YEAR OF THE COMET.

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Publisher :
ISBN 13 : 9781800249240
Total Pages : pages
Book Rating : 4.2/5 (492 download)

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Book Synopsis YEAR OF THE COMET. by : SERGEI. LEBEDEV

Download or read book YEAR OF THE COMET. written by SERGEI. LEBEDEV and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

30 years of the Comet Assay: an overview with some new insights

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Publisher : Frontiers Media SA
ISBN 13 : 2889196496
Total Pages : 176 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis 30 years of the Comet Assay: an overview with some new insights by : Amaya Azqueta

Download or read book 30 years of the Comet Assay: an overview with some new insights written by Amaya Azqueta and published by Frontiers Media SA. This book was released on 2015-08-21 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: By means of this ‘Frontiers in Genetics’ research topic, we are celebrating 30 years of the Comet Assay. The first paper on this single-cell gel electrophoresis assay was published in 1984 by O. Ostling and K.J. Johanson (Biochem. Biophys. Res. Commun. Vol.123: 291-298). The comet assay is a versatile and sensitive method for measuring single - and double-strand breaks in DNA. By including lesion-specific enzymes in the assay, its range and sensitivity are greatly increased, but it is important to bear in mind that their specificity is not absolute. The comet assay (with and without inclusion of lesion-specific enzymes) is widely used as a biomarker assay in human population studies - primarily to measure DNA damage, but increasingly also to assess the capacity of cells for DNA repair. Ostling and Johanson (Biochem. Biophys. Res. Commun., 1984) were also the first to report experiments to measure DNA repair, by simply following the decrease of DNA damage over time after challenging cells with ionising radiation. However, this approach is time-consuming and laborious as it requires an extended period of cell culture and is therefore not ideal for biomonitoring studies, which typically require high-throughput processing of many samples. As an alternative approach, the in vitro comet-based repair assay was developed: a cell extract is incubated with a DNA substrate containing specific lesions, and DNA incisions accumulate. The in vitro comet-based repair assay has been modified and improved over the past decade: it was first devised to measure base excision repair of oxidised purines in lymphocytes (Collins et al., Mutagenesis, 2001), but has since been adapted for other lesions and thus other repair pathways, as well as being applied to tissue samples in addition to cell suspensions. Even after 30 years, the comet assay is still in a growth phase, with many new users each year. Many questions are repeatedly raised, which may seem to have self-evident answers, but clearly, it is necessary to reiterate them for the benefit of the new audience, and sometimes being forced to think again about old topics can shed new light. Different applications of the comet assay are discussed in this special issue, including: genotoxicity testing in different organisms, human biomonitoring, DNA repair studies, environmental biomonitoring and clinical studies. Furthermore, we consider and where possible answer questions, including the ones raised by Raymond Tice at the 8th International Comet Assay Workshop in Perugia (Italy 2009): What is the spectrum of DNA damage detected by the various versions of the comet assay?; What are the limitations associated with each application?; What should be done to standardize the assay for biomonitoring studies?; Can the comet assay be used to monitor changes in global methylation status?; What cell types are suitable for detecting genotoxic substances and their effects in vivo and in vitro?; Can the assay be fully automated?; and more. So this ‘Frontiers in Genetics’ research topic is written for the beginner as well as for the experienced users of the comet assay.

In the Days of the Comet

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ISBN 13 :
Total Pages : 394 pages
Book Rating : 4.:/5 (37 download)

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Book Synopsis In the Days of the Comet by : Herbert George Wells

Download or read book In the Days of the Comet written by Herbert George Wells and published by . This book was released on 1906 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heart of the Comet

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Publisher :
ISBN 13 : 9780984915460
Total Pages : 513 pages
Book Rating : 4.9/5 (154 download)

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Book Synopsis Heart of the Comet by : Gregory Benford

Download or read book Heart of the Comet written by Gregory Benford and published by . This book was released on 2012-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A group of men and women, from a shattered society, ride a ball of ice through the solar system in search of a future.

The Comet's Curse

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Publisher : Macmillan
ISBN 13 : 0765321076
Total Pages : 240 pages
Book Rating : 4.7/5 (653 download)

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Book Synopsis The Comet's Curse by : Dom Testa

Download or read book The Comet's Curse written by Dom Testa and published by Macmillan. This book was released on 2009-01-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Desperate to save the human race after a comet's deadly particles devastate the adult population, scientists create a ship that will carry a crew of 251 teenagers to a home in a distant solar system.

The Night of the Comet

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Publisher :
ISBN 13 : 0345516001
Total Pages : 338 pages
Book Rating : 4.3/5 (455 download)

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Book Synopsis The Night of the Comet by : George Bishop (Jr.)

Download or read book The Night of the Comet written by George Bishop (Jr.) and published by . This book was released on 2013 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fourteen-year-old Alan Broussard is swept up in his science teacher father's community-wide comet-watching activities, which illuminate for the young teen his father's inadequacies, his mother's unhappiness, and his own loss of innocence.

The Comet

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Publisher : Graphic Arts Books
ISBN 13 : 1513298348
Total Pages : 19 pages
Book Rating : 4.5/5 (132 download)

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Book Synopsis The Comet by : W. E. B. Du Bois

Download or read book The Comet written by W. E. B. Du Bois and published by Graphic Arts Books. This book was released on 2021-06-08 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Comet (1920) is a science fiction story by W. E. B. Du Bois. Written while the author was using his role at The Crisis, the official magazine of the NAACP, to publish emerging black artists of the Harlem Renaissance, The Comet is a pioneering work of speculative fiction which imagines a catastrophic event not only decimating New York City, but bringing an abrupt end to white supremacy. “How silent the street was! Not a soul was stirring, and yet it was high-noon—Wall Street? Broadway? He glanced almost wildly up and down, then across the street, and as he looked, a sickening horror froze in his limbs.” Sent to the vault to retrieve some old records, bank messenger Jim Davis emerges to find a city descended into chaos. A comet has passed overhead, spewing toxic fumes into the atmosphere. All of lower Manhattan seems frozen in time. It takes him a few moments to see the bodies, piled into doorways and strewn about the eerily quiet streets. When he comes to his senses, he finds a wealthy woman asking for help. Soon, it becomes clear that they could very well be the last living people in the planet, that the fate of civilization depends on their ability to come together, not as black and white, but as two human beings. But how far will this acknowledgment take them? With a beautifully designed cover and professionally typeset manuscript, this edition of W. E. B. Du Bois’ The Comet is a classic work of African American literature reimagined for modern readers.

The Comet of 1577

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Publisher : Рипол Классик
ISBN 13 : 588224384X
Total Pages : 488 pages
Book Rating : 4.8/5 (822 download)

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Book Synopsis The Comet of 1577 by : C.D. Hellman

Download or read book The Comet of 1577 written by C.D. Hellman and published by Рипол Классик. This book was released on 1971 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Night of the Comet

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Publisher : Ballantine Books
ISBN 13 : 034553879X
Total Pages : 338 pages
Book Rating : 4.3/5 (455 download)

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Book Synopsis The Night of the Comet by : George Bishop

Download or read book The Night of the Comet written by George Bishop and published by Ballantine Books. This book was released on 2013-07-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: NAMED ONE OF THE BEST BOOKS OF THE YEAR BY KIRKUS REVIEWS From the acclaimed author of Letter to My Daughter comes an engrossing coming-of-age tale that deftly conveys the hopes and heartaches of adolescence and the unfulfilled dreams that divide a family, played out against the backdrop of a small southern town in 1973. For his fourteenth birthday, Alan Broussard, Jr., receives a telescope from his father, a science teacher at the local high school who’s eagerly awaiting what he promises will be the astronomical event of the century: the coming of Comet Kohoutek. For Alan Broussard, Sr.—frustrated in his job, remote from his family—the comet is a connection to his past and a bridge to his son, with whom he’s eager to share his love for the stars. But the only heavenly body Junior has any interest in is his captivating new neighbor and classmate, Gabriella Martello, whose bedroom sits within eyeshot of his telescope’s lens. Meanwhile, his mother, Lydia, sees the comet—and her husband’s obsession with it—as one more thing that keeps her from the bigger, brighter life she once imagined for herself far from the swampy environs of Terrebonne, Louisiana. With Kohoutek drawing ever closer, the family begins to crumble under the weight of expectations, until a startling turn of events will leave both father and son much less certain about the laws that govern their universe. Illuminating and unforgettable, The Night of the Comet is a novel about the perils of growing up, the longing for connection, and the idea that love and redemption can be found among the stars. Praise for The Night of the Comet “A quiet, occasionally bittersweet novel about the differences between desire and disappointment, expectations and reality.”—Booklist “Coming-of-age novels examine youthful revelations about the world—filled with cynicism and wonder and rearranged expectations—and the quality hinges on the honesty of the voice, the truth of the observations, the handling of innocence lost; Bishop succeeds on all these fronts.”—Kirkus Reviews “Resonant . . . explores the complexities of a father-son relationship through science, astronomy, and the growing pains of adolescence. . . . Bishop’s characterizations of young Alan’s mother, father, and sister Megan are endearing and their relentless coddling of their maturing son is wincingly accurate.”—Publishers Weekly “Hilarious and heart-wrenching, ethereal and earthy, The Night of the Comet points us to the fragile universe of dreams and disappointments, joy and tragedy, saying here it is, all of it: feast your eyes on the magic. It’s a heavenly book. Nobody writes about the gravitational pull of parent-child relationships—all that we yearn for and all that we can’t have—like George Bishop.”—Minrose Gwin, author of The Queen of Palmyra “Equally sweet and sad, this is a fine novel of love and forgiveness.”—Stewart O’Nan, author of Snow Angels “Bishop’s one of our best, and this book’s a quiet marvel.”—Josh Russell, author of Yellow Jack “A deft, clear-eyed, and sensitive examination of the mysterious bonds of family, the allure of the unattainable, and love and desire—and their consequences—in all their many forms.”—Ellen Baker, author of I Gave My Heart to Know This

A judgement of the comet ... visible ... in Dublin, December ... 1680. By a Person of Quality [Bishop E. Wetenhall].

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Publisher :
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4.0/5 (21 download)

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Book Synopsis A judgement of the comet ... visible ... in Dublin, December ... 1680. By a Person of Quality [Bishop E. Wetenhall]. by :

Download or read book A judgement of the comet ... visible ... in Dublin, December ... 1680. By a Person of Quality [Bishop E. Wetenhall]. written by and published by . This book was released on 1682 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Comet of 1556

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Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.R/5 (5 download)

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Book Synopsis The Comet of 1556 by : John Russell Hind

Download or read book The Comet of 1556 written by John Russell Hind and published by . This book was released on 1857 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Almanack for the Year of Our Lord ...

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Publisher :
ISBN 13 :
Total Pages : 1082 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis An Almanack for the Year of Our Lord ... by : Joseph Whitaker

Download or read book An Almanack for the Year of Our Lord ... written by Joseph Whitaker and published by . This book was released on 1926 with total page 1082 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oblivion

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Publisher : New Vessel Press
ISBN 13 : 1939931290
Total Pages : 300 pages
Book Rating : 4.9/5 (399 download)

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Book Synopsis Oblivion by : Sergei Lebedev

Download or read book Oblivion written by Sergei Lebedev and published by New Vessel Press. This book was released on 2016-01-18 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This acclaimed twenty-first–century Russian novel is “a Dantean descent” into the abandoned Soviet gulags, written “with a clear poetic sensibility” (The Wall Street Journal). In Sergei Lebedev’s debut novel, an unnamed young man travels to the vast wastelands of the Far North to uncover the truth about a mysterious neighbor who once saved his life, and whom he knows only as Grandfather II. What he finds among the forgotten mines and decrepit barracks of former gulags is a world relegated to oblivion, where it is easier to ignore both the victims and the executioners than to come to terms with a terrible past. This disturbing tale evokes the great and ruined beauty of a land where man and machine work in tandem with nature to destroy millions of lives during the Soviet century. Emerging from today’s Russia, where the ills of the past are being forcefully erased from public memory, this masterful novel is an epic literary act of bearing witness, attempting to rescue history from the brink of oblivion. A Wall Street Journal Top 10 Novel of the Year “Not since Alexander Solzhenitsyn has Russia had a writer as obsessed as Sergei Lebedev with that country’s history or the traces it has left on the collective consciousness . . . The best of Russia’s younger generation of writers.” ―The New York Review of Books

The Year of the Comet

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Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.:/5 (34 download)

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Book Synopsis The Year of the Comet by : John Christopher

Download or read book The Year of the Comet written by John Christopher and published by . This book was released on 1955 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Comet ...

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ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis The Comet ... by : François Arago

Download or read book The Comet ... written by François Arago and published by . This book was released on 1843 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Miscellaneous Reflections, Occasion'd by the Comet which Appear'd in December 1680

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Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.:/5 (334 download)

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Book Synopsis Miscellaneous Reflections, Occasion'd by the Comet which Appear'd in December 1680 by : Pierre Bayle

Download or read book Miscellaneous Reflections, Occasion'd by the Comet which Appear'd in December 1680 written by Pierre Bayle and published by . This book was released on 1708 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Comet. Scientific Notices of Comets in General and in Particular of the Comet of 1832 ... Translated ... by Colonel C. Gold

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Publisher :
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.0/5 (24 download)

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Book Synopsis The Comet. Scientific Notices of Comets in General and in Particular of the Comet of 1832 ... Translated ... by Colonel C. Gold by : Dominique François J. Arago

Download or read book The Comet. Scientific Notices of Comets in General and in Particular of the Comet of 1832 ... Translated ... by Colonel C. Gold written by Dominique François J. Arago and published by . This book was released on 1833 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: