Calcium Signaling And Nervous System

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Calcium Signaling and Nervous System

Author : Victor V. Chaban
Publisher : Nova Science Publishers
ISBN 13 : 9781536184211
Total Pages : 107 pages
Book Rating : 4.1/5 (842 download)

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Book Synopsis Calcium Signaling and Nervous System by : Victor V. Chaban

Download or read book Calcium Signaling and Nervous System written by Victor V. Chaban and published by Nova Science Publishers. This book was released on 2020 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides comprehensive insights into emerging trends on calcium signaling in the nervous system from triggering signal transduction neuronal pathways to regulation of brain functions. Calcium signaling is one of the major coupling mechanism linking external stimuli with intracellular processes. Normal calcium signaling is important for functioning of all cells particularly neurons coupled to control mechanisms of the body inducing intra- and intercellular signaling and triggering biochemical cascade to control metabolism, gene expression, cell differentiation and apoptosis. The author, Dr. Victor V. Chaban is Professor of Medicine with dual appointment at Charles R. Drew University of Medicine and Science (CDU) and University of California Los Angeles (UCLA). Dr. Chaban completed his post-doctoral training in Neuroscience at UCLA and graduate studies in Clinical Research at CDU. He serves on National Institute of Health and several international study sections and holds U.S. Patents. Prof. Chaban is established expert, who contributed significantly to a better understanding of neuroplasticity and neurodegeneration associated with changes in calcium signaling. Calcium Signaling and Nervous System: Overview and Directions for Research gives an up to date account of changes in intracellular Ca2+ associated with primary afferents sensitization, neuronal and glial reorganization, neuroprotection and neurodegeneration. This book is recommended to scientists, healthcare providers, students and patients"--

The Endothelium

Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Neuromorphic Olfaction

Author : Krishna C. Persaud
Publisher : CRC Press
ISBN 13 : 1439871728
Total Pages : 237 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Neuromorphic Olfaction by : Krishna C. Persaud

Download or read book Neuromorphic Olfaction written by Krishna C. Persaud and published by CRC Press. This book was released on 2016-04-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Store-Operated Calcium Channels

Author :
Publisher : Academic Press
ISBN 13 : 0124079385
Total Pages : 307 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Store-Operated Calcium Channels by :

Download or read book Store-Operated Calcium Channels written by and published by Academic Press. This book was released on 2013-07-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject

Anatomy and Physiology

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Magnesium in the Central Nervous System

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Calcium Signalling and Disease

Author : Ernesto Carafoli
Publisher : Springer Science & Business Media
ISBN 13 : 1402061919
Total Pages : 591 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Calcium Signalling and Disease by : Ernesto Carafoli

Download or read book Calcium Signalling and Disease written by Ernesto Carafoli and published by Springer Science & Business Media. This book was released on 2007-09-29 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.

Neural Signaling

Author : Proceedings of the National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 030908279X
Total Pages : 231 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Neural Signaling by : Proceedings of the National Academy of Sciences

Download or read book Neural Signaling written by Proceedings of the National Academy of Sciences and published by National Academies Press. This book was released on 2002 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:

B Cell Receptor Signaling

Author : Tomohiro Kurosaki
Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 233 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis B Cell Receptor Signaling by : Tomohiro Kurosaki

Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

Brain Aging

Author : David R. Riddle
Publisher : CRC Press
ISBN 13 : 1420005529
Total Pages : 413 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Dendrites

Author : Greg Stuart
Publisher : Oxford University Press, USA
ISBN 13 : 0198566565
Total Pages : 578 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Dendrites by : Greg Stuart

Download or read book Dendrites written by Greg Stuart and published by Oxford University Press, USA. This book was released on 2007 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrites form the major receiving part of neurons. This text presents a survey of knowledge on dendrites, from their morphology and development, through to their electrical chemical, and computational properties.

Ion Channels in Health and Sickness

Author : Fatima Shad Kaneez
Publisher : BoD – Books on Demand
ISBN 13 : 1789842271
Total Pages : 204 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Ion Channels in Health and Sickness by : Fatima Shad Kaneez

Download or read book Ion Channels in Health and Sickness written by Fatima Shad Kaneez and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins.

Anatomy & Physiology

Author : Lindsay Biga
Publisher :
ISBN 13 : 9781955101158
Total Pages : pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Anatomy & Physiology by : Lindsay Biga

Download or read book Anatomy & Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text

Interrelations between Essential Metal Ions and Human Diseases

Author : Astrid Sigel
Publisher : Springer Science & Business Media
ISBN 13 : 9400775008
Total Pages : 603 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Interrelations between Essential Metal Ions and Human Diseases by : Astrid Sigel

Download or read book Interrelations between Essential Metal Ions and Human Diseases written by Astrid Sigel and published by Springer Science & Business Media. This book was released on 2014-01-27 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.

Integrative Aspects of Calcium Signalling

Author : Alexej Verkhratsky
Publisher : Springer Science & Business Media
ISBN 13 : 9780306460326
Total Pages : 440 pages
Book Rating : 4.4/5 (63 download)

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Book Synopsis Integrative Aspects of Calcium Signalling by : Alexej Verkhratsky

Download or read book Integrative Aspects of Calcium Signalling written by Alexej Verkhratsky and published by Springer Science & Business Media. This book was released on 1998-10-31 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is the first effort in a single volume to cover all of the integrative functions of calcium signalling - how changes in intracellular calcium coordinate a variety of coherent cellular responses. Written by a team of internationally established researchers, Integrative Aspects of Calcium Signalling provides the latest experimental data and concepts, bringing together a detailed analysis of the events, processes, and functions regulated by calcium signalling. A unique resource for professionals and students of physiology, biophysics, neurobiology, biochemistry, and all related fields.

Handbook of Neurochemistry

Author : Abel Lajtha
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (82 download)

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Book Synopsis Handbook of Neurochemistry by : Abel Lajtha

Download or read book Handbook of Neurochemistry written by Abel Lajtha and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Xenopus

Author : Kris Vleminckx
Publisher : Humana
ISBN 13 : 9781493987832
Total Pages : 0 pages
Book Rating : 4.9/5 (878 download)

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Book Synopsis Xenopus by : Kris Vleminckx

Download or read book Xenopus written by Kris Vleminckx and published by Humana. This book was released on 2018-08-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores techniques used to study and experiment with Xenopus in order to model or understand human disease. The chapters in this book cover topics such as implementation of CRISPR/Cas9 and TALEN in Xenopus from the design stage up to the genotyping stage; methods to explore generation of knock-in animals; cancer modelling and in vivo screening of congenital heart disease; electroporation; and phenotyping at the organismal level, cellular level, and proteome level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Xenopus: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this wide and developing field. This book will aid in keeping Xenopus at the forefront for biochemical, cell biological, and developmental studies and forward it as a preclinical disease model.