A Guide to Forensic DNA Profiling

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118751523
Total Pages : 453 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis A Guide to Forensic DNA Profiling by : Scott Bader

Download or read book A Guide to Forensic DNA Profiling written by Scott Bader and published by John Wiley & Sons. This book was released on 2016-03-21 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasingly arcane world of DNA profiling demands that those needing to understand at least some of it must find a source of reliable and understandable information. Combining material from the successful Wiley Encyclopedia of Forensic Science with newly commissioned and updated material, the Editors have used their own extensive experience in criminal casework across the world to compile an informative guide that will provide knowledge and thought-provoking articles of interest to anyone involved or interested in the use of DNA in the forensic context. Following extensive introductory chapters covering forensic DNA profiling and forensic genetics, this comprehensive volume presents a substantial breadth of material covering: Fundamental material – including sources of DNA, validation, and accreditation Analysis and interpretation – including, extraction, quantification, amplification and interpretation of electropherograms (epgs) Evaluation – including mixtures, low template, and transfer Applications – databases, paternity and kinship, mitochondrial-DNA, wildlife DNA, single-nucleotide polymorphism, phenotyping and familial searching Court - report writing, discovery, cross examination, and current controversies With contributions from leading experts across the whole gamut of forensic science, this volume is intended to be authoritative but not authoritarian, informative but comprehensible, and comprehensive but concise. It will prove to be a valuable addition, and useful resource, for scientists, lawyers, teachers, criminologists, and judges.

Genetic Testimony

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Author :
Publisher : Prentice Hall
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Genetic Testimony by : Charlotte Spencer

Download or read book Genetic Testimony written by Charlotte Spencer and published by Prentice Hall. This book was released on 2004 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: For undergraduate courses in introductory-level Human Genetics, Biochemistry, and Molecular Biology courses. Also appropriate as a resource for law schools, legal clinics, and law enforcement offices. Part of the "Prentice Hall Exploring Biology Series", DNA Forensics explores the subject of modern DNA profiling in straightforward language, requiring and is aimed at students with little background in science or biotechnology. It raises controversial questions about the uses and potential misuses of DNA forensics; and illustrates issues by presenting recent criminal cases involving DNA profiling. A valuable resource for undergraduate science students, it introduces basic concepts of genetics and biotechnology in the context of one of the most important developments in modern criminal investigation.

A Guide to Forensic DNA Profiling

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Author :
Publisher :
ISBN 13 : 9781787851108
Total Pages : pages
Book Rating : 4.8/5 (511 download)

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Book Synopsis A Guide to Forensic DNA Profiling by : Allan Jamieson

Download or read book A Guide to Forensic DNA Profiling written by Allan Jamieson and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasingly arcane world of DNA profiling demands that those needing to understand at least some of it must find a source of reliable and understandable information.

Forensic DNA Profiling

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Author :
Publisher : CRC Press
ISBN 13 : 0429671423
Total Pages : 132 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Forensic DNA Profiling by : Jo-Anne Bright

Download or read book Forensic DNA Profiling written by Jo-Anne Bright and published by CRC Press. This book was released on 2019-12-09 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.

Weight-of-Evidence for Forensic DNA Profiles

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111881455X
Total Pages : 232 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Weight-of-Evidence for Forensic DNA Profiles by : David J. Balding

Download or read book Weight-of-Evidence for Forensic DNA Profiles written by David J. Balding and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA evidence is widely used in the modern justice system. Statistical methodology plays a key role in ensuring that this evidence is collected, interpreted, analysed and presented correctly. This book is a guide to assessing DNA evidence and presenting that evidence in a courtroom setting. It offers practical guidance to forensic scientists with little dependence on mathematical ability, and provides the scientist with the understanding they require to apply the methods in their work. Since the publication of the first edition of this book in 2005 there have been many incremental changes, and one dramatic change which is the emergence of low template DNA (LTDNA) profiles. This second edition is edited and expanded to cover the basics of LTDNA technology. The author's own open-source R code likeLTD is described and used for worked examples in the book. Commercial and free software are also covered.

DNA Fingerprinting: Advancements and Future Endeavors

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Author :
Publisher : Springer
ISBN 13 : 9811315833
Total Pages : 325 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis DNA Fingerprinting: Advancements and Future Endeavors by : Hirak Ranjan Dash

Download or read book DNA Fingerprinting: Advancements and Future Endeavors written by Hirak Ranjan Dash and published by Springer. This book was released on 2018-11-01 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and the economics of the DNA fingerprinting technique. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems. Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies.

Weight-of-Evidence for Forensic DNA Profiles

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470867663
Total Pages : 198 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Weight-of-Evidence for Forensic DNA Profiles by : David J. Balding

Download or read book Weight-of-Evidence for Forensic DNA Profiles written by David J. Balding and published by John Wiley & Sons. This book was released on 2005-04-08 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessing Weight-of-Evidence for DNA Profiles is an excellent introductory text to the use of statistical analysis for assessing DNA evidence. It offers practical guidance to forensic scientists with little dependence on mathematical ability as the book includes background information on statistics – including likelihood ratios – population genetics, and courtroom issues. The author, who is highly experienced in this field, has illustrated the book throughout with his own experiences as well as providing a theoretical underpinning to the subject. It is an ideal choice for forensic scientists and lawyers, as well as statisticians and population geneticists with an interest in forensic science and DNA.

Forensic DNA Analyses Made Simple

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Author :
Publisher : CRC Press
ISBN 13 : 1000881164
Total Pages : 147 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Forensic DNA Analyses Made Simple by : Omar Bagasra

Download or read book Forensic DNA Analyses Made Simple written by Omar Bagasra and published by CRC Press. This book was released on 2023-07-13 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequencing genetic material is now common practice. The general population have become consumers of this information but without an understanding of the biological processes that render sequencing data useful. The interpretation of genetic sequence depends on an appreciation of the basics of genetics and the limits of such data. This book provides the background necessary to understand, interpret, and apply sequencing information to real- world problems. Replication of genetic material, the structure of DNA, typing methods, and forensic applications are all discussed in this useful primer. Key Features • Provides self-learning about DNA fingerprinting. • Includes sections on how to analyze and interpret DNA fingerprinting. • Covers legal and medicolegal issues and case analyses. • Teaches novice legal community about DNA fingerprints. • Summarizes for a general audience the role of ancestry, DNA, and what that means.

Forensic DNA Analysis

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Publisher : CRC Press
ISBN 13 : 1000064581
Total Pages : 479 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Forensic DNA Analysis by : Elena Pilli

Download or read book Forensic DNA Analysis written by Elena Pilli and published by CRC Press. This book was released on 2021-03-31 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic DNA Analysis: Technological Development and Innovative Applications provides a fascinating overview of new and innovative technologies and current applications in forensic genetics. Edited by two forensic experts with many years of forensic crime experience with the Italian police and with prestigious academic universities, the volume takes an interdisciplinary perspective, the volume presents an introduction to genome polymorphisms, discusses, forensic genetic markers, presents a variety of new methods and techniques in forensic genetics, and looks at a selection of new technological innovations and inventions now available from commercial vendors. The book is an important resource for scientists, researchers, and other experts in the field who will find it of interest for its exhaustive discussion of the most important technological innovations in forensic genetics. For those newer to the field, the volume will be an invaluable reference guide to the forensic world.

Forensic Analysis of Biological Evidence

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Publisher : CRC Press
ISBN 13 : 1466504587
Total Pages : 176 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Forensic Analysis of Biological Evidence by : J. Thomas McClintock

Download or read book Forensic Analysis of Biological Evidence written by J. Thomas McClintock and published by CRC Press. This book was released on 2017-08-02 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful tool in the identification of individuals, DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories, Forensic Analysis of Biological Evidence: A Laboratory

Forensic DNA Transfer

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Publisher :
ISBN 13 : 9781003158844
Total Pages : 0 pages
Book Rating : 4.1/5 (588 download)

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Book Synopsis Forensic DNA Transfer by : Jane Moira Taupin

Download or read book Forensic DNA Transfer written by Jane Moira Taupin and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Forensic DNA Transfer provides a guide to the recognition and current understanding of DNA transfer in forensic criminal investigations. Increased improvements in technology mean that it is now routinely possible to obtain DNA profiles from non-visible deposits. How or when the DNA in question was deposited may be an issue in the context of the case, especially if the donor of the DNA is not in dispute. A DNA profile alone cannot reveal when or how that DNA was deposited at a crime scene, nor can it reveal the body matter from which it originated. Issues of transfer associated with activities may be debated - which the traditional discrimination purpose of DNA profiling cannot address"--

Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles

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Publisher : Academic Press
ISBN 13 : 0128205687
Total Pages : 532 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles by : Peter Gill

Download or read book Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles written by Peter Gill and published by Academic Press. This book was released on 2020-06-10 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past twenty years, there’s been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting ‘probabilistic genotyping’ to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner’s Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience Covers short tandem repeat (STR) analysis, including database searching and massive parallel sequencing (both STRs and SNPs) Encourages dissemination and understanding of probabilistic genotyping by including practical examples of varying complexity Written by authors intimately involved with software development, training at international workshops and reporting cases worldwide using the methods described in this book

Interpreting Complex Forensic DNA Evidence

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Publisher : CRC Press
ISBN 13 : 1351023764
Total Pages : 117 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Interpreting Complex Forensic DNA Evidence by : Jane Moira Taupin

Download or read book Interpreting Complex Forensic DNA Evidence written by Jane Moira Taupin and published by CRC Press. This book was released on 2019-11-14 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interpreting Complex Forensic DNA Evidence is a handy guide to recent advances—and emerging issues—in interpreting complex DNA evidence and profiles for use in criminal investigations. In certain cases, DNA cannot be connected to a specific biological material such as blood, semen or saliva. How or when the DNA was deposited may be an issue. The possibility of generating DNA profiles from touched objects, where there may not be a visible deposit, has expanded the scope and number of exhibits submitted for DNA analysis. With such advances, and increasing improvements in technological capabilities in testing samples, this means it is possible to detect ever smaller amounts of DNA. There are also many efforts underway to seek was to interpret DNA profiles that are sub-optimal—either relative to the amount required by the testing kit and, potentially, the quality of the obtained sample. Laboratories often use enhancements in order to obtain a readable DNA profile. The broad-reaching implications of improving DNA sensitivity have led to this next, emerging generation of more complex profiles. Examples partial profiles that do not faithfully reflect the proposed donor, or mixtures of partial DNA from multiple people. A complexity threshold has been proposed to limit interpretation of poor-quality data. Research is now addressing the interpretation of transfer of trace amounts of DNA. Complex issues are arising in trial that need to be reconciled as such complexity has added challenges to the interpretation of evidence and its introduction or dismissal in certain cases in the courts. Key Features: Addresses DNA transfer, from person-to-person as well as to objects Outlines each stage required to produce a DNA profile from an exhibit—including collection, handling, storage, and analysis Discusses ethics, subjectivity, and bias—including cognitive dissonance—as they relate specifically to complex DNA evidence Highlights current techniques and the latest advances in DNA analysis, including advances in familial DNA searches Interpreting Complex Forensic DNA Evidence provides tools to assist the criminal investigator, forensic expert, and legal professional when posed with a DNA result in a forensic report or testimony. The result—and any associated statistic—may not reveal any ambiguity, complexity, or the assumptions involved in deriving it. Questions from resolved criminal cases are posed, and the relevant forensic literature, provided for the reader to assess a DNA result and any associated statistic. Case studies throughout illustrate concepts and emphasize the need for conclusions in the forensic report that are supported by the data.

Statistical DNA Forensics

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Publisher : John Wiley & Sons
ISBN 13 : 9780470727034
Total Pages : 262 pages
Book Rating : 4.7/5 (27 download)

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Book Synopsis Statistical DNA Forensics by : Wing Kam Fung

Download or read book Statistical DNA Forensics written by Wing Kam Fung and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methodology plays a key role in ensuring that DNA evidence is collected, interpreted, analyzed and presented correctly. With the recent advances in computer technology, this methodology is more complex than ever before. There are a growing number of books in the area but none are devoted to the computational analysis of evidence. This book presents the methodology of statistical DNA forensics with an emphasis on the use of computational techniques to analyze and interpret forensic evidence.

DNA in the Courtroom

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Publisher : DNA in the Courtroom
ISBN 13 : 9780964450707
Total Pages : 156 pages
Book Rating : 4.4/5 (57 download)

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Book Synopsis DNA in the Courtroom by : Howard Coleman

Download or read book DNA in the Courtroom written by Howard Coleman and published by DNA in the Courtroom. This book was released on 1994 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear and comprehensive guide to the scientific and legal issues surrounding forensic DNA testing.

Introduction to Forensic DNA Analysis

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Publisher : CRC Press
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Introduction to Forensic DNA Analysis by : Keith Inman

Download or read book Introduction to Forensic DNA Analysis written by Keith Inman and published by CRC Press. This book was released on 1997-02-07 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes the advantages and limitations of using DNA techniques for the presentation of evidence in the courtroom and in the general development of various types of criminal cases. The authors present the material in an understandable manner for use by professionals in the legal system, as well as those in the fields of forensics and law enforcement. Coverage includes: Key terminology used in the field The scientific basis of DNA typing Statistical interpretations of DNA typing A summary of court decisions and admissibility standards

Fundamentals of Forensic DNA Typing

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Publisher : Academic Press
ISBN 13 : 0080961762
Total Pages : 519 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Fundamentals of Forensic DNA Typing by : John M. Butler

Download or read book Fundamentals of Forensic DNA Typing written by John M. Butler and published by Academic Press. This book was released on 2009-09-30 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key