The Wilms' Tumor (WT1) Gene

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Author :
Publisher : Humana
ISBN 13 : 9781493940219
Total Pages : 0 pages
Book Rating : 4.9/5 (42 download)

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Book Synopsis The Wilms' Tumor (WT1) Gene by : Nicholas Hastie

Download or read book The Wilms' Tumor (WT1) Gene written by Nicholas Hastie and published by Humana. This book was released on 2016-07-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a thorough overview of the Wilms’ Tumour Gene (WT1). The book begins with three review chapters that cover the involvement of WT1 in pediatric cancer, kidney disease, and tissue development and homeostasis. The next few chapters discuss cell marking and lineage tracing, epicardial cell methodology, colony forming assays for bone marrow stem cells, angiogenesis assays and zebrafish tools. The next group of chapters explores the latest tools in genomics, molecular biology, and biochemistry. They discuss dissecting transcription factor function in cell free systems, ChiP seq, proteomics, RNA interactome, and multiphoton imaging of lipids, measuring the binding constants of protein-nucleic acid interactions, and bioinformatics approaches for analyzing Next Generation Sequence data. The final chapter discusses protocols for clinical trials for immune therapy using anti-WT1 peptides. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, The Wilms’ Tumour (WT1) Gene: Methods and Protocols is a valuable resource for anyone who is interested in the diverse methodologies used in WT1 research.

Wilms Tumor

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Author :
Publisher :
ISBN 13 : 9780994438119
Total Pages : pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis Wilms Tumor by : Marry M. van den Heuvel-Eibrink

Download or read book Wilms Tumor written by Marry M. van den Heuvel-Eibrink and published by . This book was released on 2016-03-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Wilms tumor is a rare kidney cancer that is usually diagnosed in children under the age of six. Wilms tumor is mostly the result of aberrations in WT1 gene, located on chromosome 11p13. In addition to being a risk factor for Wilms tumor, WT1 aberrations cause extra renal complications and other malignancies. This book brings together the basic and clinical aspects of Wilms tumor and WT1 research under three sections. Section I provides a comprehensive guide to the epidemiology, diagnostics, management, and treatment of Wilms tumor. Section II covers the biological aspects of Wims tumor and WT1. Section III focuses on the role of WT1 in cardiac development, prostate cancer, glioblastoma and minimal residual disease.

Handbook of Pediatric Surgery

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1848821328
Total Pages : 492 pages
Book Rating : 4.8/5 (488 download)

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Book Synopsis Handbook of Pediatric Surgery by : Chandrasen K. Sinha

Download or read book Handbook of Pediatric Surgery written by Chandrasen K. Sinha and published by Springer Science & Business Media. This book was released on 2010-06-25 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual surgical or paediatric text books. This book will give a concise overview of all important topics and is designed to provide information in order to recognise the common surgical conditions; namely typical symptoms and signs, investigation and then treatment management. It will also provide an anatomical and physiological background to aid understanding, in addition to emphasising logical, and where possible, evidence-based practice by the use of flow charts, tables and algorithms. Authored by an international range of leading contributors, this is the first book of its kind to offer comprehensive coverage to this topic in a quick reference, pocket-book format.

Renal Tumors of Childhood

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Author :
Publisher : Springer
ISBN 13 : 9783662519189
Total Pages : 0 pages
Book Rating : 4.5/5 (191 download)

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Book Synopsis Renal Tumors of Childhood by : Kathy Pritchard-Jones

Download or read book Renal Tumors of Childhood written by Kathy Pritchard-Jones and published by Springer. This book was released on 2016-10-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. All of the authors are experts from Europe and North America and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.

Preoperative (Neoadjuvant) Chemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642826717
Total Pages : 172 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz

Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Nephron-Sparing Surgery

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Author :
Publisher : CRC Press
ISBN 13 : 0203089928
Total Pages : 166 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Nephron-Sparing Surgery by : Krishna Sasidharan

Download or read book Nephron-Sparing Surgery written by Krishna Sasidharan and published by CRC Press. This book was released on 2007-10-18 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the rising popularity of the minimally invasive laparoscopic option, open nephron-sparing surgery is still seen by many experts as the 'gold standard' for open surgery for kidney tumors and should remain the first choice for many patients. This challenges the idea that less-invasive therapies are always more desirable than open surgery. Whi

Pediatric Radiation Oncology

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Author :
Publisher : Springer
ISBN 13 : 3319435450
Total Pages : 462 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Pediatric Radiation Oncology by : Thomas E. Merchant

Download or read book Pediatric Radiation Oncology written by Thomas E. Merchant and published by Springer. This book was released on 2018-03-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.

Autumn Ivy Cannon

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Author :
Publisher : iUniverse
ISBN 13 : 1475982577
Total Pages : 321 pages
Book Rating : 4.4/5 (759 download)

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Book Synopsis Autumn Ivy Cannon by : Juliet Knowles

Download or read book Autumn Ivy Cannon written by Juliet Knowles and published by iUniverse. This book was released on 2013-04 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Juliet Knowles began writing a blog about her daughter's fight with cancer as a way to reach out to others in the same situation, and her work became a personal story of survival. Now she offers her perspective on that struggle in Autumn Ivy Cannon. Juliet's daughter, Autumn, is a wonderful, beautiful, and strong little girl who had a very rough and exhausting fourth year of her life. She was diagnosed with a form of kidney cancer just two months after her fourth birthday. For Juliet, hearing that her child had cancer seemed unbelievable, unmanageable, and unreal. It felt as if she were witnessing someone else's life from a distance, something she believes was a way of protecting her own emotions from the tragedy. Now, looking back, she recalls her experiences of facing that tremendous challenge and learning of her own capacity for strength and endurance. Juliet began writing during Autumn's cancer diagnosis and treatment in the beginning of 2011. It was an intense year, full of anxiety and frustration as well as moments of truly understanding both life's brevity and its greatness. Sifting through photos and rereading the passages she wrote during the past year throughout Autumn's recovery has helped her to heal, reach out, and share her story with others.

Cancer Incidence and Survival Among Children and Adolescents

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Author :
Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Cancer Incidence and Survival Among Children and Adolescents by :

Download or read book Cancer Incidence and Survival Among Children and Adolescents written by and published by . This book was released on 1999 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neonatal Surgery

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Author :
Publisher : Springer
ISBN 13 : 3319935348
Total Pages : 727 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Neonatal Surgery by : Mario Lima

Download or read book Neonatal Surgery written by Mario Lima and published by Springer. This book was released on 2019-04-13 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, up-to-date reference on surgery in the neonate presents and explains the latest developments in the diagnosis and treatment of neonatal malformations and surgical pathologies. The coverage includes conditions involving the head and neck and the chest, disorders of the liver and biliary tract, gastrointestinal disorders, genitourinary conditions and malformations, anterior abdominal wall defects, tumors, and various other pathologies. For each condition, the pathogenesis and the most current and innovative surgical, and also medical, approaches are described with the aid of numerous illustrations. Minimally invasive strategies receive particular attention, and tips and tricks that will be of value in clinical practice are highlighted. The book includes a general part covering topics such as embryology, anatomy, prenatal diagnosis, and anesthesia and also provides detailed advice on pre- and postoperative care, with special consideration of nutritional problems. Neonatal Surgery will serve as an excellent guide for all pediatric and neonatal surgeons, whether in training or experienced

Common Surgical Diseases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1475729456
Total Pages : 527 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Common Surgical Diseases by : Jonathan A. Myers

Download or read book Common Surgical Diseases written by Jonathan A. Myers and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a concise manner, this book presents common surgical problems encountered by medical students and residents. The book provides easy access for residents before teaching rounds, lectures, etc. The algorithm approach lends itself to rapid learning, making the book a must for every surgical resident.

Pearls and Tricks in Pediatric Surgery

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Author :
Publisher : Springer Nature
ISBN 13 : 3030510670
Total Pages : 522 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Pearls and Tricks in Pediatric Surgery by : Martin Lacher

Download or read book Pearls and Tricks in Pediatric Surgery written by Martin Lacher and published by Springer Nature. This book was released on 2020-10-29 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing core information on pediatric surgery, this book serves as a supplement to standard pediatric surgical textbooks. It offers pearls of wisdom that will help those who participate in pediatric surgical care, as well as to provide state-of-the-art insights based on physiological principles, literature reviews, and clinical experience. This book is an ideal tool to help readers prepare for questions they will be asked on ward rounds, in the OR, or in oral exams. The depth of exploration is intended for medical students, residents in pediatrics and pediatric surgery, pediatric surgical trainees, pediatric nurse practitioners, primary care pediatricians, and family practitioners.

Essentials of Surgical Pediatric Pathology

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1316124150
Total Pages : pages
Book Rating : 4.3/5 (161 download)

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Book Synopsis Essentials of Surgical Pediatric Pathology by : Marta C. Cohen

Download or read book Essentials of Surgical Pediatric Pathology written by Marta C. Cohen and published by Cambridge University Press. This book was released on 2015-02-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Surgical Pediatric Pathology is a clear and practical yet comprehensive guide for trainee pediatric pathologists and non-pediatric pathologists. Each chapter corresponds to one of the main subspecialties, such as dermatopathology, head and neck pathology, and system pathology. Practical guidance is given on handling pediatric specimens and the authors highlight the ways in which common conditions present differently in adults and children. Other chapters cover conditions typical of childhood, including soft tissue tumors and blue round cell tumors. The chapters begin with a brief clinical presentation, followed by a clear macroscopical and histological description of the principal pathologies seen in children. Up-to-date genetic and immunohistochemical information is provided, and the book includes hundreds of high-quality color images. Written and edited by leading international experts in the field, this is an essential resource for trainee pediatric pathologists, as well as general pathologists who may encounter pediatric cases.

What You Need to Know about Wilms' Tumor

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Author :
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.3/5 (126 download)

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Book Synopsis What You Need to Know about Wilms' Tumor by : National Cancer Institute (U.S.). Office of Cancer Communications

Download or read book What You Need to Know about Wilms' Tumor written by National Cancer Institute (U.S.). Office of Cancer Communications and published by . This book was released on 1980 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Operative General Surgery in Neonates and Infants

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Author :
Publisher : Springer
ISBN 13 : 4431558764
Total Pages : 402 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Operative General Surgery in Neonates and Infants by : Tomoaki Taguchi

Download or read book Operative General Surgery in Neonates and Infants written by Tomoaki Taguchi and published by Springer. This book was released on 2016-06-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on standard operative techniques for important diseases in pediatric surgery, especially in neonates and infants, while also offering a wealth of schematic drawings and photographs to help readers understand the surgical techniques. Because of the rarity of the diseases and shortage of advising doctors, operative techniques for neonatal and infant surgery are difficult to learn. In order to understand essential operative procedures, schematic drawings and suitable intraoperative photographs are called for. Operative General Surgery in Neonates and Infants was written by leading experts in pediatric surgery with extensive experience in their respective fields. The contents provide detailed practical advice on the surgical procedures and perioperative management in neonates and infants. This book is a valuable guide for trainees and a helpful refresher text for specialized pediatric surgeons and can also be used to explain operative procedures to parents.

What You Need to Know about Wilms' Tumor

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Author :
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis What You Need to Know about Wilms' Tumor by :

Download or read book What You Need to Know about Wilms' Tumor written by and published by . This book was released on 1982 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Target Volume Delineation for Pediatric Cancers

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Author :
Publisher : Springer
ISBN 13 : 3319691406
Total Pages : 282 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Target Volume Delineation for Pediatric Cancers by : Stephanie A. Terezakis

Download or read book Target Volume Delineation for Pediatric Cancers written by Stephanie A. Terezakis and published by Springer. This book was released on 2018-12-31 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is designed to provide the radiation oncologist with clear practical guidance in the delineation of tumor volumes and/or radiation fields for a wide variety of pediatric cancers, including the most frequently encountered malignancies of childhood. This is a guide to designing treatment fields and volumes that may be utilized in the delivery of conformal therapies such as intensity-modulated radiation therapy and proton therapy, the latter being particularly relevant in children. Each chapter focuses on a specific tumor type, providing general guidelines that will assist the reader in delineating the clinical target volume for particular presentations, including patterns of spread. As the target volumes can be complex, detailed illustrations are presented of the volumes in representative cases, contoured slice by slice on the planning CT images. In addition to target volume delineation for conformal treatment, field design setup for conventional approaches is also discussed.