Bioactive Natural Products In Drug Discovery

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Bioactive Natural products in Drug Discovery

Author : Joginder Singh
Publisher : Springer Nature
ISBN 13 : 9811513945
Total Pages : 733 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Bioactive Natural products in Drug Discovery by : Joginder Singh

Download or read book Bioactive Natural products in Drug Discovery written by Joginder Singh and published by Springer Nature. This book was released on 2020-04-30 with total page 733 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : World Scientific
ISBN 13 : 9814335371
Total Pages : 695 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Bioactive Natural Products by : Goutam Brahmachari

Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by World Scientific. This book was released on 2012 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Bioactive Natural Products for Pharmaceutical Applications

Author : Dilipkumar Pal
Publisher : Springer Nature
ISBN 13 : 3030540278
Total Pages : 862 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Bioactive Natural Products for Pharmaceutical Applications by : Dilipkumar Pal

Download or read book Bioactive Natural Products for Pharmaceutical Applications written by Dilipkumar Pal and published by Springer Nature. This book was released on 2020-12-14 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the recent innovations relating to various bioactive natural products (such as alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, volatile oils, fixed oils, fats and waxes, proteins and peptides, vitamins, marine products, camptothecin, piperines, carvacrol, gedunin, GABA, ginsenosides) and their applications in the pharmaceutical fields related to academic, research and industry.

Bioactive Compounds from Natural Sources, Second Edition

Author : Corrado Tringali
Publisher : CRC Press
ISBN 13 : 1439822298
Total Pages : 650 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bioactive Compounds from Natural Sources, Second Edition by : Corrado Tringali

Download or read book Bioactive Compounds from Natural Sources, Second Edition written by Corrado Tringali and published by CRC Press. This book was released on 2011-09-27 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.

Drug Discovery from Natural Products

Author : Olga Genilloud
Publisher : Royal Society of Chemistry
ISBN 13 : 1849733619
Total Pages : 435 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Drug Discovery from Natural Products by : Olga Genilloud

Download or read book Drug Discovery from Natural Products written by Olga Genilloud and published by Royal Society of Chemistry. This book was released on 2012 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated review of the most recent trends in natural products, drug discovery, and key lead candidates that are outstanding for their chemistry and biology in novel drug development.

Natural Compounds as Drugs, Volume I

Author : Frank Petersen
Publisher : Springer Science & Business Media
ISBN 13 : 3764381175
Total Pages : 372 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Natural Compounds as Drugs, Volume I by : Frank Petersen

Download or read book Natural Compounds as Drugs, Volume I written by Frank Petersen and published by Springer Science & Business Media. This book was released on 2007-12-27 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a real tour de force of pharmacological literature, this edited volume’s chapters highlight the biodiversity-driven approaches which are now of eminent importance in natural products research. It addresses the question why natural products display such complex chemical information, what makes them unique, as they often are, and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.

Natural Products and Drug Discovery

Author : Pinarosa Avato
Publisher : MDPI
ISBN 13 : 303928746X
Total Pages : 392 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Natural Products and Drug Discovery by : Pinarosa Avato

Download or read book Natural Products and Drug Discovery written by Pinarosa Avato and published by MDPI. This book was released on 2020-04-22 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products hold a prominent position in the current discovery and development of drugs and have diverse indications for both human and animal health. Plants, in particular, play a leading role as a source of specialized metabolites with medical effects. Other organisms, such as marine and terrestrial animals and microorganisms, produce very important drug candidate molecules. Specialized metabolites from these varied natural sources can be used directly as bioactive compounds or drug precursors. In addition, due to their broad chemical diversity, they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites that have been developed into useful medical drug are cardiotonic digoxin from Digitalis sp., antimalarial artemisinin from Artemisia annua, anti-cancer taxol from Taxus sp., or podophyllotoxin from Podophyllum peltatum, which served as a synthetic model for the anti-cancer etoposide. The study of natural products is still attracting great scientific attention and their current importance, as a valuable lead for drug discovery, is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that give the readers of Molecules **MOLECULES NEEDS TO BE ITALICIZED** updated and new perspectives on natural products in drug discovery, including but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays.

Studies in Natural Products Chemistry

Author : Atta-ur- Rahman
Publisher : Elsevier
ISBN 13 : 0444595155
Total Pages : 438 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Studies in Natural Products Chemistry by : Atta-ur- Rahman

Download or read book Studies in Natural Products Chemistry written by Atta-ur- Rahman and published by Elsevier. This book was released on 2012-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry

Medicinal Chemistry of Bioactive Natural Products

Author : Xiao-Tian Liang
Publisher : John Wiley & Sons
ISBN 13 : 0471739332
Total Pages : 482 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Medicinal Chemistry of Bioactive Natural Products by : Xiao-Tian Liang

Download or read book Medicinal Chemistry of Bioactive Natural Products written by Xiao-Tian Liang and published by John Wiley & Sons. This book was released on 2006-03-17 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current discoveries and research into bioactive natural products Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current research and to importance as clinicially useful agents. Rather than attempting to be a comprehensive encyclopedia of bioactive natural products, Medicinal Chemistry of Bioactive Natural Products guides the reader to the key developments in the field. By providing not only practical detail but a historical perspective on the chemistry and biology of the compounds under consideration, the book serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research. Enhanced by examples with updated research results, the discussion covers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and its analogs * The antimalarial properties of the traditional Chinese medicine, Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer's disease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIV agents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and their structurally modified mimics

Natural Bioactive Compounds

Author : Rajeshwar P. Sinha
Publisher : Academic Press
ISBN 13 : 0128206594
Total Pages : 502 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Natural Bioactive Compounds by : Rajeshwar P. Sinha

Download or read book Natural Bioactive Compounds written by Rajeshwar P. Sinha and published by Academic Press. This book was released on 2020-10-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)

The Role of Natural Products in Drug Discovery

Author : J. Mulzer
Publisher : Springer Science & Business Media
ISBN 13 : 3662040425
Total Pages : 363 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis The Role of Natural Products in Drug Discovery by : J. Mulzer

Download or read book The Role of Natural Products in Drug Discovery written by J. Mulzer and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : John Wiley & Sons
ISBN 13 : 3527337946
Total Pages : 544 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Bioactive Natural Products by : Goutam Brahmachari

Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by John Wiley & Sons. This book was released on 2015-03-23 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Drug Discovery and Development

Author : Ramarao Poduri
Publisher : Springer Nature
ISBN 13 : 9811555346
Total Pages : 522 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Drug Discovery and Development by : Ramarao Poduri

Download or read book Drug Discovery and Development written by Ramarao Poduri and published by Springer Nature. This book was released on 2021-02-15 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

Bioactive Natural Products in Drug Discovery

Author :
Publisher :
ISBN 13 : 9789811513954
Total Pages : pages
Book Rating : 4.5/5 (139 download)

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Book Synopsis Bioactive Natural Products in Drug Discovery by :

Download or read book Bioactive Natural Products in Drug Discovery written by and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the books closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the books goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Bioactive Marine Natural Products

Author : Dewan S. Bhakuni
Publisher : Springer Science & Business Media
ISBN 13 : 1402034849
Total Pages : 382 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Bioactive Marine Natural Products by : Dewan S. Bhakuni

Download or read book Bioactive Marine Natural Products written by Dewan S. Bhakuni and published by Springer Science & Business Media. This book was released on 2006-06-30 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R and D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Author : Goutam Brahmachari
Publisher : CRC Press
ISBN 13 : 1439891672
Total Pages : 586 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds by : Goutam Brahmachari

Download or read book Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds written by Goutam Brahmachari and published by CRC Press. This book was released on 2013-02-20 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure–activity relationships.

Plant Bioactives and Drug Discovery

Author : Valdir Cechinel-Filho
Publisher : John Wiley & Sons
ISBN 13 : 1118259920
Total Pages : 600 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Plant Bioactives and Drug Discovery by : Valdir Cechinel-Filho

Download or read book Plant Bioactives and Drug Discovery written by Valdir Cechinel-Filho and published by John Wiley & Sons. This book was released on 2012-04-11 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.