Uncertainty In Pharmacology

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Uncertainty in Pharmacology

Author : Adam LaCaze
Publisher : Springer Nature
ISBN 13 : 3030291790
Total Pages : 470 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Uncertainty in Pharmacology by : Adam LaCaze

Download or read book Uncertainty in Pharmacology written by Adam LaCaze and published by Springer Nature. This book was released on 2020-02-20 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a wide range of topics concerning methodological, epistemological, and regulatory-ethical issues around pharmacology. The book focuses in particular on the diverse sources of uncertainty, the different kinds of uncertainty that there are, and the diverse ways in which these uncertainties are (or could be) addressed. Compared with the more basic sciences, such as chemistry or biology, pharmacology works across diverse observable levels of reality: although the first step in the causal chain leading to the therapeutic outcome takes place at the biochemical level, the end-effect is a clinically observable result—which is influenced not only by biological actions, but also psychological and social phenomena. Issues of causality and evidence must be treated with these specific aspects in mind. In covering these issues, the book opens up a common domain of investigation which intersects the deeply intertwined dimensions of pharmacological research, pharmaceutical regulation and the related economic environment. The book is a collective endeavour with in-depth contributions from experts in pharmacology, philosophy of medicine, statistics, scientific methodology, formal and social epistemology, working in constant dialogue across disciplinary boundaries.

Testing Treatments

Author : Imogen Evans
Publisher : Pinter & Martin Publishers
ISBN 13 : 1905177488
Total Pages : 204 pages
Book Rating : 4.9/5 (51 download)

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Book Synopsis Testing Treatments by : Imogen Evans

Download or read book Testing Treatments written by Imogen Evans and published by Pinter & Martin Publishers. This book was released on 2011 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a thought-provoking account of how medical treatments can be tested with unbiased or 'fair' trials and explains how patients can work with doctors to achieve this vital goal. It spans the gamut of therapy from mastectomy to thalidomide and explores a vast range of case studies.

Uncertainty in Medicine

Author : Paul K. J. Han
Publisher : Oxford University Press
ISBN 13 : 0190270586
Total Pages : 193 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Uncertainty in Medicine by : Paul K. J. Han

Download or read book Uncertainty in Medicine written by Paul K. J. Han and published by Oxford University Press. This book was released on 2021 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction : The Challenge of Uncertainty in Medicine -- The Nature and Etiology of Uncertainty -- The Anatomy of Uncertainty -- The Natural History of Uncertainty -- The Management of Uncertainty -- A Way Forward : Systematizing Uncertainty Tolerance.

Mapping Uncertainty in Medicne

Author : Avril Danczak
Publisher : Royal College of General Practitioners
ISBN 13 : 0850844185
Total Pages : 342 pages
Book Rating : 4.8/5 (58 download)

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Book Synopsis Mapping Uncertainty in Medicne by : Avril Danczak

Download or read book Mapping Uncertainty in Medicne written by Avril Danczak and published by Royal College of General Practitioners. This book was released on 2016-02-28 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uncertainty is the norm in medical practice, yet often gives rise to distress in clinicians, who fear they will make shameful or guilt inducing errors. This book offers a succinct method to clinicians for classifying uncertainty and finding the right skills to manage different types of uncertainty successfully. Every clinician experiences moments when 'they don't know what to do'. Modern medicine is increasingly complex and training has also become more complicated. The days of 'see one, do one, teach one' are over. Yet, both younger clinicians and senior practitioners describe uncertainty as one of the most challenging and stressful aspects of clinical work. If uncertainty is uncomfortable or threatening to individual practitioners, it also provides complex educational challenges. How can we learn to cope with uncertainty effectively ourselves? How can we teach others to understand and manage uncertainty? In this ground breaking book, the authors propose ways to cut through uncertainty, which is explored as an inevitable (and even desirable) component of clinical practice. A Map of Uncertainty in Medicine (MUM) is used to classify uncertainty and to define the skills that will help find a way though practical difficulties. It is always good to have your MUM with you in a tricky situation!

The Good Doctor

Author : Kenneth Brigham
Publisher : Seven Stories Press
ISBN 13 : 1609809971
Total Pages : 178 pages
Book Rating : 4.6/5 (98 download)

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Book Synopsis The Good Doctor by : Kenneth Brigham

Download or read book The Good Doctor written by Kenneth Brigham and published by Seven Stories Press. This book was released on 2020-07-07 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: What makes a good doctor? It's not what you think. A doctor willing to face their own uncertainty in the face of illness and treatment might just be the best medicine. Too often we choose the wrong doctor for the wrong reasons. It doesn't have to be that way. In The Good Doctor, Ken Brigham, MD, and Michael M.E. Johns, MD, argue that we need to change the way we think about health care if we want to be the healthiest we can be. Counterintuitive as it may seem, uncertainty is integral to medicine, and you want a doctor who knows that: someone who sees you as the unique case you are, someone who knows that data isn't everything, someone who is able to change her mind as the information changes. For too long we've clung to the myth of the infallible doctor--one who assuredly tells us this is what's wrong and here is how I will cure you--and our health has suffered for it. Brigham and Johns propose a new model of medicine, one that is comfortable with ambiguity and that centers on an equal partnership between patient and doctor. Uncertainty, properly embraced, opens a new universe of possibilities.

Characterizing and Communicating Uncertainty in the Assessment of Benefits and Risks of Pharmaceutical Products

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309310032
Total Pages : 150 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Characterizing and Communicating Uncertainty in the Assessment of Benefits and Risks of Pharmaceutical Products by : Institute of Medicine

Download or read book Characterizing and Communicating Uncertainty in the Assessment of Benefits and Risks of Pharmaceutical Products written by Institute of Medicine and published by National Academies Press. This book was released on 2014-12-19 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the extensive body of evidence that informs regulatory decisions on pharmaceutical products, significant uncertainties persist, including the underlying variability in human biology, factors associated with the chemistry of a drug, and limitations in the research and clinical trial process itself that might limit the generalizability of results. As a result, regulatory reviewers are consistently required to draw conclusions about a drug's safety and efficacy from imperfect data. Efforts are underway within the drug development community to enhance the evaluation and communication of the benefits and risks associated with pharmaceutical products, aimed at increasing the predictability, transparency, and efficiency of pharmaceutical regulatory decision making. Effectively communicating regulatory decisions necessarily includes explanation of the impact of uncertainty on decision making. On February 12 and May 12, 2014, the Institute of Medicine's Forum on Drug Discovery, Development, and Translation held public workshops to advance the development of more systematic and structured approaches to characterize and communicate the sources of uncertainty in the assessment of benefits and risks, and to consider their implications for pharmaceutical regulatory decisions. Workshop presentations and discussions on February 12 were convened to explore the science of identifying and characterizing uncertainty in scientific evidence and approaches to translate uncertainties into decisions that reflect the values of stakeholders. The May 12 workshop presentations and discussions explored tools and approaches to communicating about scientific uncertainties to a range of stakeholders in the drug development process. Characterizing and Communicating Uncertainty in the Assessment of Benefits and Risks of Pharmaceutical Products summarizes the presentation and discussion of both events. This report explores potential analytical and communication approaches and identifies key considerations on their development, evaluation, and incorporation into pharmaceutical benefit- risk assessment throughout the entire drug development lifecycle.

Snowball in a Blizzard

Author : Steven Hatch
Publisher : Basic Books
ISBN 13 : 0465098576
Total Pages : 312 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Snowball in a Blizzard by : Steven Hatch

Download or read book Snowball in a Blizzard written by Steven Hatch and published by Basic Books. This book was released on 2016-02-23 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: There’s a running joke among radiologists: finding a tumor in a mammogram is akin to finding a snowball in a blizzard. A bit of medical gallows humor, this simile illustrates the difficulties of finding signals (the snowball) against a background of noise (the blizzard). Doctors are faced with similar difficulties every day when sifting through piles of data from blood tests to X-rays to endless lists of patient symptoms. Diagnoses are often just educated guesses, and prognoses less certain still. There is a significant amount of uncertainty in the daily practice of medicine, resulting in confusion and potentially deadly complications. Dr. Steven Hatch argues that instead of ignoring this uncertainty, we should embrace it. By digging deeply into a number of rancorous controversies, from breast cancer screening to blood pressure management, Hatch shows us how medicine can fail—sometimes spectacularly—when patients and doctors alike place too much faith in modern medical technology. The key to good health might lie in the ability to recognize the hype created by so many medical reports, sense when to push a physician for more testing, or resist a physician’s enthusiasm when unnecessary tests or treatments are being offered. Both humbling and empowering, Snowball in a Blizzard lays bare the inescapable murkiness that permeates the theory and practice of modern medicine. Essential reading for physicians and patients alike, this book shows how, by recognizing rather than denying that uncertainty, we can all make better health decisions.

The Tincture of Time

Author : Elizabeth L. Silver
Publisher : Penguin
ISBN 13 : 1101981458
Total Pages : 289 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis The Tincture of Time by : Elizabeth L. Silver

Download or read book The Tincture of Time written by Elizabeth L. Silver and published by Penguin. This book was released on 2018-04-24 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Set against the unexplained stroke of the author’s newborn daughter, this stunning, unflinchingly honest memoir is a thought-provoking reflection on uncertainty in medicine and in life. Growing up as the daughter of a dedicated surgeon, Elizabeth L. Silver felt an unquestioned faith in medicine. When her six-week-old daughter, Abby, was rushed to the Neonatal Intensive Care Unit with sudden seizures, and scans revealed a serious brain bleed, her relationship to medicine began to change. The Tincture of Time is Silver’s gorgeous and haunting chronicle of Abby’s first year. It’s a year of unending tests, doctors’ opinions, sleepless nights, promising signs and steps backward, and above all, uncertainty: The mysterious circumstances of Abby’s hospitalization attract dozens of specialists, none of whom can offer a conclusive answer about what went wrong or what the future holds. As Silver explores what it means to cope with uncertainty as a patient and parent and seeks peace in the reality that Abby’s injury may never be fully understood, she looks beyond her own story for comfort, probing literature and religion, examining the practice of medicine throughout history, and reporting the experiences of doctors, patients, and fellow caretakers. The result is a brilliant blend of personal narrative and cultural analysis, at once a poignant snapshot of a parent’s struggle and a wise meditation on the reality of uncertainty, in and out of medicine, and the hard-won truth that time is often its only cure. Heart-wrenching, unflinchingly honest, and beautifully written, The Tincture of Time is a powerful story of parenthood, an astute examination of the boundaries of medicine, and an inspiring reminder of life’s precariousness.

The Ethics of Uncertainty

Author : L. Syd M. Johnson
Publisher : Oxford University Press
ISBN 13 : 0190943645
Total Pages : 305 pages
Book Rating : 4.1/5 (99 download)

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Book Synopsis The Ethics of Uncertainty by : L. Syd M. Johnson

Download or read book The Ethics of Uncertainty written by L. Syd M. Johnson and published by Oxford University Press. This book was released on 2022 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Consciousness isn't a thing you can poke a stick at. It's not a natural kind, like a bit of quartz, or quarks, or water. Like "life," which can be attributed to many entities, but is not a thing with reality apart from living entities, consciousness can be attributed to conscious entities without being some further thing or fact, some mysterious, mentalizing "force" that can exist without conscious entities. It is manifested in conscious states and creatures, but isn't a thing in and of itself. One of the enduring puzzles about consciousness and conscious states is how they, as apparently mental, nonphysical states, can manifest in a physical entity like a brain. We can point to a physical bit of brain, to a neuron, or a structure like the thalamus, but we can't locate the consciousness within that bit of brain or its neural cells"--

The Handbook of Applied Communication Research

Author : H. Dan O'Hair
Publisher : John Wiley & Sons
ISBN 13 : 1119399874
Total Pages : 1100 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis The Handbook of Applied Communication Research by : H. Dan O'Hair

Download or read book The Handbook of Applied Communication Research written by H. Dan O'Hair and published by John Wiley & Sons. This book was released on 2020-04-24 with total page 1100 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative survey of different contexts, methodologies, and theories of applied communication The field of Applied Communication Research (ACR) has made substantial progress over the past five decades in studying communication problems, and in making contributions to help solve them. Changes in society, human relationships, climate and the environment, and digital media have presented myriad contexts in which to apply communication theory. The Handbook of Applied Communication Research addresses a wide array of contemporary communication issues, their research implications in various contexts, and the challenges and opportunities for using communication to manage problems. This innovative work brings together the diverse perspectives of a team of notable international scholars from across disciplines. The Handbook of Applied Communication Research includes discussion and analysis spread across two comprehensive volumes. Volume one introduces ACR, explores what is possible in the field, and examines theoretical perspectives, organizational communication, risk and crisis communication, and media, data, design, and technology. The second volume focuses on real-world communication topics such as health and education communication, legal, ethical, and policy issues, and volunteerism, social justice, and communication activism. Each chapter addresses a specific issue or concern, and discusses the choices faced by participants in the communication process. This important contribution to communication research: Explores how various communication contexts are best approached Addresses balancing scientific findings with social and cultural issues Discusses how and to what extent media can mitigate the effects of adverse events Features original findings from ongoing research programs and original communication models and frameworks Presents the best available research and insights on where current research and best practices should move in the future A major addition to the body of knowledge in the field, The Handbook of Applied Communication Research is an invaluable work for advanced undergraduate students, graduate students, and scholars.

Uncertainty

Author : Kostas Kampourakis
Publisher : Oxford University Press
ISBN 13 : 0190871687
Total Pages : 273 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Uncertainty by : Kostas Kampourakis

Download or read book Uncertainty written by Kostas Kampourakis and published by Oxford University Press. This book was released on 2019-10-07 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific knowledge is the most solid and robust kind of knowledge that humans have because of the self-correcting character inherent in its own processes. Nevertheless, anti-evolutionists, climate denialists, and anti-vaxxers, among others, question some of the best-established scientific findings, making claims that are unsupported by empirical evidence. A common aspect of these claims is the reference to the uncertainties in these areas of research, which leads to the conclusion that science is uncertain about evolution, climate change, and vaccination, among others. The truth of the matter is that while the broad picture is clear, there exist--and will always exist--uncertainties about the details of the respective phenomena. In this book Kampourakis and McCain show that uncertainty is an inherent feature of science that does not devalue it. In contrast, uncertainty actually makes science advance because it motivates further research. The first book of its kind, Uncertainty draws on philosophy of science to explain what uncertainty in science is and how it makes science advance. It contrasts evolution, climate change, and vaccination, where the uncertainties are exaggerated, to genetic testing and forensic science where the uncertainties are usually overlooked. Kampourakis and McCain discuss the scientific, psychological, and philosophical aspects of uncertainty in order to explain what it is really about, what kind of problems it actually poses, and why it ultimately makes science advance. Contrary to the public representations of scientific findings and conclusions that produce an intuitive but distorted view of science as certain, we need to understand and learn to live with uncertainty in science.

Improving and Accelerating Therapeutic Development for Nervous System Disorders

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309292492
Total Pages : 118 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine

Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Understanding Uncertainty

Author : Dennis V. Lindley
Publisher : John Wiley & Sons
ISBN 13 : 0470055472
Total Pages : 268 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Understanding Uncertainty by : Dennis V. Lindley

Download or read book Understanding Uncertainty written by Dennis V. Lindley and published by John Wiley & Sons. This book was released on 2006-08-28 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: A lively and informal introduction to the role of uncertainty and probability in people's lives from an everyday perspective From television game shows and gambling techniques to weather forecasting and the financial markets, virtually every aspect of modern life involves situations in which the outcomes are uncertain and of varying qualities. But as noted statistician Dennis Lindley writes in this distinctive text, "We want you to face up to uncertainty, not hide it away under false concepts, but to understand it and, moreover, to use the recent discoveries so that you can act in the face of uncertainty more sensibly than would have been possible without the skill." Accessibly written at an elementary level, this outstanding text examines uncertainty in various everyday situations and introduces readers to three rules--craftily laid out in the book--that prove uncertainty can be handled with as much confidence as ordinary logic. Combining a concept of utility with probability, the book insightfully demonstrates how uncertainty can be measured and used in everyday life, especially in decision-making and science. With a focus on understanding and using probability calculations, Understanding Uncertainty demystifies probability and: * Explains in straightforward detail the logic of uncertainty, its truths, and its falsehoods * Explores what has been learned in the twentieth century about uncertainty * Provides a logical, sensible method for acting in the face of uncertainty * Presents vignettes of great discoveries made in the twentieth century * Shows readers how to discern if another person--whether a lawyer, politician, scientist, or journalist--is talking sense, posing the right questions, or obtaining sound answers Requiring only a basic understanding of mathematical concepts and operations, Understanding Uncertainty is useful as a text for all students who have probability or statistics as part of their course, even at the most introductory level.

The Laws of Medicine

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 147678485X
Total Pages : 96 pages
Book Rating : 4.4/5 (767 download)

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Book Synopsis The Laws of Medicine by : Siddhartha Mukherjee

Download or read book The Laws of Medicine written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2015-10-13 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Error and Uncertainty in Diagnostic Radiology

Author : Michael A. Bruno
Publisher : Oxford University Press
ISBN 13 : 0190665416
Total Pages : 304 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Error and Uncertainty in Diagnostic Radiology by : Michael A. Bruno

Download or read book Error and Uncertainty in Diagnostic Radiology written by Michael A. Bruno and published by Oxford University Press. This book was released on 2018-02-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, radiological imaging tests - including CT scanning, MRI, PET, X-rays, ultrasound, fluoroscopy and other modalities - have become essential to the routine diagnostic process. While these modern advanced medical images and their striking anatomic detail have discovered underlying issues, they have also contributed to a false impression of infallibility. Unlike other straightforward diagnostic tests, such as the EKG or blood chemistry panel, radiological imaging tests are highly variable and complex, often yielding uncertain results, as well as frequent false-negatives and false-positives. The experts who interpret the images (the diagnostic radiologists) sometimes make mistakes: the practice of diagnostic radiology is a fallible, human endeavour, one involving complex perceptual, neuro-physiological and cognitive processes employed under a wide range of circumstances, and with a great deal of variability. Error and Uncertainty in Diagnostic Radiology opens the 'black box,' of medical imaging, exposing the remarkable inner workings of the process of diagnostic radiology-including how and why it can sometimes go tragically wrong. The occurrence of radiological error is shown to be fundamentally intertwined with the underlying high level of uncertainty known to be present in the diagnostic process. As a foremost expert on radiology quality and safety, Dr. Bruno provides insight into the various types of radiologist error, along with a conceptual framework for understanding error and uncertainty in radiology, leading to practical strategies for error prevention and for reducing the risk of harm to patients when errors inevitably occur. This book is essential for radiologists, members of the Society to Improve Diagnosis in Medicine, emergency physicians, medical educators, medical and hospice administrators, especially quality and safety officers, as well as malpractice insurance carriers.

Bodies in Flux

Author : Christa Teston
Publisher : University of Chicago Press
ISBN 13 : 022645083X
Total Pages : 254 pages
Book Rating : 4.2/5 (264 download)

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Book Synopsis Bodies in Flux by : Christa Teston

Download or read book Bodies in Flux written by Christa Teston and published by University of Chicago Press. This book was released on 2017-05-05 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doctors, scientists, and patients have long grappled with the dubious nature of “certainty” in medical practice. To help navigate the chaos caused by ongoing bodily change we rely on scientific reductions and deductions. We take what we know now and make best guesses about what will be. But bodies in flux always outpace the human gaze. Particularly in cancer care, processes deep within our bodies are at work long before we even know where to look. In the face of constant biological and technological change, how do medical professionals ultimately make decisions about care? Bodies in Flux explores the inventive ways humans and nonhumans work together to manufacture medical evidence. Each chapter draws on rhetorical theory to investigate a specific scientific method for negotiating medical uncertainty in cancer care, including evidential visualization, assessment, synthesis, and computation. Case studies unveil how doctors rely on visuals when deliberating about a patient’s treatment options, how members of the FDA use inferential statistics to predict a drug’s effectiveness, how researchers synthesize hundreds of clinical trials into a single evidence-based recommendation, and how genetic testing companies compute and commoditize human health. Teston concludes by advocating for an ethic of care that pushes back against the fetishization of certainty—an ethic of care that honors human fragility and bodily flux.

Clinical Reasoning: Knowledge, Uncertainty, and Values in Health Care

Author : Daniele Chiffi
Publisher : Springer Nature
ISBN 13 : 3030590941
Total Pages : 168 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Clinical Reasoning: Knowledge, Uncertainty, and Values in Health Care by : Daniele Chiffi

Download or read book Clinical Reasoning: Knowledge, Uncertainty, and Values in Health Care written by Daniele Chiffi and published by Springer Nature. This book was released on 2020 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a philosophically-based, yet clinically-oriented perspective on current medical reasoning aiming at 1) identifying important forms of uncertainty permeating current clinical reasoning and practice 2) promoting the application of an abductive methodology in the health context in order to deal with those clinical uncertainties 3) bridging the gap between biomedical knowledge, clinical practice, and research and values in both clinical and philosophical literature. With a clear philosophical emphasis, the book investigates themes lying at the border between several disciplines, such as medicine, nursing, logic, epistemology, and philosophy of science; but also ethics, epidemiology, and statistics. At the same time, it critically discusses and compares several professional approaches to clinical practice such as the one of medical doctors, nurses and other clinical practitioners, showing the need for developing a unified framework of reasoning, which merges methods and resources from many different clinical but also non-clinical disciplines. In particular, this book shows how to leverage nursing knowledge and practice, which has been considerably neglected so far, to further shape the interdisciplinary nature of clinical reasoning. Furthermore, a thorough philosophical investigation on the values involved in health care is provided, based on both the clinical and philosophical literature. The book concludes by proposing an integrative approach to health and disease going beyond the so-called "classical biomedical model of care".