Vulnerabilities of the Global Supply Chains of Medicines

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Publisher :
ISBN 13 : 9789276581604
Total Pages : 0 pages
Book Rating : 4.5/5 (816 download)

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Book Synopsis Vulnerabilities of the Global Supply Chains of Medicines by :

Download or read book Vulnerabilities of the Global Supply Chains of Medicines written by and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The availability of medicines has been a longstanding concern in the EU. Throughout the last decade, the issue of medicines shortages has become systemic. Shortages of medicines affect treatment regimens. They may also affect the health of EU citizens and, ultimately, the resilience of health systems in Member States. The root causes of shortages are multifactorial, with challenges identified along the entire pharmaceutical value chain, from quality and manufacturing problems to industry's competitiveness. In particular, shortages of medicines can result from supply chain disruptions and vulnerabilities affecting the supply of key ingredients and components.

Pharmaceutical Supply Chains - Medicines Shortages

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Author :
Publisher : Springer
ISBN 13 : 3030153983
Total Pages : 269 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Pharmaceutical Supply Chains - Medicines Shortages by : Ana Paula Barbosa-Povoa

Download or read book Pharmaceutical Supply Chains - Medicines Shortages written by Ana Paula Barbosa-Povoa and published by Springer. This book was released on 2019-06-01 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insight of relevant case studies and updated practices in “PharmaceuticalSupply Chains” (PharmSC) while addressing the most relevant topics within the COST Action “Medicines Shortages” (CA15105).The volume focuses on the most recent developments in the design, planning and scheduling ofPharmSC, broadening from the suppliers’ selection to the impact on patients and healthcaresystems, addressing uncertainty and risk mitigation, and computational issues. It is directed at MSc/PhD students and young researchers (Post-Docs) in Pharmaceutics/Pharmaceutical sciences, Engineering fields, Economics/Management, as well as pharmaceutical decision makers, managers, and practitioners, and advanced readers demanding a fresh approach to decision making for PharmSC. The contributed chapters are associated with the homonymous COST Training Schools (TS), and the book creates a better understanding of the Action “Medicines Shortages” challenges and opportunities.

Threats to Pharmaceutical Supply Chains - Lessons Learned About Vulnerabilities from Hurricane Maria in Puerto Rico, Prioritizing the Pharmaceutical Industry Supply Chain as National Security Assets

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Publisher :
ISBN 13 : 9781071264867
Total Pages : 76 pages
Book Rating : 4.2/5 (648 download)

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Book Synopsis Threats to Pharmaceutical Supply Chains - Lessons Learned About Vulnerabilities from Hurricane Maria in Puerto Rico, Prioritizing the Pharmaceutical Industry Supply Chain as National Security Assets by : U S Government

Download or read book Threats to Pharmaceutical Supply Chains - Lessons Learned About Vulnerabilities from Hurricane Maria in Puerto Rico, Prioritizing the Pharmaceutical Industry Supply Chain as National Security Assets written by U S Government and published by . This book was released on 2019-06 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September 2017, Hurricane Maria caused severe devastation to the U.S. territory of Puerto Rico, which manufacturers nearly 10 percent of all drugs consumed by Americans. Given the large concentration of pharmaceutical manufacturing based in Puerto Rico, the destruction wrought by a Category 4 hurricane created shortages for specific medical products, which affected the standard of health care in the United States during an influenza epidemic throughout late 2017 and early 2018. The Analytic Exchange Program's (AEP's) team examining "Threats to Pharmaceutical Supply Chains" examines this event as a case study for the risks and implications of pharmaceutical supply chain disruption. What happened after Hurricane Maria could shed light on other supply chain vulnerabilities, including the effect of cyber-attacks against manufacturing infrastructure, geopolitical disputes affecting drug supply chain components, and the growing reliance on third party drug manufacturing and logistics suppliers. Awareness of vulnerabilities is the first step toward protecting the pharmaceutical supply chain as a component of critical infrastructure vital to U.S. national security interests. Our team recommends mitigating future supply chain disruption by increasing private sector and government coordination. This AEP team proposes several specific solutions policymakers and corporate executives should consider, including providing incentives for greater cooperation, prioritizing the U.S. pharmaceutical industry as a unique critical infrastructure component and national security asset, creating an industry-wide list of medications deemed "critical", and streamlining the approval process for backup medications and alternative sources of temporary production.This compilation includes a reproduction of the 2019 Worldwide Threat Assessment of the U.S. Intelligence Community. Executive Summary * Hurricane Maria and the Impact on the US Pharmaceutical Supply Chain: A Case Study * How Hurricane Maria Affected Pharmaceutical Manufacturing in Puerto Rico * Bad to Worse: Hurricane Maria and the US Flu Outbreak * Explaining Why Hurricane Maria Had Such an Impact * Beyond Our Case Study: Examining Risks and Hypothetical Scenarios * How Did We Get Here? Examining the Risks * Risk-based Hypothetical Scenarios * Observations and Recommendations * Goal: Expedite and Reinforce Manufacturer Disclosure of Drug Shortages to the FDA * Goal: Prioritize Disruptions to the Supply Chain or Manufacturing of Critical Drugs * Goal: Improving Incentives for Manufacturers to Maintain Supply * Goal: Prioritizing the Pharmaceutical Industry Supply Chain as National Security Assets * Concluding Remarks * Citations

The Impact of the Covid-19 Pandemic on Global Supply Chains

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Author :
Publisher : GRIN Verlag
ISBN 13 : 3346996379
Total Pages : 20 pages
Book Rating : 4.3/5 (469 download)

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Book Synopsis The Impact of the Covid-19 Pandemic on Global Supply Chains by : Chris Andersen

Download or read book The Impact of the Covid-19 Pandemic on Global Supply Chains written by Chris Andersen and published by GRIN Verlag. This book was released on 2024-01-17 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seminar paper from the year 2023 in the subject Business economics - Supply, Production, Logistics, grade: 5.0, Addis Ababa University, course: Master of Business Management, language: English, abstract: The COVID-19 pandemic profoundly disrupted global supply chains, leading to unprecedented economic challenges and logistical complexities. Originating in China in December 2019, the virus rapidly spread to over 210 countries, resulting in more than 100 million confirmed cases worldwide and over 2 million deaths. This global crisis triggered severe disruptions across various sectors, including high-tech industries, automotive manufacturing, pharmaceuticals, and food supply chains. Notably, companies like Apple, Samsung, and Tesla experienced production halts due to labor shortages and supply chain constraints. Additionally, the pharmaceutical industry grappled with increased demand for essential medical supplies, while the food sector faced labor shortages and transportation disruptions. The pandemic-induced shutdowns, travel restrictions, and stringent import/export controls severely hampered international logistics, further exacerbating supply chain vulnerabilities. Consequently, the crisis highlighted the intricate interdependencies within global supply chains and underscored the urgent need for resilience, sustainability, and strategic reevaluation to mitigate future disruptions effectively.

Biopharmaceutical Supply Chains

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Publisher : CRC Press
ISBN 13 : 1466568046
Total Pages : 275 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Biopharmaceutical Supply Chains by : Robert Handfield

Download or read book Biopharmaceutical Supply Chains written by Robert Handfield and published by CRC Press. This book was released on 2012-06-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive exploration of the massive changes in the biopharmaceutical supply chain that have occurred during the past 10 years, and predicted future trends, Biopharmaceutical Supply Chains: Distribution, Regulatory, Systems and Structural Changes Ahead documents the specific impacts of these changes for key players in the supply chain. Based

Drug Shortage Mitigation through Supply Chain Management

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Author :
Publisher : GRIN Verlag
ISBN 13 : 3656606366
Total Pages : 16 pages
Book Rating : 4.6/5 (566 download)

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Book Synopsis Drug Shortage Mitigation through Supply Chain Management by : Isabelle Köhler

Download or read book Drug Shortage Mitigation through Supply Chain Management written by Isabelle Köhler and published by GRIN Verlag. This book was released on 2014-03-03 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Essay from the year 2013 in the subject Business economics - Supply, Production, Logistics, grade: 1,0, San Diego State University, course: Global Supply Chain Management, language: English, abstract: The healthcare system of the U.S. is increasingly challenged by prescription drug shortages. But what are the root causes for this problem and how can these shortages be mitigated? Which role plays effective supply chain management in that setting? This paper addresses these questions and discusses possible approaches to strengthen the pharmaceutical supply chain in the U.S.

Pharmaceutical Supply Chains - Medicines Shortages

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Author :
Publisher :
ISBN 13 : 9783030153991
Total Pages : 256 pages
Book Rating : 4.1/5 (539 download)

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Book Synopsis Pharmaceutical Supply Chains - Medicines Shortages by : Ana Paula Barbosa-Povoa

Download or read book Pharmaceutical Supply Chains - Medicines Shortages written by Ana Paula Barbosa-Povoa and published by . This book was released on 2019 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insight of relevant case studies and updated practices in "Pharmaceutical Supply Chains" (PharmSC) while addressing the most relevant topics within the COST Action "Medicines Shortages" (CA15105). The volume focuses on the most recent developments in the design, planning and scheduling of PharmSC, broadening from the suppliers' selection to the impact on patients and healthcare systems, addressing uncertainty and risk mitigation, and computational issues. It is directed at MSc/PhD students and young researchers (Post-Docs) in Pharmaceutics/Pharmaceutical sciences, Engineering fields, Economics/Management, as well as pharmaceutical decision makers, managers, and practitioners, and advanced readers demanding a fresh approach to decision making for PharmSC. The contributed chapters are associated with the homonymous COST Training Schools (TS), and the book creates a better understanding of the Action "Medicines Shortages" challenges and opportunities.

Building Resilience Into the Nation?s Medical Product Supply Chains

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Author :
Publisher :
ISBN 13 : 9780309274692
Total Pages : pages
Book Rating : 4.2/5 (746 download)

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Book Synopsis Building Resilience Into the Nation?s Medical Product Supply Chains by : National Academies of Sciences Engineering and Medicine

Download or read book Building Resilience Into the Nation?s Medical Product Supply Chains written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-12-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, supply chain disruptions have repeatedly plagued the U.S. health care system, costing health care systems millions of dollars per year, threatening the clinical research enterprise, and most importantly, imperiling the health and lives of patients. The Committee on Security of America's Medical Supply Chain, convened by the National Academies of Sciences, Engineering, and Medicine, was charged with addressing this important issue by examining the root causes of medical product shortages and identifying ways to enhance their resilience - both in so-called normal times and during public health emergencies. Building Resilience into the Nation's Medical Product Supply Chains outlines the committee's seven recommendations and presents a framework of protection comprising awareness, mitigation, preparedness, and response measures.

Science-Based Approaches to Respond to COVID and Other Public Health Threats

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1839691433
Total Pages : 282 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Science-Based Approaches to Respond to COVID and Other Public Health Threats by : Erick Guerrero

Download or read book Science-Based Approaches to Respond to COVID and Other Public Health Threats written by Erick Guerrero and published by BoD – Books on Demand. This book was released on 2021-12-01 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: COVID-19 and other public health threats have contributed to more than six million deaths globally in a short amount of time. As such, there is an urgent need to respond to these threats in a way that improves global health and wellbeing. Written by a diverse group of exemplary scientists, the thirteen chapters in this volume provide unique, comprehensive, and science-based approaches to respond to macro-structural, human process, and micro issues affecting public health threats.

Global Supply Chains in the Pharmaceutical Industry

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Author :
Publisher : Business Science Reference
ISBN 13 : 9781522559238
Total Pages : 0 pages
Book Rating : 4.5/5 (592 download)

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Book Synopsis Global Supply Chains in the Pharmaceutical Industry by : Hamed Nozari

Download or read book Global Supply Chains in the Pharmaceutical Industry written by Hamed Nozari and published by Business Science Reference. This book was released on 2018-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book presents a complex view of supply chain management in global pharmaceutical industry, theory and empirical research findings. It also provides the resources necessary for policy makers and managers to adopt and implement supply chain in developing nations across the globe"--

Strengthening Post-Hurricane Supply Chain Resilience

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Author :
Publisher : National Academies Press
ISBN 13 : 0309494583
Total Pages : 137 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Strengthening Post-Hurricane Supply Chain Resilience by : National Academies of Sciences, Engineering, and Medicine

Download or read book Strengthening Post-Hurricane Supply Chain Resilience written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-04-02 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resilient supply chains are crucial to maintaining the consistent delivery of goods and services to the American people. The modern economy has made supply chains more interconnected than ever, while also expanding both their range and fragility. In the third quarter of 2017, Hurricanes Harvey, Irma and Maria revealed some significant vulnerabilities in the national and regional supply chains of Texas, Florida, the U.S. Virgin Islands, and Puerto Rico. The broad impacts and quick succession of these three hurricanes also shed light on the effectiveness of the nation's disaster logistics efforts during response through recovery. Drawing on lessons learned during the 2017 hurricanes, this report explores future strategies to improve supply chain management in disaster situations. This report makes recommendations to strengthen the roles of continuity planning, partnerships between civic leaders with small businesses, and infrastructure investment to ensure that essential supply chains will remain operational in the next major disaster. Focusing on the supply chains food, fuel, water, pharmaceutical, and medical supplies, the recommendations of this report will assist the Federal Emergency Management Agency as well as state and local officials, private sector decision makers, civic leaders, and others who can help ensure that supply chains remain robust and resilient in the face of natural disasters.

Pharmaceutical Supply Chain Resilience

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (131 download)

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Book Synopsis Pharmaceutical Supply Chain Resilience by : Emilia V. Yaroson

Download or read book Pharmaceutical Supply Chain Resilience written by Emilia V. Yaroson and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Countering the Problem of Falsified and Substandard Drugs

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Publisher : National Academies Press
ISBN 13 : 0309269393
Total Pages : 377 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Countering the Problem of Falsified and Substandard Drugs by : Institute of Medicine

Download or read book Countering the Problem of Falsified and Substandard Drugs written by Institute of Medicine and published by National Academies Press. This book was released on 2013-06-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adulteration and fraudulent manufacture of medicines is an old problem, vastly aggravated by modern manufacturing and trade. In the last decade, impotent antimicrobial drugs have compromised the treatment of many deadly diseases in poor countries. More recently, negligent production at a Massachusetts compounding pharmacy sickened hundreds of Americans. While the national drugs regulatory authority (hereafter, the regulatory authority) is responsible for the safety of a country's drug supply, no single country can entirely guarantee this today. The once common use of the term counterfeit to describe any drug that is not what it claims to be is at the heart of the argument. In a narrow, legal sense a counterfeit drug is one that infringes on a registered trademark. The lay meaning is much broader, including any drug made with intentional deceit. Some generic drug companies and civil society groups object to calling bad medicines counterfeit, seeing it as the deliberate conflation of public health and intellectual property concerns. Countering the Problem of Falsified and Substandard Drugs accepts the narrow meaning of counterfeit, and, because the nuances of trademark infringement must be dealt with by courts, case by case, the report does not discuss the problem of counterfeit medicines.

International Productivity Monitor

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Publisher : OECD Publishing
ISBN 13 : 9264279172
Total Pages : 222 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis International Productivity Monitor by : OECD

Download or read book International Productivity Monitor written by OECD and published by OECD Publishing. This book was released on 2017-07-17 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 32nd issue of the International Productivity Monitor is a special issue produced in collaboration with the OECD. All articles published in this issue were selected from papers presented at the First Annual Conference of the OECD Global Forum on Productivity held in Lisbon, Portugal, July ...

China Rx

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Publisher : Prometheus Books
ISBN 13 : 1633883817
Total Pages : 306 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis China Rx by : Rosemary Gibson

Download or read book China Rx written by Rosemary Gibson and published by Prometheus Books. This book was released on 2018 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans are taking prescription drugs made in China and don't know it-- and pharmaceutical companies are not eager to tell them. This probing book examines the implications for the quality and availability of vital medicines for consumers. Several decades ago, penicillin, vitamin C, and many other prescription and over-the-counter products were manufactured in the United States. But with the rise of globalization, antibiotics, antidepressants, birth control pills, blood pressure medicines, cancer drugs, among many others are made in China and sold in the United States. China's biggest impact on the US drug supply is making essential ingredients for thousands of medicines found in American homes and used in hospital intensive care units and operating rooms. The authors convincingly argue that there are at least two major problems with this scenario. First, it is inherently risky for the United States to become dependent on any one country as a source for vital medicines, especially given the uncertainties of geopolitics. For example, if an altercation in the South China Sea causes military personnel to be wounded, doctors may rely upon medicines with essential ingredients made by the adversary. Second, lapses in safety standards and quality control in Chinese manufacturing are a risk. Citing the concerns of FDA officials and insiders within the pharmaceutical industry, the authors document incidents of illness and death caused by contaminated medications that prompted reform. This is a disturbing, well-researched book and a wake-up call for improving the current system of drug supply and manufacturing.

Improving Global Health Supply Chains Through Traceability

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Improving Global Health Supply Chains Through Traceability by : Michael Pisa

Download or read book Improving Global Health Supply Chains Through Traceability written by Michael Pisa and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many low- and lower-middle-income countries (LMICs) where disease burdens are highest, health supply chains function poorly, resulting in frequent stockouts and a high prevalence of substandard and even falsified medications. In response to these concerns, the global health initiatives have stepped up their efforts to improve supply chain management. At the same time, a growing number of rich country pharmaceutical companies are investing in digital technologies that help them “track and trace” the movement of medicines through the supply chain at the package-level. Drawing from interviews with over thirty experts, we find that traceability offers a realistic solution to some of the problems found in LMIC health supply chains but that implementing the approach is a huge logistical endeavor that requires a strong political commitment. We close by discussing how donors can support committed governments, by taking an evidence-based approach to determine what traceability methods work best.

Impact of the Global Medical Supply Chain on SNS Operations and Communications

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Author :
Publisher : National Academies Press
ISBN 13 : 0309477778
Total Pages : 75 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Impact of the Global Medical Supply Chain on SNS Operations and Communications by : National Academies of Sciences, Engineering, and Medicine

Download or read book Impact of the Global Medical Supply Chain on SNS Operations and Communications written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-08-03 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Centers for Disease Control and Prevention (CDC) established the Strategic National Stockpile (SNS) with a focus on procuring and managing medical countermeasures (MCM) designed to address chemical, biological, radiological, and nuclear events and attacks by weapons of mass destruction. The stockpile is a repository of antibiotics, chemical antidotes, antitoxins, vaccines, antiviral drugs, and other medical materiel organized to respond to a spectrum of public health threats. Over time, the mission of the SNS has informally evolved to address other large-scale catastrophes, such as hurricanes or outbreaks of pandemic disease, and rare acute events, such as earthquakes or terror attacks. When disaster strikes, states can request deployment of SNS assets to augment resources available to state, local, tribal, or territorial public health agencies. CDC works with federal, state, and local health officials to identify and address their specific needs and, according to the stated mission of the SNS, ensure that the right resources reach the right place at the right time. On August 28, 2017, the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the current state of the global medical supply chain as it relates to SNS assets, and the role of communications in mitigating supply chain risks and in enhancing the resilience of MCM distribution efforts. This publication summarizes the presentations and discussions from the workshop.