The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 0128032685
Total Pages : 766 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Heart in Rheumatic, Autoimmune and Inflammatory Diseases by : Udi Nussinovitch

Download or read book The Heart in Rheumatic, Autoimmune and Inflammatory Diseases written by Udi Nussinovitch and published by Academic Press. This book was released on 2017-02-10 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

Acute Rheumatic Fever and Rheumatic Heart Disease

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323754600
Total Pages : 364 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Acute Rheumatic Fever and Rheumatic Heart Disease by : Dr. Scott Dougherty

Download or read book Acute Rheumatic Fever and Rheumatic Heart Disease written by Dr. Scott Dougherty and published by Elsevier Health Sciences. This book was released on 2020-02-22 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. International editors and chapter authors ensure a truly global perspective. Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. Consolidates today’s available information and guidance into a single, convenient resource.

The Heart in Systemic Autoimmune Diseases

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Author :
Publisher : Elsevier
ISBN 13 : 0080507964
Total Pages : 276 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Heart in Systemic Autoimmune Diseases by : Andrea Dorea

Download or read book The Heart in Systemic Autoimmune Diseases written by Andrea Dorea and published by Elsevier. This book was released on 2004-01-20 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined. This book yields an impressive body of well ordered information, highlighting key references and summarising the experience of a selected panel of distinguished physician-scientists actively involved in the field of cardiovascular disease and systemic autoimmunity.

Coronary Microvascular Dysfunction

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 8847053676
Total Pages : 257 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Coronary Microvascular Dysfunction by : Filippo Crea

Download or read book Coronary Microvascular Dysfunction written by Filippo Crea and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Skills in Rheumatology

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Author :
Publisher : Springer Nature
ISBN 13 : 9811583234
Total Pages : 562 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Skills in Rheumatology by : Hani Almoallim

Download or read book Skills in Rheumatology written by Hani Almoallim and published by Springer Nature. This book was released on 2021-01-05 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.

Autoimmune Rheumatic Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : 294 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Autoimmune Rheumatic Disease by : John Morrow

Download or read book Autoimmune Rheumatic Disease written by John Morrow and published by . This book was released on 1999 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Autoimmune Rheumatic Disease (second edition) is a new fully revised edition of the award winning title. It fills the gap in the literature in that no other book bridges the divide between the clinical characterisation and treatment of autoimmune rheumatic diseases on the one hand and an understanding of laboratory-based research and disease pathogenesis on the other. This second edition is especially important because it describes and explains the advances in molecular biological techniques that have brought about major changes in understanding and also covers the new therapies which have been developed for many autoimmune rheumatic diseases.

AGO-Driven Non-Coding RNAs

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Author :
Publisher : Academic Press
ISBN 13 : 0128156708
Total Pages : 387 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis AGO-Driven Non-Coding RNAs by : Bibekanand Mallick

Download or read book AGO-Driven Non-Coding RNAs written by Bibekanand Mallick and published by Academic Press. This book was released on 2019-01-20 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases. Provides a unified cutting-edge resource for both miRNAs and piRNAs, two promising AGO-clade small ncRNAs, their functions and potential applications Showcase high-throughput technologies and other approaches for discovery of these small ncRNAs and their targets Unveils the diverse molecular mechanisms by which miRNAs and piRNAs regulate gene expression in animal cells Showcase recent discoveries on involvement of Argonaute and Piwi proteins in different biological processes and diseases as well as their possible use in diagnosis Report breakthroughs in the use of small ncRNAs for diagnosis and personalized therapy

Into the Heart of Systemic Autoimmune Diseases

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 283254682X
Total Pages : 119 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Into the Heart of Systemic Autoimmune Diseases by : Franco Franceschini

Download or read book Into the Heart of Systemic Autoimmune Diseases written by Franco Franceschini and published by Frontiers Media SA. This book was released on 2024-03-27 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic autoimmune diseases are a heterogeneous group of disorders characterized by humoral and cell-mediated immune responses against various self-constituents. In specific cases, the heart and cardiovascular (CV) system are the primary organs targeted by the disease. On the other hand, several systemic autoimmune conditions are linked to enhanced atherosclerosis, with a consequently high CV morbidity and mortality rates. Persistent low-grade inflammation in the vascular wall is described to be important in the physiopathology of CV events. At first, inflammation is linked to endothelial dysfunction supporting the proliferation of vascular smooth muscle cells with subsequent vascular remodeling. Furthermore, the infiltration of innate and adaptive immune cells promotes a milieu of molecules that contributes to the perpetuation of inflammation itself. Although CV risk assessment should be part of routine care in patients with autoimmune diseases, no disease-specific models are currently available for this purpose. The main pillars of CV risk reduction are pharmacological and nonpharmacological management of cardiovascular CV risk factors, as well as tight control of disease activity.

The Autoimmune Brain

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Author :
Publisher : Rowman & Littlefield
ISBN 13 : 1538117711
Total Pages : 289 pages
Book Rating : 4.5/5 (381 download)

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Book Synopsis The Autoimmune Brain by : David S. Younger

Download or read book The Autoimmune Brain written by David S. Younger and published by Rowman & Littlefield. This book was released on 2019-11-10 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are millions of people who experience issues related to brain health—depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain—yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or anti-anxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age—from children to teens or seniors—people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. The Autoimmune Brain connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease; Anxiety; Arthritis; Autism; Autonomic disturbances; Bacterial and viral infections; Bipolar Disorder; Cancer; Celiac disease and gluten intolerances; Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease); Chronic Pain; Dementia; Depression; Endocrine Disorders; Immune modulatory therapy using IVIg; Lyme disease and co-infections; Mast cell activation syndrome; Medical cannabis; Obsessive Compulsive Disorder; Orthostatic hypotension; Peripheral Neuropathy; Porphyria; Post-Traumatic Stress Disorder; and Postural orthostatic tachycardia.

Innovative Medicine

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Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Current Rheumatology Diagnosis & Treatment

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Author :
Publisher : McGraw-Hill/Appleton & Lange
ISBN 13 :
Total Pages : 532 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Rheumatology Diagnosis & Treatment by : John B. Imboden

Download or read book Current Rheumatology Diagnosis & Treatment written by John B. Imboden and published by McGraw-Hill/Appleton & Lange. This book was released on 2004 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal quick reference for primary care providers, specialists, and trainees, this accessible resource offers up-to-date assessment and management solutions for the entire range of rheumatologic diseases.

Cardiovascular complications of chronic rheumatic diseases, An Issue of Rheumatic Disease Clinics of North America, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323849296
Total Pages : 209 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Cardiovascular complications of chronic rheumatic diseases, An Issue of Rheumatic Disease Clinics of North America, E-Book by : M. Elaine Husni︎

Download or read book Cardiovascular complications of chronic rheumatic diseases, An Issue of Rheumatic Disease Clinics of North America, E-Book written by M. Elaine Husni︎ and published by Elsevier Health Sciences. This book was released on 2022-11-24 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Rheumatic Disease Clinics, guest editors Drs. M. Elaine Husni? and George A. Karpouzas bring their considerable expertise to the topic of Cardiovascular Complications of Chronic Rheumatic Diseases. Top experts in the field cover key topics such as primary and secondary atherosclerotic cardiovascular (ASCVD) risk prevention in the rheumatic disease, pro-thrombotic and pro-atherogenic anti-phospholipid antibodies, recommendations for the use of NSAIDs and CVD risk, and more. Contains 9 relevant, practice-oriented topics including atherosclerotic cardiovascular risk stratification in the rheumatic diseases; subclinical atherosclerosis evaluation across various vascular territories; lessons from heart and large vessel biopsies in patients with and without autoimmune rheumatic disease; the role of lipoprotein levels and function in atherosclerosis associated with autoimmune rheumatic diseases; and more. Provides in-depth clinical reviews on cardiovascular complications of chronic rheumatic diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The Autoimmune Epidemic

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Author :
Publisher : Simon and Schuster
ISBN 13 : 0743277767
Total Pages : 352 pages
Book Rating : 4.7/5 (432 download)

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Book Synopsis The Autoimmune Epidemic by : Donna Jackson Nakazawa

Download or read book The Autoimmune Epidemic written by Donna Jackson Nakazawa and published by Simon and Schuster. This book was released on 2009-02-10 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do our bodies rebel against themselves? Why are autoimmunine disorders on the rise? What role do everyday environmental toxins play in triggering onset of these diseases? The author answers these questions with personal stories and sound scientific research and offers ways to combat the problem.

Primer on the Rheumatic Diseases

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Author :
Publisher :
ISBN 13 :
Total Pages : 534 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Primer on the Rheumatic Diseases by : John H. Klippel

Download or read book Primer on the Rheumatic Diseases written by John H. Klippel and published by . This book was released on 1997 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook for health-care professionsl and students covering the rheumatic diseases, including arthritis, lupus, osteoporosis, fibromyalgia and more.

The Autoimmune Diseases

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Author :
Publisher :
ISBN 13 :
Total Pages : 928 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Autoimmune Diseases by : Noel R. Rose

Download or read book The Autoimmune Diseases written by Noel R. Rose and published by . This book was released on 1998 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.

Janeway's Immunobiology

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Author :
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Oxford Handbook of Rheumatology

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199587183
Total Pages : 674 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Oxford Handbook of Rheumatology by : Alan Hakim

Download or read book Oxford Handbook of Rheumatology written by Alan Hakim and published by Oxford University Press. This book was released on 2011-09-22 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a handbook of clinical rheumatology that provides practical guidelines to management and diagnosis. It is essential for all specialist registrars and SHO's but will also be of great relevance to general practitioners.