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Validation Study Ii
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Book Synopsis Evolution of Translational Omics by : Institute of Medicine
Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Book Synopsis Test Development and Validation by : Gary Skaggs
Download or read book Test Development and Validation written by Gary Skaggs and published by SAGE Publications. This book was released on 2021-12-31 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Test Development and Validation by Gary Skaggs frameworks for test development and validation, and guidance for developing tests in straightforward language in one core text. Covering the changes in testing, technical development of tests and determining validity of tests, this book offers clear explanations within a real-world context.
Book Synopsis Expert System Verification and Validation Study by :
Download or read book Expert System Verification and Validation Study written by and published by . This book was released on 1991 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Validation Study of Two Self-concept and Two Attitude Towards School Instruments by : Trinidad N. Garcia
Download or read book A Validation Study of Two Self-concept and Two Attitude Towards School Instruments written by Trinidad N. Garcia and published by . This book was released on 1981 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Encyclopedia of Database Systems by : Ling Liu
Download or read book Encyclopedia of Database Systems written by Ling Liu and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis MINET Validation Study Using EBR-II Test Data by : Gregory J. Van Tuyle
Download or read book MINET Validation Study Using EBR-II Test Data written by Gregory J. Van Tuyle and published by . This book was released on 1983 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Basic Research in Crashworthiness II - Experimental Validation Study of the Analytical Predictive Techniques for the Large Deflection Dynamic Analysis of Plane Elasto-plastic Frame Structures. Interim Technical Report by : R. C. Shieh
Download or read book Basic Research in Crashworthiness II - Experimental Validation Study of the Analytical Predictive Techniques for the Large Deflection Dynamic Analysis of Plane Elasto-plastic Frame Structures. Interim Technical Report written by R. C. Shieh and published by . This book was released on 1973 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Finite Element Analysis by : Barna Szabó
Download or read book Finite Element Analysis written by Barna Szabó and published by John Wiley & Sons. This book was released on 2021-06-22 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finite Element Analysis An updated and comprehensive review of the theoretical foundation of the finite element method The revised and updated second edition of Finite Element Analysis: Method, Verification, and Validation offers a comprehensive review of the theoretical foundations of the finite element method and highlights the fundamentals of solution verification, validation, and uncertainty quantification. Written by noted experts on the topic, the book covers the theoretical fundamentals as well as the algorithmic structure of the finite element method. The text contains numerous examples and helpful exercises that clearly illustrate the techniques and procedures needed for accurate estimation of the quantities of interest. In addition, the authors describe the technical requirements for the formulation and application of design rules. Designed as an accessible resource, the book has a companion website that contains a solutions manual, PowerPoint slides for instructors, and a link to finite element software. This important text: Offers a comprehensive review of the theoretical foundations of the finite element method Puts the focus on the fundamentals of solution verification, validation, and uncertainty quantification Presents the techniques and procedures of quality assurance in numerical solutions of mathematical problems Contains numerous examples and exercises Written for students in mechanical and civil engineering, analysts seeking professional certification, and applied mathematicians, Finite Element Analysis: Method, Verification, and Validation, Second Edition includes the tools, concepts, techniques, and procedures that help with an understanding of finite element analysis.
Author :Agency for Healthcare Research and Quality/AHRQ Publisher :Government Printing Office ISBN 13 :1587634333 Total Pages :396 pages Book Rating :4.5/5 (876 download)
Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Author :University of Houston--Clear Lake. Research Institute for Computing and Information Systems Publisher : ISBN 13 : Total Pages :50 pages Book Rating :4.:/5 (363 download)
Book Synopsis Expert System Verification and Validation Study by : University of Houston--Clear Lake. Research Institute for Computing and Information Systems
Download or read book Expert System Verification and Validation Study written by University of Houston--Clear Lake. Research Institute for Computing and Information Systems and published by . This book was released on 1990 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Validation Study of Two Group Intelligence Tests by : Melvin Carl Schwartz
Download or read book A Validation Study of Two Group Intelligence Tests written by Melvin Carl Schwartz and published by . This book was released on 1964 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Validity and Validation by : Catherine S. Taylor
Download or read book Validity and Validation written by Catherine S. Taylor and published by Oxford University Press. This book was released on 2013-09-03 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Understanding Research series focuses on the process of writing up social research. The series is broken down into three categories: Understanding Statistics, Understanding Measurement, and Understanding Qualitative Research. The books provide researchers with guides to understanding, writing, and evaluating social research. Each volume demonstrates how research should be represented, including how to write up the methodology as well as the research findings. Each volume also reviews how to appropriately evaluate published research. Validity and Validation is an introduction to validity theory and to the methods used to obtain evidence for the validity of research and assessment results. The book pulls together the best thinking from educational and psychological research and assessment over the past 50 years. It briefly describes validity theory's roots in the philosophy of science. It highlights the ways these philosophical perspectives influence concepts of internal and external validity in research methodology, as well as concepts of validity and reliability in educational and psychological tests and measurements. Each chapter provides multiple examples (e.g., research designs and examples of output) to help the readers see how validation work is done in practice, from the ways we design research studies to the ways we interpret research results. Of particular importance is the practical focus on validation of scores from tests and other measures. The book also addresses strategies for investigating the validity of inferences we make about examinees using scores from assessments, as well as how to investigate score uses, the value implications of score interpretations, and the social consequences of score use. With this foundation, the book presents strategies for minimizing threats for validity as well as quantitative and qualitative methods for gathering evidence for the validity of scores.
Book Synopsis Animal Welfare Assessment, Volume II by : Edward Narayan
Download or read book Animal Welfare Assessment, Volume II written by Edward Narayan and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Police Validation Study by : John Clancy
Download or read book Police Validation Study written by John Clancy and published by . This book was released on 1974* with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Scale Development by : Robert F. DeVellis
Download or read book Scale Development written by Robert F. DeVellis and published by SAGE Publications. This book was released on 2016-03-30 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the Fourth Edition of Scale Development, Robert F. DeVellis demystifies measurement by emphasizing a logical rather than strictly mathematical understanding of concepts. The text supports readers in comprehending newer approaches to measurement, comparing them to classical approaches, and grasping more clearly the relative merits of each. This edition addresses new topics pertinent to modern measurement approaches and includes additional exercises and topics for class discussion. Available with Perusall—an eBook that makes it easier to prepare for class Perusall is an award-winning eBook platform featuring social annotation tools that allow students and instructors to collaboratively mark up and discuss their SAGE textbook. Backed by research and supported by technological innovations developed at Harvard University, this process of learning through collaborative annotation keeps your students engaged and makes teaching easier and more effective. Learn more.
Book Synopsis Validation of Score Meaning for the Next Generation of Assessments by : Kadriye Ercikan
Download or read book Validation of Score Meaning for the Next Generation of Assessments written by Kadriye Ercikan and published by Taylor & Francis. This book was released on 2017-03-27 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite developments in research and practice on using examinee response process data in assessment design, the use of such data in test validation is rare. Validation of Score Meaning in the Next Generation of Assessments Using Response Processes highlights the importance of validity evidence based on response processes and provides guidance to measurement researchers and practitioners in creating and using such evidence as a regular part of the assessment validation process. Response processes refer to approaches and behaviors of examinees when they interpret assessment situations and formulate and generate solutions as revealed through verbalizations, eye movements, response times, or computer clicks. Such response process data can provide information about the extent to which items and tasks engage examinees in the intended ways. With contributions from the top researchers in the field of assessment, this volume includes chapters that focus on methodological issues and on applications across multiple contexts of assessment interpretation and use. In Part I of this book, contributors discuss the framing of validity as an evidence-based argument for the interpretation of the meaning of test scores, the specifics of different methods of response process data collection and analysis, and the use of response process data relative to issues of validation as highlighted in the joint standards on testing. In Part II, chapter authors offer examples that illustrate the use of response process data in assessment validation. These cases are provided specifically to address issues related to the analysis and interpretation of performance on assessments of complex cognition, assessments designed to inform classroom learning and instruction, and assessments intended for students with varying cultural and linguistic backgrounds. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
