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Author : John B. Zabriskie
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)
Download or read book Clinical Immunology of the Heart written by John B. Zabriskie and published by John Wiley & Sons. This book was released on 1981 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Susanne Sattler
Publisher : Springer
ISBN 13 : 3319576135
Total Pages : 283 pages
Book Rating : 4.3/5 (195 download)
Download or read book The Immunology of Cardiovascular Homeostasis and Pathology written by Susanne Sattler and published by Springer. This book was released on 2017-06-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.
Author : Heinz-Peter Schultheiss
Publisher : Springer Science & Business Media
ISBN 13 : 3642604633
Total Pages : 496 pages
Book Rating : 4.6/5 (426 download)
Download or read book The Role of Immune Mechanisms in Cardiovascular Disease written by Heinz-Peter Schultheiss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: An involvement of the immune system is suspected in various cardiovascular diseases. Recent advances in the fields of molecular biology, genetics, cell biology, and immunology have made it possible to identify several pathomechanisms. However, still more questions arise with regard to the pathophysiology, diagnosis, and treatment of immunologically mediated cardiovascular diseases. In this book, leading scientists and clinicians from different areas of cardiology present the state-of-the-art knowledge on the involve ment of the immune system in myocardial and vascular diseases. In the field of myocarditis, both the virological and the immunological findings are presented, and the interactions between the virus and the immune system are discussed. Since the cellular immune system and its mediators play an important role in the inflammation by bacteria that cause endocarditis and septic shock, studies investigating the underlying pathomechanisms are de scribed. Another major topic in this volume is the involvement of the immune system in arteriosclerosis and coronary heart disease, which represents an important problem in clinical cardiology. The final chapter addresses the question of therapeutic options, presenting new approaches for a specific and effective therapy based on the current knowledge of immunologically mediated cardiovascular diseases.
Author : Maurice H. Lessof
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunology of Cardiovascular Disease written by Maurice H. Lessof and published by . This book was released on 1981 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mohamed Boutjdir
Publisher : Frontiers Media SA
ISBN 13 : 2889633977
Total Pages : 263 pages
Book Rating : 4.8/5 (896 download)
Download or read book Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease written by Mohamed Boutjdir and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Matthijs Blankesteijn
Publisher : Academic Press
ISBN 13 : 0128004851
Total Pages : 221 pages
Book Rating : 4.1/5 (28 download)
Download or read book Inflammation in Heart Failure written by Matthijs Blankesteijn and published by Academic Press. This book was released on 2014-12-05 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases
Author : Ronald Ross Watson
Publisher : John Wiley & Sons
ISBN 13 : 9780470766514
Total Pages : 328 pages
Book Rating : 4.7/5 (665 download)
Download or read book Immune Dysfunction and Immunotherapy in Heart Disease written by Ronald Ross Watson and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current heart failure therapeutics affects symptoms without appreciably reducing the mortality rate of 50% in five years -- suggesting a failure in treating the underlying mechanism. This book proposes a new mechanism for heart failure; immune mediated cardiac remodelling for cardiac dysfunction. The outstanding editor team of two internationally recognized immunologists -- Ronald Watson, who has studied heart disease in immune dysfunction for a decade and has a patent for an immunotherapy of heart disease by immune regulation, and Douglas Larson, whose experience in cardiac transplantation immunology has provided the foundation for research into novel therapeutics for heart failure and hypertension – makes Immune Dysfunction and Immunotherapy in Heart Disease the definitive reference to the state of the science in this area. The four parts of the book address: Immune Dysfunction Leading to Heart Disease: Induction by Physiological Changes Immune Dysfunction Promoting CVD: Induction by Transplantation Drugs Immune Dysfunction Leading to Heart Dysfunction: Induction or Prevention by Cardiotherapeutic Drugs Immune Dysfunction Leading to Heart Disease: Induction by Pathogens Both researchers and practitioners will find this authoritative volume an excellent source of information on novel immune targeted therapeutics.
Author : Andrea Dorea
Publisher : Elsevier
ISBN 13 : 0080507964
Total Pages : 276 pages
Book Rating : 4.0/5 (85 download)
Download or read book The Heart in Systemic Autoimmune Diseases written by Andrea Dorea and published by Elsevier. This book was released on 2004-01-20 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined. This book yields an impressive body of well ordered information, highlighting key references and summarising the experience of a selected panel of distinguished physician-scientists actively involved in the field of cardiovascular disease and systemic autoimmunity.
