Understanding Toxicology

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Understanding Toxicology

Author : Steven Mercurio
Publisher : Jones & Bartlett Learning
ISBN 13 : 1284127613
Total Pages : 952 pages
Book Rating : 4.2/5 (841 download)

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Book Synopsis Understanding Toxicology by : Steven Mercurio

Download or read book Understanding Toxicology written by Steven Mercurio and published by Jones & Bartlett Learning. This book was released on 2016-08-30 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Toxicology is a comprehensive study of toxicants and their impact on all levels of biology--from cell, to complex organism, to ecosystem. Unlike other texts of its kind, this text is uniquely structured by biological system, making it easy for readers to understand the impact of toxins on each system. Common mechanisms are explored in the cellular and complex organ system chapters to approach a systems biology perspective that is more applicable to modern computational toxicology risk assessment. Understanding Toxicology begins with three research questions that challenge the reader to discover what information is needed to solve controversies at the level of the cell, the complex organism, and the ecosystem. The book continues with a cellular, complex organism, and ecosystem analysis of toxicology principles including risk assessment. The cellular section follows common mechanisms from the outside to the inside of cells and individual organelles. A forensic approach analyzes complex organisms from outside to inside. The ecosystem section starts with a dispersion approach to determine environmental concentration and addresses toxicants in divisions similar to how the EPA determines impacts. Key Features • Uses lively, engaging examples making the text fun and easy to read and understand • Allows the reader to approach the subject from a research perspective as well as a public policy perspective • Covers biological toxicants including venoms, poisons, as well as microbial and fungal toxins, and plant toxins • Thoroughly covers all organisms including fish, plants, and microbes • Includes outlines and review questions in each chapter

Understanding Toxicology

Author : H. Bruno Schiefer
Publisher : CRC Press
ISBN 13 : 9781439805640
Total Pages : 160 pages
Book Rating : 4.8/5 (56 download)

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Book Synopsis Understanding Toxicology by : H. Bruno Schiefer

Download or read book Understanding Toxicology written by H. Bruno Schiefer and published by CRC Press. This book was released on 1997-02-28 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in clear, simple language, this concise book introduces the lay person to the science of toxicology as it relates to daily living. The book provides a general overview of toxicology, presenting the facts and underlying principles needed by non-specialists for making decisions about potentially hazardous substances in everyday settings. Understanding Toxicology: Chemicals, Their Benefits and Risks will help you separate fact from fiction and better evaluate conflicting news reports on toxic substances and hazards. It's for everyone interested in chemical safety, toxic risks, pollution, hazardous wastes, and potential health hazards found in the home, at work, and in the environment.

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

Author : Ali S. Faqi
Publisher : Elsevier
ISBN 13 : 0323984622
Total Pages : 1074 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Nonclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Toxicology and Environmental Health Information Resources

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309175011
Total Pages : 172 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicology and Environmental Health Information Resources by : Institute of Medicine

Download or read book Toxicology and Environmental Health Information Resources written by Institute of Medicine and published by National Academies Press. This book was released on 1997-02-10 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The environment is increasingly recognized as having a powerful effect on human and ecological health, as well as on specific types of human morbidity, mortality, and disability. While the public relies heavily on federal and state regulatory agencies for protection from exposures to hazardous substances, it often looks to health professionals for information about routes of exposure and the nature and extent of associated adverse health consequences. However, most health professionals acquire only a minimal knowledge of toxicology during their education and training. In 1967 the National Library of Medicine (NLM) created an information resource, known today as the Toxicology and Environmental Health Information Program (TEHIP). In 1995 the NLM asked the Institute of Medicine to examine the accessiblity and utility of the TEHIP databases for the work of health professionals. This resulting volume contains chapters on TEHIP and other toxicology and environmental health databases, on understanding the toxicology and environmental health information needs of health professionals, on increasing awareness of information resources through training and outreach, on accessing and navigating the TEHIP databases, and on program issues and future directions.

An Introduction to Interdisciplinary Toxicology

Author : Carey N. Pope
Publisher : Academic Press
ISBN 13 : 0128136022
Total Pages : 644 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis An Introduction to Interdisciplinary Toxicology by : Carey N. Pope

Download or read book An Introduction to Interdisciplinary Toxicology written by Carey N. Pope and published by Academic Press. This book was released on 2020-03-06 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained

Concepts in Toxicology

Author : John H. Duffus
Publisher : Royal Society of Chemistry
ISBN 13 : 0854041575
Total Pages : 189 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Concepts in Toxicology by : John H. Duffus

Download or read book Concepts in Toxicology written by John H. Duffus and published by Royal Society of Chemistry. This book was released on 2009 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a reference for those who need to understand the fundamental toxicological concepts that underlie both the scientific development of the subject and its practical applicaton in regulation and management of chemical safety.

Reference Manual on Scientific Evidence

Author :
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Reference Manual on Scientific Evidence by :

Download or read book Reference Manual on Scientific Evidence written by and published by . This book was released on 1994 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding Toxicology

Author : H. Bruno Schiefer
Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.:/5 (119 download)

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Book Synopsis Understanding Toxicology by : H. Bruno Schiefer

Download or read book Understanding Toxicology written by H. Bruno Schiefer and published by . This book was released on 1997 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals of Toxicology

Author : PK Gupta
Publisher : Academic Press
ISBN 13 : 0128054034
Total Pages : 422 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Fundamentals of Toxicology by : PK Gupta

Download or read book Fundamentals of Toxicology written by PK Gupta and published by Academic Press. This book was released on 2016-08-26 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. Explains the essential concepts of toxicology in a clear fashion Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology Explores the history, foundations, and most recent concepts of toxicology Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

Principles of Toxicology

Author : Stephen M. Roberts
Publisher : John Wiley & Sons
ISBN 13 : 0470907916
Total Pages : 496 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Principles of Toxicology by : Stephen M. Roberts

Download or read book Principles of Toxicology written by Stephen M. Roberts and published by John Wiley & Sons. This book was released on 2015-01-12 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms

The Dose Makes the Poison

Author : M. Alice Ottoboni
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.:/5 (4 download)

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Book Synopsis The Dose Makes the Poison by : M. Alice Ottoboni

Download or read book The Dose Makes the Poison written by M. Alice Ottoboni and published by . This book was released on 1984 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Dose Makes the Poison A Plain-Language Guide to Toxicology Second Edition M. Alice Ottoboni Increasing media coverage of reports on the effects of chemicals, new recognition within government and industry of the need to protect against exposure, and other current issues are elevating the public's concern about the health effects of synthetic chemicals in our environment. Unfortunately, much of this concern is based more on sensational news reports and half-truths than on scientific facts. This second edition of a widely read and highly acclaimed work reviews and explains the facts of chemical dangers in a clear and understandable manner. It objectively discusses the factors determining whether chemicals in our air, food, and water are harmful or harmless, and puts the dose - response relationship of chemicals in proper perspective. Effects of chemicals encountered at home and at work are presented in layman's language to assure understanding without having to turn to other references. Thoughtful discussions of controversial issues help you to understand news media reports on toxicology, avoid the half-truths that lead to "poison paranoia," and make informed judgments about our use and control of chemicals. Extensively revised, the second edition is also reorganized to expedite access to specific information. All experimental and analytical methods are in one section, and references to the origins of toxicology and regulation of chemicals are in another separate section to improve ease of reading. In addition, coverage of subjects such as public distrust of science, epidemiology, reproductive toxicology, and risk have been expanded to provide a better understanding of the relationship of toxicology to current environmental problems. All aspects of exposure and its effects are reviewed, including How chemicals cause harm-toxicity, sensitization, corrosiveness, irritation, radioactivity, and other properties Routes of exposure-skin, inhalation, oral, and combinations Factors that influence degree of toxicity-species, age, sex, nutrition, state of health, presence of other chemicals, adaptation, and possibly, light Chemicals that cause cancer and birth defects Chapters on toxicity of chemicals address no-effect levels and thresholds, margins of safety, and bioaccumulation. You'll see how the effects of chemicals are studied and how health problems are traced to environmental causes. Also clarified are differences between actual risk and perceived risk of various chemicals. With the media presenting us daily with new findings on chemical risks, this book provides a welcome "antidote" to the confusion. The Dose Makes the Poison is an easy-to-read review of toxicology that has become "required reading" for scientists and managers throughout industry; public health officials; environmental scientists; industrial hygienists; hazardous waste workers ; and anyone who wishes to improve his or her understanding of toxic chemicals without taking the time to go back to school.

Understanding Toxicology

Author : Steven Mercurio
Publisher : Jones & Bartlett Learning
ISBN 13 : 9781284126525
Total Pages : 0 pages
Book Rating : 4.1/5 (265 download)

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Book Synopsis Understanding Toxicology by : Steven Mercurio

Download or read book Understanding Toxicology written by Steven Mercurio and published by Jones & Bartlett Learning. This book was released on 2016-08-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Toxicology is a comprehensive study of toxicants and their impact on all levels of biology--from cell, to complex organism, to ecosystem. Unlike other texts of its kind, this text is uniquely structured by biological system, making it easy for readers to understand the impact of toxins on each system. Common mechanisms are explored in the cellular and complex organ system chapters to approach a systems biology perspective that is more applicable to modern computational toxicology risk assessment. Understanding Toxicology begins with three research questions that challenge the reader to discover what information is needed to solve controversies at the level of the cell, the complex organism, and the ecosystem. The book continues with a cellular, complex organism, and ecosystem analysis of toxicology principles including risk assessment. The cellular section follows common mechanisms from the outside to the inside of cells and individual organelles. A forensic approach analyzes complex organisms from outside to inside. The ecosystem section starts with a dispersion approach to determine environmental concentration and addresses toxicants in divisions similar to how the EPA determines impacts. Key Features • Uses lively, engaging examples making the text fun and easy to read and understand • Allows the reader to approach the subject from a research perspective as well as a public policy perspective • Covers biological toxicants including venoms, poisons, as well as microbial and fungal toxins, and plant toxins • Thoroughly covers all organisms including fish, plants, and microbes • Includes outlines and review questions in each chapter

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309112982
Total Pages : 300 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment by : National Research Council

Download or read book Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2007-12-19 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

How Tobacco Smoke Causes Disease

Author :
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

A Practical Guide to Toxicology and Human Health Risk Assessment

Author : Laura Robinson
Publisher : John Wiley & Sons
ISBN 13 : 1118881907
Total Pages : 400 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis A Practical Guide to Toxicology and Human Health Risk Assessment by : Laura Robinson

Download or read book A Practical Guide to Toxicology and Human Health Risk Assessment written by Laura Robinson and published by John Wiley & Sons. This book was released on 2018-11-05 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author’s training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.

Toxicology and Risk Assessment

Author : Helmut Greim
Publisher : John Wiley & Sons
ISBN 13 : 1119135915
Total Pages : 838 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Toxicology and Risk Assessment by : Helmut Greim

Download or read book Toxicology and Risk Assessment written by Helmut Greim and published by John Wiley & Sons. This book was released on 2018-11-05 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.

Toxicology

Author : John Joseph Fenton
Publisher : CRC Press
ISBN 13 : 1420042068
Total Pages : 585 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Toxicology by : John Joseph Fenton

Download or read book Toxicology written by John Joseph Fenton and published by CRC Press. This book was released on 2001-10-10 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORY Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduat