Vaccines And Immunotherapy Against Fungi The New Frontier

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Vaccines and immunotherapy against fungi: the new frontier

Author : Joshua D. Nosanchuk
Publisher : Frontiers E-books
ISBN 13 : 2889191168
Total Pages : 99 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Vaccines and immunotherapy against fungi: the new frontier by : Joshua D. Nosanchuk

Download or read book Vaccines and immunotherapy against fungi: the new frontier written by Joshua D. Nosanchuk and published by Frontiers E-books. This book was released on with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. This Research Topic will detail the exciting progress in developing vaccines and immunotherapy for fungi.

Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier

Author : Carlos P. Taborda
Publisher : Frontiers Media SA
ISBN 13 : 2889453278
Total Pages : 185 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier by : Carlos P. Taborda

Download or read book Vaccines, Immunotherapy and New Antifungal Therapy Against Fungi: Updates in the New Frontier written by Carlos P. Taborda and published by Frontiers Media SA. This book was released on 2017-11-15 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. Also, it is growing the interest over new drugs development as second choice for treatment when traditional chemotherapy fail. This Research Topic will detail the exciting progress in developing vaccines, immunotherapy and new drugs for fungi.

Textbook of Medical Mycology

Author : Jagdish Chander
Publisher : JP Medical Ltd
ISBN 13 : 9386261839
Total Pages : 958 pages
Book Rating : 4.3/5 (862 download)

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Book Synopsis Textbook of Medical Mycology by : Jagdish Chander

Download or read book Textbook of Medical Mycology written by Jagdish Chander and published by JP Medical Ltd. This book was released on 2017-11-30 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical mycology refers to the study of fungi that produce disease in humans and other animals, and of the diseases they produce, their ecology, and their epidemiology. This new edition has been fully revised to provide microbiologists with the latest information on fungal infections, covering the entire spectrum of different types of infection, and therapeutic modalities. Beginning with a general overview explaining morphology, taxonomy, and diagnosis, the following sections cover the different categories of fungal infection including superficial cutaneous mycoses, subcutaneous mycoses, systemic mycoses and opportunistic mycoses. A complete section is dedicated to pseudofungal infections. The highly illustrated text concludes with a detailed appendices section and each chapter features key references for further reading. Key points Fully revised, fourth edition providing latest information on the diagnosis and management of fungal infections Covers the entire spectrum of mycoses Highly illustrated with clinical photographs and figures Previous edition (9788188039780) published in 2009

Antifungal and Antiparasitic Drug Delivery

Author : Juan José Torrado Durán
Publisher : MDPI
ISBN 13 : 3039363069
Total Pages : 168 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Antifungal and Antiparasitic Drug Delivery by : Juan José Torrado Durán

Download or read book Antifungal and Antiparasitic Drug Delivery written by Juan José Torrado Durán and published by MDPI. This book was released on 2020-07-01 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal and parasitic diseases affect more than one billion people across the globe. This is one-sixth of the world´s population, mostly located in developing countries. The lack of effective and safe treatments, combined with inefficient diagnosis, leads to serious chronic illness or even death. There is a discrepancy between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind the poor water solubility that limits their bioavailability and efficacy. There is an unmet clinical need to develop vaccines, novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effects by enhancing their dissolution, increasing their chemical potency, stabilizing the drug and targeting high concentrations of the drug to infection sites. This Special Issue includes ten research articles of antifungal and antiparasitic drug delivery systems.

Rang & Dale's Pharmacology E-Book

Author : James M. Ritter
Publisher : Elsevier Health Sciences
ISBN 13 : 0323873987
Total Pages : 1001 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Rang & Dale's Pharmacology E-Book by : James M. Ritter

Download or read book Rang & Dale's Pharmacology E-Book written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2023-05-13 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rang and Dale's Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. - Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines - Clear figures to aid understanding, including data figures as well as mechanistic diagrams, - Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts - Emphasis on therapeutic drugs to help apply theory to practice - Over 150 questions and 12 clinical cases to test your knowledge - New chapters on drugs and the eye and the pharmacological management of headache - Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. - A completely revised and updated chapter on lifestyle drugs - Recent advances in oxygen sensing and response to reduced oxygen tension - Expanded chapters on dementia and analgesic drugs

Non-conventional Yeasts: from Basic Research to Application

Author : Andriy Sibirny
Publisher : Springer
ISBN 13 : 303021110X
Total Pages : 566 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Non-conventional Yeasts: from Basic Research to Application by : Andriy Sibirny

Download or read book Non-conventional Yeasts: from Basic Research to Application written by Andriy Sibirny and published by Springer. This book was released on 2019-08-12 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume scopes several aspects of non-conventional yeast research prepared by the leading specialists in the field. An introduction on taxonomy and systematics enhances the reader’s knowledge on yeasts beyond established ones such as Saccharomyces cerevisiae. Biotechnological approaches that involve fungal utilization of unusual substrates, production of biofuels and useful chemicals as citric acid, glutathione or erythritol are discussed. Further, strategies for metabolic engineering based on knowledge on regulation of gene expression as well as sensing and signaling pathways are presented. The book targets researchers and advanced students working in Microbiology, Microbial Biotechnology and Biochemistry.

The Fungal Cell Wall

Author : Fausto Almeida
Publisher : Frontiers Media SA
ISBN 13 : 2889661326
Total Pages : 167 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Fungal Cell Wall by : Fausto Almeida

Download or read book The Fungal Cell Wall written by Fausto Almeida and published by Frontiers Media SA. This book was released on 2020-11-19 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Rang & Dale's Pharmacology E-Book

Author : James M. Ritter
Publisher : Elsevier Health Sciences
ISBN 13 : 0323873987
Total Pages : 1001 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Rang & Dale's Pharmacology E-Book by : James M. Ritter

Systemic Fungal Infections: Principles, Pathogenesis & Practice

Author : Monica Mahajan
Publisher : Jaypee Brothers Medical Publishers
ISBN 13 : 9389188342
Total Pages : 460 pages
Book Rating : 4.3/5 (891 download)

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Book Synopsis Systemic Fungal Infections: Principles, Pathogenesis & Practice by : Monica Mahajan

Download or read book Systemic Fungal Infections: Principles, Pathogenesis & Practice written by Monica Mahajan and published by Jaypee Brothers Medical Publishers. This book was released on 2019-08-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mucosal Vaccines

Author : Hiroshi Kiyono
Publisher : Elsevier
ISBN 13 : 0080537057
Total Pages : 501 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Mucosal Vaccines by : Hiroshi Kiyono

Download or read book Mucosal Vaccines written by Hiroshi Kiyono and published by Elsevier. This book was released on 1996-10-23 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. - Provides the latest views on mucosal vaccines - Applies basic principles to the development of new vaccines - Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases - Unique and user-friendly organization

Carbohydrate-based Vaccines

Author : René Roy
Publisher : ACS Symposium
ISBN 13 : 9780841239838
Total Pages : 0 pages
Book Rating : 4.2/5 (398 download)

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Book Synopsis Carbohydrate-based Vaccines by : René Roy

Download or read book Carbohydrate-based Vaccines written by René Roy and published by ACS Symposium. This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind entirely dedicated to carbohydrate vaccines written by renowned scientists with expertise in carbohydrate chemistry and immunochemistry. It covers the synthesis of carbohydrate antigens related to bacteria and parasites such as: Heamophilus influenza, Streptococcus pnemoniae, Shigella flexneri, Candida albicans, Mycobacterium tuberculosis, and Chlamydia. The first three chapters are of wide interest as they cover fundamental concerns in new vaccine developments. The first one presents the immune system and how carbohydrate antigens are processed before protective antibodies are produced. It also illustrates antigen presentation in the context of major histocompatibility complexes (MHCs). The second chapter describes regulatory issues when carbohydrate vaccines are involved while the third one discuss several techniques used in conjugation chemistry and the implication of certain chemical linkages that may induce unexpected anti-linker antibodies. This section will be particularly appealing for those involved in drug-conjugate design, pro-drug developments, and drug vectorization. The book concludes with one chapter that illustrates the principle through which peptide antigens can functionally mimic carbohydrate epitopes, thus, unraveling the potential for peptide surrogates as replacement for complex carbohydrate structures. This book is unique in that it covers all aspects related to carbohydrate vaccines including the success story with the first semi-synthetic bacterial polysaccharide vaccine against Heamophilus influenza type b responsible for pneumonia and meningitis, liable for more than 600,000 infant deaths worldwide in developing countries. The book also presents regulatory issues and will thus be vital for government agencies approving candidate vaccines. It widely covers synthetic methodologies for the attachment of carbohydrate antigens to peptides and immunogenic protein carriers. Vaccines against bacterial antigens, cancer, and parasites are also discussed by worldwide experts in this field in details. No other book contains such a wide panel of different expertise. It will also be useful to students and researchers involved with the immunology of forreings antigens and how the under appreciated carbohydrate antigens are processed by the immune system.

A Global Perspective on Vaccines: Priorities, Challenges and Online Information

Author : Luciana Leite
Publisher : Frontiers Media SA
ISBN 13 : 2889635333
Total Pages : 140 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis A Global Perspective on Vaccines: Priorities, Challenges and Online Information by : Luciana Leite

Download or read book A Global Perspective on Vaccines: Priorities, Challenges and Online Information written by Luciana Leite and published by Frontiers Media SA. This book was released on 2020-03-04 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Healthcare Materials

Author : Ashutosh Tiwari
Publisher : John Wiley & Sons
ISBN 13 : 1118773683
Total Pages : 421 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Advanced Healthcare Materials by : Ashutosh Tiwari

Download or read book Advanced Healthcare Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-05-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Human Viruses: Diseases, Treatments and Vaccines

Author : Shamim I. Ahmad
Publisher : Springer Nature
ISBN 13 : 303071165X
Total Pages : 745 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Human Viruses: Diseases, Treatments and Vaccines by : Shamim I. Ahmad

Download or read book Human Viruses: Diseases, Treatments and Vaccines written by Shamim I. Ahmad and published by Springer Nature. This book was released on 2021-05-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses current evidence on human viruses and provides an extensive coverage of newly emerged viruses and current strategies for treatment. Offering a new perspective in view of the re-emergence of Ebola in African countries and Dengue in India and Pakistan, the contents include chapters on emergence, pathogenicity, epidemiology and vaccine uptake. Human Viruses: Diseases, Treatments and Vaccines: The New Insights discusses a range of viruses from the most common such as Influenza and Hepatitis to Zika, Poliomyelitis and Chikungunya among many others. It is authored by a team of experts on viral disease and will be of immense use to virologists, public health experts and clinicians.

The Emperor of All Maladies

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Recent Advances in Drug Delivery Systems

Author : James M. Anderson
Publisher : Springer Science & Business Media
ISBN 13 : 1461327458
Total Pages : 391 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Recent Advances in Drug Delivery Systems by : James M. Anderson

Download or read book Recent Advances in Drug Delivery Systems written by James M. Anderson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evident rapid expansion of scientific work and intense interest in both experimental and clinical aspects of new drug delivery systems provided strong motivation for planning this symposium. In designing the program, speakers were identified for their particular expertise in a wide range of topics such as dermal delivery systems, pro-drugs, oral prolonged release, rate-controlled drug delivery, the pharmacokinetics of drug release systems, the synthesis of polymeric drug carriers and the refinement of drug delivery pumps. Because of the considerable involvement of diverse scientists from laboratories around the world where investigations relevant to the topic are now being pursued, a deliberate effort was made to invite international leaders in the field to share their knowledge and experimental outcomes. Thus, plenary papers and panel discussions were offered by organic chemists, bioengineers, patholo gists, material scientists, physical chemists, and pharmacokineti cists from academic and industrial laboratories in some dozen countries. This book which records the presentations offered at the sym posium covers a broad array of topics ranging from general overviews of the physicochemical concepts and analytical methodology which underpin the refinement of drug delivery systems and the tissue responses associated with the use of such systems through detailed discussions of a variety of current approaches employed in the development of new systems.

Virus-Like Particle Vaccines

Author : Martin F Bachmann
Publisher : Mdpi AG
ISBN 13 : 9783039430741
Total Pages : 262 pages
Book Rating : 4.4/5 (37 download)

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Book Synopsis Virus-Like Particle Vaccines by : Martin F Bachmann

Download or read book Virus-Like Particle Vaccines written by Martin F Bachmann and published by Mdpi AG. This book was released on 2020-09-16 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.