Author : National Institute for Health and Care Excellence (Great Britain)
Publisher :
ISBN 13 :
Total Pages : 187 pages
Book Rating : 4.:/5 (115 download)
Book Synopsis Addendum to Psychosis and Schizophrenia in Children and Young People by : National Institute for Health and Care Excellence (Great Britain)
Download or read book Addendum to Psychosis and Schizophrenia in Children and Young People written by National Institute for Health and Care Excellence (Great Britain) and published by . This book was released on 2016 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a substantial increase in the prescription of antipsychotic medications for children and young people with evidence also of a change of use from so-called 'first generation' antipsychotics (FGAs) such as haloperidol to 'second generation' antipsychotics (SGAs) such as olanzapine and risperidone. The latter drugs were introduced and marketed as being more effective and less likely to cause side effects, particularly extrapyramidal movement disorders and parkinsonism. However, weight gain, risk of diabetes, and metabolic problems associated with all SGAs raise important public health concerns given the widespread use of these medications. The surveillance review identified new evidence relating to adverse effects associated with olanzapine, particularly weight gain and metabolic effects, suggesting that olanzapine may not be suitable for first-line treatment in children and young people with first episode psychosis. Weight gain is less of an issue with first generation antipsychotics and so given the nature of the evidence identified by surveillance which was specifically related to weight gain associated with olanzapine, this update aims to compare the side effects profile of olanzapine compared to other second generation antipsychotics.