Twenty Years of G-CSF

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3034802188
Total Pages : 478 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Twenty Years of G-CSF by : Graham Molineux

Download or read book Twenty Years of G-CSF written by Graham Molineux and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting. This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.

Twenty Years of G-CSF

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Author :
Publisher : Springer
ISBN 13 : 9783034802192
Total Pages : 478 pages
Book Rating : 4.8/5 (21 download)

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Book Synopsis Twenty Years of G-CSF by : Graham Molineux

Download or read book Twenty Years of G-CSF written by Graham Molineux and published by Springer. This book was released on 2012-01-26 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting. This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.

Twenty Years of G-CSF

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 303480217X
Total Pages : 476 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Twenty Years of G-CSF by : Graham Molineux

Download or read book Twenty Years of G-CSF written by Graham Molineux and published by Springer Science & Business Media. This book was released on 2012-01-07 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting. This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.

The EBMT Handbook

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Author :
Publisher :
ISBN 13 : 9781013273674
Total Pages : 688 pages
Book Rating : 4.2/5 (736 download)

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Book Synopsis The EBMT Handbook by : Nicolaus Kröger

Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

The EBMT Handbook

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Author :
Publisher : Springer Nature
ISBN 13 : 3031440803
Total Pages : 840 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis The EBMT Handbook by : Anna Sureda

Download or read book The EBMT Handbook written by Anna Sureda and published by Springer Nature. This book was released on with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evidence-Based Hematology

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Publisher : John Wiley & Sons
ISBN 13 : 9781444300864
Total Pages : 440 pages
Book Rating : 4.3/5 (8 download)

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Book Synopsis Evidence-Based Hematology by : Mark A. Crowther

Download or read book Evidence-Based Hematology written by Mark A. Crowther and published by John Wiley & Sons. This book was released on 2009-01-30 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique new book uses a series of focussed questions, comprehensive literature evaluations and structured grades of recommendation to provide evidence for the treatment of hematological disorders, both malignant and benign. With contributions from leading international experts who have a real understanding of evidence-based medicine the book provides comprehensive reviews accompanied by clinical commentaries and recommendations on the best treatment regimes to adopt for individual patients. The book is split into two sections: the first examines the methodology underlying evidence based practice, and the second concentrates on the clinical practice of hematology, providing current “best evidence” to guide practice in a series of well-defined clinical situations. This clinical reference is an invaluable source of evidence-based information distilled into guidance for clinical practice which will be welcomed by practitioners, trainees and associated health professionals.

Patient Blood Management

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Publisher : Thieme
ISBN 13 : 3132004510
Total Pages : 494 pages
Book Rating : 4.1/5 (32 download)

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Book Synopsis Patient Blood Management by : Hans Gombotz

Download or read book Patient Blood Management written by Hans Gombotz and published by Thieme. This book was released on 2015-11-10 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient Blood Management (PBM) is an innovative clinical concept that aims to reduce the need for allogenic blood transfusions, cut health-care costs, and avert or correct the risk factors related to blood transfusion, thus minimizing the rate of side effects and complications. This comprehensive hands-on volume offers a three-point approach for the implementation of PBM to improve patient outcome, focusing on how to prevent or treat anemia, reduce blood loss, and increase anemia tolerance. The book also goes beyond preoperative PBM, with detailed accounts of coagulation disorder management and the administration of coagulation products and platelet concentrates. Special Features: Presents a clear three-pillar strategy for the application of PBM: diagnosis and treatment of anemia, reduction of peri-interventional blood loss, and optimization of the tolerance to anemia in the everyday clinical setting Covers issues such as PBM during surgery, requirements for modern transfusion medicine, ordering blood products, the role of pre-anesthesia clinics, benchmarking processes, and potential implications of PBM in the public health sector Overview of research in PBM including landmark studies and current clinical trials Boxes in each chapter highlighting key information, core statements, and summaries A multidisciplinary and international team of contributors experienced in PBM Patient Blood Management is a guide for clinicians and residents whose patients are at risk for anemia, coagulation disorders, or severe blood loss. Anesthesiologists, surgeons, and specialists involved in the use of blood and blood products can use the book for quick reference or to learn more about a leading-edge concept for optimizing patient safety and improving outcome.

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1422 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fetal & Neonatal Hematology, Oncology and Immunology

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Author :
Publisher : JP Medical Ltd
ISBN 13 : 9386322765
Total Pages : 495 pages
Book Rating : 4.3/5 (863 download)

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Book Synopsis Fetal & Neonatal Hematology, Oncology and Immunology by : MR Lokeshwar

Download or read book Fetal & Neonatal Hematology, Oncology and Immunology written by MR Lokeshwar and published by JP Medical Ltd. This book was released on 2017-07-17 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to the diagnosis and treatment of blood and immunological disorders and cancer in foetuses and newborns. Divided into eight sections, the text begins with detailed discussion on foetal haematology, antenatal diagnosis of disorders, red blood cell disorders and anaemia in the newborn, and coagulation and platelet conditions. The following chapters cover foetal and neonatal malignancies and blood transfusion, followed by a final section on immunological disorders. Each topic explains new advances, all current treatment protocols, new drugs, and management approaches. Chapters are further enhanced by clinical images and tables. Key points Comprehensive guide to diagnosis and treatment of blood and immunological disorders and cancer in foetuses and newborns Presented in an easy to follow format, explaining new advances, treatment protocols, new drugs, and management approaches Includes discussion on neonatal malignancies and blood transfusion Highly illustrated with clinical images and tables

