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Behavioral And Neural Genetics Of Zebrafish
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Book Synopsis Behavioral and Neural Genetics of Zebrafish by : Robert T. Gerlai
Download or read book Behavioral and Neural Genetics of Zebrafish written by Robert T. Gerlai and published by Academic Press. This book was released on 2020-04-03 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics
Book Synopsis Methods of Behavior Analysis in Neuroscience by : Jerry J. Buccafusco
Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Book Synopsis Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by : Robert T. Gerlai
Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts
Book Synopsis The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish by : Allan V. Kalueff
Download or read book The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish written by Allan V. Kalueff and published by Springer. This book was released on 2017-02-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book “The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling” explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.
Book Synopsis The world according to zebrafish: How neural circuits generate behaviour by : Gonzalo G. De Polavieja
Download or read book The world according to zebrafish: How neural circuits generate behaviour written by Gonzalo G. De Polavieja and published by Frontiers E-books. This book was released on 2014-11-07 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.
Book Synopsis Genetic Dissection of Neural Circuits and Behavior by : Stephen F. Goodwin
Download or read book Genetic Dissection of Neural Circuits and Behavior written by Stephen F. Goodwin and published by . This book was released on 2009 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest volume in the widely-praised Advances in Genetics series.
Book Synopsis Behavioral Neurogenetics by : John F. Cryan
Download or read book Behavioral Neurogenetics written by John F. Cryan and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental disorders. The importance of gene-environment interactions is emphasised and the role of neuroimaging in unravelling the functional consequences of genetic variability described. This volume will be valued by both the basic scientist and clinician alike who may use it as a detailed reference book. It will also be of use to the novice to the field, to whom it will serve as an in-depth introduction to this exciting area of research.
Book Synopsis Zebrafish Models in Neurobehavioral Research by : Allan V. Kalueff
Download or read book Zebrafish Models in Neurobehavioral Research written by Allan V. Kalueff and published by Humana Press. This book was released on 2010-10-28 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal models have traditionally played a crucial role in improving our understanding of brain pathogenesis. Zebrafish (Danio rerio) have generated considerable discoveries in the areas of genetics, embryology, endocrinology, and neuroscience. Zebrafish Models in Neurobehavioral Research emphasizes the growing importance of zebrafish in neurobehavioral research and portrays an extensive, thorough perspective on the emergence of zebrafish as robust and translational models. Written by leading international experts, the book covers major topics ranging from stress to learned recognition of environment, encompassing a wide spectrum of the utility of zebrafish within neurobiological disciplines. The chapters provide authoritative reviews of many zebrafish paradigms commonly used in the field today. This book will be a useful guide for zebrafish researchers, and will complement another related book from the popular Neuromethods series, Zebrafish Neurobehavioral Protocols. Comprehensive and up-to-date, Zebrafish Models in Neurobehavioral Research serves as an ideal resource for scientists new to the field as well as for established researchers seeking valuable insight into the growing utility of zebrafish in neuroscience.
Book Synopsis Neuroanatomy of the Zebrafish Brain by : Mario F. Wulliman
Download or read book Neuroanatomy of the Zebrafish Brain written by Mario F. Wulliman and published by Birkhäuser. This book was released on 2012-12-06 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fish Development and Genetics by : Gong Zhiyuan
Download or read book Fish Development and Genetics written by Gong Zhiyuan and published by World Scientific. This book was released on 2004-11-02 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: The zebrafish is the most important fish model in developmental and genetic analyses. This book contains 19 review articles covering a broad spectrum of topics, from development to genetic tools. The contents range from early development, the role of maternal factors and gastrulation, to tissue differentiation and organogenesis, such as development of the organizer, notochord, floor plate, nervous system, somites, muscle, skeleton and endoderm. The genetic tools cover morpholino knock-down, transgenics, fish cloning, transposons and genome evolution. The book also includes two chapters on genome mapping and embryonic stem cells in medaka, another important model fish. Summarizing the state-of-the-art studies of the zebrafish model and focusing on the molecular aspects of development, this book is a valuable reference for students learning the basic aspects of the zebrafish model, and for researchers seeking resources in zebrafish research. Contents:The Role of Maternal Factors in Early Zebrafish Development (F Pelegri)Gastrulation in Zebrafish (F Ulrich & C-P Heisenberg)Development of the Zebrafish Organiser and Notochord (K A Thomas & D L Stemple)Formation and Functions of the Floor Plate (J Tian & K Sampath)Form and Function in the Zebrafish Nervous System (M Hendricks & S Jesuthasan)Development of the Primary Nervous System of the Zebrafish Embryo (U Strähle & V Korzh)Making Scents: Development and Function of the Olfactory Sensory System (K E Whitlock)Somites Segmentation: A View from Fish (H Takeda & Y Saga)Vertebrate Somite Development, Notch Signaling and Others (Y-J Jiang)Molecular Regulation of Fish Muscle Development and Growth (S J Du)Skeletogenesis in Zebrafish Danio rerio: Evolutionary and Developmental Aspects (S Fisher & P M Mabee)Endoderm Formation in Zebrafish (N B David et al.)Gene 'Knockdown' Approaches Using Unconventional Antisense Oligonucleotides (E Chen et al.)Transgenic Fish for Developmental Biology Studies (Z-Y Gong et al.)Cloning the Zebrafish (B Ju et al.)Applications of Transponsable Elements in Fish for Transgenesis and Functional Genomics (P B Hacketts et al.)Evolution of the Zebrafish Genome (J H Postlethwait)Medaka Genome Mappling for Functional Genomics (H Mitani et al.)Medaka Embryonic Stem Cells (Y-H Hong & M Schartl) Readership: Upper level undergraduates, graduate students, academics and researchers in cell & molecular biology, fish & marine biology and genetics. Keywords:Zebrafish;Medaka;Embrynonic Development;Axial Structures;Neurogenesis;Somites;Transgenics;GenomeKey Features:Contributed by active researchers working in the field of developmental biology of the zebrafish and medakaCovers essentially all major topics from early development to organogenesis as well as several most important genetic toolsRepresents most updated reviews in selected areas of the rapidly developing field
Book Synopsis Zebrafish Neurobehavioral Protocols by : Allan V. Kalueff
Download or read book Zebrafish Neurobehavioral Protocols written by Allan V. Kalueff and published by Humana Press. This book was released on 2011-04-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a model organism, zebrafish (Danio rerio) offer an opportunity to perform steadfast scientific investigations in a robust and high-throughput manner. In Zebrafish Neurobehavioral Protocols, experts in the field provide a series of detailed behavioral protocols dealing with the major current research areas in the field of behavioral neuroscience. The chapters discuss the use and interpretation of video-aided quantification of zebrafish behaviors, describe novel assays commonly used to quantify emotionality, learning, memory, and social behaviors in zebrafish, and instruct how to quantify endocrine responses and correlate them with behavior. Written in the Neuromethods series format, the chapters provide authoritative reviews of many commonly used approaches in the field today. This "how to" book will be a useful practical guide for zebrafish researchers and will complement another related book from this series, Zebrafish Models in Neurobehavioral Research. Cutting-edge and timely, Zebrafish Neurobehavioral Protocols serves as an excellent compilation epitomizing the growing potential of zebrafish in modern scientific inquiry.
Book Synopsis Zebrafish Protocols for Neurobehavioral Research by : Allan V. Kalueff
Download or read book Zebrafish Protocols for Neurobehavioral Research written by Allan V. Kalueff and published by Humana Press. This book was released on 2012-06-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.
Book Synopsis Sourcebook of Models for Biomedical Research by : P. Michael Conn
Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008-03-07 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.
Download or read book Zebrafish written by James F. Amatruda and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated edition introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Zebrafish: Methods and Protocols, Third Edition serves as an invaluable guide to propel advances in developmental biology, disease modeling, and regeneration research using zebrafish and medaka as model systems.
Book Synopsis Zebrafish by : Christiane Nusslein-Volhard
Download or read book Zebrafish written by Christiane Nusslein-Volhard and published by Oxford University Press. This book was released on 2002-09-19 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The zebrafish has become one of the most important model organisms to study biological processes within a living body. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiology and disease. This book not only provides a complete set of instructions that will allow researchers to establish the zebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.
Book Synopsis Laboratory Fish in Biomedical Research by : Livia D'Angelo
Download or read book Laboratory Fish in Biomedical Research written by Livia D'Angelo and published by Academic Press. This book was released on 2021-08-28 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fish, and particularly zebrafish, have become the fastest-growing segment of the research population. They offer several advantages, in terms of biology and technologies to apply, and thus are employed in numerous research fields. Laboratory Fish in Biomedical Research: Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Swordtail Fish, Cavefish, Stickleback, Goldfish and Danionella Translucida addresses the relevant and increasing need to collect cutting-edge knowledge on husbandry, maintenance, welfare and experimental protocols of the most common freshwater species under standard laboratory conditions. Provides husbandry and management protocols, devices and water systems Shows strength and weakness of breeding Explores potential scientific applications and experimental protocols. with regards to the most used freshwater fish used for scientific purposes
Book Synopsis Development and Engineering of Dopamine Neurons by : Jeroen Pasterkamp
Download or read book Development and Engineering of Dopamine Neurons written by Jeroen Pasterkamp and published by Springer Science & Business Media. This book was released on 2009-12-16 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.
