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Author : Jun Ren
Publisher :
ISBN 13 :
Total Pages : 199 pages
Book Rating : 4.:/5 (93 download)
Download or read book Autophagy and Protein Quality Control in Cardiometabolic Diseases written by Jun Ren and published by . This book was released on 2015 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jun Ren
Publisher : Academic Press
ISBN 13 : 0128054425
Total Pages : 342 pages
Book Rating : 4.1/5 (28 download)
Download or read book Autophagy and Cardiometabolic Diseases written by Jun Ren and published by Academic Press. This book was released on 2018-04-12 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners. Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases Provides knowledge from internationally recognized contributors in the field Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases Contains access to a companion website with additional illustrations
Author : H. Böhles
Publisher : CRC Press
ISBN 13 : 9783887631048
Total Pages : 188 pages
Book Rating : 4.6/5 (31 download)
Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.
Author : Jun Ren
Publisher : Frontiers Media SA
ISBN 13 : 2889715833
Total Pages : 310 pages
Book Rating : 4.8/5 (897 download)
Download or read book New Drug Targets for Proteotoxicity in Cardiometabolic Diseases written by Jun Ren and published by Frontiers Media SA. This book was released on 2021-11-02 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : José Marín-García
Publisher : Springer Science & Business Media
ISBN 13 : 0387255745
Total Pages : 415 pages
Book Rating : 4.3/5 (872 download)
Download or read book Mitochondria and the Heart written by José Marín-García and published by Springer Science & Business Media. This book was released on 2005-05-05 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex network of cellular interactions, involving (1) generation and detoxification of reactive oxygen species, including superoxide anion, hy-drogen peroxide, and hydroxyl radical; (2) maintenance of the antioxidant glutathione in a reduced state and adequate level of mitochondrial matrix superoxide dismutase; (3) cytoplasmic calcium homeostasis, particularly under conditions of cellular calcium loading; (4) transport of metabolites between cytoplasm and matrix; (5) both programmed (apoptosis) and necrotic cell death; and (6) cell growth and development. It is therefore not surprising that this organelle has come to be the center stage in many current investigations of cardiovascular diseases, aging, and agi- related disease. Concomitant with these advances, an impressive effort is under- way for the development of new tools and methodologies to study mitochondrial structure and function, including powerful ways to visualize, monitor, and alter the organelle function to assess the genetic consequences of these perturbations.
Author : Xuejun Wang
Publisher : Frontiers Media SA
ISBN 13 : 2889668061
Total Pages : 175 pages
Book Rating : 4.8/5 (896 download)
Download or read book Targeting Cardiac Proteotoxicity written by Xuejun Wang and published by Frontiers Media SA. This book was released on 2021-05-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas Pulinilkunnil
Publisher : Frontiers Media SA
ISBN 13 : 2889459381
Total Pages : 89 pages
Book Rating : 4.8/5 (894 download)
Download or read book Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease written by Thomas Pulinilkunnil and published by Frontiers Media SA. This book was released on 2019-08-08 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Alaeddin Abukabda
Publisher : BoD – Books on Demand
ISBN 13 : 1838819495
Total Pages : 144 pages
Book Rating : 4.8/5 (388 download)
Download or read book Cardiovascular Risk Factors in Pathology written by Alaeddin Abukabda and published by BoD – Books on Demand. This book was released on 2021-04-21 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad overview of the molecular mechanisms associated with relevant and significant cardiovascular conditions that continue to plague humanity. It also discusses potential and promising therapeutic avenues targeted at addressing these conditions. The overarching goal of this multifaceted work is to entice future and current members of the scientific community to direct their endeavors towards improving our current knowledge of cardiovascular disease conditions and curb their impact on our everyday lives.
Author : VijayaKumar Sukumaran
Publisher : Frontiers Media SA
ISBN 13 : 2889764974
Total Pages : 185 pages
Book Rating : 4.8/5 (897 download)
Download or read book Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM) written by VijayaKumar Sukumaran and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Huabo Su
Publisher : Frontiers Media SA
ISBN 13 : 2889715000
Total Pages : 150 pages
Book Rating : 4.8/5 (897 download)
Download or read book Post-Translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease written by Huabo Su and published by Frontiers Media SA. This book was released on 2021-10-18 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jos A.F. Op den Kamp
Publisher : Springer Science & Business Media
ISBN 13 : 3642731848
Total Pages : 474 pages
Book Rating : 4.6/5 (427 download)
Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.
Author : Sebastiano Sciarretta
Publisher : Frontiers Media SA
ISBN 13 : 2889665569
Total Pages : 111 pages
Book Rating : 4.8/5 (896 download)
Download or read book Mitochondrial Dysfunction and Cardiovascular Diseases written by Sebastiano Sciarretta and published by Frontiers Media SA. This book was released on 2021-03-04 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yaming Jiu
Publisher : Frontiers Media SA
ISBN 13 : 2832510469
Total Pages : 176 pages
Book Rating : 4.8/5 (325 download)
Download or read book Intermediate filaments structure, function and clinical significance written by Yaming Jiu and published by Frontiers Media SA. This book was released on 2023-01-02 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gaetano Santulli
Publisher : Springer
ISBN 13 : 3319553305
Total Pages : 644 pages
Book Rating : 4.3/5 (195 download)
Download or read book Mitochondrial Dynamics in Cardiovascular Medicine written by Gaetano Santulli and published by Springer. This book was released on 2017-05-25 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. Thus, it will assist scientists and clinicians alike in furthering basic and translational research. Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders.
Author : Monte Willis
Publisher : Academic Press
ISBN 13 : 0124055257
Total Pages : 339 pages
Book Rating : 4.1/5 (24 download)
Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. - Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research - Gives concise explanations of key issues and background reading suggestions - Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology
Author : Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
ISBN 13 : 3642307256
Total Pages : 599 pages
Book Rating : 4.6/5 (423 download)
Download or read book Sex and Gender Differences in Pharmacology written by Vera Regitz-Zagrosek and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: A trailblazing assessment of sex and gender differences in reactions to drug therapy, this volume reflects the topic’s growing recognition. Analyses by international experts on both pharmacokinetics and drug development are informed by an extensive data set.
Author : Soo-Kyoung Choi
Publisher : Frontiers Media SA
ISBN 13 : 283251426X
Total Pages : 145 pages
Book Rating : 4.8/5 (325 download)
Download or read book Diabetes, hypertension and cardiovascular diseases, volume II written by Soo-Kyoung Choi and published by Frontiers Media SA. This book was released on 2023-02-10 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:
