Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Biotechnologies For Gene Therapy
Download Biotechnologies For Gene Therapy full books in PDF, epub, and Kindle. Read online Biotechnologies For Gene Therapy ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Biotechnologies for Gene Therapy by : Yang H. Yun
Download or read book Biotechnologies for Gene Therapy written by Yang H. Yun and published by Springer Nature. This book was released on 2022-06-02 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders. It also features innovations of the delivery methods for nucleic acids ranging from nanodevices made from DNA and pseudo amino acids to viral vectors. This is an ideal book for academics, clinicians, and students interested in gene therapy.
Book Synopsis BIOTECHNOLOGY - Volume XI by : Horst W. Doelle
Download or read book BIOTECHNOLOGY - Volume XI written by Horst W. Doelle and published by EOLSS Publications. This book was released on 2009-11-16 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Encyclopedia of Biotechnology is a component of the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Biotechnology draws on the pure biological sciences (genetics, animal cell culture, molecular biology, microbiology, biochemistry, embryology, cell biology) and in many instances is also dependent on knowledge and methods from outside the sphere of biology (chemical engineering, bioprocess engineering, information technology, biorobotics). This 15-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the field and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.
Book Synopsis A Guide To Human Gene Therapy by : Roland W Herzog
Download or read book A Guide To Human Gene Therapy written by Roland W Herzog and published by World Scientific. This book was released on 2010-06-18 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy — though still in its infancy — remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ('vector') to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study basic biological aspects of disease. Correction of disease in animal studies, is steadily gaining ground, highlighting the immense potential of gene therapy in the medical profession.This book will cover topics that are at the forefront of biomedical research such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases and disorders of the central nervous system. Leading experts on the respective vector or disease will contribute the individual chapters and explain cutting-edge technologies. It also gives a broad overview of the most important gene transfer vectors and most extensively studied target diseases. This comprehensive guide is therefore a must-read for anyone in the biotechnology, biomedical or medical industries seeking to further their knowledge in the area of human gene therapy.
Book Synopsis Gene Therapy and Gene Delivery Systems by : David V. Schaffer
Download or read book Gene Therapy and Gene Delivery Systems written by David V. Schaffer and published by Springer Science & Business Media. This book was released on 2005-12-20 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 D.V. Schaffer, W. Zhou: Gene Therapy as Future Human Therapeutics.- 2 J. Heidel, S. Mishra, M.E. Davis: Molecular Conjugates.- 3 M. Manthorpe, P. Hobart, G. Hermanson, M. Ferrari, A. Geall, B. Goff, A. Rolland: Plasmid Vaccines and Therapeutics: From Design to Applications.- 4 S.R. Little, R. Langer: Non-Viral Delivery of Cancer Genetic Vaccines.- 5 J.C. Grieger, R.J. Samulski: Adeno-Associated Virus as a Gene Therapy Vector: Vector Development, Production and Clinical Applications.- 6 J.H. Yu, D.V. Schaffer: Advanced Targeting Strategies for Murine Retroviral and Adeno-Associated Viral Vectors.- 7 N. Loewen, E.M. Poeschla: Lentiviral Vectors.- 8 N.E. Altaras, J.G. Aunins, R.K. Evans, A. Kamen, J.O. Konz, J.J. Wolf: Production and Formulation of Adenovirus Vectors.-
Book Synopsis Biotechnology in the Modern Medicinal System by : Rajesh K. Kesharwani
Download or read book Biotechnology in the Modern Medicinal System written by Rajesh K. Kesharwani and published by CRC Press. This book was released on 2021-12-23 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology in the Modern Medicinal System: Advances in Gene Therapy, Immunotherapy, and Targeted Drug Delivery presents an informative picture of the state-of-the-art research and development of actionable knowledge in medical biotechnology, specifically involving gene therapy, immunotherapy, and targeted drug delivery systems. The book includes novel approaches for therapy of various ailments and the real-world challenges and complexities of the current drug delivery methodologies and techniques. The volume helps to bridge the gap between academic research and real-time clinical applications and the needs of medical biotechnology methods. This edited book also provides a detailed application of medical biotechnology in drug discovery and the treatment of various deadly diseases. Chapters discuss targeted drug delivery to specific sites to avoid possible entry to non-targeted sites, minimizing adverse effects. The volume provides information about the roles of alternative routes of drug targeting, like intranasal and transdermal, resulting in improving patient compliance. Targeted drug delivery is explored for several health issues, such as neurodegenerative disorders, cancer, malaria, and hemoglobin disorders. Also considered is the role of genes in various genetic diseases and gene therapy, and immunogene therapy as alternative approaches to conventional cancer therapy. Finally, the book investigates the important role of computers in biotechnology to accelerate research and development in the modern medicinal field for better and optimum results. Studies show that significant improvement has been observed in the development of a faster and less invasive diagnostic system for the treatment of diseases by utilizing both artificial intelligence (AI) and biotechnology. This valuable volume provides a wealth of information that will be valuable to scientists and researchers, faculty, and students.
Download or read book Gene Therapy written by Mauro Giacca and published by Springer Science & Business Media. This book was released on 2010-11-01 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.
Download or read book Gene Therapy written by Joseph Panno and published by Infobase Publishing. This book was released on 2005 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many diseases are caused by a simple point mutation.
Book Synopsis Gene Therapy: Prospective Technology assessment in its societal context by : Jörg Niewöhner
Download or read book Gene Therapy: Prospective Technology assessment in its societal context written by Jörg Niewöhner and published by Elsevier. This book was released on 2011-08-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents work that has been conducted as part of the research project "Discourse on ethical questions of biomedicine" of the interdisciplinary Working Group Bioethics and Science Communication at the Max-Delbrueck-Center for Molecular Medicine (MDC)in Berlin-Buch, Germany. This book offers ground-breaking ideas on how the daily interworking of cutting-edge biomedical research assess the broader social context and its communication to stakeholders and the public. Editors cover three aspects: Scientific, Ethical and Legal, and Perception and Communication. This work establishes an international and interdisciplinary network of excellent researchers at the beginning of their careers, who brilliantly integrate their work into the different perspectives on gene therapy from the natural and social sciences, as well as the humanities and law. * Discusses biological and cellular barriers limiting the clinical application of nonviral gene deliverysystems* Addresses such questions as: Does patent granting hinder the development of Gene Therapy products?* Offers insight in the future of public perception of gene therapy in Europe* Provides details on how to communicate risks in gene therapy
Book Synopsis Molecular Biotechnology by : Sunil Maulik
Download or read book Molecular Biotechnology written by Sunil Maulik and published by John Wiley & Sons. This book was released on 1996-10-09 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: MOLECULAR BIOTECHNOLOGY Therapeutic Applications and Strategies SUNIL MAULIK and SALIL D. PATEL Recombinant DNA technology, or genetic engineering, has revolutionized our understanding of life at the molecular level-giving us a detailed picture of the living cell's functions and spawning diverse biotechnologies that use molecules, cells, tissues, and even entire organisms. This introduction to molecular biotechnology is a practical, up-to-date guide to this rapidly growing field. Based on courses taught by the authors to biotechnology professionals, Molecular Biotechnology: Therapeutic Applications and Strategies applies the principles of modern biotechnology to advances and trends in the development of therapeutic strategies and approaches to disease prevention and intervention. By focusing on select applications and strategies, this volume exemplifies the convergence of biological, chemical, and informational advances in the discovery of novel targets and drugs. This multidisciplinary approach, essential to the development of commercial therapeutic molecules, includes carefully selected real-world examples from the pharmaceutical and biotechnology industries. Specific topics covered include: * Genome Based Medicine and the Human Genome Project * Human Gene Therapy * Combinatorial Chemistry * Rational Drug Design * Reengineering the Immune System User-friendly and organized for maximum understanding, Molecular Biotechnology: Therapeutic Applications and Strategies is an excellent text/reference for biotechnology professionals, researchers, physicians, students, managers, industry analysts, and investors interested in learning more about the field of molecular biotechnology.
Book Synopsis A Special Report on Gene Therapy by : K. K. Jain
Download or read book A Special Report on Gene Therapy written by K. K. Jain and published by John Wiley & Sons. This book was released on 2000-04-14 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special report on Gene Therapy Companies by K.K. Jain provides an up-to-date overview of the gene therapy industry. It contains a wealth of very practical information on 105 companies. For each company, information is available on the people to contact, their contact details, a corporate history, the company's technologies and products, financial data, patents held, products in clinical trials, collaborations with other companies and selected publications from the company's scientists. Almost 200 companies were initially considered for inclusion but just over 100 companies were finally selected as they fulfilled the necessary criteria to be classified as a 'Gene Therapy Company,', defined broadly to include cell therapy companies. Not all of the companies devote their activity exclusively to gene therapy but they have sufficient relevance to be included. As part of this project, new companies were discovered that have not been reported in other publications or on the internet. Dr. Jain has spared no effort to ensure that the information is up-to-date and accurate at the time of publishing. In most instances, the information was reviewed by the companies to correct any outdated information or to add any complementary or recent information. In addition to the detailed descriptions of each company, the data is also presented in summary tabular form so that at a glance the reader can identify collaborations within the gene therapy industry, or determine which companies are pursuing strategies involving viral, non-viral or other approaches to gene therapy, and which diseases are being targetted. Given that much of the gene therapy research and development is currently being carried out within the industrial sector, it is important for scientists, managers and investors to have the relevant information at their fingertips. This special report provides that information in one accurate, easy to consult and up-to-date source.
Download or read book Engineering Health written by Lara Marks and published by Royal Society of Chemistry. This book was released on 2017-10-25 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology harnesses cellular and biochemical systems to advance knowledge of the molecular cause of disease and to provide new diagnostic tools and more precisely targeted drugs. Within a decade, global investment in medical biotechnology has increased more than ten-fold, resulting in therapies for previously untreatable conditions. But what exactly is biotechnology and what are its origins? What further benefits to human health could it offer in the future? Written in an accessible style, contributors to this book explore the history behind different biotechnology tools, how they are used, and how they are reshaping the future of diagnostics, therapeutics and vaccines. Among the technologies examined are genetic engineering, DNA sequencing, monoclonal antibodies, stem cells, gene therapy, cancer immunotherapy and the most recent newcomer - synthetic biology. Applying new biotechnologies in medicine is not without great challenges. As medicines shift from small organic molecules to large, complex structures, such as therapeutic proteins, drugs become difficult to make, administer and regulate. This book will intrigue anyone interested in medicine and how we have been, and may continue to, engineer better health for ourselves. Such changes have major implications for how and where drugs are manufactured, the cost of medicine and the ethics of how far society is prepared to go to combat disease.
Book Synopsis Emerging Trends in Cell and Gene Therapy by : Michael K. Danquah
Download or read book Emerging Trends in Cell and Gene Therapy written by Michael K. Danquah and published by Springer Science & Business Media. This book was released on 2013-06-14 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: · Biological aspects of stem cell sources, differentiation and engineering. · Application of microfluidics to study stem cell dynamics · Potential clinical application of stem cells and gene therapy to specific human disease. · Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. · Biomimetic multiscale topography for cell alignment.
Book Synopsis Gene and Cell Therapy by : Nancy Smyth Templeton
Download or read book Gene and Cell Therapy written by Nancy Smyth Templeton and published by CRC Press. This book was released on 2008-10-06 with total page 1154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the second edition of this book in 2004, gene therapy and cell therapy clinical trials have yielded some remarkable successes and some disappointing failures. Now in its third edition, Gene and Cell Therapy: Therapeutic Mechanisms and Strategies assembles many of the new technical advances in gene delivery, clinical applications, and new approaches to the regulation and modification of gene expression. New Topics Covered in this Edition: Gene and Cell Therapies for Diabetes and Cardiovascular Diseases Clinical Trials Human Embryonic Stem Cells Tissue Engineering Combined with Cell Therapies Novel Polymers Relevant Nanotechnologies SiRNA Therapeutic Strategies Dendrimer Technologies Comprised of contributions from international experts, this book begins with a discussion of delivery systems and therapeutic strategies, exploring retroviral vectors and adenovirus vectors, as well as other therapeutic strategies. The middle section focuses on gene expression and detection, followed by an examination of various therapeutic strategies for individual diseases, including hematopoietic disorders, cardiovascular conditions, cancer, diabetes, cystic fibrosis, neurological disorders, and childhood-onset blindness. The final section discusses recent clinical trials and regulatory issues surrounding the new technology. This compendium is assembled by noted molecular biologist and biochemist Nancy Smyth Templeton. Baylor College of Medicine and several other institutions have used Dr. Templeton’s non-viral therapeutics in clinical trials for the treatment of lung, breast, head and neck, and pancreatic cancers, as well as Hepatitis B and C. She continues to work at the forefront of research in gene and cell therapies. Her contributions, as well as those contained in this volume, are sure to advance the state of the art of these revolutionary life-saving technologies.
Book Synopsis The Biotech Business Handbook by : Michael G. Pappas
Download or read book The Biotech Business Handbook written by Michael G. Pappas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: One comment often repeated to me by coworkers in the biotechnology industry deals with their frustration at not understanding how their particular roles fit into their company's overall scheme for developing, manufacturing, and marketing biomedical products. Although these workers know their fields of specialty and responsibilities very well, whether it be in product research and development, regulatory affairs, manufacturing, packaging, quality control, or marketing and sales, they for the most part lack an understanding of precisely how their own contributory pieces fit into the overall scheme of the corporate biotechnology puzzle. The Biotech Business Handbook was written to assist the biotechnologist-whether a tech nician, senior scientist, manager, marketing representative, or college student interested in entering the field-in building a practical knowledge base of the rapidly expanding and maturing biotechnology segment of the healthcare industry. Because biotechnology in the United States and abroad covers many disciplines, much of the information presented in this book deals with the biomedical diagnostic aspects of the industry. Business subjects for the most part unfamiliar to technically oriented people, such as the types of biotechnology corpo rations, their business and corporate structures, their financing, patent, and trademark mat ters, their special legal issues, and the contributions of their consultants are treated in a manner designed to make them clear and understandable.
Book Synopsis Medical Biotechnology by : Pravin Chandra Trivedi
Download or read book Medical Biotechnology written by Pravin Chandra Trivedi and published by . This book was released on 2008-01-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology Has Proved A Boon For Medical Science In Several Ways. Be It In Enhancing Immunity Against Diseases, Or In Providing Genetically Improved Treatment For Ailments, Biotechnology Has Become An Inseparable Part Of The Medical World. Medical Biotechnology Applications Include Gene Therapy, Development Of Vaccines, Skin Grafting, Dna Fingerprinting, Gene Profiling, Pharmacogenomics, Pre-Natal Diagnosis Of Inherited Diseases, Biophrmaceuticals (Insulin, Somatostatin, Interferons), Fertility Control And Stem Cells And Their Applications. The Present Book Medical Biotechnology Incorporates Reviews And Research Articles On Varied Aspects Of Medical Biotechnology. This Book Contains 14 Chapters Incorporating Recent Development In The Subject. Detailed Information Is Given On The Topics Stem Cells: A Gift For Life; Cryopreservation Of Mammalian Cells : A Boon To Biotechnology; Bioartificial Organs Of The Future; Cancer, Phytocompounds And Plant Tissue Culture; Human Genome Sequence: Scope For Genomic Analysis Using Bioinformatics Approaches. Other Articles Includes-Mitochondrial Dysfunction In Human; Emerging Trends In Assisted Reproductive Technology And Their Outcomes; Non-Tuberculous Mycobacteria And Recent Biotechnological Advances In Immunoathogenesis And Treatment Of Rheumatoid Arthritis. Book Cover Articles On Dna Microarray: Basic Technology And Application In Medical Research; Protein Sequence Analysis And Characterization Using Insilico Methods; Gnome Analysis For Drug Designing And Biotechnology & Ipr. Article On Biotechnology Of Extremophiles: Haloarchae Have Added Value To The Book. This Book Will Be Useful To Researchers, Teachers And Students Of Biotechnology, Medical Science, Microbiology, Botany, Zoology And For The Biotechnology Industry People At Large.
Book Synopsis Gene and Cell Therapies by : Eve Hanna
Download or read book Gene and Cell Therapies written by Eve Hanna and published by CRC Press. This book was released on 2020-05-19 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major advances in the field of biotechnology and molecular biology in the twenty-first century have led to a better understanding of the pathophysiology of diseases. A new generation of biopharmaceuticals has emerged, including a wide and heterogeneous range of innovative cell and gene therapies. These therapies aim to prevent or treat chronic and serious life-threatening diseases, previously considered incurable. This book describes the evolution and adaptation of the regulatory environment to assess these therapies in contrast with the resistance of health technology assessment (HTA) agencies and payers to acknowledge the specificity of cell and gene therapies and the need to adapt existing decision-making frameworks. This book provides insights on the learnings from the experience of current cell and gene therapies (regulatory approval, HTA, and market access), in addition to future trends to enhance patient access to these therapies. Key Features: Describes the potential change of treatment paradigm and the specificity of cell and gene therapies, including the gradual move from repeated treatment administration to one-time single administration with the potential to be definite cure Highlights the challenges at the HTA level Discusses the affordability of future cell and gene therapies and the possible challenges for health insurance systems Provides potential solutions to address these challenges and ensure patient access to innovation while maintaining the sustainability of healthcare systems
Download or read book Gene Therapy written by Robert E. Sobol and published by Springer. This book was released on 2013-10-03 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of preclinical and clinical reports on the appli cation of gene therapy to human disease. The focus of these studies is on cancer and cardiovascular disease. There are two fundamental technologies for delivering therapeutic genes to diseased ceHs: either viral vectors, as discussed by Dr. Bal main, or non-viral vector systems, as discussed by Dr. Felgner. The strengths and limitations of each of these delivery systems are charac terized. The use of a therapeutic gene to treat a disease has taken two general approaches. The first is to introduce anormal (i. e. , wild type) gene into the patient that will restore normal gene function. Dr. Weiss man has characterized the tumor suppressor gene (pS3), and has shown that it can restore normal ceH function in cancer cells. The second ap proach is to treat the disease with antisense molecules. Abnormal gene expression can be down-regulated and selectively inhibited by anti sense molecules, which can reverse the pathologie process in cancer cells. Dr. Gewirtz has demonstrated this with anti sense genes on leuke mia, while Dr. Scanlon has applied this principle using ribozymes in human carcinomas. During this symposium, Dr. Engler described clinical studies of gene therapy using growth factors to stimulate new blood vessels in patients with cardiovascular disease. Several gene therapy strategies were used for cancer: overcoming drug resistance by Dr. Bertino, a pro-drug strategy with ganciclovir by Dr.
