Bacterial Protein Toxins V2A

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Publisher : Elsevier
ISBN 13 : 0323150519
Total Pages : 432 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Bacterial Protein Toxins V2A by : Solomon Kadis

Download or read book Bacterial Protein Toxins V2A written by Solomon Kadis and published by Elsevier. This book was released on 2012-12-02 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Toxins, A Comprehensive Treatise, Volume IIA: Bacterial Protein Toxins provides a comprehensive discussion of various aspects of bacterial toxins. The book's 10 chapters discuss the following: botulinum toxin; tetanus toxin; Clostridium perfringens toxins types A, B, C, D, and E; cholera toxins; the exotoxin of Shigella dysenteriae; protein toxins from Bordetella pertussis; Salmonella typhimurium and Escherichia coli neurotoxins; toxins of Proteus mirabilis; and Listeria monocytogenes toxin. Each chapter covers the nature of the toxin, toxin production and purification, and mode of action.

Bacterial Protein Toxins

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662059711
Total Pages : 713 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Bacterial Protein Toxins by : K. Aktories

Download or read book Bacterial Protein Toxins written by K. Aktories and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.

The Comprehensive Sourcebook of Bacterial Protein Toxins

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Author :
Publisher : Academic Press
ISBN 13 : 0128005890
Total Pages : 1200 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Comprehensive Sourcebook of Bacterial Protein Toxins by : Joseph E. Alouf

Download or read book The Comprehensive Sourcebook of Bacterial Protein Toxins written by Joseph E. Alouf and published by Academic Press. This book was released on 2015-05-29 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Comprehensive Sourcebook of Bacterial Protein Toxins 4th Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them. Focused chapters on toxin applications and common properties or general features of toxins.

Bacterial Protein Toxins

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9781139443593
Total Pages : 268 pages
Book Rating : 4.4/5 (435 download)

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Book Synopsis Bacterial Protein Toxins by : Alistair J. Lax

Download or read book Bacterial Protein Toxins written by Alistair J. Lax and published by Cambridge University Press. This book was released on 2011-04-28 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context.

Bacterial Protein Toxins

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Author :
Publisher : Elsevier
ISBN 13 : 032316322X
Total Pages : 568 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Bacterial Protein Toxins by : Thomas C. Montie

Download or read book Bacterial Protein Toxins written by Thomas C. Montie and published by Elsevier. This book was released on 2013-09-11 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Protein Toxins V3

The Comprehensive Sourcebook of Bacterial Protein Toxins

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Author :
Publisher : Elsevier
ISBN 13 : 9780128001882
Total Pages : 0 pages
Book Rating : 4.0/5 (18 download)

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Book Synopsis The Comprehensive Sourcebook of Bacterial Protein Toxins by : Joseph E. Alouf

Download or read book The Comprehensive Sourcebook of Bacterial Protein Toxins written by Joseph E. Alouf and published by Elsevier. This book was released on 2015-06-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content.

Bacterial Toxins

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527614605
Total Pages : 334 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bacterial Toxins by : Klaus Aktories

Download or read book Bacterial Toxins written by Klaus Aktories and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance. A solid introduction to toxin structure and functions, as well as a valuable source of methodology for researchers in molecular biology, pharmacology and experimental medicine.

Bacterial Toxins

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592590527
Total Pages : 378 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Bacterial Toxins by : Otto Holst

Download or read book Bacterial Toxins written by Otto Holst and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interest of investigators across a broad spectrum of scientific dis- plines has been steadily stimulated by the field of bacterial toxin research, an area that makes use of a large variety of biological, chemical, physicochemical, and medically oriented approaches. Researchers studying bacterial toxins need to be acquainted with all these disciplines in order to work effectively in the field. To date, there has been no published collection offering detailed descr- tions of the techniques and methods needed by researchers operating across the field’sdiverse areas. The present volume Bacterial Toxins: Methods and Pro- cols, is intended to fill this gap. Bacterial Toxins: Methods and Protocols consists of two sections: one on protein toxins (15 chapters) and one on endotoxins (5 chapters). Each s- tion is introduced by an overview article (Chapters 1 and 16). The protocols collected represent state-of-the-art techniques that each have high impact on future bacterial toxin research. All methods are described by authors who have regularly been using the protocol in their own laboratories. Included in each chapter is a brief introduction to the method being described.

Sourcebook of Bacterial Protein Toxins

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Publisher :
ISBN 13 :
Total Pages : 540 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Sourcebook of Bacterial Protein Toxins by : Joseph E. Alouf

Download or read book Sourcebook of Bacterial Protein Toxins written by Joseph E. Alouf and published by . This book was released on 1991 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an international team of leading scientists, this volume draws together a wealth of information on the structure, regulation, and activity of bacterial protein toxins. A comprehensive sourcebook on bacterial toxins, Sourcebook of Bacterial Protein Toxins is the first book designed to draw together current knowledge on these toxins. The 22 chapters of this book have been written by 44 internationally known specialists who have significantly contributed to the progress in the domains covered. This book will appeal to a wide readership, including microbiologists, biochemists, cell biologists, and physicians. It will also arouse the interest of students and scientists in other disciplines who see the power of these fascinating biological agents, either as exquisitely specific probes of cellular processes or as extremely potent agents of infectious disease.

Microbial Protein Toxins

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540235620
Total Pages : 264 pages
Book Rating : 4.2/5 (356 download)

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Book Synopsis Microbial Protein Toxins by : Manfred Schmitt

Download or read book Microbial Protein Toxins written by Manfred Schmitt and published by Springer Science & Business Media. This book was released on 2004-12-10 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.

The Comprehensive Sourcebook of Bacterial Protein Toxins

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Author :
Publisher :
ISBN 13 :
Total Pages : 750 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Comprehensive Sourcebook of Bacterial Protein Toxins by : John H. Freer

Download or read book The Comprehensive Sourcebook of Bacterial Protein Toxins written by John H. Freer and published by . This book was released on 1999 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the First Edition, with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field.

Guidebook to Protein Toxins and Their Use in Cell Biology

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Author :
Publisher : OUP Oxford
ISBN 13 : 019154728X
Total Pages : 278 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Guidebook to Protein Toxins and Their Use in Cell Biology by : Rino Rappuoli

Download or read book Guidebook to Protein Toxins and Their Use in Cell Biology written by Rino Rappuoli and published by OUP Oxford. This book was released on 1997-05-29 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of complexity, from the formic acid provided by ants to bacterial proteins composed of thousands of amino acids. This Guidebook considers the more complex protein and peptide toxins and groups them according to their mode of action. Topics covered include: membrane-permeabilizing toxins; toxins affecting signal transduction and protein synthesis; cytoskeleton-affecting toxins; toxins affecting the immune and inflammatory response. This class of biomolecules will be of interest to a wide range of researchers in cell biology, neuroscience, and toxicology.

Uptake and Trafficking of Protein Toxins

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Publisher : Springer
ISBN 13 : 3319588931
Total Pages : 256 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Uptake and Trafficking of Protein Toxins by : Holger Barth

Download or read book Uptake and Trafficking of Protein Toxins written by Holger Barth and published by Springer. This book was released on 2017-12-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary clostridial enterotoxins, anthrax toxins and diphtheria toxin. In brief, specific binding/transport (B) subunits deliver the enzyme (A) subunits into the cytosol, where the latter modify their substrates, producing cytotoxic effects and the characteristic toxin-associated diseases. Key mechanisms for the transport of the A subunits from endosomes into the cytosol and the role of trans-membrane pores formed by the B subunits and host cell chaperones for this process are reviewed. The book’s closing chapters focus on compounds which inhibit the transport of the A subunits from endosomes into the cytosol and therefore might lead to novel therapeutic strategies for toxin-associated diseases. These substances include pharmacological inhibitors of the host cell chaperones involved, as well as multivalent and heterocyclic molecules that specifically block the toxins’ translocation channels. This volume offers an up-to-date resource for scientists.

Pore-Forming Toxins

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Publisher : Springer Science & Business Media
ISBN 13 : 3642565085
Total Pages : 168 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Pore-Forming Toxins by : Gisou van der Goot

Download or read book Pore-Forming Toxins written by Gisou van der Goot and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pore-forming toxins are virulence factors produced by a great variety of pathogenic bacteria ranging from the Gram-positive Staphylococcus aureus to the Gram-negative Helicobacter pylory. The recent studies reviewed in this volume describe the progress that has been made in dissecting the different steps of the mode of action of these proteins which generally include binding to specific cell surface receptors, oligomerization into ring like structures and membrane perforation.

Bacterial Protein Toxins

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Book Synopsis Bacterial Protein Toxins by : Samuel J. Ajl

Download or read book Bacterial Protein Toxins written by Samuel J. Ajl and published by . This book was released on 1970 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial Protein Toxins

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Author :
Publisher :
ISBN 13 : 9780511121180
Total Pages : 239 pages
Book Rating : 4.1/5 (211 download)

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Book Synopsis Bacterial Protein Toxins by : Alistair J. Lax

Download or read book Bacterial Protein Toxins written by Alistair J. Lax and published by . This book was released on 2005 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial toxins are potent molecular poisons that are released by bacteria to cause disease. This book describes how toxins can enter cells to subvert cell function by interfering with the key processes involved in cell growth and division, and the ability of cells to differentiate into specialised cells.

Bacterial Protein Toxins

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Publisher :
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Bacterial Protein Toxins by : F. J. Fehrenbach

Download or read book Bacterial Protein Toxins written by F. J. Fehrenbach and published by . This book was released on 1988 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: