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Cancer 1999
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Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher : ISBN 13 : Total Pages :332 pages Book Rating :4.3/5 (91 download)
Book Synopsis Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer Epidemiology by : Isabel dos Santos Silva
Download or read book Cancer Epidemiology written by Isabel dos Santos Silva and published by IARC. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A basic textbook addressed to medical and public health students, clinicians, health professionals, and all others seeking to understand the principles and methods used in cancer epidemiology. Written by a prominent epidemiologist and experienced teacher at the London School of Hygiene and Tropical Medicine, the text aims to help readers become competent in the use of basic epidemiological tools and capable of exercising critical judgment when assessing results reported by others. Throughout the text, a lively writing style and numerous illustrative examples, often using real research data, facilitate an easy understanding of basic concepts and methods. Information ranges from an entertaining account of the origins of epidemiology, through advice on how to overcome some of the limitations of survival analysis, to a checklist of questions to ask when considering sources of bias. Although statistical concepts and formulae are presented, the emphasis is consistently on the interpretation of the data rather than on the actual calculations. The text has 18 chapters. The first six introduce the basic principles of epidemiology and statistics. Chapters 7-13 deal in more depth with each of the study designs and interpretation of their findings. Two chapters, concerned with the problems of confounding and study size, cover more complex statistical concepts and are included for advanced study. A chapter on methodological issues in cancer prevention gives examples of epidemiology's contribution to primary prevention, screening and other activities for early detection, and tertiary prevention. The concluding chapters review the role of cancer registries and discuss practical considerations that should be taken into account in the design, planning, and conduct of any type of epidemiological research.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Epidemiology of Childhood Cancer by : Julian Little
Download or read book Epidemiology of Childhood Cancer written by Julian Little and published by . This book was released on 1999 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second commonest cause of death, after accidents, among children in developed countries, while in developing countries, improvements in the control of communicable diseases and the occurrence of premature delivery may lead to the emergence of cancer in children as a greater public health problem than in the past. The rationale for considering childhood cancers separately from cancers in adults in that there are differences in the sites of occurrence, in the histological appearance and in their clinical behavior. This book reviews the epidemiology of specific types of childhood cancer to mid-1997. The scale of the problem is first reviewed in a major compilation of data on the descriptive epidemiology of childhood cancer, then separate chapters describe studies of the different postulated causal factors and summarize what can be concluded from them.
Book Synopsis The Unequal Burden of Cancer by : Institute of Medicine
Download or read book The Unequal Burden of Cancer written by Institute of Medicine and published by National Academies Press. This book was released on 1999-06-11 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: We know more about cancer prevention, detection, and treatment than ever beforeâ€"yet not all segments of the U.S. population have benefited to the fullest extent possible from these advances. Some ethnic minorities experience more cancer than the majority population, and poor peopleâ€"no matter what their ethnicityâ€"often lack access to adequate cancer care. This book provides an authoritative view of cancer as it is experienced by ethnic minorities and the medically underserved. It offers conclusions and recommendations in these areas: Defining and understanding special populations, and improving the collection of cancer-related data. Setting appropriate priorities for and increasing the effectiveness of specific National Institutes of Health (NIH) research programs, to ensure that special populations are represented in clinical trials. Disseminating research results to health professionals serving these populations, with sensitivity to the issues of cancer survivorship. The book provides background data on the nation's struggle against cancer, activities and expenditures of the NIH, and other relevant topics.
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :World Health Organization ISBN 13 : Total Pages :696 pages Book Rating :4.3/5 (91 download)
Book Synopsis Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine
Book Synopsis NCI Fact Book by : National Cancer Institute (U.S.)
Download or read book NCI Fact Book written by National Cancer Institute (U.S.) and published by . This book was released on 1979 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Health Consequences of Involuntary Exposure to Tobacco Smoke by :
Download or read book The Health Consequences of Involuntary Exposure to Tobacco Smoke written by and published by . This book was released on 2006 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Surgeon General's report returns to the topic of the health effects of involuntary exposure to tobacco smoke. The last comprehensive review of this evidence by the Department of Health and Human Services (DHHS) was in the 1986 Surgeon General's report, The Health Consequences of Involuntary Smoking, published 20 years ago this year. This new report updates the evidence of the harmful effects of involuntary exposure to tobacco smoke. This large body of research findings is captured in an accompanying dynamic database that profiles key epidemiologic findings, and allows the evidence on health effects of exposure to tobacco smoke to be synthesized and updated (following the format of the 2004 report, The Health Consequences of Smoking). The database enables users to explore the data and studies supporting the conclusions in the report. The database is available on the Web site of the Centers for Disease Control and Prevention (CDC) at http://www.cdc.gov/tobacco.
Book Synopsis One Renegade Cell by : Robert A Weinberg
Download or read book One Renegade Cell written by Robert A Weinberg and published by Basic Books. This book was released on 2008-08-04 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured. Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation. This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.
Book Synopsis U.S. Predicted Cancer Incidence, 1999 by : Linda Williams Pickle
Download or read book U.S. Predicted Cancer Incidence, 1999 written by Linda Williams Pickle and published by . This book was released on 2003 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis To Err Is Human by : Institute of Medicine
Download or read book To Err Is Human written by Institute of Medicine and published by National Academies Press. This book was released on 2000-03-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts estimate that as many as 98,000 people die in any given year from medical errors that occur in hospitals. That's more than die from motor vehicle accidents, breast cancer, or AIDSâ€"three causes that receive far more public attention. Indeed, more people die annually from medication errors than from workplace injuries. Add the financial cost to the human tragedy, and medical error easily rises to the top ranks of urgent, widespread public problems. To Err Is Human breaks the silence that has surrounded medical errors and their consequenceâ€"but not by pointing fingers at caring health care professionals who make honest mistakes. After all, to err is human. Instead, this book sets forth a national agendaâ€"with state and local implicationsâ€"for reducing medical errors and improving patient safety through the design of a safer health system. This volume reveals the often startling statistics of medical error and the disparity between the incidence of error and public perception of it, given many patients' expectations that the medical profession always performs perfectly. A careful examination is made of how the surrounding forces of legislation, regulation, and market activity influence the quality of care provided by health care organizations and then looks at their handling of medical mistakes. Using a detailed case study, the book reviews the current understanding of why these mistakes happen. A key theme is that legitimate liability concerns discourage reporting of errorsâ€"which begs the question, "How can we learn from our mistakes?" Balancing regulatory versus market-based initiatives and public versus private efforts, the Institute of Medicine presents wide-ranging recommendations for improving patient safety, in the areas of leadership, improved data collection and analysis, and development of effective systems at the level of direct patient care. To Err Is Human asserts that the problem is not bad people in health careâ€"it is that good people are working in bad systems that need to be made safer. Comprehensive and straightforward, this book offers a clear prescription for raising the level of patient safety in American health care. It also explains how patients themselves can influence the quality of care that they receive once they check into the hospital. This book will be vitally important to federal, state, and local health policy makers and regulators, health professional licensing officials, hospital administrators, medical educators and students, health caregivers, health journalists, patient advocatesâ€"as well as patients themselves. First in a series of publications from the Quality of Health Care in America, a project initiated by the Institute of Medicine
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :World Health Organization ISBN 13 : Total Pages :692 pages Book Rating :4.3/5 (91 download)
Book Synopsis Hormonal Contraception and Post-menopausal Hormonal Therapy by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Hormonal Contraception and Post-menopausal Hormonal Therapy written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluates evidence for an increased risk of cancer in women using combined oral contraceptives, progestogen-only hormonal contraceptives, post-menopausal estrogen therapy, and post-menopausal estrogen-progestogen therapy. Although the carcinogenicity of these preparations has been extensively investigated, the book stresses the many complex methodological issues that must be considered when interpreting findings and weighing results. Evidence of an association between use of these preparations and positive effects on health, including a reduced risk of some cancers, is also critically assessed. The first and most extensive monograph evaluates evidence of an association between the use of combined oral contraceptives and cancer at nine sites. Concerning breast cancer, the evaluation concludes that, even if the association is causal, the excess risk for breast cancer associated with patterns of use that are typical today is very small. Studies of predominantly high-dose preparations found an increased risk of hepatocellular carcinoma in the absence of hepatitis viruses. Citing these findings, the evaluation concludes that there is sufficient evidence in humans for the carcinogenicity of combined oral contraceptives. The evaluation also found sufficient evidence for the carcinogenicity of some, but not all, combined preparations in animals. Combined oral contraceptives were classified as carcinogenic to humans. The evaluation also cites conclusive evidence that these agents have a protective effect against cancers of the ovary and endometrium. Progestogen-only contraceptives are evaluated in the second monograph, which considers the association with cancer at six sites. The evaluation found no evidence of an increased risk for breast cancer. Although the evaluation found sufficient evidence in animals for the carcinogenicity of medroxyprogesterone acetate, evidence for the carcinogenicity of progestogen-only contraceptives in humans was judged inadequate. Progestogen-only contraceptives were classified as possibly carcinogenic to humans. The third monograph, on post-menopausal estrogen therapy, considers evidence of an association with cancer at eight sites. Findings from a large number of epidemiological studies indicate a small increase in the risk of breast cancer in women who have used these preparations for five years or more. Studies consistently show an association between use of post-menopausal estrogen therapy and an increased risk for endometrial cancer. Data on the association with other cancers were either inconclusive or suggested no effect on risk. The evaluation concludes that post-menopausal estrogen therapy is carcinogenic to humans. The final monograph evaluates the association between the use of post-menopausal estrogen-progestogen therapy and cancer at four sites. The evaluation of limited data on breast cancer found an increased relative risk observed with long-term use. Data were judged insufficient to assess the effects of past use and of different progestogen compounds, doses, and treatment schedules. For endometrial cancer, the evaluation found an increase in risk relative to non-users when the progestogen was added to the cycle for 10 days or fewer. Post-menopausal estrogen-progestogen therapy was classified as possibly carcinogenic to humans. Concerning post-menopausal therapy in general, the book notes that evidence of carcinogenic risks must be placed in perspective of potential benefits. The prevention of osteoporotic fractures is cited as the best-established benefit. Evidence also suggests that estrogen prevents heart disease and may prevent memory loss and dementia.
Download or read book Her-2 written by Robert Bazell and published by Random House. This book was released on 2011-04-27 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.
Book Synopsis Cancer in Thailand by : World Health Organization
Download or read book Cancer in Thailand written by World Health Organization and published by . This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents data on cancer incidence gathered from five population-based cancer registries in different regions of Thailand and compares these data with data on cancer incidence from other parts of the world. Apart from offering a comprehensive overview of cancer incidence in Thailand, the book uncovers a number of geographical differences in incidence, suggesting important behavioral, environmental, or industrial risk factors that deserve further study. Survival data from two registries are also presented and discussed. The opening chapters provide background information about the country and its population, describe the sources of data maintained in the five registries, and discuss the methods of data coding and analysis used in the study. Against this background, results are presented separately for each of 15 cancers and for childhood cancer. For each cancer, the number of cases registered in 1992-1994 is shown by sex, with age-specific incidence rates and some summary rates. The study uncovered striking geographical variations in the incidence of specific cancers. For the country as a whole, the highest incidences were found for cancers of the liver, lung, colon and rectum, oral cavity, bladder, stomach, leukaemia, non-Hodgkin lymphoma, and cancers of the nasopharynx and oesophagus. For each cancer, data are set out in numerous tables, compared with findings from other countries and discussed in terms of possible risk factors. Primary cancer of the liver was identified as the leading cancer of males and the third most important cancer in females.
Download or read book Cancer 1999 written by Sydney Omarr and published by Signet Book. This book was released on 1998-06-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bone and Soft Tissue Tumors by : Mario Campanacci
Download or read book Bone and Soft Tissue Tumors written by Mario Campanacci and published by Springer. This book was released on 2013-12-11 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an extraordinary book by an extraordinary author. Mario Campa nacci first published three volumes on musculoskeletal neoplasms and other tu mor-like processes in hone and soft parts in Italian in 1981-1985. This book is an update and expansionofthat book, published for the firsttime in English. In this book Dr. Campanacci brings to the readers the vast experience in musculoskel etal oncology of the Rizzoli Orthopaedic Institute in Bologna where he has been head of the Oncology Unit for many years. As such, he has had at his disposal the patient records, radiographs and pathologic material dating back to 1905. In fact, a visitor to the Institute will be shown the radiograph made of the first tumor case on records-that of a giant cell tumor of the distal femur. The wealth of cli nical material that has accumulated at the Rizzoli Institute, with exquisite docu mentation and maintenance is a unique resource and testimonial to not only the author but his predecessors. Under Dr. Campanacci's leadership, the Institute has provided care to the majority of patients with neoplasms throughout Italy. Over the past two decades a treatment team with extraordinary ability in radi ology, imaging, pathology, chemotherapy, as well as orthopedic surgery has been assembled.
Book Synopsis Cancer 1999 (Book Co Ed) by : Random House
Download or read book Cancer 1999 (Book Co Ed) written by Random House and published by . This book was released on 1998-07-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
