Ultrastructure Of The Connective Tissue Matrix

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Ultrastructure of the Connective Tissue Matrix

Author : P. Motta
Publisher : Springer Science & Business Media
ISBN 13 : 1461328314
Total Pages : 224 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Ultrastructure of the Connective Tissue Matrix by : P. Motta

Download or read book Ultrastructure of the Connective Tissue Matrix written by P. Motta and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the techniques of electron microscopy have developed so widely and rapidly that they now cover the fields of research once the unique ll:panage of sister research techniques such as biochemistry, physiology, immunology, X-ray diffraction, etc. It is now possible to reach molecular and submolecular levels, making this technique indispensable in every type of research. Electron microscopy alone often provides enough information to solve given problems. In the field of the connective tissue matrix, knowledge of the molecular structure of collagen, pro teoglycans and elastin and their interaction has been to a large extent elucidated by electron microscopy. The field over which electron microscopy ranges in the investigation of the connective tissue matrix is so wide that the aim of this volume is to collect the main ultrastructural acquisitions disseminated in various journals and monographs in one book. The intent ofthis volume is to: (a) integrate different and new microscopic methods and review the results of such an integrative approach; (b) present a comprehensive ultrastructural account of selected aspects of the field; (c) point out gaps or controversial topics in our knowledge; (d) outline pertinent future research and expansion of the subject.

Organization of the Extracellular Matrix

Author : Laszlo Modis
Publisher : CRC Press
ISBN 13 : 1351083732
Total Pages : 295 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Organization of the Extracellular Matrix by : Laszlo Modis

Download or read book Organization of the Extracellular Matrix written by Laszlo Modis and published by CRC Press. This book was released on 2018-05-04 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes analysis techniques and results of topics such as physical backgrounds, chemical backgrounds, and principal methods of topo-optical reactions used in ultrastructure research of the ECM; orientation patterns of GAGs and collagen in different tissues/cartilage, cornea, kidney basement membranes, and skin; factors involved in the formation of submicroscopically ordered matrix structure; and cell-matrix interactions, including cytoskeleton-cell-membrane-matrix relationships. A summarization of the advantages and limitations of polarization microscopy compared to electron microscopy in ultracellular research is also included. Cell biologists, histologists, pathologists, and biochemists in connective tissue research will find this book to be an invaluable reference tool.

Ultrastructure of Skeletal Tissues

Author : E. Bonucci
Publisher : Springer Science & Business Media
ISBN 13 : 1461314879
Total Pages : 302 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Ultrastructure of Skeletal Tissues by : E. Bonucci

Download or read book Ultrastructure of Skeletal Tissues written by E. Bonucci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The calcified tissues have fundamental functions in the biology of organisms, not only because their strength, solidity, and elasticity permit movement and mechanical activities, and protect soft tissues against traumatic forces, but also on account of their role in mineral homeostasis. For this reason, extensive investigation in the last 30 years has provided much to explain the complex chemical and physical processes occurring in cells and matrices composing the skeleton, and their alterations in pathological conditions. The use of ultrastructural methods such as immunocytochemistry, scanning and transmission electron microscopy, cytoautoradiography, freeze/fracture etching, high voltage, etc. has proven to be of great value when applied to cells and matrix components of bone and cartilage, in spite of the technical difficulties due to the hardness of these tissues. However, available information on this subject is disseminated in a variety of scientific and medical articles. This volume is an attempt to collect together the most significant data on the ultrastructure of cartilage and bone in normalcy and pathology. Obviously, it cannot be a complete report of all these data, its principal aim being that of: a) giving a comprehensive statement of the results concerning the basic structures common to these tissues, especially collagen fibrils, noncollagenous proteins, and proteoglycans, and their relationships with the mineral substance (for which another volume of this series can also be consulted; see Ruggeri A. , Motta P. M. (eds.

Connective Tissue Matrix

Author : David W. L. Hukins
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Connective Tissue Matrix by : David W. L. Hukins

Download or read book Connective Tissue Matrix written by David W. L. Hukins and published by . This book was released on 1990 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a sequel to Volume 5 of the series, Connective Tissue Matrix. The emphasis in the present volume is on changes which occur in connective tissue matrix and how its components influence biological properties. Changes include alteration of structure and loss of fluid, in response to mechanical loading, and biological changes occurring during development, degeneration and ageing. The chapters illustrate the wide range of disciplines involved in current research but are not intended to provide a comprehensive review of the subject. Volume 11 of the series, Calcified Tissue, deals with related tissues whose composition and properties are modified by calcification.

The Extracellular Matrix: an Overview

Author : Robert Mecham
Publisher : Springer Science & Business Media
ISBN 13 : 3642165559
Total Pages : 429 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis The Extracellular Matrix: an Overview by : Robert Mecham

Download or read book The Extracellular Matrix: an Overview written by Robert Mecham and published by Springer Science & Business Media. This book was released on 2011-02-16 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Functional Ultrastructure

Author : Margit Pavelka
Publisher : Springer Science & Business Media
ISBN 13 : 3211263926
Total Pages : 340 pages
Book Rating : 4.2/5 (112 download)

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Book Synopsis Functional Ultrastructure by : Margit Pavelka

Download or read book Functional Ultrastructure written by Margit Pavelka and published by Springer Science & Business Media. This book was released on 2005-12-05 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The period between 1950 and 1980 were the golden It also provides unique insights into how pathological years of transmission electron microscopy and pro- processes affect cell organization. duced a plethora of new information on the structure of This information is vital to current work in which cells that was coupled to and followed by biochemical the emphasis is on integrating approaches from p- and functional studies. TEM was king and each micro- teomics, molecular biology, molecular imaging and graph of a new object produced new information that physiology, and pathology to understand cell functions led to new insights on cell and tissue organization and and derangements in disease. In this current era, there is their functions. The quality of data represented by the a growing tendency to substitute modern light mic- images of cells and tissues had been perfected to a very scopic techniques for electron microscopy because it is high level by the great microscopists of the era including less technically demanding and is more readily available Palade, Porter, Fawcett, Sjostrand, Rhodin and many to researchers. This atlas reminds us that the infor- others. At present, the images that we see in leading tion obtained by electron microscopy is invaluable and journals for the most part do not reach the same techni- has no substitute.

Connective Tissue Disease

Author : Jouni Uitto
Publisher : CRC Press
ISBN 13 : 1000447227
Total Pages : 576 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Connective Tissue Disease by : Jouni Uitto

Download or read book Connective Tissue Disease written by Jouni Uitto and published by CRC Press. This book was released on 2021-07-29 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.

Structure and Function of the Extracellular Matrix

Author : Bela Suki
Publisher : Elsevier
ISBN 13 : 0128197161
Total Pages : 282 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Structure and Function of the Extracellular Matrix by : Bela Suki

Download or read book Structure and Function of the Extracellular Matrix written by Bela Suki and published by Elsevier. This book was released on 2021-12-08 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki's book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book. Examines the evolutionary origins and consequences of the extracellular matrix Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system Presents problems and a set of computational laboratory projects in various chapters to aid teaching and learning Provides an introduction to the properties and organization of the extracellular matrix components

Membranes, Mitochondria, and Connective Tissues

Author : Isidore Gersh
Publisher : Elsevier
ISBN 13 : 0323158625
Total Pages : 264 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Membranes, Mitochondria, and Connective Tissues by : Isidore Gersh

Download or read book Membranes, Mitochondria, and Connective Tissues written by Isidore Gersh and published by Elsevier. This book was released on 2012-12-02 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Submicroscopic Cytochemistry, Volume II: Membranes, Mitochondria, and Connective Tissues presents laboratory findings and theoretical aspects of the cytochemistry of cellular membranes, mitochondria, and connective tissues. Emphasis is on the molecular and macromolecular organization of cellular membranes, along with the origin and distribution of the major macromolecular aggregates of connective tissue. This volume consists of 11 chapters and begins by discussing the results of cytochemical studies on lipid and protein components of membranes in acinar and hepatic cells of the murine pancreas. The following chapters focus on densitometric studies of lipid membranes in pancreatic acinar cells of the mouse; the distribution of lipids and proteins in mitochondria of hepatic and exocrine pancreatic cells of adult mice, and of nucleic acids in mitochondria of embryonic cells; and possible precursor granules in fibroblasts, chondrocytes, and osteoblasts. The distribution of DNA and of soluble and insoluble RNAs in chondrocytes of the epiphyseal plate of the rat tibia is also examined, along with vascularity in tendons of young rats. This monograph will be of interest to cytochemists, biochemists, and molecular biologists.

Methods in Extracellular Matrix Biology

Author :
Publisher : Academic Press
ISBN 13 : 0128122986
Total Pages : 470 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Methods in Extracellular Matrix Biology by :

Download or read book Methods in Extracellular Matrix Biology written by and published by Academic Press. This book was released on 2018-01-05 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Extra Cellular Matrix, Volume 142, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections devoted to Elastin, Quantification of collagen and elastin, Fibrillins, Lysyl oxidase, Fibulins, Matrilins, Hyaluronic Acid, Small leucine-rich proteoglycans, Syndecans, Fibronectin, SPARC, Thrombospondins, Tenascins, Collagen IV, Multi-photon analysis of ECM, Cell-derived extracellular matrices, Laminins, Fibrillar Collagens, Imaging ECM in developing embryos, Analysis of Matrix Degradation, Ultrastructural analysis of ECM, Versican and Large proteoglycans, and an ECM crosslink analysis. This series covers a wide array of topics about the extracellular matrix, including an understanding of crucial proteins and glycoproteins components of ECM. Contains contributions from experts in the field from across the world Covers a wide array of topics on the extracellular matrix, including an understanding crucial proteins and the glycoproteins components of ECM Includes analysis based topics, such as quantification of collagen and elastin, mulit-photon analysis of ECM and ECM crosslink analysis

Ultrastructure of Smooth Muscle

Author : P. Motta
Publisher : Springer Science & Business Media
ISBN 13 : 1461306833
Total Pages : 258 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Ultrastructure of Smooth Muscle by : P. Motta

Download or read book Ultrastructure of Smooth Muscle written by P. Motta and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in electron microscopy have opened up new dimensions and perspectives in the field of morphology, and these are presently being integrated with biochemical and physiopathological phenomena occurring in cells, tissues, and organs. Methods such as freeze-fracture, freeze-etching, scanning, and high-voltage electron microscopy have contributed immensely to this progress, as well as to the study of smooth muscle tissue and contractile cells in general. The articles composing this book have been selected and edited with the purpose of updating and reviewing the most important aspects of smooth muscle cells as revealed by the integration of these submicroscopic techniques. The chapters of this volume have been prepared by some of the most authoritative experts in the discipline. Therefore each article not only offers the reader a concise review of the specific topic, but also seeks to highlight areas that require further investigation. Much of the volume is presented in an illustrative format so as to emphasize the remarkable results obtainable by the combination of the aforementioned methods, which allow a better appreciation of smooth muscle structure and ultrastructure. This volume, like others in the series, is intended not only for researchers in the field, but also for graduate students of histology, embryology, anatomy, physiology, and pathology in both medical and veterinary colleges. My hope is that this book will prove to be a valuable academic resource to the audience of the world in this fascinating and expanding field.

Functional Ultrastructure

Author : Margit Pavelka
Publisher : Springer Science & Business Media
ISBN 13 : 3211993908
Total Pages : 366 pages
Book Rating : 4.2/5 (119 download)

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Book Synopsis Functional Ultrastructure by : Margit Pavelka

Download or read book Functional Ultrastructure written by Margit Pavelka and published by Springer Science & Business Media. This book was released on 2010-07-16 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.

Connective Tissue

Author : M.B. Mathews
Publisher : Springer Science & Business Media
ISBN 13 : 3642809049
Total Pages : 332 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Connective Tissue by : M.B. Mathews

Download or read book Connective Tissue written by M.B. Mathews and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals primarily with the principal extracellular macromole cules of animal connective tissues. It attempts to answer some general questions about the biological organization of the tissues: What is the nature of this organization at various dimensional levels? What functions does the organization serve? How has it evolved? I have given major emphasis to the structures and properties of the macromolecular components of extracellular matrices from a wide range of invertebrates and vertebrates. In doing so, however, I have treated cursorily many important aspects of connective tissue biology that appeared to be only indirectly relevant to the principal questions asked. On the other hand, I have not hesitated to search for broad biological principles outside the prevailing conceptual boundaries of animal connective tissues and the lower molecular dimensional levels. The numerous speculations presented will, I hope, stimulate the reader to further thought and investigation. Acknowledgements My previously unpublished data that have been included in this volume could not have been obtained without the generous gifts of specimens and other assistance by a number of individuals and institutions. These are Dr. G. BERENSON of Louisiana State University, Drs. W. P. BRAKER and D. ZUMWALD of the Shedd Aquarium, Dr. S. H. CHUANG of the Univer sity of Singapore, Dr. L. G. CLARK and Mr. U. M. VARELA-DIAZ of the University of Pennsylvania, the Government of Nicaragua, Dr. E. CLARK of Cape Haze Marine Laboratories, Mr. C. E.

Postgraduate Orthopaedics

Author : Paul A. Banaszkiewicz
Publisher : Cambridge University Press
ISBN 13 : 1107627362
Total Pages : 301 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Postgraduate Orthopaedics by : Paul A. Banaszkiewicz

Download or read book Postgraduate Orthopaedics written by Paul A. Banaszkiewicz and published by Cambridge University Press. This book was released on 2012-08-16 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The must-have book for candidates preparing for the oral component of the FRCS (Tr and Orth).

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fine Structure of Cells and Tissues

Author : Keith R. Porter
Publisher :
ISBN 13 :
Total Pages : 220 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fine Structure of Cells and Tissues by : Keith R. Porter

Download or read book Fine Structure of Cells and Tissues written by Keith R. Porter and published by . This book was released on 1973 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the collaboration of Susan A. Badenhausen in transmission electron microscopy and Peter Andrews in scanning electron microscopy.

Cell Biology of Extracellular Matrix

Author : E.D. Hay
Publisher : Springer Science & Business Media
ISBN 13 : 1461537703
Total Pages : 478 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Cell Biology of Extracellular Matrix by : E.D. Hay

Download or read book Cell Biology of Extracellular Matrix written by E.D. Hay and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .