Chasing Pain The Search For A Neurobiological Mechanism

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Chasing Pain: The Search for a Neurobiological Mechanism

Author : Kenneth L. Casey
Publisher : Oxford University Press
ISBN 13 : 0190920084
Total Pages : 208 pages
Book Rating : 4.1/5 (99 download)

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Book Synopsis Chasing Pain: The Search for a Neurobiological Mechanism by : Kenneth L. Casey

Download or read book Chasing Pain: The Search for a Neurobiological Mechanism written by Kenneth L. Casey and published by Oxford University Press. This book was released on 2019-02-22 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conceptual models of how pain is created influence medical practice, neuroscientific research, and philosophical ideas about pain and other neurological functions. Given the broad scope of pain experiences, realistic models of pain neurobiology must consider the correlation between pain and tissue damage and how it is strongly affected by neurological disease, emotionally compelling circumstances, and by complex cognitive processes. Recent discoveries have made it clear that both sensory and affective systems are strongly modulated by activity in other sensory pathways and by affective and cognitive processes originating in the brain. As a result, pain should then be conceived as emerging from the conjoint activity of both sensory and affective neural systems, each becoming a target for pain treatment. Historically, pain has been conceived as emerging either from an undefined pattern of neural activity or from anatomically and physiologically unique structures in the nervous system. Observations made during the early and mid- 20th century showed that pain and pain-like behaviors normally require not only sensory detectors of noxious events (called nociceptors) but also brain affective (hedonic) mechanisms that generate emotional experience and expression. In Chasing Pain, pain specialists and neuroscientists will find a thoughtful discussion of the neuroscientific and clinical evidence that has led to contemporary concepts of pain neurobiology and how pain might emerge from neuronal activity. Written in a concise and annotated format, Doctor Kenneth Casey reveals that while contemporary research has greatly enriched our model of pain neurobiology, several important and therapeutically challenging clinical conditions remain poorly understood.

The Right to Pain Relief and Other Deep Roots of the Opioid Epidemic

Author : Mark Sullivan
Publisher : Oxford University Press
ISBN 13 : 0197615724
Total Pages : 305 pages
Book Rating : 4.1/5 (976 download)

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Book Synopsis The Right to Pain Relief and Other Deep Roots of the Opioid Epidemic by : Mark Sullivan

Download or read book The Right to Pain Relief and Other Deep Roots of the Opioid Epidemic written by Mark Sullivan and published by Oxford University Press. This book was released on 2023-01-24 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pain has always been a problem for Western Society, but not the same kind of problem. Until about 1500, pain was primarily understood as a religious problem. Pain and suffering challenged the truth of religious belief and the legitimacy of the Church: How could a just, merciful, and all-powerful God allow so much pain and suffering in the world? As our society became more secular over the next 300 years, pain came to be understood primarily as a social problem. This modernizing society aimed to create the best environment for human flourishing: How might human society be designed and regulated to reduce the pain and suffering of everyone to the minimum possible? At least since 1900, we have separated pain as a medical problem from the remainder of human suffering. We have aimed to reduce this problem to a minimum through medical treatment. This quest has led us to our opioid epidemic. To fully comprehend the limitations of this medical interpretation, we must appreciate how the medical explanation of pain grew out of earlier religious and social interpretations of pain"--

The Brain as a Tool

Author : Ray Guillery
Publisher : Oxford University Press
ISBN 13 : 0198806736
Total Pages : 289 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis The Brain as a Tool by : Ray Guillery

Download or read book The Brain as a Tool written by Ray Guillery and published by Oxford University Press. This book was released on 2017 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two distinct views about the functions of our brains and their origins. The standard view, taught in most neuroscience texts, has incoming messages about the world sent to the cerebral cortex, with the cortex then producing an appropriate motor output. The interactive view, largely expressed by philosophers and psychologists, stresses the continuous sensorimotor interactions of the brain with the world. The Brain as a Tool focuses on thalamo-cortical interactions on the basis of the interactive view, exploring the phylogenetically new transthalamic corticocortical pathways of mammals that link a hierarchy of cortical areas to each other and back to the phylogenetically older motor centres for control of action. The book demonstrates how messages in these pathways produce an anticipation of our own actions and perceptions. In relating neural events to conscious processing and our sense of self , Guillery summarizes important evidence which links neuroscience with psychology and philosophy. This book is essential reading for neuroscientists, cognitive psychologists and philosophers. Supplemented with a helpful glossary of neural terms and numerous illustrations of the brain, it is also an important resource for graduate and postdoctoral students interested in the neural bases of a sense of self and of cognitive functions.

Introduction to Neuroimaging Analysis

Author : Mark Jenkinson
Publisher : Oxford University Press
ISBN 13 : 0198816308
Total Pages : 277 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Introduction to Neuroimaging Analysis by : Mark Jenkinson

Download or read book Introduction to Neuroimaging Analysis written by Mark Jenkinson and published by Oxford University Press. This book was released on 2018 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This accessible primer gives an introduction to the wide array of MRI-based neuroimaging methods that are used in research. It provides an overview of the fundamentals of what different MRI modalities measure, what artifacts commonly occur, the essentials of the analysis, and common 'pipelines'

Neuroeconomics

Author : Paul W. Glimcher
Publisher : Academic Press
ISBN 13 : 0123914698
Total Pages : 560 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Neuroeconomics by : Paul W. Glimcher

Download or read book Neuroeconomics written by Paul W. Glimcher and published by Academic Press. This book was released on 2013-08-13 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since it first published, Neuroeconomics: Decision Making and the Brain has become the standard reference and textbook in the burgeoning field of neuroeconomics. The second edition, a nearly complete revision of this landmark book, will set a new standard. This new edition features five sections designed to serve as both classroom-friendly introductions to each of the major subareas in neuroeconomics, and as advanced synopses of all that has been accomplished in the last two decades in this rapidly expanding academic discipline. The first of these sections provides useful introductions to the disciplines of microeconomics, the psychology of judgment and decision, computational neuroscience, and anthropology for scholars and students seeking interdisciplinary breadth. The second section provides an overview of how human and animal preferences are represented in the mammalian nervous systems. Chapters on risk, time preferences, social preferences, emotion, pharmacology, and common neural currencies—each written by leading experts—lay out the foundations of neuroeconomic thought. The third section contains both overview and in-depth chapters on the fundamentals of reinforcement learning, value learning, and value representation. The fourth section, “The Neural Mechanisms for Choice, integrates what is known about the decision-making architecture into state-of-the-art models of how we make choices. The final section embeds these mechanisms in a larger social context, showing how these mechanisms function during social decision-making in both humans and animals. The book provides a historically rich exposition in each of its chapters and emphasizes both the accomplishments and the controversies in the field. A clear explanatory style and a single expository voice characterize all chapters, making core issues in economics, psychology, and neuroscience accessible to scholars from all disciplines. The volume is essential reading for anyone interested in neuroeconomics in particular or decision making in general. Editors and contributing authors are among the acknowledged experts and founders in the field, making this the authoritative reference for neuroeconomics Suitable as an advanced undergraduate or graduate textbook as well as a thorough reference for active researchers Introductory chapters on economics, psychology, neuroscience, and anthropology provide students and scholars from any discipline with the keys to understanding this interdisciplinary field Detailed chapters on subjects that include reinforcement learning, risk, inter-temporal choice, drift-diffusion models, game theory, and prospect theory make this an invaluable reference Published in association with the Society for Neuroeconomics—www.neuroeconomics.org Full-color presentation throughout with numerous carefully selected illustrations to highlight key concepts

Oxford Textbook of Anaesthesia for the Elderly Patient

Author : Christopher Dodds
Publisher : OUP Oxford
ISBN 13 : 0191081175
Total Pages : 336 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Anaesthesia for the Elderly Patient by : Christopher Dodds

Download or read book Oxford Textbook of Anaesthesia for the Elderly Patient written by Christopher Dodds and published by OUP Oxford. This book was released on 2014-03-27 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the global population lives to an increasing older age, there is a need to research, develop and deliver appropriate anaesthesia and pain management care to these increasingly frail and vulnerable patients. This book provides a comprehensive and detailed overview of all aspects of anaesthesia for the elderly patient looking at the effect of ageing on the systems of the body and the role that age has on drug mechanisms. Designed for both consultants and traineeswho care for elderly patients, chapters address the clinical management of the older patient in pain, trauma, intensive care as well as anaesthesia for all aspects of surgery. The expert author team use their experience to provide a practical and stimulating book which informs everyday clinical activity and explores the unanswered questions which face anaesthetists in this changing patient population. This book will give all consultants and trainees a thorough grounding in this growing and demanding area of anaesthetic practice.

