood choice are presented, with particular emphasis on the applicability of the various analyses to mood phenomena in Hungarian. The author proposes two novel hypotheses about mood choice in Hungarian complement clauses.

Cytolytic Lymphocytes and Complement Effectors of the Immune System

Author : Eckhard R. Podack
Publisher : CRC Press
ISBN 13 : 1351088203
Total Pages : 272 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Cytolytic Lymphocytes and Complement Effectors of the Immune System by : Eckhard R. Podack

Download or read book Cytolytic Lymphocytes and Complement Effectors of the Immune System written by Eckhard R. Podack and published by CRC Press. This book was released on 2018-01-18 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes, Cytolytic Lymphocytes and Complement: Effectors of the Immune System, originate from the realization that pathways of recognition and killings of foreign targets follow similar routes in the humoral and cellular part of the immune system. In particular, the homology of immunoglobins with the T-cell-MHC-antigen receptor at the beginning of the recognition sequence and the homology of complement component C9 with lymphocyte perforin 1 (P1) as pore formers at the end of the effector sequence are striking examples.