Author : H.P. Schultheiß
Publisher : Springer Science & Business Media
ISBN 13 : 3642736106
Total Pages : 503 pages
Book Rating : 4.6/5 (427 download)
Download or read book New Concepts in Viral Heart Disease written by H.P. Schultheiß and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent rapid advances in our knowledge of immunological and virological mechanisms involved in the pathogenesis of viral heart disease makes it difficult for everybody working in this field to keep up with the latest developments. How ever, much of what we know is still circumstantial and only vaguely substained. Interdisciplinary understanding and cooperation thus seems necessary to get a better insight into the mechanisms by which viruses may initiate immunological organ-specific tissue injury and disease! This volume evolved out of an international symposium by the same title held on May 25. -28. , 1988 in Tegernsee, near Munich, of which a wide spectrum ofim munological, virological, diagnostical and clinical problems was covered. Both review articles and new experimental and clinical data are included in this volume to give the reader an up-to-date information about current concepts and future aspects. Chapter I serves as an excellent introduction to the epidemiology and natural history of dilated cardiomyopathy / viral heart disease. Although a definite viral etiology in myocarditis and dilated cardiomyopathy is often difficult to establish, epidemiological and serological data incriminate a viral etiology underlying many cases of "dilated cardiomyopathy". Chapters II and III describe the current think ing on virological and immunological mechanisms involved in the pathogenesis of viral heart disease. Among others virus topism, virus persistance, possible mecha nisms and genetic basis of post-infection autoimmunity, and the virus-interaction with the immune system are discussed.
Author : L. Maximilian Buja
Publisher : Academic Press
ISBN 13 : 0128004592
Total Pages : 833 pages
Book Rating : 4.1/5 (28 download)
Download or read book Cardiovascular Pathology written by L. Maximilian Buja and published by Academic Press. This book was released on 2015-11-11 with total page 833 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. Customers buy the Print + Electronic product together! Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation
Author : Udi Nussinovitch
Publisher : Academic Press
ISBN 13 : 0128032685
Total Pages : 766 pages
Book Rating : 4.1/5 (28 download)
Download or read book The Heart in Rheumatic, Autoimmune and Inflammatory Diseases written by Udi Nussinovitch and published by Academic Press. This book was released on 2017-02-10 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
Author : Leonard S. Lilly
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975120604
Total Pages : 917 pages
Book Rating : 4.9/5 (751 download)
Download or read book Pathophysiology of Heart Disease written by Leonard S. Lilly and published by Lippincott Williams & Wilkins. This book was released on 2020-05-26 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enthusiastically acclaimed by medical students and faculty worldwide, this text is specifically designed to prepare students for their first encounters with patients with cardiovascular disease. Thoroughly revised by internationally recognized Harvard Medical School faculty and a team of select cardiology fellows and internal medicine residents, this seventh edition equips students with a clear, complete, and clinically relevant understanding of cardiovascular pathophysiology, setting a strong foundation for patient diagnosis and management.
Author : C.J. Spry
Publisher : Springer
ISBN 13 : 0852009739
Total Pages : 288 pages
Book Rating : 4.8/5 (52 download)
Download or read book Immunology and Molecular Biology of Cardiovascular Diseases written by C.J. Spry and published by Springer. This book was released on 1987-11-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : H. P. Schultheiss
Publisher :
ISBN 13 : 9783642736117
Total Pages : 520 pages
Book Rating : 4.7/5 (361 download)
Download or read book New Concepts in Viral Heart Disease written by H. P. Schultheiss and published by . This book was released on 1988-11-22 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Elena Aikawa
Publisher : BoD – Books on Demand
ISBN 13 : 9535111507
Total Pages : 544 pages
Book Rating : 4.5/5 (351 download)
Download or read book Calcific Aortic Valve Disease written by Elena Aikawa and published by BoD – Books on Demand. This book was released on 2013-06-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
Author : Nima Rezaei
Publisher : Academic Press
ISBN 13 : 0128180072
Total Pages : 700 pages
Book Rating : 4.1/5 (281 download)
Download or read book Clinical Immunology written by Nima Rezaei and published by Academic Press. This book was released on 2022-08-16 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology. Provides essentials, updates clinical knowledge regarding immune system diseases, and cover different aspects of clinical immunology, from immunopathogenesis and etiology to diagnosis and treatment Introduces the most advanced approaches and laboratory tests as well as their interpretation in the diagnosis of immune system disorders Focuses on the practical use of clinical immunology, from bedside to bench and vice versa
Author : Bibekanand Mallick
Publisher : Academic Press
ISBN 13 : 0128156708
Total Pages : 387 pages
Book Rating : 4.1/5 (281 download)
Download or read book AGO-Driven Non-Coding RNAs written by Bibekanand Mallick and published by Academic Press. This book was released on 2019-01-20 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases. Provides a unified cutting-edge resource for both miRNAs and piRNAs, two promising AGO-clade small ncRNAs, their functions and potential applications Showcase high-throughput technologies and other approaches for discovery of these small ncRNAs and their targets Unveils the diverse molecular mechanisms by which miRNAs and piRNAs regulate gene expression in animal cells Showcase recent discoveries on involvement of Argonaute and Piwi proteins in different biological processes and diseases as well as their possible use in diagnosis Report breakthroughs in the use of small ncRNAs for diagnosis and personalized therapy
