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Brain Energetics And Neuronal Activity
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Book Synopsis Brain Energetics and Neuronal Activity by : Robert G. Shulman
Download or read book Brain Energetics and Neuronal Activity written by Robert G. Shulman and published by John Wiley & Sons. This book was released on 2005-08-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states It provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders. Novel and potentially controversial Will inspire future research directions
Book Synopsis The link between brain energy homeostasis and neuronal activity by : Yuri Zilberter
Download or read book The link between brain energy homeostasis and neuronal activity written by Yuri Zilberter and published by Frontiers E-books. This book was released on with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is an extremely energy consuming part of the body, which makes it dangerously vulnerable to metabolic stress. It’s no wonder then that abnormalities of brain energy metabolism are becoming the usual suspects and a hallmark of many neurodegenerative diseases. The socioeconomic burden of these alone begs for urgent measures to be taken for better understanding both fundamental and applied problems of neuroenergetics and neuroprotection. For instance, brain imaging reveals that the diseased brains of Alzheimer’s patients cannot efficiently utilize the vital brain fuel, glucose. The resulting energy deficit causes neuronal hyperactivity, seizures and cognitive impairments. Administration of native energy substrates complementary to glucose is a logical (and attractive in its simplicity) approach in fighting the energy crisis in the brain*. The two closely related aspects of brain activity -- neuronal and metabolic – are currently considered to be of utmost importance in both fundamental and applied neuroscience. Although recently the studies of both brain activity and metabolism in normal conditions, under metabolic stress, and in neurodegenerative diseases have experienced significant progress, their overlapping areas deserve further clarification by joint efforts from experts in such fields as (1) energy demands, supplies, and efficiency at the cellular level: in neurons, glial elements, micro-vessels and in the process of their coordinated interactions; (2) specific roles of energy substrates in fine-tuning of the demand-supply mechanism in the condition of metabolic stress; and (3) the macro-level of energy homeostasis and dietary manipulations possible beneficial for neurodegenerative diseases. The result of combining into a coherent whole the recent findings in these fields will hopefully bring forward a broader view and better understanding of the knowledge continuum, which is under the threat of further fragmentation due to the unavoidable process of specialization in neuroscience. Current issue covers the three major groups of topics: 1. The Pros and Cons of studies of neuronal activity using brain slice preparations 2. The role of particular energy substrates in metabolic support of neuronal activity 3. The macro-level of energy homeostasis and the dietary manipulations that seem promising in prevention and correction of the diseases of brain energy metabolism.
Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Gary E. Gibson
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Gary E. Gibson and published by Springer Science & Business Media. This book was released on 2007-03-13 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brain Energy Metabolism by : Johannes Hirrlinger
Download or read book Brain Energy Metabolism written by Johannes Hirrlinger and published by Humana Press. This book was released on 2014-09-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultures which allow assessing of the properties and functions of a single brain cell type with many different types of analysis, however, at the expense of neglecting the interaction between cell types in the brain. On the other end, analysis in animals and humans in vivo is discussed, maintaining the full complexity of the tissue and the organism but making high demands on the methods of analysis. Written for the popular Neuromethods series, chapters include the kind of detailed description and key implementation advice that aims to support reproducible results in the lab. Meticulous and authoritative, Brain Energy Metabolism provides an ideal guide for researchers interested in brain energy metabolism with the hope of stimulating more research in this exciting and very important field.
Book Synopsis Neural Metabolism In Vivo by : In-Young Choi
Download or read book Neural Metabolism In Vivo written by In-Young Choi and published by Springer Science & Business Media. This book was released on 2012-03-14 with total page 1168 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter
Author :Francisco Gonzalez-Lima Publisher :Springer Science & Business Media ISBN 13 :1475799365 Total Pages :294 pages Book Rating :4.4/5 (757 download)
Book Synopsis Cytochrome Oxidase in Neuronal Metabolism and Alzheimer’s Disease by : Francisco Gonzalez-Lima
Download or read book Cytochrome Oxidase in Neuronal Metabolism and Alzheimer’s Disease written by Francisco Gonzalez-Lima and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on an international symposium titled "Cytochrome oxidase in energy metabolism and Alzheimer's disease," held as a satellite to the 27th meeting of the Society for Neuroscience, New Orleans, 1997. The symposium was dedicated in honor of Dr. Margaret T. T. Wong-Riley because, in our opinion, the cytochrome oxidase histo chemical method introduced by Dr. Wong-Riley in 1979 was the most significant break through to map energy metabolism in the entire brain since the 2-deoxyglucose method introduced by Dr. Louis Sokoloff and colleagues in 1977. Both of these metabolic map ping techniques have made monumental contributions to brain research by allowing an integral view of brain activity. They have also developed into various specialized tech niques, including applications to the human brain. One of these new applications, which is described in detail in this book, is the quantitative cytochrome oxidase cytochemical method used to study Alzheimer's disease. The objective of this book is to describe the role of cytochrome oxidase in neuronal metabolism and Alzheimer's disease. Whether genetic or environmental, the pathogenesis of Alzheimer's disease involves a cascade of multiple intracellular events, eventually re sulting in failure of oxidative energy metabolism. Could impairment of cytochrome oxi dase in energy metabolism initiate the degenerative process? Cytochrome oxidase function and dysfunction are discussed in relationship to neuronal energy metabolism, neurodegen eration, and Alzheimer's disease. The book is made up of 10 chapters, divided into three major parts.
Book Synopsis Handbook of Neurochemistry by : Abel Lajtha
Download or read book Handbook of Neurochemistry written by Abel Lajtha and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brain Energy Metabolism by : Bo K. Siesjö
Download or read book Brain Energy Metabolism written by Bo K. Siesjö and published by John Wiley & Sons. This book was released on 1978 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolism of the Nervous System by : Derek Richter
Download or read book Metabolism of the Nervous System written by Derek Richter and published by Elsevier. This book was released on 2013-10-22 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism of the Nervous System contains the proceedings of the 2nd International Neurochemical Symposium, held at Aarhus, Denmark, in July 1956. The book discusses the molecular structure and morphology of the adult nervous tissue; the chemical composition and cytochemical localization of adult nervous tissue; and the permeability and blood-brain barrier. The text also describes topics on electrolytes and nervous conduction; the metabolism of isolated nerve and ganglion; and the metabolism of the brain in vivo. The metabolism of brain tissue preparations in vitro; energy metabolism and coenzymes in relation to the nervous system; and lipid and fatty acid metabolism are also considered. The book further tackles nucleic acid metabolism; protein and amino acid metabolism; and cholinergic and non-cholinergic transmission. The text also discusses other pharmacologically active compounds related to the adult nervous tissue.
Book Synopsis In Vivo Optical Imaging of Brain Function, Second Edition by : Ron D. Frostig
Download or read book In Vivo Optical Imaging of Brain Function, Second Edition written by Ron D. Frostig and published by CRC Press. This book was released on 2009-05-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.
Author :Proceedings of the National Academy of Sciences Publisher :National Academies Press ISBN 13 :030909030X Total Pages :175 pages Book Rating :4.3/5 (9 download)
Book Synopsis (NAS Colloquium) Neuroimaging of Human Brain Function by : Proceedings of the National Academy of Sciences
Download or read book (NAS Colloquium) Neuroimaging of Human Brain Function written by Proceedings of the National Academy of Sciences and published by National Academies Press. This book was released on 1998-01-01 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The colloquium on "Imaging of Cognitive Function" speaks to the many audiences whose interests relate to efforts to map cognitive processes in the human brain. There are things of great interest in this collection of papers for specialists in cognition and neuroscience and imaging science as well as in disciplines interested in human development through education and training and others with intrinsic interest in the latest information on how the human brain supports thought. The papers were presented at a meeting sponsored by the National Academy of Sciences in its western home the Beckman Center at the University of California, Irvine.
Book Synopsis Neuroscience in the 21st Century by : Donald W. Pfaff
Download or read book Neuroscience in the 21st Century written by Donald W. Pfaff and published by Springer. This book was released on 2016-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Book Synopsis Glial-Neuronal Signaling in Neuroendocrine Systems by : Jeffrey G. Tasker
Download or read book Glial-Neuronal Signaling in Neuroendocrine Systems written by Jeffrey G. Tasker and published by Springer Nature. This book was released on 2021-04-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Cellular Metabolism and Related Disorders by : Jesmine Khan
Download or read book Cellular Metabolism and Related Disorders written by Jesmine Khan and published by BoD – Books on Demand. This book was released on 2020-07-15 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with a vital topic: metabolism in the cells of the body and various disorders due to its imbalance and/or diseases that disrupt the metabolism of the body. The objective of this book was to collect and compile up-to-date information from reputed researchers in their respective fields to disseminate the latest information about topics that have profound effects on the metabolic processes in the body including insulin resistance, diabetes mellitus, hypothyroidism, metabolic syndrome, glycogen storage disease, and the urea cycle disorder. In total, there are 12 chapters in this book in which the authors have shared their research findings and real-life experiences in managing their patients.
Book Synopsis Optical Imaging of Brain Function and Metabolism 2 by : Arno Villringer
Download or read book Optical Imaging of Brain Function and Metabolism 2 written by Arno Villringer and published by Boom Koninklijke Uitgevers. This book was released on 1997-06-30 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the latest developments in optical imaging of the brain.
Book Synopsis Introduction to Functional Magnetic Resonance Imaging by : Richard B. Buxton
Download or read book Introduction to Functional Magnetic Resonance Imaging written by Richard B. Buxton and published by Cambridge University Press. This book was released on 2009-08-27 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a useful introductory book on a technique that has revolutionized neuroscience, specifically cognitive neuroscience. Functional magnetic resonance imaging (fMRI) has now become the standard tool for studying the brain systems involved in cognitive and emotional processing. It has also been a major factor in the consilience of the fields of neurobiology, cognitive psychology, social psychology, radiology, physics, mathematics, engineering, and even philosophy. Written and edited by a clinician-scientist in the field, this book remains an excellent user's guide to t
Book Synopsis Culture, Mind, and Brain by : Laurence J. Kirmayer
Download or read book Culture, Mind, and Brain written by Laurence J. Kirmayer and published by Cambridge University Press. This book was released on 2020-09-24 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent neuroscience research makes it clear that human biology is cultural biology - we develop and live our lives in socially constructed worlds that vary widely in their structure values, and institutions. This integrative volume brings together interdisciplinary perspectives from the human, social, and biological sciences to explore culture, mind, and brain interactions and their impact on personal and societal issues. Contributors provide a fresh look at emerging concepts, models, and applications of the co-constitution of culture, mind, and brain. Chapters survey the latest theoretical and methodological insights alongside the challenges in this area, and describe how these new ideas are being applied in the sciences, humanities, arts, mental health, and everyday life. Readers will gain new appreciation of the ways in which our unique biology and cultural diversity shape behavior and experience, and our ongoing adaptation to a constantly changing world.