The New Parkinson's Disease Treatment Book

Author : J. Eric Ahlskog, PhD, MD
Publisher : Oxford University Press
ISBN 13 : 0190231882
Total Pages : 544 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis The New Parkinson's Disease Treatment Book by : J. Eric Ahlskog, PhD, MD

Download or read book The New Parkinson's Disease Treatment Book written by J. Eric Ahlskog, PhD, MD and published by Oxford University Press. This book was released on 2015-08-03 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental guide to the most effective treatments for Parkinson's Disease, from a Mayo Clinic doctor with thirty years of clinical and research experience. In this second edition follow-up to the extremely successful first edition, Dr. Ahlskog draws on thirty years of clinical experience to present the definitive guide to dealing with all aspects of Parkinson's Disease, from treatment options and side effects to the impact of the disease on caregivers and family. Dr. Ahlskog's goal is to educate patients so that they can better team up with their doctors to do battle with the disease, streamlining the decision-making process and enhancing their treatment. To do this, Dr. Ahlskog offers a gold mine of information, distilled from his years of experience treating people with Parkinson's at the Mayo Clinic. In addition to providing a comprehensive account of Parkinson's medications, this book also examines additional aspects of treatment, such as the role of nutrition, exercise, and physical therapy. Although many commendable texts have been written on the subject of Parkinson's Disease, their discussions of treatment have not been in depth. Dr. Ahlskog sifts through aspects of the disease in order to give the reader a comprehensive sense of Parkinson's and the best available treatment options. With a broader understanding of the disease and the available options, patients are able to make more informed choices, and doctors are able to provide more tailored care. This book delivers hopeful, helpful, and extensive information to all parties concerned: patients, caregivers, and doctors. The ultimate guide to symptoms and treatment, this thoroughly updated second edition is the first place patients should turn for reliable, easy-to-grasp information on Parkinson's Disease.

The Clinical Science of Neurologic Rehabilitation

Author : Bruce H. Dobkin
Publisher : Contemporary Neurology
ISBN 13 : 0195150643
Total Pages : 616 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis The Clinical Science of Neurologic Rehabilitation by : Bruce H. Dobkin

Download or read book The Clinical Science of Neurologic Rehabilitation written by Bruce H. Dobkin and published by Contemporary Neurology. This book was released on 2003 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work translates neuroscientific research to illuminate ongoing and future practices for the rehabilitation of patients with neurologic diseases. It dissects fundamental concepts to define what researchers must consider as they pursue best practices and areas ripe for exploration

Affective Neuroscience

Author : Jaak Panksepp
Publisher : Oxford University Press
ISBN 13 : 019802567X
Total Pages : 481 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Affective Neuroscience by : Jaak Panksepp

Download or read book Affective Neuroscience written by Jaak Panksepp and published by Oxford University Press. This book was released on 2004-09-30 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have argued that emotions, especially animal emotions, are illusory concepts outside the realm of scientific inquiry. However, with advances in neurobiology and neuroscience, researchers are demonstrating that this position is wrong as they move closer to a lasting understanding of the biology and psychology of emotion. In Affective Neuroscience, Jaak Panksepp provides the most up-to-date information about the brain-operating systems that organize the fundamental emotional tendencies of all mammals. Presenting complex material in a readable manner, the book offers a comprehensive summary of the fundamental neural sources of human and animal feelings, as well as a conceptual framework for studying emotional systems of the brain. Panksepp approaches emotions from the perspective of basic emotion theory but does not fail to address the complex issues raised by constructionist approaches. These issues include relations to human consciousness and the psychiatric implications of this knowledge. The book includes chapters on sleep and arousal, pleasure and fear systems, the sources of rage and anger, and the neural control of sexuality, as well as the more subtle emotions related to maternal care, social loss, and playfulness. Representing a synthetic integration of vast amounts of neurobehavioral knowledge, including relevant neuroanatomy, neurophysiology, and neurochemistry, this book will be one of the most important contributions to understanding the biology of emotions since Darwins The Expression of the Emotions in Man and Animals

Navigating Life with Amyotrophic Lateral Sclerosis

Author : Mark B. Bromberg
Publisher : Oxford University Press
ISBN 13 : 0190241624
Total Pages : 281 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Navigating Life with Amyotrophic Lateral Sclerosis by : Mark B. Bromberg

Download or read book Navigating Life with Amyotrophic Lateral Sclerosis written by Mark B. Bromberg and published by Oxford University Press. This book was released on 2017 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Navigating Life with Amyotrophic Lateral Sclerosis provides accessible, comprehensive, and up-to-date information about the challenges patients, family members, and caregivers face when confronted by ALS, a disease that affects approximately 5,600 Americans every year, with as many as 30,000 people managing the disease at any given time. ALS is a difficult disease for the patient and is also challenging for the caregiver and family as there are many questions, issues relating to care, and problems to manage. This guide covers all aspects of managing ALS, from the onset of symptoms, diagnosis, treatments, and coping strategies, to the use of home health care or hospice, and new research in the field. The book also sheds lights on difficult topics, such as end-of-life care and managing legal affairs. Navigating Life with Amyotrophic Lateral Sclerosis is unique because it covers two perspectives: one author is a neurologist with 30 years of experience treating ALS patients, and the other author experienced first-hand the issues in providing care for a parent with ALS. Formatted in a question-and-answer style, peppered throughout with patient stories, and with sections devoted to family members and caregivers, this compassionate resource provides guidance to those seeking to understand how to live with this disease.

Guide to Research Techniques in Neuroscience

Author : Matt Carter
Publisher : Academic Press
ISBN 13 : 0323915612
Total Pages : 416 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step

Headache

Author : Mervyn J. Eadie
Publisher : OUP USA
ISBN 13 : 0199860971
Total Pages : 322 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Headache by : Mervyn J. Eadie

Download or read book Headache written by Mervyn J. Eadie and published by OUP USA. This book was released on 2012-05-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Headache: Through the Centuries illuminates the history of headaches with a particular interest in how the disorder has been understood and treated since the earliest recorded accounts, dating from around 4000 BC. Different types of headache were being recognized as early as the 2nd century AD. Over the years, though, the classification of types of headache has changed so that headache patterns described in the past are often difficult to relate to present-day types of headache. Since that time, a great deal of material on the topic has become available, the full gamut of manifestations of the disorder has been described, and considerable insight into its mechanisms has been obtained, though no completely satisfactory explanation of the disorder has yet become available. Providing an extensive history and the development of our understanding of headache over the course of six millennia, Headache: Through the Centuries is thought-provoking and relevant reading for neurologists, medical historians, and anyone interested in headaches.

Deep Brain Stimulation Programming

Author : Erwin B. Montgomery, Jr., MD
Publisher : Oxford University Press
ISBN 13 : 0199890013
Total Pages : 257 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Deep Brain Stimulation Programming by : Erwin B. Montgomery, Jr., MD

Download or read book Deep Brain Stimulation Programming written by Erwin B. Montgomery, Jr., MD and published by Oxford University Press. This book was released on 2010-04-13 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep Brain Stimulation (DBS) is a remarkable therapy for an expanding range of neurological and psychiatric disorders. In many cases it is better than best medical therapy and succeeds even when brain transplants fail. Yet despite the remarkable benefits, many physicians and healthcare professionals seem hesitant to embrace this therapy. Post-operative programming of the DBS systems seems unfamiliar, even mysterious, and is viewed as difficult and time consuming. However, DBS programming is rational and can be efficient and effective if one understands the basing underlying concepts of electronics, electrophysiology, and the relevant regional anatomy. Even these principles can be relatively easy to grasp. The book helps the reader to obtain an intuitive understanding of the basic principles of electronics, electrophysiology and the relevant regional anatomy through the use of readily understood metaphors and numerous illustrations. In addition a number of tools are provided including algorithms to ensure efficient and thorough programming. Forms are provided to help with documentation. In addition, DBS related research provides a remarkable tool to understand how the brain works and what happens in diseases such as Parkinson's disease. Already long cherished theories of the pathophysiology of Parkinson's disease must be abandoned. Indeed, these DBS derived insights suggest fundamental revisions of theories of brain function are in order. The book provides an introduction to where some of the new theories may lead particularly with the growing awareness of the importance of oscillations in the brain's activities. The brain has more in common with electrical devices, such as computers, than it does to a stew of chemicals. DBS operates at the electrical level in the brain, which is fundamental to how the brain creates, manipulates and conveys information and may indeed be fundamental to the misinformation the results in the dysfunction related to disorders of the brain. For downloadable forms and other relevant material, please visit: http://www.uab.edu/DBS_PrinciplesAndPractice

Concussion Care Manual

Author : David L. Brody
Publisher : Oxford University Press, USA
ISBN 13 : 0190054794
Total Pages : 257 pages
Book Rating : 4.1/5 (9 download)

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Book Synopsis Concussion Care Manual by : David L. Brody

Download or read book Concussion Care Manual written by David L. Brody and published by Oxford University Press, USA. This book was released on 2019 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is hard to find a medical condition that has as much media attention as concussion. With growing interest in concussion care by the NFL, NHL, NBA, and many other sports organizations, the military, and by regular patients, the number of concussion care providers has rapidly increased. Concussion Care Manual, Second Edition is the perfect step-by-step concussion management guide for clinicians, coaches, and even parents of athletic children. This pocket-sized volume discusses how to manage a variety of complexities associated with concussions including proper diagnosis, management strategies, headaches, anxiety and depression, PTSD, dizziness, fatigue, and changes to mood, balance, personality, and sleep. This book also covers the essential elements on how to set up and run a concussion clinic, focusing on the administrative need-to-know. A much-needed list of references, scales, and resources are provided at the end of the book for further investigation. New to the Second EditionEL -Fully revised based on the most up-to-date research in the field across disciplines - Evidence-based, this new edition summarizes what works and what doesn't from recent clinical trials and real world concussion care experience -Provides step by step guidance on how to provide appropriate active management when treating concussion

Pain Patients: Traits and Treatment

Author : Richard A. Sternbach
Publisher :
ISBN 13 :
Total Pages : 160 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pain Patients: Traits and Treatment by : Richard A. Sternbach

Download or read book Pain Patients: Traits and Treatment written by Richard A. Sternbach and published by . This book was released on 1974 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Behavioral and Psychopharmacologic Pain Management

Author : Michael H. Ebert
Publisher : Cambridge University Press
ISBN 13 : 113949354X
Total Pages : 507 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Behavioral and Psychopharmacologic Pain Management by : Michael H. Ebert

Download or read book Behavioral and Psychopharmacologic Pain Management written by Michael H. Ebert and published by Cambridge University Press. This book was released on 2010-11-25 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is the most common symptom bringing a patient to a physician's attention. Physicians training in pain medicine may originate from different disciplines and approach the field with varying backgrounds and experience. This book captures the theory and evidence-based practice of behavioral, psychotherapeutic and psychopharmacological treatments in modern pain medicine. The book's contributors span the fields of psychiatry, psychology, anesthesia, neurology, physical medicine and rehabilitation, and nursing. Thus the structure and content of the book convey the interdisciplinary approach that is the current standard for the successful practice of pain management. The book is designed to be used as a text for training fellowships in pain medicine, as well as graduate courses in psychology, nursing, and other health professions.

Inventing Pain Medicine

Author : Isabelle Baszanger
Publisher :
ISBN 13 : 9780813525013
Total Pages : 348 pages
Book Rating : 4.5/5 (25 download)

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Book Synopsis Inventing Pain Medicine by : Isabelle Baszanger

Download or read book Inventing Pain Medicine written by Isabelle Baszanger and published by . This book was released on 1998 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is a pervasive subject in our culture--especially as something to be combatted and conquered. One need only open a magazine or turn on the radio or television to become aware of this fact. But is the widespread interest in pain merely a passing fad or does it reflect the emergence of a new relationship between pain and medicine? Inventing Pain Medicine explores the current state of pain medicine against the background of its historical development. Based on extensive field research, Isabelle Baszanger's study outlines the first tentative steps to control pain taken in the last years of World War II when a young American anesthesiologist, John J. Bonica, made alleviating the pain of wounded soldiers his mission. Baszanger traces Bonica's protracted pioneering struggle for recognition of pain as worthy of medical attention in itself, for a definition of pain as more than a diagnostic tool, including differentiation of types of pain and modes of treatment, and for the establishment of specialized multidisciplinary pain clinics. Baszanger also provides an in-depth comparative analysis of the divergent approaches toward pain and its treatment at two clinics in France today, taking into account her observations at consultation sessions as well as many interviews with physicians, clinic staff, and patients. Her ethnographic inquiries are always anchored in socio-historical reflections on the social and conceptual transformations that were necessary to make the invention of pain medicine possible. A pathbreaking effort, this book goes a long way to explain why sufferers of chronic pain had to wait until the end of the twentieth century to find physicians and clinics specializing in the alleviation of their condition.