Practical Geriatric Oncology

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Publisher : Cambridge University Press
ISBN 13 : 1139490591
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Practical Geriatric Oncology by : Arti Hurria

Download or read book Practical Geriatric Oncology written by Arti Hurria and published by Cambridge University Press. This book was released on 2010-09-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The risk of cancer increases with age, and the number of older adults seeking treatment is increasing dramatically in line with the aging population. The care of older patients differs from that of younger adults because of differences in the biology of the tumor, age-related differences in host physiology, comorbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Practical Geriatric Oncology is a comprehensive, evidence-based text that synthesizes the growing literature in this field and provides practical guidelines to the care of older adults with cancer. Coverage includes patient assessment, management of solid tumors and hematologic malignancies, the impact of age on the pharmacology of cancer therapy, surgical oncology and radiation oncology in the older adult, symptom management and supportive care. In addition to serving as core reading for oncologists and hematologists, the book will also be a useful work for other healthcare professionals who provide oncology care, including surgeons, radiation oncologists, palliative care doctors, primary care providers, geriatricians and nurses.

Childhood Acute Lymphoblastic Leukemia

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Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 342 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Classic Papers in Orthopaedics

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Publisher : Springer Science & Business Media
ISBN 13 : 1447154517
Total Pages : 527 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Classic Papers in Orthopaedics by : Paul A. Banaszkiewicz

Download or read book Classic Papers in Orthopaedics written by Paul A. Banaszkiewicz and published by Springer Science & Business Media. This book was released on 2014-01-10 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orthopedic experts in their field have carefully chosen what they consider to be the key papers in their respective domains. Every paper is carefully described and evaluated by its strengths, weaknesses and its contribution to the field. Papers have been chosen by number of citations, academic importance, articles that have changed our whole way of thinking or that have simply stood the test of time.

The Orexin System. Basic Science and Role in Sleep Pathology

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068446
Total Pages : 165 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis The Orexin System. Basic Science and Role in Sleep Pathology by : M.A. Steiner

Download or read book The Orexin System. Basic Science and Role in Sleep Pathology written by M.A. Steiner and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

Nathan and Oski's Hematology of Infancy and Childhood

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Author :
Publisher : Saunders
ISBN 13 :
Total Pages : 1092 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nathan and Oski's Hematology of Infancy and Childhood by : Stuart H. Orkin

Download or read book Nathan and Oski's Hematology of Infancy and Childhood written by Stuart H. Orkin and published by Saunders. This book was released on 1998 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated edition of a long-time classic in the field of infant and childhood hematology. The text has been reorganized, a new editor has collaborated with Dr. Nathan and 30 new chapter authors have been added. It is still the most complete clinical reference available on the subject!

Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy

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Author :
Publisher : Springer Nature
ISBN 13 : 3030644928
Total Pages : 181 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy by : Mahmoud Aljurf

Download or read book Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy written by Mahmoud Aljurf and published by Springer Nature. This book was released on 2021-02-19 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Specific areas of focus include document development and implementation, audits and validation, performance measurement, writing a quality management plan, the accreditation process, data management, and maintaining a quality management program. Written by experts in the field, Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy: A Practical Guide is a valuable resource for physicians, healthcare professionals, and laboratory staff involved in the creation and maintenance of a state-of-the-art HSCT and cellular therapy program.

Stem Cells and Cancer Stem Cells, Volume 6

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Publisher : Springer Science & Business Media
ISBN 13 : 9400729928
Total Pages : 445 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Stem Cells and Cancer Stem Cells, Volume 6 by : M.A. Hayat

Download or read book Stem Cells and Cancer Stem Cells, Volume 6 written by M.A. Hayat and published by Springer Science & Business Media. This book was released on 2012-02-29 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The difference among pluripotent stem cells, multipotent stem cells, and unipotent stem cells is pointed out. Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: human embryonic stem cells, human mesenchymal stem cells, germ cell-derived pluripotent stem cells, induced pluripotent stem cells, human umbilical cord blood-derived stem cells, breast tumor stem cells,and hematopoietic stem cells. Because of the potential of human embryonic stem cells to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential. Because of their pluripotency, these cells have been used in various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. The formation of embryoid bodies, which are three-dimensional aggregates of embryonic stem cells, is explained as this is the first step in cell differentiation. Such embryoid body culture has been widely used as a trigger for the in vitro differentiation of embryonic stem cells. The basic capacity of self-renewal of human embryogenic stem cells is explained. The role of TGF-beta in the propagation of human embryonic stem cells is discussed. The differentiation of human embryonic stem cells into neurons, hepatocytes, cardiomyocytes, and retinal cells is fully explained. Donor policies for hematopoietic stem cells are also explained.