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The Immunology Of Cardiovascular Homeostasis And Pathology
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Book Synopsis The Immunology of Cardiovascular Homeostasis and Pathology by : Susanne Sattler
Download or read book The Immunology of Cardiovascular Homeostasis and Pathology written by Susanne Sattler and published by Springer. This book was released on 2017-06-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.
Book Synopsis Immune Cells, Inflammation, and Cardiovascular Diseases by : Shyam S. Bansal
Download or read book Immune Cells, Inflammation, and Cardiovascular Diseases written by Shyam S. Bansal and published by CRC Press. This book was released on 2022-04-19 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation, once considered a physiological response to foreign pathogens, is now recognized as a crucial pathological player in the initiation and progression of several chronic diseases, including diabetes, obesity, cancer, Alzheimer’s disease, Parkinson’s disease, and many others. Considering that cardiovascular diseases are a leading cause of death in the United States and worldwide, the identification of critical inflammatory processes is of utmost importance to devising new immune-based therapeutics that can be added to existing regimens. This book provides detailed information on aspects of inflammation and the manner in which immune activation pathways affect the progression of cardiovascular diseases and the repair/regeneration mechanisms of underlying diseased tissues. Key Features Outlines the role that inflammation plays in cardiovascular diseases Describes a paradox – neutralization of cytokines that contribute to cardiovascular disease does not show benefit Summarizes research on a variety of processes and mechanisms contributing to cardiovascular pathology Contributions from an international team of leading cardiologists and cardiovascular immunologists Related Titles Roy, S., et al., eds. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions (ISBN 978-1-138-19955-2) Kong, A-N. T., ed. Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention (ISBN 978-1-138-19984-2) Dick, A., et al. Practical Manual of Intraocular Inflammation (ISBN 978-0-367-38720-4)
Book Synopsis Probiotics in The Prevention and Management of Human Diseases by : Mitesh Kumar Dwivedi
Download or read book Probiotics in The Prevention and Management of Human Diseases written by Mitesh Kumar Dwivedi and published by Academic Press. This book was released on 2021-12-02 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease. Contains information on the use of probiotics in significant human diseases, including antibiotic resistant microbial infections Presents novel applications of probiotics, including their use in vaccine adjuvants and concept of pharmabiotics Includes case studies and human clinical trials for probiotics in diverse disease conditions and explores the role of probiotics in mitigation of the symptoms of disease
Author :Prof. C. Kalyan Chakravarthi, Dr. K. Sravani Pragna , Dr. E. Muralinath and Dr. M. Guru Prasad Publisher :Laxmi Book Publication ISBN 13 :130436819X Total Pages :131 pages Book Rating :4.3/5 (43 download)
Book Synopsis CLINICAL REVIEW ARTICLES IN PHYSIO PHARMACOLOGY VOLUME IV by : Prof. C. Kalyan Chakravarthi, Dr. K. Sravani Pragna , Dr. E. Muralinath and Dr. M. Guru Prasad
Download or read book CLINICAL REVIEW ARTICLES IN PHYSIO PHARMACOLOGY VOLUME IV written by Prof. C. Kalyan Chakravarthi, Dr. K. Sravani Pragna , Dr. E. Muralinath and Dr. M. Guru Prasad and published by Laxmi Book Publication. This book was released on 2024-05-11 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute and chronic hypoxia results in unconsciousness. Brain death happens immediately without proper treatment. Hypoxia activates Juxta glomerular (JG) apparatus of kidneys and enhances the secretion of erythroietin which in turn activates the red bone marrow to enhance the RBC count. Hypoxia enhances the rate and force of contraction of heart, cardiac output (COP) as well as blood pressure. Hypoxia enhances the respiratory because of the stimulation of chemoreceptor reflex.
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Pathology by : William B. Coleman
Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase
Book Synopsis Coagulation/Endothelial Dysfunction ,An Issue of Critical Care Clinics by : Hernando Gomez
Download or read book Coagulation/Endothelial Dysfunction ,An Issue of Critical Care Clinics written by Hernando Gomez and published by Elsevier Health Sciences. This book was released on 2020-03-19 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Critical Care Clinics, guest edited by Drs. Hernando Gomez Danies and Joseph Carcillo, focuses on Coagulation/Endothelial Dysfunction. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Cell-cell communication breakdown and endothelial dysfunction; Role of the Tie2/Angiopoetin pathway in endothelial dysfunction; The Glycocalyx; Platelet activation and endothelial dysfunction; Role of antithrombin III and tissue factor pathway; Red blood cell dysfunction; Microvascular hemodynamics, autoregulation and mechanotransduction control of blood flow distribution; Nitric oxide and endothelial dysfunction; Microvascular dysfunction; Hemolytic Uremic Syndrome and atypical HUS; Thrombotic thrombocytopenic purpura, Heparin induced thrombocytopenia and Disseminated intravascular coagulation in the critically ill; Thrombocytopenia associated multiple organ failure (TAMOF); Meningococcemia; Immune consequences of endothelial dysfunction during sepsis; Therapeutic targets in thrombotic microangiopathies with a focus on endothelial disorders; and Coagulation disorders in HLH/Macrophage activation syndrome.
Book Synopsis Pulmonary Hypertension in the Modern Era: Science and Clinical Practice by : Elena Goncharova
Download or read book Pulmonary Hypertension in the Modern Era: Science and Clinical Practice written by Elena Goncharova and published by Frontiers Media SA. This book was released on 2021-12-31 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fundamentals of Toxicologic Pathology by : Wanda M. Haschek
Download or read book Fundamentals of Toxicologic Pathology written by Wanda M. Haschek and published by Academic Press. This book was released on 2009-11-23 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. 25% brand new information, fully revised throughout New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology New color photomicrographs detailing specific toxicant-induced diseases in animals Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
Book Synopsis How Tobacco Smoke Causes Disease by :
Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Neuroinflammation, Resolution, and Neuroprotection in the Brain by : Akhlaq A. Farooqui
Download or read book Neuroinflammation, Resolution, and Neuroprotection in the Brain written by Akhlaq A. Farooqui and published by Academic Press. This book was released on 2021-09-15 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroinflammation, Resolution, and Neuroprotection in the Brain discusses the molecular aspects of neuroinflammation in neurological disorders. The book examines the effect of diet and exercise on neuroinflammatory diseases. Chapters focus on bioactive lipids, cytokines and chemokines, as well as the involvement of neuroinflammation, resolution and neuroprotection in neurotraumatic diseases, neurodegenerative diseases and neuropsychiatric diseases. The comprehensive information in this monograph will help readers understand molecular cross-talk among mediators of phospholipid, sphingolipid and cholesterol metabolism. The book's goal is to jumpstart more studies on molecular mechanisms and the therapeutic aspects of neurological disorders in human subjects. Discusses the molecular aspects of neuroinflammation, resolution and neuroprotection Examines the role of diet and exercise on neuroinflammatory diseases Provides cutting-edge research on signal transduction processes Explores the treatment of neurological disorders caused by neuroinflammation
Book Synopsis Cell Communication in Vascular Biology by : Xavier F. Figueroa
Download or read book Cell Communication in Vascular Biology written by Xavier F. Figueroa and published by Frontiers Media SA. This book was released on 2021-04-07 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Circuits of Resident Immunity Regulating Tissue Adaptation and Organ Homeostasis by : Christoph S. N. Klose
Download or read book Circuits of Resident Immunity Regulating Tissue Adaptation and Organ Homeostasis written by Christoph S. N. Klose and published by Frontiers Media SA. This book was released on 2022-05-03 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Calcific Aortic Valve Disease by : Elena Aikawa
Download or read book Calcific Aortic Valve Disease written by Elena Aikawa and published by BoD – Books on Demand. This book was released on 2013-06-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
Book Synopsis Progress in Catheter Ablation by : Liong Bing Liem
Download or read book Progress in Catheter Ablation written by Liong Bing Liem and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catheter ablation is widely accepted as an effective and safe form of therapy for cardiac arrhythmia. In many instances this curative procedure is considered as the first line of therapy if not the ultimate treatment of choice. With the use of radiofrequency (RF) modality; which has revolutionized the technology from a barotraumatic, potentially injurious procedure using high voltage, direct-current (DC) shock to a safe and relatively painless one; catheter ablation procedure now carries a very low risk and is extremely effective for certain types of arrhythmia. Its efficacy rate in curing supraventricular tachycardia involving an accessory pathway or dual atrioventricular nodal pathways has been near perfect and its application for certain types of atrial and ventricular arrhythmia have also been very satisfactory. However, conventional RF ablation has several well known limitations, most notably is its ability to only produce relatively small, point lesions; rendering it effective only for an arrhythmia with a small and/or a superficial target. It was soon recognized that the technology would not likely to have significant utility in arrhythmia with a more widespread target such as atrial fibrillation or those which involve scarred and deep myocardial tissue such as ventricular tachycardia. Indeed, the application of conventional RF technology in these complex but common arrhythmia has yielded unsatisfactory results.
Book Synopsis Current Challenges in Complement Diagnostics by : Erik J.M. Toonen
Download or read book Current Challenges in Complement Diagnostics written by Erik J.M. Toonen and published by Frontiers Media SA. This book was released on 2023-12-14 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complement system is an important innate immune surveillance network that has a key role in protecting our bodies against pathogens and other threats. It is a highly complex system consisting of approximately 50 soluble and cell surface-bound proteins that interact to eliminate danger signals. These signals include factors such as invading microorganisms, necrotic cells, and immune complexes. Furthermore, complement can link innate and adaptive immune responses by regulating T cell and B cell responses. The complement system is tightly regulated to avoid uncontrolled activation. Dysregulation of the complement system has been linked to numerous diseases, both rare and common. Uncontrolled or exaggerated activation can lead to life-threatening conditions such as dysregulation of coagulation, fibrinolysis, systemic inflammation and shock, and possible failure of a variety of organs such as the eyes, kidneys, skin, brain, and vascular system. In recent years, the complement system has gained increased interest, especially as a promising candidate for therapeutic intervention. Eculizumab, the first approved complement inhibitor, is highly effective for treating atypical hemolytic uremic syndrome (aHUS) and paroxysmal nocturnal hemoglobinuria (PNH). Many more drug candidates are currently evaluated in ongoing clinical trials.
Book Synopsis Cellular and Molecular Pathobiology of Cardiovascular Disease by : Monte Willis
Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology
