A Tale of Two Viruses

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Author :
Publisher : University of Pittsburgh Press
ISBN 13 : 0822987716
Total Pages : 394 pages
Book Rating : 4.8/5 (229 download)

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Book Synopsis A Tale of Two Viruses by : Neeraja Sankaran

Download or read book A Tale of Two Viruses written by Neeraja Sankaran and published by University of Pittsburgh Press. This book was released on 2021-03-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell’s genetic material indefinitely, or until induced by UV radiation. But until Lwoff’s discovery of the mechanism of lysogeny, microbiologist Félix d’Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices.

Viruses, Plagues, and History

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Publisher : Oxford University Press, USA
ISBN 13 : 0190056789
Total Pages : 513 pages
Book Rating : 4.1/5 (9 download)

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Book Synopsis Viruses, Plagues, and History by : Michael B. A. Oldstone

Download or read book Viruses, Plagues, and History written by Michael B. A. Oldstone and published by Oxford University Press, USA. This book was released on 2020 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Here, my previous edition of Viruses, Plagues, & History is updated to reflect both progress and disappointment since that publication. This edition describes newcomers to the range of human infections, specifically, plagues that play important roles in this 21st century. The first is Middle East Respiratory Syndrome (MERS), an infection related to Sudden Acute Respiratory Syndrome (SARS). SARS was the first new-found plague of this century. Zika virus, which is similar to yellow fever virus in being transmitted by mosquitos, is another of the recent scourges. Zika appearing for the first time in the Americas is associated with birth defects and a paralytic condition in adults. Lastly, illness due to hepatitis viruses were observed prominently during the second World War initially associated with blood transfusions and vaccine inoculations. Since then, hepatitis virus infections have afflicted millions of individuals, in some leading to an acute fulminating liver disease or more often to a life-long persistent infection. A subset of those infected has developed liver cancer. However, in a triumph of medical treatments for infectious diseases, pharmaceuticals have been developed whose use virtually eliminates such maladies. For example, Hepatitis C virus infection has been eliminated from almost all (>97%) of its victims. This incredible result was the by-product of basic research in virology as well as cell and molecular biology during which intelligent drugs were designed to block events in the hepatitis virus life-cycle"--

Coronaviruses

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Publisher :
ISBN 13 : 9781912530359
Total Pages : 0 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Coronaviruses by : Volker Thiel

Download or read book Coronaviruses written by Volker Thiel and published by . This book was released on 2020-01-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paperback. ISBN 978-1-912530-35-9. In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. Essential reading for all coronavirologists as well as scientists working on other viruses of the respiratory and/or gastrointestinal tract.

The Rainbow Virus Young Adult Edition

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Publisher : Glyphus LLC
ISBN 13 : 0981884857
Total Pages : 392 pages
Book Rating : 4.9/5 (818 download)

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Book Synopsis The Rainbow Virus Young Adult Edition by : Dennis Meredith

Download or read book The Rainbow Virus Young Adult Edition written by Dennis Meredith and published by Glyphus LLC. This book was released on 2013-02 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's the weirdest bioterrorism attack ever! A frightening epidemic of unknown viruses is turning people red, yellow, blue, chartreuse, emerald, pumpkin, fuschia. . . . An eccentric, brilliant biologist vanishes from a local biotech company. Is he the culprit? An unlikely team pursues the mystery: disgraced FBI agent Bobby Loudon and obsessive CDC disease detective Kathleen Shinohara. They race to find the bioterrorist, but they are thwarted by a shadowy, deadly network called the faction. Who is this group and what is their goal? Will Loudon's and Shinohara's worst fear be realized¿that the colorful infections are prelude to an unstoppable virus that the bioterrorist will unleash to devastate the world? The Rainbow Virus is a breakneck science fiction adventure based on the looming potential of new biowarfare technology to pose a global terrorist threat. It's also a witty commentary on the peculiar human tendency to judge people by their skin color. Author and veteran science writer Dennis Meredith has crafted this riveting tale drawing on his decades of experience working at leading research universities such as Caltech, MIT, Cornell and Duke. For more information on Dennis Meredith's novels, go to www.DennisMeredith.com.

The Hot Zone

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Publisher : Anchor
ISBN 13 : 0385479565
Total Pages : 450 pages
Book Rating : 4.3/5 (854 download)

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Book Synopsis The Hot Zone by : Richard Preston

Download or read book The Hot Zone written by Richard Preston and published by Anchor. This book was released on 1995 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The virus kills nine out of ten of its victims. Its effects are so quick and so gruesome that even biohazard experts are terrified. It is airborne, it is extremely contagious, and it is about to burn through the suburbs of Washington, D.C. Is there any way to stop it? This doomsday scenario confronted a biohazard SWAT team struggling in secret to stop the outbreak of an exotic "hot" virus at an Army research facility outside Washington. "The Hot Zone" tells the dramatic story of their dangerous race against time, along with an alarming account of how previously unknown viruses that have lived undetected in the rain forest for eons are now entering human populations. From the airlocked confines of a biosafety level 4 military lab, to an airliner over Kenya carrying a passenger dissolving into a human virus bomb, to a deserted jungle cave alive with deadly virus, THE HOT ZONE is a non-fiction thriller like no other. "The Andromeda Strain" was fiction--- "this is real!"

The Panic Virus

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1439158657
Total Pages : 466 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Panic Virus by : Seth Mnookin

Download or read book The Panic Virus written by Seth Mnookin and published by Simon and Schuster. This book was released on 2012-01-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.

A Shot to Save the World

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Publisher : Penguin
ISBN 13 : 0593420403
Total Pages : 384 pages
Book Rating : 4.5/5 (934 download)

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Book Synopsis A Shot to Save the World by : Gregory Zuckerman

Download or read book A Shot to Save the World written by Gregory Zuckerman and published by Penguin. This book was released on 2021-10-26 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: "An inspiring and informative page-turner." –Walter Isaacson Longlisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the Market Few were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.

A Planet of Viruses

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022632026X
Total Pages : 133 pages
Book Rating : 4.2/5 (263 download)

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Book Synopsis A Planet of Viruses by : Carl Zimmer

Download or read book A Planet of Viruses written by Carl Zimmer and published by University of Chicago Press. This book was released on 2015-10-06 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: For years, scientists have been warning us that a pandemic was all but inevitable. Now it's here, and the rest of us have a lot to learn. Fortunately, science writer Carl Zimmer is here to guide us. In this compact volume, he tells the story of how the smallest living things known to science can bring an entire planet of people to a halt--and what we can learn from how we've defeated them in the past. Planet of Viruses covers such threats as Ebola, MERS, and chikungunya virus; tells about recent scientific discoveries, such as a hundred-million-year-old virus that infected the common ancestor of armadillos, elephants, and humans; and shares new findings that show why climate change may lead to even deadlier outbreaks. Zimmer’s lucid explanations and fascinating stories demonstrate how deeply humans and viruses are intertwined. Viruses helped give rise to the first life-forms, are responsible for many of our most devastating diseases, and will continue to control our fate for centuries. Thoroughly readable, and, for all its honesty about the threats, as reassuring as it is frightening, A Planet of Viruses is a fascinating tour of a world we all need to better understand.

Global Health Impacts of Vector-Borne Diseases

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Author :
Publisher : National Academies Press
ISBN 13 : 0309377595
Total Pages : 397 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Global Health Impacts of Vector-Borne Diseases by : National Academies of Sciences, Engineering, and Medicine

Download or read book Global Health Impacts of Vector-Borne Diseases written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-21 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Viral

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Publisher : HarperCollins
ISBN 13 : 0063273608
Total Pages : 448 pages
Book Rating : 4.0/5 (632 download)

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Book Synopsis Viral by : Matt Ridley

Download or read book Viral written by Matt Ridley and published by HarperCollins. This book was released on 2022-06-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Chan and Ridley write with an urgency...that inspires gripping depictions of what viruses are, how infectious-disease laboratories work and wonderfully lucid descriptions of bats. . . . They powerfully recount how dangerous pathogens can both leak from a lab and emerge in nature." (New York Times Book Review) Understanding how Covid-19 started is crucial for the future of humankind. Viral is the most incisive and authoritative book about the search for the source of the virus. A new virus descended on the human species in 2019 wreaking unprecedented havoc. Finding out where it came from and how it first jumped into people is an urgent priority, but early expectations that this would prove an easy question to answer have been dashed. Nearly two years into the pandemic, the crucial mystery of the origin of SARS-CoV-2 is not only unresolved but has deepened. In this uniquely insightful book, a scientist and a writer join forces to try to get to the bottom of how a virus whose closest relations live in bats in subtropical southern China somehow managed to begin spreading among people more than 1,500 kilometres away in the city of Wuhan. They grapple with the baffling fact that the virus left none of the expected traces that such outbreaks usually create: no infected market animals or wildlife, no chains of early cases in travellers to the city, no smouldering epidemic in a rural area, no rapid adaptation of the virus to its new host—human beings. To try to solve this pressing mystery, Viral delves deep into the events of 2019 leading up to 2021, the details of what went on in animal markets and virology laboratories, the records and data hidden from sight within archived Chinese theses and websites, and the clues that can be coaxed from the very text of the virus’s own genetic code. The result is a gripping detective story that takes the reader deeper and deeper into a metaphorical cave of mystery. One by one the authors explore promising tunnels only to show that they are blind alleys, until, miles beneath the surface, they find themselves tantalisingly close to a shaft that leads to the light.

The Virus

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Publisher : David Fickling Books
ISBN 13 : 1788452119
Total Pages : 152 pages
Book Rating : 4.7/5 (884 download)

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Book Synopsis The Virus by : Ben Martynoga

Download or read book The Virus written by Ben Martynoga and published by David Fickling Books. This book was released on 2020-07-09 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Join science expert Dr Ben Martynoga and illustrator extraordinaire Moose Allain on a fascinating, sometimes funny, and occasionally scary journey through the world of viruses.Explore the science behind viruses and the COVID-19 pandemic in a fascinating story of hijacked human cells and our own internal emergency services.Along the way, you'll learn what viruses are, how they work, and how we can overcome - or at least learn to live alongside - those that do us harm.

Viruses

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Publisher : Oxford University Press
ISBN 13 : 0198811713
Total Pages : 177 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Viruses by : Dorothy H. Crawford

Download or read book Viruses written by Dorothy H. Crawford and published by Oxford University Press. This book was released on 2018 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses are big news. From pandemics such as HIV, swine flu, and SARS, we are constantly being bombarded with information about new lethal infections. In this Very Short Introduction, Dorothy Crawford demonstrates from their discovery and the unravelling of their intricate structures, how clever these entities really are.

The Epstein-Barr Virus

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Publisher : Springer Science & Business Media
ISBN 13 : 3642672361
Total Pages : 467 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis The Epstein-Barr Virus by : M. A. Epstein

Download or read book The Epstein-Barr Virus written by M. A. Epstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.

The Pandemic Century

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Publisher : W H Allen
ISBN 13 : 9780753558287
Total Pages : 0 pages
Book Rating : 4.5/5 (582 download)

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Book Synopsis The Pandemic Century by : Mark Honigsbaum

Download or read book The Pandemic Century written by Mark Honigsbaum and published by W H Allen. This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Financial Times Best Book of the Year The most timely and informative history book you will read this year, tracing a century of pandemics, with a new chapter on COVID-19. Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet, despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu and the 1924 outbreak of pneumonic plague in Los Angeles, to the 1930 'parrot fever' pandemic and the more recent SARS, Ebola, Zika and - now - COVID-19 epidemics, the last 100 years have been marked by a succession of unanticipated pandemic alarms. In The Pandemic Century, Mark Honigsbaum chronicles 100 years of history in 10 outbreaks. Bringing us right up-to-date with a new chapter on COVID-19, this fast-paced, critically-acclaimed book combines science history, medical sociology and thrilling front-line reportage to deliver the story of our times. As we meet dedicated disease detectives, obstructive public health officials, and gifted scientists often blinded by their own expertise, we come face-to-face with the brilliance and medical hubris shaping both the frontier of science - and the future of humanity's survival.

The Immortal Life of Henrietta Lacks

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Author :
Publisher : Crown
ISBN 13 : 0307589382
Total Pages : 386 pages
Book Rating : 4.3/5 (75 download)

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Book Synopsis The Immortal Life of Henrietta Lacks by : Rebecca Skloot

Download or read book The Immortal Life of Henrietta Lacks written by Rebecca Skloot and published by Crown. This book was released on 2010-02-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

Portraits of Viruses

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Author :
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Portraits of Viruses by : Frank Fenner

Download or read book Portraits of Viruses written by Frank Fenner and published by S. Karger AG (Switzerland). This book was released on 1988 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Great Influenza

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Author :
Publisher : Penguin
ISBN 13 : 9780143036494
Total Pages : 580 pages
Book Rating : 4.0/5 (364 download)

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Book Synopsis The Great Influenza by : John M. Barry

Download or read book The Great Influenza written by John M. Barry and published by Penguin. This book was released on 2005-10-04 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 New York Times bestseller “Barry will teach you almost everything you need to know about one of the deadliest outbreaks in human history.”—Bill Gates "Monumental... an authoritative and disturbing morality tale."—Chicago Tribune The strongest weapon against pandemic is the truth. Read why in the definitive account of the 1918 Flu Epidemic. Magisterial in its breadth of perspective and depth of research, The Great Influenza provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. As Barry concludes, "The final lesson of 1918, a simple one yet one most difficult to execute, is that...those in authority must retain the public's trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart." At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.