Immunity To Human Fungal Pathogens Mechanisms Of Host Recognition Protection Pathology And Fungal Interference

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Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference

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Author : Steven P. Templeton
Publisher : Frontiers Media SA
ISBN 13 : 288945682X
Total Pages : 440 pages
Book Rating : 4.8/5 (894 download)

Book Synopsis Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference by : Steven P. Templeton

Download or read book Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference written by Steven P. Templeton and published by Frontiers Media SA. This book was released on 2019-01-24 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergence of antifungal-resistant strains. It is therefore of interest to increase our understanding of host-pathogen interactions in order to facilitate the development of new therapies for individuals suffering from fungal infection and disease. These early interactions are shaped by an array of constituent and secreted factors that stimulate or inhibit host immune responses toward protective or detrimental immunity. Likewise, an array of preformed factors and tissue-resident cells provide early protection from fungal infection and provide extracellular signals that result in localized recruitment of inflammatory cells and determine the character of subsequent adaptive antifungal immunity. This Research Topic explores the host and fungal pathways that program innate and adaptive immunity and the immune cells, molecules, and regulatory pathways that comprise protective or detrimental responses to fungal exposure or infection. Over 200 authors contributed reviews, opinions, or original research focusing on antifungal immunity in humans and in experimental models. We believe that the results of these efforts provide a benchmark for further advances and improved antifungal therapies.

The Immune Response

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Author : Tak W. Mak
Publisher : Academic Press
ISBN 13 : 0080534481
Total Pages : 1216 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis The Immune Response by : Tak W. Mak

Download or read book The Immune Response written by Tak W. Mak and published by Academic Press. This book was released on 2005-11-11 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Current and thorough 30 chapter reference reviewed by luminaries in the field Unique ‘single voice' ensures consistency of definitions and concepts Comprehensive and elegant illustrations bring key concepts to life Provides historical context to allow fuller understanding of key issues Introductory chapters 1-4 serve as an ‘Immunology Primer' before topics are discussed in more detail

Nijkamp and Parnham's Principles of Immunopharmacology

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Author : Michael J. Parnham
Publisher : Springer Nature
ISBN 13 : 3030108112
Total Pages : 888 pages
Book Rating : 4.0/5 (31 download)

Book Synopsis Nijkamp and Parnham's Principles of Immunopharmacology by : Michael J. Parnham

Download or read book Nijkamp and Parnham's Principles of Immunopharmacology written by Michael J. Parnham and published by Springer Nature. This book was released on 2019-12-10 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Immunity to Fungal Infections: Insights from the Innate Immune Recognition and Antifungal Effector Mechanisms

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Author : Rodrigo Tinoco Figueiredo
Publisher : Frontiers Media SA
ISBN 13 : 2889713253
Total Pages : 109 pages
Book Rating : 4.8/5 (897 download)

Book Synopsis Immunity to Fungal Infections: Insights from the Innate Immune Recognition and Antifungal Effector Mechanisms by : Rodrigo Tinoco Figueiredo

Download or read book Immunity to Fungal Infections: Insights from the Innate Immune Recognition and Antifungal Effector Mechanisms written by Rodrigo Tinoco Figueiredo and published by Frontiers Media SA. This book was released on 2021-09-15 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Trends in Mycological Research

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Author : Ajar Nath Yadav
Publisher : Springer Nature
ISBN 13 : 3030606597
Total Pages : 503 pages
Book Rating : 4.0/5 (36 download)

Book Synopsis Recent Trends in Mycological Research by : Ajar Nath Yadav

Download or read book Recent Trends in Mycological Research written by Ajar Nath Yadav and published by Springer Nature. This book was released on 2021-02-04 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi range from being microscopic, single-celled yeasts to multicellular and heterotrophic in nature. Fungal communities have been found in vast ranges of environmental conditions. They can be associated with plants epiphytically, endophytically, or rhizospherically. Extreme environments represent unique ecosystems that harbor novel biodiversity of fungal communities. Interest in the exploration of fungal diversity has been spurred by the fact that fungi perform numerous functions integral in sustaining the biosphere, ranging from nutrient cycling to environmental detoxification, which involves processes like augmentation, supplementation, and recycling of plant nutrients - a particularly important process in sustainable agriculture. Fungal communities from natural and extreme habitats help promote plant growth, enhance crop yield, and enhance soil fertility via direct or indirect plant growth promoting (PGP) mechanisms of solubilization of phosphorus, potassium, and zinc, production of ammonia, hydrogen cyanides, phytohormones, Fe-chelating compounds, extracellular hydrolytic enzymes, and bioactive secondary metabolites. These PGP fungi could be used as biofertilizers, bioinoculants, and biocontrol agents in place of chemical fertilizers and pesticides in eco-friendly manners for sustainable agriculture and environments. Along with agricultural applications, medically important fungi play a significant role for human health. Fungal communities are useful for sustainable environments as they are used for bioremediation which is the use of microorganisms' metabolism to degrade waste contaminants (sewage, domestic, and industrial effluents) into non-toxic or less toxic materials by natural biological processes. Fungi could be used as mycoremediation for the future of environmental sustainability. Fungi and fungal products have the biochemical and ecological capability to degrade environmental organic chemicals and to decrease the risk associated with metals, semi-metals, and noble metals either by chemical modification or by manipulating chemical bioavailability. The two volumes of Recent Trends in Mycological Research aim to provide an understanding of fungal communities from diverse environmental habitats and their potential applications in agriculture, medical, environments and industry. The books are useful to scientists, researchers, and students involved in microbiology, biotechnology, agriculture, molecular biology, environmental biology and related subjects.

The Fungal Kingdom

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Author : Joseph Heitman
Publisher : John Wiley & Sons
ISBN 13 : 1555819583
Total Pages : 1136 pages
Book Rating : 4.5/5 (558 download)

Book Synopsis The Fungal Kingdom by : Joseph Heitman

Download or read book The Fungal Kingdom written by Joseph Heitman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.

Fungal Polysaccharides

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Author : Paul A. Sandford
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.:/5 (44 download)

Book Synopsis Fungal Polysaccharides by : Paul A. Sandford

Download or read book Fungal Polysaccharides written by Paul A. Sandford and published by . This book was released on 1980 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of The Cell

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Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Infectious Diseases in the Intensive Care Unit

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Author : Manish Soneja
Publisher : Springer Nature
ISBN 13 : 981154039X
Total Pages : 404 pages
Book Rating : 4.8/5 (115 download)

Book Synopsis Infectious Diseases in the Intensive Care Unit by : Manish Soneja

Download or read book Infectious Diseases in the Intensive Care Unit written by Manish Soneja and published by Springer Nature. This book was released on 2020-07-31 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections in intensive care is a very broad topic, and this book provides concise yet comprehensive coverage. It focuses on the appropriate and judicious use of microbiological, radiological and point-of-care tests in diagnostic work-ups and evidence-based management protocols. Moreover, it offers essential information on the diagnosis and management of commonly encountered infections in the intensive care unit, making it a handy ready-reference manual for intensivists.

Fungal Metabolites

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Author : Jean-Michel Mérillon
Publisher :
ISBN 13 : 9783319194561
Total Pages : pages
Book Rating : 4.1/5 (945 download)

Book Synopsis Fungal Metabolites by : Jean-Michel Mérillon

Download or read book Fungal Metabolites written by Jean-Michel Mérillon and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fungal Diseases

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Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921226X
Total Pages : 488 pages
Book Rating : 4.3/5 (92 download)

Book Synopsis Fungal Diseases by : Institute of Medicine

Download or read book Fungal Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-08 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal diseases have contributed to death and disability in humans, triggered global wildlife extinctions and population declines, devastated agricultural crops, and altered forest ecosystem dynamics. Despite the extensive influence of fungi on health and economic well-being, the threats posed by emerging fungal pathogens to life on Earth are often underappreciated and poorly understood. On December 14 and 15, 2010, the IOM's Forum on Microbial Threats hosted a public workshop to explore the scientific and policy dimensions associated with the causes and consequences of emerging fungal diseases.

Candida and Candidiasis

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Author : Richard A. Calderone
Publisher : American Society for Microbiology Press
ISBN 13 : 1555815391
Total Pages : 1293 pages
Book Rating : 4.5/5 (558 download)

Book Synopsis Candida and Candidiasis by : Richard A. Calderone

Download or read book Candida and Candidiasis written by Richard A. Calderone and published by American Society for Microbiology Press. This book was released on 2011-12-07 with total page 1293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. • Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis. • Reviews the latest basic and clinical research, focusing on findings in genome variability, host-pathogen interactions, antifungal resistance and drug discovery, and diagnostics to foster better understanding and treatment of candidiasis. • Examines recent discoveries that have shed light on morphogenesis and the cell cycle, including how new findings on host responses may have applications for the diagnosis of blood-borne candidiasis.

The Fungal Cell Wall

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Author : Jean-Paul Latgé
Publisher : Springer Nature
ISBN 13 : 3030499286
Total Pages : 369 pages
Book Rating : 4.0/5 (34 download)

Book Synopsis The Fungal Cell Wall by : Jean-Paul Latgé

Download or read book The Fungal Cell Wall written by Jean-Paul Latgé and published by Springer Nature. This book was released on 2020-08-12 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.

Immunology and Evolution of Infectious Disease

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Author : Steven A. Frank
Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)

Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank

Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

Fungal Pathology

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Author : J.W. Kronstad
Publisher : Springer Science & Business Media
ISBN 13 : 9401595461
Total Pages : 407 pages
Book Rating : 4.4/5 (15 download)

Book Synopsis Fungal Pathology by : J.W. Kronstad

Download or read book Fungal Pathology written by J.W. Kronstad and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together twelve chapters on fungal pathogens with the goal of presenting an overview of the current areas of activity and the common themes that pervade research on these important organisms. The timing of the book is appropriate because we have gained sufficient insight from molecular genetic analyses to begin to make some comparisons between different fungal pathogens and to discuss the key advances that have been made. The chapters provide a broad survey of the important topics in fungal pathogenesis including morphogenesis, virulence, avirulence, and signaling. The reader also will fmd clear discussions of parasitism, mutualism, symbiosis, evolution, phylogeny and ecology for those fungi where these issues are especially important. Finally, many of the chapters in this book illustrate the fact that we are on the verge of a revolution in our understanding of fungal pathogens because of the application of genomics to these organisms and their hosts. The fungi included in this book represent many of the most intensively investigated fungal pathogens of plants; in this regard, a chapter is also included for pathogens in the Phytophthora group, even though these organisms are no longer classified as fungi. It is appropriate to include Phytophthora for historical reasons and, in addition, the insights in terms of pathogenesis and host-specific interactions are important to keep in mind when considering fungal pathogens. Chapters are also included on pathogens of insects and humans, as well as endophytic fungi.

Fungal Plant Pathogens, 2nd Edition

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Author : Charles R. Lane
Publisher : CABI
ISBN 13 : 1800620551
Total Pages : 331 pages
Book Rating : 4.8/5 (6 download)

Book Synopsis Fungal Plant Pathogens, 2nd Edition by : Charles R. Lane

Download or read book Fungal Plant Pathogens, 2nd Edition written by Charles R. Lane and published by CABI. This book was released on 2023-07-30 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This substantially updated edition now in full colour provides key techniques used when working with fungal and fungal-like plant pathogens. As a practical manual it also deals with disease recognition, detection and identification of fungi, plus methods to characterise and curate fungi and handle them under quarantine and quality assurance systems. Fungal Plant Pathogens: Applied Techniques, 2nd edition provides a valuable guide to investigating fungal plant diseases and interpreting laboratory findings for postgraduate and advanced undergraduate students, extension plant pathologists, consultants and advisers in agriculture, forestry and horticulture, and the food supply chain.

Fungal Immunology:

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Author : Paul L. Fidel
Publisher : Springer Science & Business Media
ISBN 13 : 0387254455
Total Pages : 507 pages
Book Rating : 4.3/5 (872 download)

Book Synopsis Fungal Immunology: by : Paul L. Fidel

Download or read book Fungal Immunology: written by Paul L. Fidel and published by Springer Science & Business Media. This book was released on 2006-04-09 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.