Alcohol, Drugs, Genes and the Clinical Laboratory

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Author :
Publisher : Academic Press
ISBN 13 : 012809334X
Total Pages : 236 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Alcohol, Drugs, Genes and the Clinical Laboratory by : Amitava Dasgupta

Download or read book Alcohol, Drugs, Genes and the Clinical Laboratory written by Amitava Dasgupta and published by Academic Press. This book was released on 2016-10-17 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures Provides examples from clinical and everyday situations Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse

Pharmacogenomics of Alcohol and Drugs of Abuse

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Author :
Publisher : CRC Press
ISBN 13 : 1439856117
Total Pages : 255 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Pharmacogenomics of Alcohol and Drugs of Abuse by : Amitava Dasgupta

Download or read book Pharmacogenomics of Alcohol and Drugs of Abuse written by Amitava Dasgupta and published by CRC Press. This book was released on 2012-04-23 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy. Applying these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.

Fighting the Opioid Epidemic

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Publisher : Elsevier
ISBN 13 : 0128223901
Total Pages : 160 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Fighting the Opioid Epidemic by : Amitava Dasgupta

Download or read book Fighting the Opioid Epidemic written by Amitava Dasgupta and published by Elsevier. This book was released on 2020-07-22 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual. Covers all important aspects of opioid abuse, including genetic and environmental factors Discusses pharmacology, toxicology and the pharmacogenomics related to opioid metabolism Presents genetic and environmental factors associated with those vulnerable to opioid addiction, as well as the pitfalls of drug testing in pain management

Critical Issues in Alcohol and Drugs of Abuse Testing

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Publisher : Academic Press
ISBN 13 : 0128156082
Total Pages : 560 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Critical Issues in Alcohol and Drugs of Abuse Testing by : Amitava Dasgupta

Download or read book Critical Issues in Alcohol and Drugs of Abuse Testing written by Amitava Dasgupta and published by Academic Press. This book was released on 2019-01-10 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Alcohol and Its Biomarkers

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Publisher : Elsevier
ISBN 13 : 0128004096
Total Pages : 312 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Alcohol and Its Biomarkers by : Amitava Dasgupta

Download or read book Alcohol and Its Biomarkers written by Amitava Dasgupta and published by Elsevier. This book was released on 2015-02-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods Explains the difference between clinical and forensic alcohol measurement Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking

The Genetics of Alcoholism

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Publisher : Alcohol and Alcoholism
ISBN 13 : 9780195088779
Total Pages : 420 pages
Book Rating : 4.0/5 (887 download)

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Book Synopsis The Genetics of Alcoholism by : Henri Begleiter

Download or read book The Genetics of Alcoholism written by Henri Begleiter and published by Alcohol and Alcoholism. This book was released on 1995 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.

Laboratory Screening and Diagnostic Evaluation

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Publisher : Springer Publishing Company
ISBN 13 : 0826140939
Total Pages : 1111 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Laboratory Screening and Diagnostic Evaluation by : Kelly Small Casler, DNP, APRN, FNP-BC, CHSE

Download or read book Laboratory Screening and Diagnostic Evaluation written by Kelly Small Casler, DNP, APRN, FNP-BC, CHSE and published by Springer Publishing Company. This book was released on 2022-04-25 with total page 1111 pages. Available in PDF, EPUB and Kindle. Book excerpt: "[the authors] did a masterful job of creating and editing this gold standard book that should be used by all clinicians and incorporated into all nursing and health sciences curriculums." -Bernadette Mazurek Melnyk, PhD, APRN-CNP, FNAP, FAANP, FAAN Vice President for Health Promotion University Chief Wellness Officer Dean and Helene Fuld Health Trust Professor of Evidence-Based Practice, College of Nursing Professor of Pediatrics & Psychiatry, College of Medicine Executive Director, the Helene Fuld Health Trust National Institute for EBP The Ohio State University This is the only book to explicitly guide clinicians through an evidence-based approach to ordering and interpreting laboratory tests. With over 160 commonly ordered tests, this book is designed to foster more accurate clinical decision-making to attain the highest level of patient care. This book summarizes more than 3000 pieces of evidence and incorporates clinical expertise and decision-making on the ordering and interpretation of tests. To promote ease of use, a convenient table maps labs and their corresponding chapter numbers to the relevant body system to promote ease of use. Each laboratory test is presented in a consistent format with information on physiology, indications (screening, diagnosis, and monitoring), algorithms, test interpretation and follow-up testing, patient education, and related diagnoses. Additional valuable features include clinical pearls that highlight common pitfalls and gaps in reasoning, and a cost-benefit analysis. This book also includes CPT and ICD-10 codes, charts and tables for clarification, and references for further study. Key Features: Delivers a strong, evidence-based approach to ordering and interpreting over 160 laboratory tests Promotes accurate clinical decision-making toward achieving the Triple Aim Includes abundant clinical pearls highlighting common pitfalls and gaps in reasoning Provides cost-benefit analysis and discussion of laboratory testing within a high-value healthcare culture Includes 175 supplemental case examples and 200 self-assessment questions to facilitate instruction and learning Includes more than 3000 pieces of evidence from interprofessional resources

Human Drug Metabolism

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Publisher : John Wiley & Sons
ISBN 13 : 1119458560
Total Pages : 688 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Human Drug Metabolism by : Michael D. Coleman

Download or read book Human Drug Metabolism written by Michael D. Coleman and published by John Wiley & Sons. This book was released on 2020-02-19 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a timely update to a key textbook on human drug metabolism The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines recent progress and advances in this fast moving field and its clinical impact. Human Drug Metabolism, 3rd Edition begins by covering basic concepts such as clearance and bioavailability, and looks at the evolution of biotransformation, and how drugs fit into this carefully managed biological environment. More information on how cytochrome P450s function and how they are modulated at the sub-cellular level is offered in this new edition. The book also introduces helpful concepts for those struggling with the relationship of pharmacology to physiology, as well as the inhibition of biotransformational activity. Recent advances in knowledge of a number of other metabolizing systems are covered, including glucuronidation and sulphation, along with the main drug transporters. Also, themes from the last edition are developed in an attempt to chart the progress of personalized medicine from concepts towards practical inclusion in routine therapeutics. The last chapter focuses on our understanding of how and why drugs injure us, both in predictable and unpredictable ways. Appendix A highlights some practical approaches employed in both drug metabolism research and drug discovery, whilst Appendix B outlines the metabolism of some drugs of abuse. Appendix C advises on formal examination preparation and Appendix D lists some substrates, inducers and inhibitors of the major human cytochrome P450s. Fully updated to reflect advances in the scientific field of drug metabolism and its clinical impact Reflects refinements in the author's teaching method, particularly with respect to helping students understand biological systems and how they operate Illustrates the growing relationship between drug metabolism and personalized medicine Includes recent developments in drug discovery, genomics, and stem cell technologies Human Drug Metabolism, 3rd Edition is an excellent book for advanced undergraduate and graduate students in molecular biology, biochemistry, pharmacology, pharmacy, and toxicology. It will also appeal to professionals interested in an introduction to this field, or who want to learn more about these bench-to-bedside topics to apply it to their practice.

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder

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Author :
Publisher : American Psychiatric Pub
ISBN 13 : 0890426821
Total Pages : 226 pages
Book Rating : 4.8/5 (94 download)

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Book Synopsis The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder by : American Psychiatric Association

Download or read book The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder written by American Psychiatric Association and published by American Psychiatric Pub. This book was released on 2018-01-11 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The guideline focuses specifically on evidence-based pharmacological treatments for AUD in outpatient settings and includes additional information on assessment and treatment planning, which are an integral part of using pharmacotherapy to treat AUD.

Wilkins' Clinical Practice of the Dental Hygienist

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Publisher : Jones & Bartlett Learning
ISBN 13 : 1284217809
Total Pages : 1191 pages
Book Rating : 4.2/5 (842 download)

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Book Synopsis Wilkins' Clinical Practice of the Dental Hygienist by : Linda D. Boyd

Download or read book Wilkins' Clinical Practice of the Dental Hygienist written by Linda D. Boyd and published by Jones & Bartlett Learning. This book was released on 2020-01-22 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Staying true to Esther Wilkins’ pioneering vision that made her best-selling text the “Bible” for dental hygienists, Wilkins’ Clinical Practice of the Dental Hygienist, Thirteenth Edition progresses through crucial topics in dental hygiene in a straightforward format to ensure students develop the knowledge and skills they need for successful, evidence-based practice in today’s rapidly changing oral health care environment. This cornerstone text, used in almost every dental hygiene education program in the country, has been meticulously updated by previous co-authors, Linda Boyd and Charlotte Wyche, and new co-author Lisa Mallonee to even better meet the needs of today’s students and faculty, while reflecting the current state of practice in dental hygiene. Maintaining the hallmark outline format, the Thirteenth Edition continues to offer the breadth and depth necessary not only for foundation courses but for use throughout the entire dental hygiene curriculum.

Tutorials in Clinical Chemistry

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Publisher : Elsevier
ISBN 13 : 0128229187
Total Pages : 556 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Tutorials in Clinical Chemistry by : Ibrahim A. Hashim

Download or read book Tutorials in Clinical Chemistry written by Ibrahim A. Hashim and published by Elsevier. This book was released on 2023-10-27 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tutorials in Clinical Chemistry is designed for trainee pathology residents, clinical chemists, medical students, and clinical laboratory scientists, in addition to those preparing for board and postgraduate examination. It is helpful to those in training as well as a teaching aid for mentors, faculty, and directors. The book is organized into 17 system-based chapters covering essential pathophysiology, biochemical investigation, and technical aspects of relevance to results interpretation. Tutorials in Clinical Chemistry is a must-have, didactic and essential knowledge as well as practical resource for learning and review. ? Facilitates easy access to troubleshooting common questions within a daily practice ? Provides the landscape for the required knowledge and competency in clinical chemistry ? Presents concise, direct, practical material for clinicians and clinical practitioners reaching out to the clinical laboratory for advice and interpretation of findings ? Covers all aspects of clinical chemistry fellowship curriculum

Fetal Alcohol Spectrum Disorders

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Publisher : Springer Nature
ISBN 13 : 3031323866
Total Pages : 497 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Fetal Alcohol Spectrum Disorders by : Omar A. Abdul-Rahman

Download or read book Fetal Alcohol Spectrum Disorders written by Omar A. Abdul-Rahman and published by Springer Nature. This book was released on 2023-07-19 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fetal alcohol spectrum disorders (FASD) represent a range of physical, mental, and behavioral disabilities caused by alcohol use during pregnancy, or prenatal alcohol exposure (PAE). FASDs are considered to be one of the leading causes of developmental disability, with an estimated 2-5% of children being born with FASD each year in the world. Despite its high prevalence, FASD is often misdiagnosed or underdiagnosed, making intervention more challenging. A multidisciplinary team of providers who understand the diagnostic requirements is crucial for an accurate FASD diagnosis. This text provides a comprehensive, state-of-the art review of this field, and serves as a valuable resource for clinicians and researchers with an interest in FASD. The book provides a detailed overview for clinicians of various backgrounds on the diagnostic process, extensive mechanistic and embryologic data, neuropsychologic aspects of the condition, prevention and treatment approaches, and the ethical, legal, and policy perspectives that impact patients and families. The chapters are organized parallel to the journey of individuals who experience alcohol-related conditions, beginning with the prenatal period addressing epidemiology of alcohol exposure, prevention and interventions, continuing through the fetal experience with a focus on embryology. Challenges of children and their families are considered next including the diagnostic process and health effects. Finally, issues related to systems of care for individuals with FASD and the broader community are addressed. The global context of FASD is presented throughout the textbook. Written by experts in the field, Fetal Alcohol Spectrum Disorders provides a concise yet comprehensive summary of the current status of this issue that helps guide prevention efforts, the diagnostic process, school and community interventions, and global policy efforts.

Seminars in Consultation-Liaison Psychiatry

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Publisher : Cambridge University Press
ISBN 13 : 1911623540
Total Pages : 471 pages
Book Rating : 4.9/5 (116 download)

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Book Synopsis Seminars in Consultation-Liaison Psychiatry by : Rachel Thomasson

Download or read book Seminars in Consultation-Liaison Psychiatry written by Rachel Thomasson and published by Cambridge University Press. This book was released on 2024-01-18 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and practically oriented review of consultation-liaison psychiatry, covering clinical practice and service development.

Forensics

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Publisher : Xlibris Corporation
ISBN 13 : 1664136215
Total Pages : 271 pages
Book Rating : 4.6/5 (641 download)

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Book Synopsis Forensics by : Harry A. Milman PhD

Download or read book Forensics written by Harry A. Milman PhD and published by Xlibris Corporation. This book was released on 2020-10-29 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carrie Fisher, also known as Princess Leia from Star Wars, had been abusing cocaine and other pharmaceuticals for many years, so when it was announced that she died from sleep apnea, I was skeptical. A more plausible explanation would have been that she died from a drug overdose. A review of the medical examiner's report revealed that the Fisher family refused to give permission for an autopsy and toxicology tests to be done. Constrained by these limitations, the coroner labeled the manner of death "undetermined". FORENSICS: The Science behind the Deaths of Famous People is an analysis and description of how coroners determine the cause and manner of death. An investigation of twenty-three deaths of famous people was conducted based on a review of publicly available autopsy and toxicology reports, as well as published scientific and lay articles. Drug use was implicated in 70 percent of the deaths. Four celebrity deaths were the result of suicide or homicide. Four others were from natural causes.

Fundamentals and Applications of Fourier Transform Mass Spectrometry

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Author :
Publisher : Elsevier
ISBN 13 : 0128140143
Total Pages : 778 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Fundamentals and Applications of Fourier Transform Mass Spectrometry by : Philippe Schmitt-Kopplin

Download or read book Fundamentals and Applications of Fourier Transform Mass Spectrometry written by Philippe Schmitt-Kopplin and published by Elsevier. This book was released on 2019-08-11 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

The Addicted Brain

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Author :
Publisher : FT Press
ISBN 13 : 0132542501
Total Pages : 237 pages
Book Rating : 4.1/5 (325 download)

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Book Synopsis The Addicted Brain by : Michael J. Kuhar

Download or read book The Addicted Brain written by Michael J. Kuhar and published by FT Press. This book was released on 2012 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Addicted Brain" explains clearly and vividly what has been learned about how and why some people become addicted and abuse drugs or other substances, the relatively long-term changes these substances can make in the brain, and the progress being made on treatments.

Edwards' Treatment of Drinking Problems

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Publisher : Cambridge University Press
ISBN 13 : 1107519527
Total Pages : 279 pages
Book Rating : 4.1/5 (75 download)

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Book Synopsis Edwards' Treatment of Drinking Problems by : Keith Humphreys

Download or read book Edwards' Treatment of Drinking Problems written by Keith Humphreys and published by Cambridge University Press. This book was released on 2016-04-28 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art, accessible reviews of the science of alcohol treatment and guidance for the management of clinical situations.