Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier

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Publisher : Frontiers Media SA
ISBN 13 : 2889453278
Total Pages : 185 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier by : Carlos P. Taborda

Download or read book Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier written by Carlos P. Taborda and published by Frontiers Media SA. This book was released on 2017-11-15 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. Also, it is growing the interest over new drugs development as second choice for treatment when traditional chemotherapy fail. This Research Topic will detail the exciting progress in developing vaccines, immunotherapy and new drugs for fungi.

Vaccines and immunotherapy against fungi: the new frontier

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Publisher : Frontiers E-books
ISBN 13 : 2889191168
Total Pages : 99 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Vaccines and immunotherapy against fungi: the new frontier by : Joshua D. Nosanchuk

Download or read book Vaccines and immunotherapy against fungi: the new frontier written by Joshua D. Nosanchuk and published by Frontiers E-books. This book was released on with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. This Research Topic will detail the exciting progress in developing vaccines and immunotherapy for fungi.

Antifungal and Antiparasitic Drug Delivery

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Publisher : MDPI
ISBN 13 : 3039363069
Total Pages : 168 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Antifungal and Antiparasitic Drug Delivery by : Juan José Torrado Durán

Download or read book Antifungal and Antiparasitic Drug Delivery written by Juan José Torrado Durán and published by MDPI. This book was released on 2020-07-01 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal and parasitic diseases affect more than one billion people across the globe. This is one-sixth of the world´s population, mostly located in developing countries. The lack of effective and safe treatments, combined with inefficient diagnosis, leads to serious chronic illness or even death. There is a discrepancy between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind the poor water solubility that limits their bioavailability and efficacy. There is an unmet clinical need to develop vaccines, novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effects by enhancing their dissolution, increasing their chemical potency, stabilizing the drug and targeting high concentrations of the drug to infection sites. This Special Issue includes ten research articles of antifungal and antiparasitic drug delivery systems.

Non-conventional Yeasts: from Basic Research to Application

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Publisher : Springer
ISBN 13 : 303021110X
Total Pages : 568 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Non-conventional Yeasts: from Basic Research to Application by : Andriy Sibirny

Download or read book Non-conventional Yeasts: from Basic Research to Application written by Andriy Sibirny and published by Springer. This book was released on 2019-08-12 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume scopes several aspects of non-conventional yeast research prepared by the leading specialists in the field. An introduction on taxonomy and systematics enhances the reader’s knowledge on yeasts beyond established ones such as Saccharomyces cerevisiae. Biotechnological approaches that involve fungal utilization of unusual substrates, production of biofuels and useful chemicals as citric acid, glutathione or erythritol are discussed. Further, strategies for metabolic engineering based on knowledge on regulation of gene expression as well as sensing and signaling pathways are presented. The book targets researchers and advanced students working in Microbiology, Microbial Biotechnology and Biochemistry.

Rang & Dale's Pharmacology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323873987
Total Pages : 1001 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Rang & Dale's Pharmacology E-Book by : James M. Ritter

Download or read book Rang & Dale's Pharmacology E-Book written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2023-05-13 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines Clear figures to aid understanding, including data figures as well as mechanistic diagrams, Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts Emphasis on therapeutic drugs to help apply theory to practice Over 150 questions and 12 clinical cases to test your knowledge New chapters on drugs and the eye and the pharmacological management of headache Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. A completely revised and updated chapter on lifestyle drugs Recent advances in oxygen sensing and response to reduced oxygen tension Expanded chapters on dementia and analgesic drugs

Rang & Dale's Pharmacology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323873987
Total Pages : 1001 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Rang & Dale's Pharmacology E-Book by : James M. Ritter

Download or read book Rang & Dale's Pharmacology E-Book written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2023-05-13 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines Clear figures to aid understanding, including data figures as well as mechanistic diagrams, Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts Emphasis on therapeutic drugs to help apply theory to practice Over 150 questions and 12 clinical cases to test your knowledge New chapters on drugs and the eye and the pharmacological management of headache Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. A completely revised and updated chapter on lifestyle drugs Recent advances in oxygen sensing and response to reduced oxygen tension Expanded chapters on dementia and analgesic drugs

The Fungal Cell Wall

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889661326
Total Pages : 167 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Fungal Cell Wall by : Fausto Almeida

Download or read book The Fungal Cell Wall written by Fausto Almeida and published by Frontiers Media SA. This book was released on 2020-11-19 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Textbook of Medical Mycology

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Publisher : JP Medical Ltd
ISBN 13 : 9386261839
Total Pages : 958 pages
Book Rating : 4.3/5 (862 download)

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Book Synopsis Textbook of Medical Mycology by : Jagdish Chander

Download or read book Textbook of Medical Mycology written by Jagdish Chander and published by JP Medical Ltd. This book was released on 2017-11-30 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical mycology refers to the study of fungi that produce disease in humans and other animals, and of the diseases they produce, their ecology, and their epidemiology. This new edition has been fully revised to provide microbiologists with the latest information on fungal infections, covering the entire spectrum of different types of infection, and therapeutic modalities. Beginning with a general overview explaining morphology, taxonomy, and diagnosis, the following sections cover the different categories of fungal infection including superficial cutaneous mycoses, subcutaneous mycoses, systemic mycoses and opportunistic mycoses. A complete section is dedicated to pseudofungal infections. The highly illustrated text concludes with a detailed appendices section and each chapter features key references for further reading. Key points Fully revised, fourth edition providing latest information on the diagnosis and management of fungal infections Covers the entire spectrum of mycoses Highly illustrated with clinical photographs and figures Previous edition (9788188039780) published in 2009

Antifungal Therapy

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Publisher : CRC Press
ISBN 13 : 0849387868
Total Pages : 484 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Antifungal Therapy by : Mahmoud Ghannoum

Download or read book Antifungal Therapy written by Mahmoud Ghannoum and published by CRC Press. This book was released on 2016-04-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2164 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Antifungal Drug Discovery: New Theories and New Therapies

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Publisher : Frontiers Media SA
ISBN 13 : 2889199509
Total Pages : 138 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Antifungal Drug Discovery: New Theories and New Therapies by : Chaminda Jayampath Seneviratne

Download or read book Antifungal Drug Discovery: New Theories and New Therapies written by Chaminda Jayampath Seneviratne and published by Frontiers Media SA. This book was released on 2016-09-13 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.

Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference by : Steven P. Templeton

Download or read book Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference written by Steven P. Templeton and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Worldwide emergence of drug-resistant fungi: From basic to clinic, volume II

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Publisher : Frontiers Media SA
ISBN 13 : 2832516483
Total Pages : 136 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Worldwide emergence of drug-resistant fungi: From basic to clinic, volume II by : Weihua Pan

Download or read book Worldwide emergence of drug-resistant fungi: From basic to clinic, volume II written by Weihua Pan and published by Frontiers Media SA. This book was released on 2023-04-17 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Translating tolerogenic therapies to the clinic – where do we stand and what are the barriers?

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Publisher : Frontiers E-books
ISBN 13 : 2889190994
Total Pages : 233 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Translating tolerogenic therapies to the clinic – where do we stand and what are the barriers? by : Stephen P. Cobbold

Download or read book Translating tolerogenic therapies to the clinic – where do we stand and what are the barriers? written by Stephen P. Cobbold and published by Frontiers E-books. This book was released on with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is a call for papers to provide an up to date assessment of current attempts to introduce tolerogenic therapies into clinical practice. Tolerance has been a highly sought after goal in the field of organ transplantation for over half a century, and is now readily achievable in rodent models, but considerable barriers remain to successfully translating tolerogenic treatments to the clinic. The initial call for this Research Topic has been aimed to provide an overview of recent advances made within the European RISET and American ITN networks with regard to tolerogenic strategies in clinical transplantation, autoimmune disease, and allergy. Articles will also cover the barriers to clinical tolerance induction and new emerging approaches to overcome such barriers. 1. Collaborative networks working towards the goal of therapeutic tolerance induction 2. Prope tolerance and minimization of immunosuppression 3. Lessons from operationally tolerant patients 4. Targeted withdrawal of immunosuppression 5. Stem cells and hematopoietic chimerism as a route to tolerance 6. Promoting regulatory T cells 7. Tolerogenic dendritic cells and negative vaccination 8. Inhibitory pathways and mechanisms in tolerance 9. Memory T cells and heterologous immunity 10. The innate response to allotransplants 11. Chronic graft loss--what are the missing links? 12. The impact of graft microenvironment on tolerance

Human Pathogenic Microbes

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Publisher : Academic Press
ISBN 13 : 032395426X
Total Pages : 292 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Human Pathogenic Microbes by : Manzoor Ahmad Mir

Download or read book Human Pathogenic Microbes written by Manzoor Ahmad Mir and published by Academic Press. This book was released on 2022-03-16 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considering the global emerging human pathogenic microbial diseases and trends, Human Pathogenic Microbes is framed to provide deep insights into the epidemic and emerging bacterial and fungal infections and diseases in humans. It presents novel, up-to-date, and cutting-edge knowledge regarding various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them. Human Pathogenic Microbes reflects the current research and development on the evolution of bacterial and fungal drug resistance: different bacterial and fungal antimicrobial drug resistance mechanisms along with their biological and molecular aspects. In a nutshell, Human Pathogenic Microbes describes a various bacterial and fungal diseases caused by different human pathogenic microbes employing different drug resistance mechanisms and processes. It also highlights the novel emerging approaches (Immunological and combinatorial) that will aid to fight against such bacterial and fungal pathogens. Provides a brief but thorough and recent knowledge of various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them Describes the different aspects of fungal, bacterial and antimicrobial resistance Addresses novel antimicrobial agents and approaches

Immunobiology of Carbohydrates

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306478444
Total Pages : 336 pages
Book Rating : 4.4/5 (784 download)

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Book Synopsis Immunobiology of Carbohydrates by : Simon Wong

Download or read book Immunobiology of Carbohydrates written by Simon Wong and published by Springer Science & Business Media. This book was released on 2003-10-31 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique in providing pertinent information on the various established roles carbohydrate play in the immune system and how the innate and adaptive immune systems respond to this type of microbial antigens. The editors selected only topics that have established basic and clinical relevance to this field. The topics from basic research are organised like a textbook, in order to guide the readers through complex sets of events that lead to clearance of or to immune responses toward carbohydrate antigens. The book is clear, concise and contains fully annotated summaries of the key basic and practical information on carbohydrate immunology from current literature. These topics are written by investigators from various disciplines (chemistry, medicine, biochemistry, glycobiology and immunology), creating a fine balance in the point of views presented in the book. It explores the challenges and rewards of understanding the importance of carbohydrates and glycoconjugates in health and disease, applying new knowledge from carbohydrate immunology in improving or developing novel sugar-based therapeutics, and vaccines and medicines. This book is most suitable for glycobiologists and immunologists, but many researchers whose interests, background and expertise are in any of the fifteen topics presented in this book will also find it appealing. It is also a valuable resource for postgraduate students, clinicians or anyone else who is curious about the role of carbohydrates in immunology, and would like to see the topics combined under one cover and in relation to each other.

Epitope Discovery and Synthetic Vaccine Design

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Publisher : Frontiers Media SA
ISBN 13 : 288945522X
Total Pages : 284 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Epitope Discovery and Synthetic Vaccine Design by : Clarisa Beatriz Palatnik-de-Sousa

Download or read book Epitope Discovery and Synthetic Vaccine Design written by Clarisa Beatriz Palatnik-de-Sousa and published by Frontiers Media SA. This book was released on 2018-07-12 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: