Wild Immunology—The Answers Are Out There

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Publisher : Frontiers Media SA
ISBN 13 : 2889458091
Total Pages : 191 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Wild Immunology—The Answers Are Out There by : Gregory M. Woods

Download or read book Wild Immunology—The Answers Are Out There written by Gregory M. Woods and published by Frontiers Media SA. This book was released on 2019-03-20 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Go into partnership with nature; she does more than half the work and asks none of the fee.” - Martin H. Fisher. Nature has undertaken an immense amount of work throughout evolution. The evolutionary process has provided a power of information that can address key questions such as - Which immune molecules and pathways are conserved across species? Which molecules and pathways are exploited by pathogens to cause disease? What methods can be broadly used or readily adapted for wild immunology? How does co-infection and exposure to a dynamic environment affect immunity? Section 1 addresses these questions through an evolutionary approach. Laboratory mice have been instrumental in dissecting the nuances of the immune system. The first paper investigates the immunology of wild mice and reviews how evolution and ecology sculpt differences in the immune responses of wild mice and laboratory mice. A better understanding of wild immunology is required and sets the scene for the subsequent papers. Although nature doesn't ask for a fee, it is appropriate that nature is repaid in one form or another. The translational theme of the second section incorporates papers that translate wild immunology back to nature. But any non-human, non-laboratory mouse research environment is hindered by a lack of research tools, hence the underlying theme throughout the second section. Physiological resource allocation is carefully balanced according to the most important needs of the body. Tissue homeostasis can involve trade-offs between energy requirements of the host and compensatory mechanisms to respond to infection. The third section comprises a collection of papers that employ novel strategies to understand how the immune system is compensated under challenging physiological situations. Technology has provided substantial advances in understanding the immune system at cellular and molecular levels. The specificity of these tools (e.g. monoclonal antibodies) often limits the study to a specific species or strain. A consequence of similar genetic sequences or cross-reactivity is that the technology can be adapted to wild species. Section 4 provides two examples of probing wild immunology by adapting technology developed for laboratory species.

Wild Immunology - The Answers Are Out There

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Wild Immunology - The Answers Are Out There by : Gregory M. Woods

Download or read book Wild Immunology - The Answers Are Out There written by Gregory M. Woods and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

The Handy Anatomy Answer Book

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Publisher : Visible Ink Press
ISBN 13 : 1578595886
Total Pages : 386 pages
Book Rating : 4.5/5 (785 download)

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Book Synopsis The Handy Anatomy Answer Book by : Patricia Barnes-Svarney

Download or read book The Handy Anatomy Answer Book written by Patricia Barnes-Svarney and published by Visible Ink Press. This book was released on 2016-01-18 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: We all have one. The human body. But do we really know all of its parts and how they work? The Handy Anatomy Answer Book is the key to unlocking this door to a wondrous world. Covering all the major body systems—integumentary (skin, hair, etc.), skeletal, muscular, nervous, sensory, endocrine, cardiovascular, lymphatic, respiratory, digestive, urinary, and reproductive, and, for good measure, adds chapters on growth and development and how science can help and augment the body—it follows the fascinating maze of organ systems and shows how much the body does routinely just to let you move, breathe, eat, and fight off disease. This handy reference helps make the language of anatomy—as well as physiology and pathology—more understandable and less intimidating. Fascinating trivia, plus serious facts, combine to answer over 1,200 questions about the human body, including What is Gray’s Anatomy? What does it mean to have 20/20 vision? Why is blood sticky? How does exercise affect the heart? What is “gluten intolerance”? Is urine always yellow in color? What are the seven warning signs of Alzheimer’s disease? What is a reflex? How much sleep does an individual need? Can humans use organs from other animals for transplants?

Avian Immunology

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Publisher : Academic Press
ISBN 13 : 012819071X
Total Pages : 627 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Avian Immunology by : Bernd Kaspers

Download or read book Avian Immunology written by Bernd Kaspers and published by Academic Press. This book was released on 2021-12-05 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avian Immunology, Third Edition contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers, include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. With contributions from the foremost international experts in the field, Avian Immunology 3rd, provides the most up-to-date crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. Avian Immunology, Third Edition, is a fascinating and growing field and surely provides new and exciting insights for mainstream immunology in the future. Reflects significant advances in the field since the second edition, particularly the explosion of knowledge on genomics including work on the chicken, turkey and zebra finch genomes Provides a single source reference ranging from the basic science to cutting edge research Provides practical information for veterinarians particularly those specialised in poultry or companion bird medicine New chapters on the impact of the microbiome on the immune system, defence mechanisms in the egg and embryo and emerging transgene technologies

Assessing the Environmental Adaptation of Wildlife and Production Animals

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Author :
Publisher : MDPI
ISBN 13 : 3036501428
Total Pages : 190 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Assessing the Environmental Adaptation of Wildlife and Production Animals by : Edward Narayan

Download or read book Assessing the Environmental Adaptation of Wildlife and Production Animals written by Edward Narayan and published by MDPI. This book was released on 2021-03-04 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wild animals under human care as well as domesticated farm production animals are often exposed to environmental changes (e.g., capture and transportation). Short-term or acute changes in physiological indices (e.g., heart rate, respiration, body temperatures, immune cells, and stress hormonal biomarkers) provide crucial information regarding the responses of animals to novel environments, and they could provide crucial determining factors for the long-term health and welfare of animals. This Special Issue includes experimental research papers that demonstrate the applications of physiological indices and welfare assessment methods (e.g., morphological and morphometric data, behavioural assessments, thermal profiles, and physiological markers) in any wildlife or production animal (e.g., rescued and rehabilitating animals, pets, competition animals, farm animals, and zoo animals), in response to environmental and management related factors. The goal is to provide examples of new research and techniques that can be used to monitor short- and long-term environmental adaptation of animals under human care.

Inauguration Symposium on Current Trends in Immunology and Genetics and Their Implications for Parasitic Diseases

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Author :
Publisher : ILRI (aka ILCA and ILRAD)
ISBN 13 :
Total Pages : 102 pages
Book Rating : 4./5 ( download)

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Book Synopsis Inauguration Symposium on Current Trends in Immunology and Genetics and Their Implications for Parasitic Diseases by :

Download or read book Inauguration Symposium on Current Trends in Immunology and Genetics and Their Implications for Parasitic Diseases written by and published by ILRI (aka ILCA and ILRAD). This book was released on with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Professional Sports Antitrust Immunity

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Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Professional Sports Antitrust Immunity by : United States. Congress. Senate. Committee on the Judiciary

Download or read book Professional Sports Antitrust Immunity written by United States. Congress. Senate. Committee on the Judiciary and published by . This book was released on 1983 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Symposium in Immunology V

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Publisher : Springer Science & Business Media
ISBN 13 : 3642798969
Total Pages : 182 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Symposium in Immunology V by : Martha M. Eibl

Download or read book Symposium in Immunology V written by Martha M. Eibl and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the most important papers presented at the 5th Symposium in Immunology, held April 7 - 8, 1995 in Strasbourg, France, are published. Theses papers are from leading experts in the fields covering topics ranging from basic mechanisms, such as the molecular anatomy of autoimmune diseases, to data relevant to the modern diagnosis, therapy, treatment, and prevention of viral infections. By collecting such a wide-range of papers the organizers of the meeting succeeded in compiling an integrated overview of current research, clinical studies, epidemiological data, and their interrelationship.

Immune responses to AAV vectors, from bench to bedside

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Publisher : Frontiers Media SA
ISBN 13 : 2889195007
Total Pages : 97 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Immune responses to AAV vectors, from bench to bedside by : Federico Mingozzi

Download or read book Immune responses to AAV vectors, from bench to bedside written by Federico Mingozzi and published by Frontiers Media SA. This book was released on 2015-06-30 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent wave of clinical studies demonstrating long-term therapeutic efficacy highlights the enormous potential of gene therapy as an approach to the treatment of inherited disorders and cancer. While in recent years lentiviral vectors have dominated the field of ex vivo gene therapy in man, adeno-associated virus (AAV) vectors have become the platform of choice for the in vivo gene delivery, both local and systemic. Despite the achievements in the clinic however, a number of hurdles remain to be overcome in gene therapy, these include availability of scalable vector production systems, potential issues associated with insertional mutagenesis, and concerns related to immunogenicity of gene therapeutics. For AAV vectors, clinical trials showed that immunity directed against the vector could either prevent transduction of a target tissue or limit the duration of therapeutic efficacy. Initial observations in the context of a gene therapy trial for hemophilia spurred over a decade efforts by gene therapists and immunologists to understand the mechanism and identify factors that contribute to AAV’s immunogenicity, including the prevalence of B cell and T cell immunity to wild type AAV in humans and the interaction of AAV vectors with the innate and adaptive immune system. Despite a number of important contributions in particular in the more recent past, our knowledge on the immunology of gene transfer is still rudimental; this is partly due to the fact that the basic understanding of the complex balance between tolerance and immunity to an antigen, key aspect of gene transfer with AAV, keeps evolving rapidly. However, continuing work towards a better definition of the interaction of viral vectors with the immune system has led to significant advances in the knowledge of the factors influencing the outcome of gene transfer, such as the vector dose, the immune privilege of certain tissues, and the induction of tolerance to an antigen. A better understanding of the structure-function relationship of the viral capsid has boosted the development of novel immune-escape vector variants. In addition, novel immunomodulatory strategies were established to prevent or reduce anti-capsid immunity have been developed and are being tested in preclinical models and in clinical trials. Together, these advances are bringing us closer to the goal of achieving safe and sustained therapeutic gene transfer in humans. In this research topic, a collection of Original Research and Review Articles highlights critical aspects of the interaction between gene AAV vectors and the immune system, discussing how these interactions can be either detrimental or constitute an advantage, depending on the context of gene transfer, and providing tools and resources to better understand the issue of immunogenicity of AAV vectors in gene transfer.

C-Type Lectin Receptors in Immunity

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Publisher : Springer
ISBN 13 : 4431560157
Total Pages : 215 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis C-Type Lectin Receptors in Immunity by : Sho Yamasaki

Download or read book C-Type Lectin Receptors in Immunity written by Sho Yamasaki and published by Springer. This book was released on 2016-03-22 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.

Prize Essays and Transactions

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Publisher :
ISBN 13 :
Total Pages : 594 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Prize Essays and Transactions by : Highland and agricultural society of Scotland, Edinburgh

Download or read book Prize Essays and Transactions written by Highland and agricultural society of Scotland, Edinburgh and published by . This book was released on 1902 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transactions

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Publisher :
ISBN 13 :
Total Pages : 598 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Transactions by : Royal Highland and Agricultural Society of Scotland

Download or read book Transactions written by Royal Highland and Agricultural Society of Scotland and published by . This book was released on 1902 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transactions of the Highland and Agricultural Society of Scotland

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Publisher :
ISBN 13 :
Total Pages : 596 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Transactions of the Highland and Agricultural Society of Scotland by : Royal Highland and Agricultural Society of Scotland

Download or read book Transactions of the Highland and Agricultural Society of Scotland written by Royal Highland and Agricultural Society of Scotland and published by . This book was released on 1902 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transactions of the Highland and Agricultural Society of Scotland

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Author :
Publisher :
ISBN 13 :
Total Pages : 594 pages
Book Rating : 4.1/5 (51 download)

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Book Synopsis Transactions of the Highland and Agricultural Society of Scotland by : Highland and Agricultural Society of Scotland

Download or read book Transactions of the Highland and Agricultural Society of Scotland written by Highland and Agricultural Society of Scotland and published by . This book was released on 1902 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunity to Listeria Monocytogenes

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Publisher : Academic Press
ISBN 13 : 0123947987
Total Pages : 202 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Immunity to Listeria Monocytogenes by :

Download or read book Immunity to Listeria Monocytogenes written by and published by Academic Press. This book was released on 2012-01-25 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contributions from leading authorities Informs and updates on all the latest developments in the field

Regulation of Immunity by Non-Immune Cells

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Publisher : Frontiers Media SA
ISBN 13 : 288971604X
Total Pages : 130 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Regulation of Immunity by Non-Immune Cells by : Kenji Kabashima

Download or read book Regulation of Immunity by Non-Immune Cells written by Kenji Kabashima and published by Frontiers Media SA. This book was released on 2021-11-08 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Insect Immunity

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Publisher : Academic Press
ISBN 13 : 0128117761
Total Pages : 262 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Insect Immunity by : Petros Ligoxygakis

Download or read book Insect Immunity written by Petros Ligoxygakis and published by Academic Press. This book was released on 2017-05-25 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insect Immunity, Volume 52 provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists and insect chemists. Presents a comprehensive overview of recent insect immunity science Written by leaders in their respective areas of research Ideal resource for invertebrate physiologists, neurobiologists, entomologists, zoologists and insect chemists